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May 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Temperature-specific regulation of the NDR kinase Orb6 by the MAPK Sty1 to promote heat stress resilience

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1. scibot 09 May 2026
  
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  DOI: 10.1242/jcs.264507
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13143207/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

mRNA lipid-nanoparticle-mediated mitochondrial apoptosis augments adoptive T cell immunotherapy

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  DOI: 10.1016/j.xcrm.2026.102706
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13130659/
Feb 2026
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SIRT1 mediates brain metabolic and developmental consequences of methionine synthase deficiency in inborn errors of cobalamin metabolism

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  DOI: 10.1016/j.xcrm.2026.102643
  
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sciencedirect.com/science/article/pii/S2666379126000601
Sep 2025
www.biorxiv.org www.biorxiv.org

Metabolic Crossroads: AMDHD2 Couples the Hexosamine Biosynthetic Pathway to Acetyl-CoA Homeostasis in Pluripotent Stem Cells

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1. scibot 12 Sep 2025
  
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  DOI: 10.1101/2025.08.20.671247
  
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biorxiv.org/content/10.1101/2025.08.20.671247v1
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Control of stress-activated Cdc42 dynamics by the MAP kinase Sty1—NDR kinase Orb6 regulatory axis

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  DOI: 10.1016/j.isci.2025.113298
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12397940/
Jun 2025
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Epigenetic regulation of intracellular branched-chain amino acid homeostasis maintains a normal lifespan

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  DOI: 10.1016/j.isci.2025.112846
  
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sciencedirect.com/science/article/pii/S2589004225011071
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Cryptic phosphoribosylase activity of NAMPT restricts the virion incorporation of viral proteins

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  DOI: 10.1038/s42255-024-01162-0
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12085970/
www.cell.com www.cell.com

Off-pore Nup98 condensates mobilize heterochromatic breaks and exclude Rad51

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  DOI: 10.1016/j.molcel.2025.05.012
  
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cell.com/molecular-cell/abstract/S1097-2765(25)00446-0
May 2025
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Paraoxonase-like APMAP maintains endoplasmic-reticulum-associated lipid and lipoprotein homeostasis

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1. scibot 17 May 2025
  
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  DOI: 10.1016/j.devcel.2025.04.008
  
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sciencedirect.com/science/article/pii/S1534580725002102
Apr 2025
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Remote limb ischemic conditioning alleviates steatohepatitis via extracellular vesicle-mediated muscle-liver crosstalk

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  DOI: 10.1016/j.cmet.2025.02.009
  
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sciencedirect.com/science/article/pii/S1550413125000671
Jan 2025
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OXCT1 succinylation and activation by SUCLA2 promotes ketolysis and liver tumor growth

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1. scibot 28 Jan 2025
  
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  DOI: 10.1016/j.molcel.2024.12.025
  
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sciencedirect.com/science/article/pii/S1097276524010669
Dec 2024
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African ancestry neurodegeneration risk variant disrupts an intronic branchpoint in GBA1

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1. scibot 17 Dec 2024
  
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  DOI: 10.1038/s41594-024-01423-2
  
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link.springer.com/article/10.1038/s41594-024-01423-2
Aug 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Intergenerational Epigenetic Inheritance Mediated by MYS-2/MOF in the Pathogenesis of Alzheimer’s Disease

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1. scibot 21 Aug 2024
  
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  DOI: 10.1016/j.isci.2024.110588
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11363564/
Jun 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Xbp1 targets canonical UPRER and non-canonical pathways in separate tissues to promote longevity

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1. scibot 05 Jun 2024
  
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  DOI: 10.1016/j.isci.2024.109962
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11144730/
May 2024
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A computational pipeline for identifying gene targets and signalling pathways in cancer cells to improve lymphocyte infiltration and immune checkpoint therapy efficacy

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1. scibot 30 May 2024
  
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  DOI: 10.1016/j.ebiom.2024.105167
  
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sciencedirect.com/science/article/pii/S2352396424002020
Mar 2024
elifesciences.org elifesciences.org

Downregulation of Dickkopf-3, a Wnt antagonist elevated in Alzheimer's disease, restores synapse integrity and memory in a disease mouse model

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1. scibot 01 Mar 2024
  
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  DOI: 10.7554/eLife.89453
  
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  DOI: 10.7554/eLife.89453
  
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elifesciences.org/articles/89453
Feb 2024
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The GATOR2 complex maintains lysosomal-autophagic function by inhibiting the protein degradation of MiT/TFEs

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1. scibot 08 Feb 2024
  
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  DOI: 10.1016/j.molcel.2024.01.012
  
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sciencedirect.com/science/article/pii/S1097276524000480
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Mutations in the non-catalytic polyproline motif destabilize TREX1 and amplify cGAS-STING signaling

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1. scibot 01 Feb 2024
  
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  DOI: 10.1101/2024.01.04.574136
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10802300/
Sep 2023
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Systematic profiling of dominant ubiquitin variants reveals key functional nodes contributing to evolutionary selection

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  DOI: 10.1016/j.celrep.2023.113064
  
