Hypothesis

127 Matching Annotations

Jul 2025
52.53.155.43 52.53.155.43

ssrn-5353044-html.html

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1. scibot 25 Jul 2025
  
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  DOI: 10.2139/ssrn.5353044
  
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52.53.155.43/6f055e2327548a4d44d1455e8cde232efc1eedcd/ssrn-5353044-html.html
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Matrix Stiffness Regulates TGFβ1‐Induced αSMA Expression via a G9a‐LATS‐YAP Signaling Cascade

1
1. scibot 16 Jul 2025
  
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  DOI: 10.1096/fba.2025-00117
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12256985/
Jun 2025
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CXCR4-LASP1-G9a-SNAIL axis drives NEPC transdifferentiation via induction of EMT and downregulation of REST

1
1. scibot 11 Jun 2025
  
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  DOI: 10.1016/j.xgen.2025.100916
  
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sciencedirect.com/science/article/pii/S2666979X25001727
May 2025
www.cell.com www.cell.com

The nucleolar granular component mediates genome-nucleolus interactions and establishes their repressive chromatin states

1
1. scibot 29 May 2025
  
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  DOI: 10.1016/j.molcel.2025.05.004
  
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cell.com/molecular-cell/fulltext/S1097-2765(25)00409-5
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KDM3A and KDM3B regulate alternative splicing in mouse pluripotent stem cells

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1. scibot 29 May 2025
  
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  DOI: 10.1016/j.isci.2025.112612
  
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sciencedirect.com/science/article/pii/S2589004225008739
Apr 2025
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The establishment of nuclear organization in mouse embryos is orchestrated by multiple epigenetic pathways

1
1. scibot 24 Apr 2025
  
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  DOI: 10.1016/j.cell.2025.03.044
  
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sciencedirect.com/science/article/pii/S0092867425003964
Dec 2024
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Actin-based deformations of the nucleus control mouse multiciliated ependymal cell differentiation

1
1. scibot 12 Dec 2024
  
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  DOI: 10.1016/j.devcel.2024.11.008
  
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sciencedirect.com/science/article/pii/S1534580724006737
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DNA hypomethylation promotes UHRF1-and SUV39H1/H2-dependent crosstalk between H3K18ub and H3K9me3 to reinforce heterochromatin states

1
1. scibot 05 Dec 2024
  
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  RRID:AB_449854
  
  DOI: 10.1016/j.molcel.2024.11.009
  
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sciencedirect.com/science/article/pii/S1097276524009146
Nov 2024
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EMF1 functions as a 3D chromatin modulator in Arabidopsis

1
1. scibot 24 Nov 2024
  
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  DOI: 10.1016/j.molcel.2024.10.031
  
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sciencedirect.com/science/article/pii/S1097276524008712
Oct 2024
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Selective translation of nuclear mitochondrial respiratory proteins reprograms succinate metabolism in AML development and chemoresistance

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1. scibot 02 Oct 2024
  
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  DOI: 10.1016/j.stem.2024.09.008
  
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sciencedirect.com/science/article/pii/S1934590924003229
Aug 2024
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Mapping the dynamics of epigenetic adaptation in S. pombe during heterochromatin misregulation

1
1. scibot 18 Aug 2024
  
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  DOI: 10.1016/j.devcel.2024.07.006
  
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sciencedirect.com/science/article/pii/S1534580724004441
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A replisome-associated histone H3-H4 chaperone required for epigenetic inheritance

1
1. scibot 18 Aug 2024
  
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  DOI: 10.1016/j.cell.2024.07.006
  
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sciencedirect.com/science/article/pii/S0092867424007669
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The fork protection complex promotes parental histone recycling and epigenetic memory

1
1. scibot 18 Aug 2024
  
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  DOI: 10.1016/j.cell.2024.07.017
  
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sciencedirect.com/science/article/pii/S0092867424007773
Jul 2024
pathsocjournals.onlinelibrary.wiley.com pathsocjournals.onlinelibrary.wiley.com

Histone demethylase PHF8 promotes prostate cancer metastasis via the E2F1–SNAI1 axis

1
1. scibot 23 Jul 2024
  
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  RRID:AB_449854
  
  DOI: 10.1002/path.6325
  
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pathsocjournals.onlinelibrary.wiley.com/doi/full/10.1002/path.6325
May 2024
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RNA quality control factors nucleate Clr4/SUV39H and trigger constitutive heterochromatin assembly

1
1. scibot 30 May 2024
  
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  DOI: 10.1016/j.cell.2024.04.042
  
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sciencedirect.com/science/article/pii/S0092867424004689
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Heterochromatic 3D genome organization is directed by HP1a- and H3K9-dependent and independent mechanisms

1
1. scibot 30 May 2024
  
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  AB_449854
  
  DOI: 10.1016/j.molcel.2024.05.002
  
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sciencedirect.com/science/article/pii/S1097276524003952
Jan 2024
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PCGF6 controls murine Tuft cell differentiation via H3K9me2 modification independently of Polycomb repression

