72 Matching Annotations
  1. Last 7 days
  2. link.springer.com link.springer.com
    African ancestry neurodegeneration risk variant disrupts an intronic branchpoint in GBA1
    1
    1. scibot 17 Dec 2024
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      DOI: 10.1038/s41594-024-01423-2

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    link.springer.com/article/10.1038/s41594-024-01423-2
  3. Aug 2024
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Intergenerational Epigenetic Inheritance Mediated by MYS-2/MOF in the Pathogenesis of Alzheimer’s Disease
    1
    1. scibot 21 Aug 2024
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      DOI: 10.1016/j.isci.2024.110588

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    pmc.ncbi.nlm.nih.gov/articles/PMC11363564/
  5. Jun 2024
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Xbp1 targets canonical UPRER and non-canonical pathways in separate tissues to promote longevity
    1
    1. scibot 05 Jun 2024
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      DOI: 10.1016/j.isci.2024.109962

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    ncbi.nlm.nih.gov/pmc/articles/PMC11144730/
  7. May 2024
  8. www.sciencedirect.com www.sciencedirect.com
    A computational pipeline for identifying gene targets and signalling pathways in cancer cells to improve lymphocyte infiltration and immune checkpoint therapy efficacy
    1
    1. scibot 30 May 2024
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      DOI: 10.1016/j.ebiom.2024.105167

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    sciencedirect.com/science/article/pii/S2352396424002020
  9. Mar 2024
  10. elifesciences.org elifesciences.org
    Downregulation of Dickkopf-3, a Wnt antagonist elevated in Alzheimer's disease, restores synapse integrity and memory in a disease mouse model
    2
    1. scibot 01 Mar 2024
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      DOI: 10.7554/eLife.89453

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    2. scibot 01 Mar 2024
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      DOI: 10.7554/eLife.89453

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    elifesciences.org/articles/89453
  11. Feb 2024
  12. www.sciencedirect.com www.sciencedirect.com
    The GATOR2 complex maintains lysosomal-autophagic function by inhibiting the protein degradation of MiT/TFEs
    1
    1. scibot 08 Feb 2024
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      DOI: 10.1016/j.molcel.2024.01.012

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    sciencedirect.com/science/article/pii/S1097276524000480
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mutations in the non-catalytic polyproline motif destabilize TREX1 and amplify cGAS-STING signaling
    1
    1. scibot 01 Feb 2024
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      DOI: 10.1101/2024.01.04.574136

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    ncbi.nlm.nih.gov/pmc/articles/PMC10802300/
  14. Sep 2023
  15. www.sciencedirect.com www.sciencedirect.com
    Systematic profiling of dominant ubiquitin variants reveals key functional nodes contributing to evolutionary selection
    1
    1. scibot 01 Sep 2023
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      DOI: 10.1016/j.celrep.2023.113064

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    sciencedirect.com/science/article/pii/S2211124723010756
  16. Aug 2023
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Two RNA-binding proteins mediate the sorting of miR223 from mitochondria into exosomes
    1
    1. scibot 10 Aug 2023
      RRID:AB_449644

      DOI: 10.7554/eLife.85878

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    ncbi.nlm.nih.gov/pmc/articles/PMC10403255/
  18. Mar 2023
  19. www.sciencedirect.com www.sciencedirect.com
    Development of a new surgical technique to infuse kynurenic acid to optic nerves in chickens for studying loss of myelination
    1
    1. scibot 11 Mar 2023
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      DOI: 10.1016/j.heliyon.2023.e14361

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    sciencedirect.com/science/article/pii/S2405844023015682
  20. www.biorxiv.org www.biorxiv.org
    Two RNA-binding proteins mediate the sorting of miR223 from mitochondria into exosomes
    1
    1. scibot 08 Mar 2023
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      DOI: 10.1101/2023.01.11.523558