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sciencedirect.com/science/article/pii/S2211124723010756
Aug 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Two RNA-binding proteins mediate the sorting of miR223 from mitochondria into exosomes

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1. scibot 10 Aug 2023
  
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  DOI: 10.7554/eLife.85878
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10403255/
Mar 2023
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Development of a new surgical technique to infuse kynurenic acid to optic nerves in chickens for studying loss of myelination

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1. scibot 11 Mar 2023
  
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  DOI: 10.1016/j.heliyon.2023.e14361
  
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sciencedirect.com/science/article/pii/S2405844023015682
www.biorxiv.org www.biorxiv.org

Two RNA-binding proteins mediate the sorting of miR223 from mitochondria into exosomes

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  DOI: 10.1101/2023.01.11.523558
  
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biorxiv.org/content/10.1101/2023.01.11.523558v1
Feb 2023
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An engineered variant of MECR reductase reveals indispensability of long-chain acyl-ACPs for mitochondrial respiration

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1. scibot 08 Feb 2023
  
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  DOI: 10.1038/s41467-023-36358-7
  
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nature.com/articles/s41467-023-36358-7
Oct 2022
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Structure and functionality of a multimeric human COQ7:COQ9 complex

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1. scibot 28 Oct 2022
  
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  DOI: 10.1016/j.molcel.2022.10.003
  
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sciencedirect.com/science/article/pii/S1097276522009601
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Machine learning-assisted elucidation of CD81–CD44 interactions in promoting cancer stemness and extracellular vesicle integrity

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  DOI: 10.7554/eLife.82669
  
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elifesciences.org/articles/82669
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In situ cell-type-specific cell-surface proteomic profiling in mice

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1. scibot 11 Oct 2022
  
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  DOI: 10.1016/j.neuron.2022.09.025
  
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sciencedirect.com/science/article/pii/S0896627322008649
Jul 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Trans-splicing facilitated by RNA pairing greatly expands sDscam isoform diversity but not homophilic binding specificity

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  DOI: 10.1126/sciadv.abn9458
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9258826/
Jun 2022
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Active APPL1 sequestration by Plasmodium favors liver-stage development

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  DOI: 10.1016/j.celrep.2022.110886
  
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sciencedirect.com/science/article/pii/S2211124722006611
Mar 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Peripheral nerve fibroblasts secrete neurotrophic factors to promote axon growth of motoneurons

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  DOI: 10.4103/1673-5374.332159
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8820717/
Feb 2022
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Immune translational control by CPEB4 regulates intestinal inflammation resolution and colorectal cancer development

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  DOI: 10.1016/j.isci.2022.103790
  
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  DOI: 10.1016/j.isci.2022.103790
  
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sciencedirect.com/science/article/pii/S2589004222000608
Jan 2022
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Recruitment of MLL1 complex is essential for SETBP1 to induce myeloid transformation

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  DOI: 10.1016/j.isci.2021.103679
  
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sciencedirect.com/science/article/pii/S2589004221016497
Dec 2021
elifesciences.org elifesciences.org

Selective sorting of microRNAs into exosomes by phase-separated YBX1 condensates

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  DOI: 10.7554/eLife.71982
  
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elifesciences.org/articles/71982
Aug 2021
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Sex-specific regulation of spine density and synaptic proteins by G-protein-coupled estrogen receptor (GPER)1 in developing hippocampus

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1. scibot 15 Aug 2021
  
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  DOI: 10.1016/j.neuroscience.2021.07.035
  
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sciencedirect.com/science/article/pii/S0306452221003894
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CLOCKWORK ORANGE promotes CLOCK-CYCLE activation via the putative Drosophila ortholog of CLOCK INTERACTING PROTEIN CIRCADIAN

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1. scibot 15 Aug 2021
  
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  DOI: 10.1016/j.cub.2021.07.017
  
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sciencedirect.com/science/article/pii/S0960982221009726
www.fasebj.org www.fasebj.org

Aging-associated genes and let-7 microRNAs: a contribution to myogenic program dysregulation in oculopharyngeal muscular dystrophy

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1. scibot 14 Aug 2021
  
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  DOI: 10.1096/fj.201801577RR
  
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fasebj.org/doi/abs/10.1096/fj.201801577RR
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ncbi.nlm.nih.gov/pmc/articles/PMC5142118/
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FAF1 Regulates Antiviral Immunity by Inhibiting MAVS but Is Antagonized by Phosphorylation upon Viral Infection

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sciencedirect.com/science/article/pii/S1931312818305444
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Ipa1 Is an RNA Polymerase II Elongation Factor that Facilitates Termination by Maintaining Levels of the Poly(A) Site Endonuclease Ysh1

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Neuroendocrine Coordination of Mitochondrial Stress Signaling and Proteostasis

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The histone chaperone HIR maintains chromatin states to control nitrogen assimilation and fungal virulence

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sciencedirect.com/science/article/pii/S2211124721008196
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SUCLA2-coupled regulation of GLS succinylation and activity counteracts oxidative stress in tumor cells

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Aging‐associated genes and let‐7 microRNAs: a contribution to myogenic program dysregulation in oculopharyngeal muscular dystrophy