1
1. scibot 19 Jan 2024
  
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  RRID:AB_449854
  
  DOI: 10.1016/j.devcel.2023.12.015
  
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sciencedirect.com/science/article/pii/S1534580723006962
Dec 2023
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TOR inactivation triggers heterochromatin formation in rDNA during glucose starvation

1
1. scibot 02 Dec 2023
  
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  RRID:AB_449854
  
  DOI: 10.1016/j.celrep.2023.113320
  
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sciencedirect.com/science/article/pii/S2211124723013323
Oct 2023
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Three-dimensional genome architecture coordinates key regulators of lineage specification in mammary epithelial cells

1
1. scibot 27 Oct 2023
  
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  DOI: 10.1016/j.xgen.2023.100424
  
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sciencedirect.com/science/article/pii/S2666979X23002501
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Exposure to high-sugar diet induces transgenerational changes in sweet sensitivity and feeding behavior via H3K27me3 reprogramming

1
1. scibot 09 Oct 2023
  
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  DOI: 10.7554/eLife.85365
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10558205/
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Epigenetic balance ensures mechanistic control of MLL amplification and rearrangement

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1. scibot 06 Oct 2023
  
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  DOI: 10.1016/j.cell.2023.09.009
  
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sciencedirect.com/science/article/pii/S0092867423010280
Sep 2023
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Perturbations in 3D genome organization can promote acquired drug resistance

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1. scibot 30 Sep 2023
  
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  DOI: 10.1016/j.celrep.2023.113124
  
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sciencedirect.com/science/article/pii/S2211124723011361
Aug 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Histone variants shape chromatin states in Arabidopsis

1
1. scibot 03 Aug 2023
  
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  DOI: 10.7554/eLife.87714
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10393023/
Jul 2023
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TONSOKU is required for the maintenance of repressive chromatin modifications in Arabidopsis

1
1. scibot 04 Jul 2023
  
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  RRID:AB_449854
  
  DOI: 10.1016/j.celrep.2023.112738
  
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sciencedirect.com/science/article/pii/S2211124723007490
Jun 2023
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Oncogenic IDH mutations increase heterochromatin-related replication stress without impacting homologous recombination

1
1. scibot 16 Jun 2023
  
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  DOI: 10.1016/j.molcel.2023.05.026
  
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sciencedirect.com/science/article/pii/S1097276523003829
May 2023
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Site-specific R-loops induce CGG repeat contraction and fragile X gene reactivation

1
1. scibot 20 May 2023
  
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  DOI: 10.1016/j.cell.2023.04.035
  
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sciencedirect.com/science/article/pii/S0092867423004695
www.nature.com www.nature.com

Methionine consumption by cancer cells drives a progressive upregulation of PD-1 expression in CD4 T cells

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1. scibot 06 May 2023
  
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  DOI: 10.1038/s41467-023-38316-9
  
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nature.com/articles/s41467-023-38316-9
Mar 2023
www.biorxiv.org www.biorxiv.org

Exposure to high-sugar diet induces transgenerational changes in sweet sensitivity and feeding behavior via H3K27me3 reprogramming

1
1. scibot 08 Mar 2023
  
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  DOI: 10.1101/2023.01.15.524137
  
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biorxiv.org/content/10.1101/2023.01.15.524137v1
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JMJ28 guides sequence-specific targeting of ATX1/2-containing COMPASS-like complex in Arabidopsis

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1. scibot 03 Mar 2023
  
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  DOI: 10.1016/j.celrep.2023.112163
  
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sciencedirect.com/science/article/pii/S2211124723001742
Jan 2023
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Specification of human germ cell fate with enhanced progression capability supported by hindgut organoids

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1. scibot 28 Jan 2023
  
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  DOI: 10.1016/j.celrep.2022.111907
  
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sciencedirect.com/science/article/pii/S221112472201806X
Dec 2022
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Hypoxia induces transgenerational epigenetic inheritance of small RNAs

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1. scibot 18 Dec 2022
  
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  DOI: 10.1016/j.celrep.2022.111800
  
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sciencedirect.com/science/article/pii/S2211124722016886
Sep 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Cholinergic REST-G9a gene repression through HMGB1-TLR4 neuroimmune signaling regulates basal forebrain cholinergic neuron phenotype

1
1. scibot 08 Sep 2022
  
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  DOI: 10.3389/fnmol.2022.992627
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9441808/
Aug 2022
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The RNA helicase DDX5 cooperates with EHMT2 to sustain alveolar rhabdomyosarcoma growth

1
1. scibot 31 Aug 2022
  
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  DOI: 10.1016/j.celrep.2022.111267
  
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sciencedirect.com/science/article/pii/S2211124722010853
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Single-chromosome fission yeast models reveal the configuration robustness of a functional genome