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    biorxiv.org/content/10.1101/2023.01.11.523558v1
  21. Feb 2023
  22. www.nature.com www.nature.com
    An engineered variant of MECR reductase reveals indispensability of long-chain acyl-ACPs for mitochondrial respiration
    1
    1. scibot 08 Feb 2023
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      DOI: 10.1038/s41467-023-36358-7

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    nature.com/articles/s41467-023-36358-7
  23. Oct 2022
  24. www.sciencedirect.com www.sciencedirect.com
    Structure and functionality of a multimeric human COQ7:COQ9 complex
    1
    1. scibot 28 Oct 2022
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      DOI: 10.1016/j.molcel.2022.10.003

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    sciencedirect.com/science/article/pii/S1097276522009601
  25. elifesciences.org elifesciences.org
    Machine learning-assisted elucidation of CD81–CD44 interactions in promoting cancer stemness and extracellular vesicle integrity
    1
    1. scibot 20 Oct 2022
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      DOI: 10.7554/eLife.82669

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    elifesciences.org/articles/82669
  26. www.sciencedirect.com www.sciencedirect.com
    In situ cell-type-specific cell-surface proteomic profiling in mice
    1
    1. scibot 11 Oct 2022
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      DOI: 10.1016/j.neuron.2022.09.025

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    sciencedirect.com/science/article/pii/S0896627322008649
  27. Jul 2022
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Trans-splicing facilitated by RNA pairing greatly expands sDscam isoform diversity but not homophilic binding specificity
    1
    1. scibot 27 Jul 2022
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      DOI: 10.1126/sciadv.abn9458

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    ncbi.nlm.nih.gov/pmc/articles/PMC9258826/
  29. Jun 2022
  30. www.sciencedirect.com www.sciencedirect.com
    Active APPL1 sequestration by Plasmodium favors liver-stage development
    1
    1. scibot 03 Jun 2022
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      DOI: 10.1016/j.celrep.2022.110886

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    sciencedirect.com/science/article/pii/S2211124722006611
  31. Mar 2022
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Peripheral nerve fibroblasts secrete neurotrophic factors to promote axon growth of motoneurons
    1
    1. scibot 04 Mar 2022
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      DOI: 10.4103/1673-5374.332159

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    ncbi.nlm.nih.gov/pmc/articles/PMC8820717/
  33. Feb 2022
  34. www.sciencedirect.com www.sciencedirect.com
    Immune translational control by CPEB4 regulates intestinal inflammation resolution and colorectal cancer development
    2
    1. scibot 11 Feb 2022
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      DOI: 10.1016/j.isci.2022.103790

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      DOI: 10.1016/j.isci.2022.103790

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    sciencedirect.com/science/article/pii/S2589004222000608
  35. Jan 2022
  36. www.sciencedirect.com www.sciencedirect.com
    Recruitment of MLL1 complex is essential for SETBP1 to induce myeloid transformation
    1
    1. scibot 11 Jan 2022
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      DOI: 10.1016/j.isci.2021.103679

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    sciencedirect.com/science/article/pii/S2589004221016497
  37. Dec 2021
  38. elifesciences.org elifesciences.org
    Selective sorting of microRNAs into exosomes by phase-separated YBX1 condensates
    1
    1. scibot 01 Dec 2021
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      DOI: 10.7554/eLife.71982

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    elifesciences.org/articles/71982
  39. Aug 2021
  40. www.sciencedirect.com www.sciencedirect.com
    Sex-specific regulation of spine density and synaptic proteins by G-protein-coupled estrogen receptor (GPER)1 in developing hippocampus
    1
    1. scibot 15 Aug 2021
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      DOI: 10.1016/j.neuroscience.2021.07.035

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    sciencedirect.com/science/article/pii/S0306452221003894
  41. www.sciencedirect.com www.sciencedirect.com
    CLOCKWORK ORANGE promotes CLOCK-CYCLE activation via the putative Drosophila ortholog of CLOCK INTERACTING PROTEIN CIRCADIAN
    1
    1. scibot 15 Aug 2021
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      DOI: 10.1016/j.cub.2021.07.017

