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pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Engineered HMGB1 construct with tandem Box B domains promotes tissue regeneration without potential for inflammation

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pmc.ncbi.nlm.nih.gov/articles/PMC13486833/
Jun 2026
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Cuproptosis-immunity crosstalk informs strategy to overcome immunotherapy resistance

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sciencedirect.com/science/article/pii/S0092867426006367
Mar 2026
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KLS-3021, a multifunctional oncolytic virus, demonstrates potent early-intervention efficacy in preclinical models of prostate-confined and locally advanced prostate cancer

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pmc.ncbi.nlm.nih.gov/articles/PMC12945804/
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Early HMGB1 Inhibition Reduces Hippocampal Injury During Adolescence in a Young Mouse Model of Radiation-Induced Brain Injury

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pmc.ncbi.nlm.nih.gov/articles/PMC12946357/
Feb 2026
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High‐mobility Group Protein 1/ Receptor for Advanced Glycation End Products/ Nuclear Factor‐κB Signalling Pathway Contributes to the Pathogenic Process of Striatal Neuron Impairment in the Rat Model of Parkinson's Disease

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pmc.ncbi.nlm.nih.gov/articles/PMC12856231/
Oct 2025
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2025.09.25.678487v1.full-html.html

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54.241.53.176/6242d0964f3f11ac8334753a1121987506367c6b/2025.09.25.678487v1.full-html.html
Sep 2025
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A potent NLRP3 inhibitor effective against both MCC950-sensitive and -resistant inflammation

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sciencedirect.com/science/article/pii/S2451945625002594
52.53.155.43 52.53.155.43

2025.08.28.672784v1.full-html.html

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52.53.155.43/ac7f1767c23c6666ccfc705d09859fa9a6162a49/2025.08.28.672784v1.full-html.html
Jul 2025
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Direct interaction of HMGB1 with SARS-CoV-2 facilitates its infection via RAGE-dependent endocytosis

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sciencedirect.com/science/article/pii/S2589004225013240
Jun 2025
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HMGB1-BoxA gene therapy in reversing cisplatin resistance in non-small cell lung cancer

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  DOI: 10.1371/journal.pone.0327144
  
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Probiotic-mediated tumor microenvironment reprogramming with protease-sensitive interleukin-15 and photothermal therapy

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pmc.ncbi.nlm.nih.gov/articles/PMC12208336/
Mar 2025
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

7 I, a structurally modified sinomenine, exerts dual anti-GBM effects by inhibiting glioblastoma proliferation and inducing necroptosis which further mediates lysosomal cell death

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  DOI: 10.1111/bph.17464
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.17464
Jan 2025
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Extracellular vesicles from mesenchymal stem cells improve liver injury in rats with mild liver damage. Underlying mechanisms and role of TGFβ

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sciencedirect.com/science/article/pii/S0024320525000621
Dec 2024
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BPS Publications

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  DOI: 10.1111/bph.17402
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.17402
Nov 2024
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AMPK regulates Bcl2-L-13-mediated mitophagy induction for cardioprotection

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  DOI: 10.1016/j.celrep.2024.115001
  
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sciencedirect.com/science/article/pii/S2211124724013524
Nov 2023
www.biorxiv.org www.biorxiv.org

Endonucleosis mediates internalization of cytoplasm into the nucleus in senescent cells

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  DOI: 10.1101/2023.11.12.566736
  
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biorxiv.org/content/10.1101/2023.11.12.566736v1
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APOE4-promoted gliosis and degeneration in tauopathy are ameliorated by pharmacological inhibition of HMGB1 release

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1. scibot 02 Nov 2023
  
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  DOI: 10.1016/j.celrep.2023.113252
  
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sciencedirect.com/science/article/pii/S2211124723012640
Sep 2023
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Effects of HMGB1/RAGE/cathespin B inhibitors on alleviating hippocampal injury by regulating microglial pyroptosis and caspase activation in neonatal hypoxic–ischemic brain damage

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  DOI: 10.1111/jnc.15965
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.15965
Jul 2023
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Interventional hydrogel microsphere vaccine as an immune amplifier for activated antitumour immunity after ablation therapy

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ncbi.nlm.nih.gov/pmc/articles/PMC10336067/
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QHRD106 ameliorates ischemic stroke injury as a long-acting tissue kallikrein preparation

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sciencedirect.com/science/article/pii/S2589004223013457
May 2023
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Hub genes and key pathways of traumatic brain injury:... : Neural Regeneration Research

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pmc.ncbi.nlm.nih.gov/articles/PMC11826463/
Apr 2023
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The p-rpS6-zone delineates wounding responses and the healing process

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Targeting the mevalonate pathway suppresses ARID1A-inactivated cancers by promoting pyroptosis