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Toll receptors remodel epithelia by directing planar-polarized Src and PI3K activity

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cGAS phase separation inhibits TREX1-mediated DNA degradation and enhances cytosolic DNA sensing

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Enhanced insulin signalling ameliorates C9orf72 hexanucleotide repeat expansion toxicity in Drosophila

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ER-directed TREX1 limits cGAS activation at micronuclei

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Genetic dissection of the mitochondrial lipoylation pathway in yeast

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Atg43 tethers isolation membranes to mitochondria to promote starvation-induced mitophagy in fission yeast

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CD200‐CD200R1 signaling pathway regulates neuroinflammation after stroke

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Plasma Leptin Reflects Progression of Neurofibrillary Pathology in Animal Model of Tauopathy

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Stress-activated MAPK signaling controls fission yeast actomyosin ring integrity by modulating formin For3 levels

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Acetylation-Dependent Deubiquitinase OTUD3 Controls MAVS Activation in Innate Antiviral Immunity

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Partial Inhibition of RNA Polymerase I Promotes Animal Health and Longevity

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Bab2 Functions as an Ecdysone-Responsive Transcriptional Repressor during Drosophila Development

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A Translocation Pathway for Vesicle-Mediated Unconventional Protein Secretion

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Impact of long‐lasting spontaneous physical activity on bone morphogenetic protein 4 in the heart and tibia in murine model of heart failure

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Sugar-Induced Obesity and Insulin Resistance Are Uncoupled from Shortened Survival in Drosophila

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Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains

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Miro1 Marks Parkinson’s Disease Subset and Miro1 Reducer Rescues Neuron Loss in Parkinson’s Models

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Rif1 S- acylation mediates DNA double-strand break repair at the inner nuclear membrane

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Mutual Zonated Interactions of Wnt and Hh Signaling Are Orchestrating the Metabolism of the Adult Liver in Mice and Human

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Influenza Virus Exploits an Interferon-Independent lncRNA to Preserve Viral RNA Synthesis through Stabilizing Viral RNA Polymerase PB1

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Untitled document

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Ipa1 Is an RNA Polymerase II Elongation Factor that Facilitates Termination by Maintaining Levels of the Poly(A) Site Endonuclease Ysh1

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Untitled document

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Untitled document

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Species-Specific Deamidation of cGAS by Herpes Simplex Virus UL37 Protein Facilitates Viral Replication

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Conserved Lipid and Small-Molecule Modulation of COQ8 Reveals Regulation of the Ancient Kinase-like UbiB Family

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Validation of a yeast malate dehydrogenase 2 (Mdh2) antibody tested for use in western blots

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E2F/DP Prevents Cell-Cycle Progression in Endocycling Fat Body Cells by Suppressing dATM Expression

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sciencedirect.com/science/article/pii/S1534580717309127
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Regulation of Androgen Receptor Activity by Transient Interactions of Its Transactivation Domain with General Transcription Regulators

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S096921261730360X
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Multi-omics Reveal Specific Targets of the RNA-Binding Protein Puf3p and Its Orchestration of Mitochondrial Biogenesis

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S2405471217305409
Nov 2017
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A Tubulin Binding Switch Underlies Kip3/Kinesin-8 Depolymerase Activity

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1. scibot 08 Nov 2017
  
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  Curator: @chewbeccax
  
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sciencedirect.com/science/article/pii/S1534580717304999
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Histone Mutants Separate R Loop Formation from Genome Instability Induction

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1. scibot 08 Nov 2017
  
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  AB_449644
  
  Curator: @Zeljana_Babic
  
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sciencedirect.com/science/article/pii/S1097276517303532
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Transgenerational programming of longevity through E(z)-mediated histone H3K27 trimethylation in Drosophila

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1. scibot 08 Nov 2017
  
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  mouse monoclonal anti-beta actin antibody (ab8224, Abcam)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5191882/
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The Ubiquitin Ligase CHIP Integrates Proteostasis and Aging by Regulation of Insulin Receptor Turnover

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1. scibot 08 Nov 2017
  
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  AB_449644
  
  Curator: @gabimpine
  
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sciencedirect.com/science/article/pii/S0092867417304154
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Spt5 Plays Vital Roles in the Control of Sense and Antisense Transcription Elongation

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1. scibot 08 Nov 2017
  
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  AB_449644
  
  Curator: @gabimpine
  
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elifesciences.org elifesciences.org

The fail-safe mechanism of post-transcriptional silencing of unspliced HAC1 mRNA

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1. scibot 08 Nov 2017
  
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  AB_449644
  
  Curator: @gabimpine
  
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elifesciences.org/articles/20069
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MECR Mutations Cause Childhood-Onset Dystonia and Optic Atrophy, a Mitochondrial Fatty Acid Synthesis Disorder

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1. scibot 08 Nov 2017
  
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  AB_449644
  
  Curator: @gabimpine
  
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sciencedirect.com/science/article/pii/S0002929716304347
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Loss of SynDIG1 Reduces Excitatory Synapse Maturation But Not Formation In Vivo

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1. scibot 08 Nov 2017
  
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  AB_449644
  
  Curator: @gabimpine
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5073248/

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