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    sciencedirect.com/science/article/pii/S0960982221009726
  42. www.fasebj.org www.fasebj.org
    Aging-associated genes and let-7 microRNAs: a contribution to myogenic program dysregulation in oculopharyngeal muscular dystrophy
    1
    1. scibot 14 Aug 2021
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      DOI: 10.1096/fj.201801577RR

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    fasebj.org/doi/abs/10.1096/fj.201801577RR
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 11 Aug 2021
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      DOI: 10.1016/j.ajhg.2016.09.021

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    ncbi.nlm.nih.gov/pmc/articles/PMC5142118/
  44. www.sciencedirect.com www.sciencedirect.com
    FAF1 Regulates Antiviral Immunity by Inhibiting MAVS but Is Antagonized by Phosphorylation upon Viral Infection
    1
    1. scibot 09 Aug 2021
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      DOI: 10.1016/j.chom.2018.10.006

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    sciencedirect.com/science/article/pii/S1931312818305444
  45. Jul 2021
  46. www.sciencedirect.com www.sciencedirect.com
    Ipa1 Is an RNA Polymerase II Elongation Factor that Facilitates Termination by Maintaining Levels of the Poly(A) Site Endonuclease Ysh1
    1
    1. scibot 28 Jul 2021
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      DOI: 10.1016/j.celrep.2019.01.051

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    sciencedirect.com/science/article/pii/S2211124719300804
  47. www.sciencedirect.com www.sciencedirect.com
    Neuroendocrine Coordination of Mitochondrial Stress Signaling and Proteostasis
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    1. scibot 27 Jul 2021
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      DOI: 10.1016/j.cell.2016.08.042

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    2. scibot 27 Jul 2021
      AB_449644

      DOI: 10.1016/j.cell.2016.08.042

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    sciencedirect.com/science/article/pii/S0092867416311394
  48. www.sciencedirect.com www.sciencedirect.com
    The histone chaperone HIR maintains chromatin states to control nitrogen assimilation and fungal virulence
    1
    1. scibot 22 Jul 2021
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      DOI: 10.1016/j.celrep.2021.109406

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    sciencedirect.com/science/article/pii/S2211124721008196
  49. May 2021
  50. www.sciencedirect.com www.sciencedirect.com
    SUCLA2-coupled regulation of GLS succinylation and activity counteracts oxidative stress in tumor cells
    1
    1. scibot 15 May 2021
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      DOI: 10.1016/j.molcel.2021.04.002

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    sciencedirect.com/science/article/pii/S1097276521002690
  51. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Aging‐associated genes and let‐7 microRNAs: a contribution to myogenic program dysregulation in oculopharyngeal muscular dystrophy
    1
    1. scibot 09 May 2021
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      DOI: 10.1096/fj.201801577RR

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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.201801577RR
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Toll receptors remodel epithelia by directing planar-polarized Src and PI3K activity
    1
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      DOI: 10.1016/j.devcel.2021.04.012

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    ncbi.nlm.nih.gov/pmc/articles/PMC8570296/
  53. Apr 2021
  54. www.sciencedirect.com www.sciencedirect.com
    cGAS phase separation inhibits TREX1-mediated DNA degradation and enhances cytosolic DNA sensing
    1
    1. scibot 12 Apr 2021
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      DOI: 10.1016/j.molcel.2021.01.024

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    sciencedirect.com/science/article/pii/S1097276521000447
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Enhanced insulin signalling ameliorates C9orf72 hexanucleotide repeat expansion toxicity in Drosophila
    1
    1. scibot 02 Apr 2021
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      DOI: 10.7554/eLife.58565

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    ncbi.nlm.nih.gov/pmc/articles/PMC8007214/
  56. Mar 2021
  57. www.sciencedirect.com www.sciencedirect.com
    ER-directed TREX1 limits cGAS activation at micronuclei
    1
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      DOI: 10.1016/j.molcel.2020.12.037