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sciencedirect.com/science/article/pii/S1535610823000508
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Oxylipin-PPARγ-initiated adipocyte senescence propagates secondary senescence in the bone marrow

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pmc.ncbi.nlm.nih.gov/articles/PMC10127143/
Jan 2023
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Tyrosine kinase inhibitors can activate the NLRP3 inflammasome in myeloid cells through lysosomal damage and cell lysis

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  DOI: 10.1126/scisignal.abh1083
  
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science.org/doi/10.1126/scisignal.abh1083
Oct 2022
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Histamine induced high mobility group box-1 release from vascular endothelial cells through H1 receptor

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ncbi.nlm.nih.gov/pmc/articles/PMC9583674/
Sep 2022
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Posttranslational S-nitrosylation modification regulates HMGB1 secretion and promotes its proinflammatory and neurodegenerative effects

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sciencedirect.com/science/article/pii/S2211124722011585
Mar 2022
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Age-dependent release of high-mobility group box protein-1 and cellular neuroinflammation after traumatic brain injury in mice

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  DOI: 10.1002/cne.24589
  
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Paracrine signal emanating from stressed cardiomyocytes aggravates inflammatory microenvironment in diabetic cardiomyopathy

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Human biliary epithelial cells from discarded donor livers rescue bile duct structure and function in a mouse model of biliary disease

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  DOI: 10.1016/j.stem.2022.02.006
  
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sciencedirect.com/science/article/pii/S1934590922000571
Jan 2022
clincancerres.aacrjournals.org clincancerres.aacrjournals.org

Modulation of the Human Pancreatic Ductal Adenocarcinoma Immune Microenvironment by Stereotactic Body Radiotherapy

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  DOI: 10.1158/1078-0432.CCR-21-2495
  
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clincancerres.aacrjournals.org/content/28/1/150
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MEK inhibition overcomes chemoimmunotherapy resistance by inducing CXCL10 in cancer cells

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  DOI: 10.1016/j.ccell.2021.12.009
  
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sciencedirect.com/science/article/pii/S1535610821006620
Nov 2021
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DFF40 deficiency in cancerous T cells is implicated in chemotherapy drug sensitivity and resistance through the regulation of the apoptotic pathway

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  DOI: 10.1016/j.bcp.2021.114801
  
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sciencedirect.com/science/article/pii/S0006295221004172
Aug 2021
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A genotype-phenotype screening system using conditionally immortalized immature dendritic cells

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1. scibot 13 Aug 2021
  
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sciencedirect.com/science/article/pii/S2666166721004391
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Aging-associated genes and let-7 microRNAs: a contribution to myogenic program dysregulation in oculopharyngeal muscular dystrophy

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Tau oligomer induced HMGB1 release contributes to cellular senescence and neuropathology linked to Alzheimer’s disease and frontotemporal dementia

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Toll-like receptor 2 activation and up-regulation by high mobility group box-1 contribute to post-operative neuroinflammation and cognitive dysfunction in mice

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Aging‐associated genes and let‐7 microRNAs: a contribution to myogenic program dysregulation in oculopharyngeal muscular dystrophy

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Recombinant Thrombomodulin Attenuates Preeclamptic Symptoms by Inhibiting High Mobility Group Box 1 in Mice

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Arctigenin protects against depression by inhibiting microglial activation and neuroinflammation via HMGB1/TLR4/NF‐κB and TNF‐α/TNFR1/NF‐κB pathways

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Genome-wide CRISPR Screens Reveal Host Factors Critical for SARS-CoV-2 Infection

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HMGB1 amplifies ILC2-induced type-2 inflammation and airway smooth muscle remodelling

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O-GlcNAc Transferase Suppresses Inflammation and Necroptosis by Targeting Receptor-Interacting Serine/Threonine-Protein Kinase 3

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Aster Proteins Facilitate Nonvesicular Plasma Membrane to ER Cholesterol Transport in Mammalian Cells

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PINK1 and PARK2 Suppress Pancreatic Tumorigenesis through Control of Mitochondrial Iron-Mediated Immunometabolism

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Cancer-Germline Antigen Expression Discriminates Clinical Outcome to CTLA-4 Blockade

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jneuroinflammation.biomedcentral.com jneuroinflammation.biomedcentral.com

Inhibition of HMGB1 reduces rat spinal cord astrocytic swelling and AQP4 expression after oxygen-glucose deprivation and reoxygenation via TLR4 and NF-κB signaling in an IL-6-dependent manner

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jneuroinflammation.biomedcentral.com/articles/10.1186/s12974-017-1008-1
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A Novel, Noninvasive, Predictive Epilepsy Biomarker with Clinical Potential

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