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    sciencedirect.com/science/article/pii/S1097276520309588
  58. Jan 2021
  59. link.springer.com link.springer.com
    Genetic dissection of the mitochondrial lipoylation pathway in yeast
    1
    1. scibot 28 Jan 2021
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      DOI: 10.1186/s12915-021-00951-3

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    link.springer.com/article/10.1186/s12915-021-00951-3
  60. Nov 2020
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Atg43 tethers isolation membranes to mitochondria to promote starvation-induced mitophagy in fission yeast
    1
    1. scibot 12 Nov 2020
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      DOI: 10.7554/eLife.61245

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    ncbi.nlm.nih.gov/pmc/articles/PMC7609059/
  62. Oct 2020
  63. onlinelibrary.wiley.com onlinelibrary.wiley.com
    CD200‐CD200R1 signaling pathway regulates neuroinflammation after stroke
    1
    1. scibot 22 Oct 2020
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      DOI: 10.1002/brb3.1882

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    onlinelibrary.wiley.com/doi/10.1002/brb3.1882
  64. link.springer.com link.springer.com
    Plasma Leptin Reflects Progression of Neurofibrillary Pathology in Animal Model of Tauopathy
    1
    1. scibot 02 Oct 2020
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      DOI: 10.1007/s10571-020-00972-6

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  65. Sep 2020
  66. elifesciences.org elifesciences.org
    Stress-activated MAPK signaling controls fission yeast actomyosin ring integrity by modulating formin For3 levels
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      DOI: 10.7554/eLife.57951

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  67. www.sciencedirect.com www.sciencedirect.com
    Acetylation-Dependent Deubiquitinase OTUD3 Controls MAVS Activation in Innate Antiviral Immunity
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      DOI: 10.1016/j.molcel.2020.06.020

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  68. www.sciencedirect.com www.sciencedirect.com
    Partial Inhibition of RNA Polymerase I Promotes Animal Health and Longevity
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      DOI: 10.1016/j.celrep.2020.01.017

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  69. www.sciencedirect.com www.sciencedirect.com
    Bab2 Functions as an Ecdysone-Responsive Transcriptional Repressor during Drosophila Development
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      DOI: 10.1016/j.celrep.2020.107972

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  70. www.sciencedirect.com www.sciencedirect.com
    A Translocation Pathway for Vesicle-Mediated Unconventional Protein Secretion
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      DOI: 10.1016/j.cell.2020.03.031

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  71. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Impact of long‐lasting spontaneous physical activity on bone morphogenetic protein 4 in the heart and tibia in murine model of heart failure
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      DOI: 10.14814/phy2.14412

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  72. www.sciencedirect.com www.sciencedirect.com
    Sugar-Induced Obesity and Insulin Resistance Are Uncoupled from Shortened Survival in Drosophila
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      DOI: 10.1016/j.cmet.2020.02.016

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  73. www.sciencedirect.com www.sciencedirect.com
    Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains
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      DOI: 10.1016/j.celrep.2020.108050

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  74. Jan 2020
  75. www.sciencedirect.com www.sciencedirect.com
    Miro1 Marks Parkinson’s Disease Subset and Miro1 Reducer Rescues Neuron Loss in Parkinson’s Models
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      DOI: 10.1016/j.cmet.2019.08.023

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  76. www.nature.com www.nature.com
    Rif1 S- acylation mediates DNA double-strand break repair at the inner nuclear membrane
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      DOI: 10.1038/s41467-019-10349-z

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  77. www.sciencedirect.com www.sciencedirect.com
    Mutual Zonated Interactions of Wnt and Hh Signaling Are Orchestrating the Metabolism of the Adult Liver in Mice and Human
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      DOI: 10.1016/j.celrep.2019.11.104

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    Influenza Virus Exploits an Interferon-Independent lncRNA to Preserve Viral RNA Synthesis through Stabilizing Viral RNA Polymerase PB1
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      DOI: 10.1016/j.celrep.2019.05.036

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    sciencedirect.com/science/article/pii/S2211124719306564
  79. www.sciencedirect.com www.sciencedirect.com
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      DOI: 10.1016/j.celrep.2019.03.027

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    sciencedirect.com/science/article/pii/S2211124719303432
  80. www.sciencedirect.com www.sciencedirect.com
    Ipa1 Is an RNA Polymerase II Elongation Factor that Facilitates Termination by Maintaining Levels of the Poly(A) Site Endonuclease Ysh1
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      AB_449644

      DOI: 10.1016/j.celrep.2019.01.051

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  81. journals.plos.org journals.plos.org
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      DOI: 10.1371/journal.pbio.2006094

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    journals.plos.org/plosbiology/article
  82. Nov 2018
  83. www.sciencedirect.com www.sciencedirect.com
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    sciencedirect.com/science/article/pii/S1931312818304906
  84. www.sciencedirect.com www.sciencedirect.com
    Species-Specific Deamidation of cGAS by Herpes Simplex Virus UL37 Protein Facilitates Viral Replication
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    sciencedirect.com/science/article/pii/S1931312818303743
  85. www.sciencedirect.com www.sciencedirect.com
    Conserved Lipid and Small-Molecule Modulation of COQ8 Reveals Regulation of the Ancient Kinase-like UbiB Family
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    sciencedirect.com/science/article/pii/S2451945617303963
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Validation of a yeast malate dehydrogenase 2 (Mdh2) antibody tested for use in western blots
    1
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      AB_449644

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  87. www.sciencedirect.com www.sciencedirect.com
    E2F/DP Prevents Cell-Cycle Progression in Endocycling Fat Body Cells by Suppressing dATM Expression
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  88. www.sciencedirect.com www.sciencedirect.com
    Regulation of Androgen Receptor Activity by Transient Interactions of Its Transactivation Domain with General Transcription Regulators
    1
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    sciencedirect.com/science/article/pii/S096921261730360X
  89. www.sciencedirect.com www.sciencedirect.com
    Multi-omics Reveal Specific Targets of the RNA-Binding Protein Puf3p and Its Orchestration of Mitochondrial Biogenesis
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    sciencedirect.com/science/article/pii/S2405471217305409
  90. Nov 2017
  91. www.sciencedirect.com www.sciencedirect.com
    A Tubulin Binding Switch Underlies Kip3/Kinesin-8 Depolymerase Activity
    1
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      Curator: @chewbeccax

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  92. www.sciencedirect.com www.sciencedirect.com
    Histone Mutants Separate R Loop Formation from Genome Instability Induction
    1
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    sciencedirect.com/science/article/pii/S1097276517303532
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transgenerational programming of longevity through E(z)-mediated histone H3K27 trimethylation in Drosophila
    1
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      mouse monoclonal anti-beta actin antibody (ab8224, Abcam)

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    ncbi.nlm.nih.gov/pmc/articles/PMC5191882/
  94. www.sciencedirect.com www.sciencedirect.com
    The Ubiquitin Ligase CHIP Integrates Proteostasis and Aging by Regulation of Insulin Receptor Turnover
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    sciencedirect.com/science/article/pii/S0092867417304154
  95. www.sciencedirect.com www.sciencedirect.com
    Spt5 Plays Vital Roles in the Control of Sense and Antisense Transcription Elongation
    1
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      AB_449644

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  96. elifesciences.org elifesciences.org
    The fail-safe mechanism of post-transcriptional silencing of unspliced HAC1 mRNA
    1
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      AB_449644

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    elifesciences.org/articles/20069
  97. www.sciencedirect.com www.sciencedirect.com
    MECR Mutations Cause Childhood-Onset Dystonia and Optic Atrophy, a Mitochondrial Fatty Acid Synthesis Disorder
    1
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      AB_449644

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    sciencedirect.com/science/article/pii/S0002929716304347
  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of SynDIG1 Reduces Excitatory Synapse Maturation But Not Formation In Vivo
    1
    1. scibot 08 Nov 2017
      AB_449644

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