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1. scibot 26 Aug 2022
  
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  DOI: 10.1016/j.celrep.2022.111237
  
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sciencedirect.com/science/article/pii/S2211124722010543
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A stress-blinded Atf1 can fully assemble heterochromatin in a RNAi-independent minimal mat locus but impairs directionality of mat2/3 switching

1
1. scibot 12 Aug 2022
  
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  DOI: 10.1016/j.isci.2022.104820
  
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sciencedirect.com/science/article/pii/S2589004222010926
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Repeat-based holocentromeres influence genome architecture and karyotype evolution

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1. scibot 06 Aug 2022
  
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  DOI: 10.1016/j.cell.2022.06.045
  
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sciencedirect.com/science/article/pii/S0092867422007978
Jun 2022
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Counteracting chromatin effects of a splicing-correcting antisense oligonucleotide improves its therapeutic efficacy in spinal muscular atrophy

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1. scibot 10 Jun 2022
  
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A cell-sorting-based protocol for cell cycle small-scale ChIP sequencing

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  DOI: 10.1016/j.xpro.2022.101243
  
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Feb 2022
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Histone marks regulate the epithelial-to-mesenchymal transition via alternative splicing

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Activation-induced chromatin reorganization in neurons depends on HDAC1 activity

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Histone H1 prevents non-CG methylation-mediated small RNA biogenesis in Arabidopsis heterochromatin

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Chemical-induced chromatin remodeling reprograms mouse ESCs to totipotent-like stem cells

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Dynamic chromatin state profiling reveals regulatory roles of auxin and cytokinin in shoot regeneration

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SUMOylation of linker histone H1 drives chromatin condensation and restriction of embryonic cell fate identity

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Fasting-mimicking diet blocks triple-negative breast cancer and cancer stem cell escape

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The histone chaperone FACT facilitates heterochromatin spreading by regulating histone turnover and H3K9 methylation states

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Gene bookmarking by the heat shock transcription factor programs the insulin-like signaling pathway

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Tracing the emergence of primordial germ cells from bilaminar disc rabbit embryos and pluripotent stem cells

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Collective regulation of chromatin modifications predicts replication timing during cell cycle

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SMAR1 Suppresses the Cancer Stem Cell Population via hTERT Repression in Colorectal Cancer Cells

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Aging-Dependent Downregulation of SUV39H1 Histone Methyltransferase Increases Susceptibility to Stress-Induced Depressive Behavior

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  DOI: 10.1007/s12035-021-02529-0
  
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The prolyl-isomerase PIN1 is essential for nuclear Lamin-B structure and function and protects heterochromatin under mechanical stress

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Epigenetic Dysregulation Induces Translocation of Histone H3 into Cytoplasm

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  DOI: 10.1002/advs.202100779
  
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Multi-omic Profiling Reveals Dynamics of the Phased Progression of Pluripotency

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  DOI: 10.1242/dev.151134
  
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Untitled document

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Chromatin Modifiers SET-25 and SET-32 Are Required for Establishment but Not Long-Term Maintenance of Transgenerational Epigenetic Inheritance

1
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Multiomics analyses reveal a critical role of selenium in controlling T cell differentiation in Crohn’s disease

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Untitled document

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Targeting CDK9 Reactivates Epigenetically Silenced Genes in Cancer

1
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A Lamina-Associated Domain Border Governs Nuclear Lamina Interactions, Transcription, and Recombination of the Tcrb Locus

1
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Multi-omic Profiling Reveals Dynamics of the Phased Progression of Pluripotency

1
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Chromatin Modifiers SET-25 and SET-32 Are Required for Establishment but Not Long-Term Maintenance of Transgenerational Epigenetic Inheritance

1
1. scibot 28 Jul 2021
  
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Depletion of HP1α alters the mechanical properties of MCF7 nuclei

1
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  DOI: 10.1016/j.bpj.2021.05.017
  
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The histone methyltransferase G9a mediates stress-regulated alcohol drinking

1
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  DOI: 10.1111/adb.13060
  
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HDAC1 SUMOylation promotes Argonaute-directed transcriptional silencing in C. elegans

1
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  DOI: 10.7554/eLife.63299
  
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Repression of endogenous retroviruses prevents antiviral immune response and is required for mammary gland development

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  DOI: 10.1016/j.stem.2021.04.030
  
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GATA6 defines endoderm fate by controlling chromatin accessibility during differentiation of human-induced pluripotent stem cells

1
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  DOI: 10.1016/j.celrep.2021.109145
  
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Pathogenic LMNA variants disrupt cardiac lamina-chromatin interactions and de-repress alternative fate genes

1
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  DOI: 10.1016/j.stem.2020.12.016
  
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PIWI proteomics identifies Atari and Pasilla as piRNA biogenesis factors in Aedes mosquitoes

1
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  DOI: 10.1016/j.celrep.2021.109073
  
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The chromatin-remodeling protein BAF60/SWP73A regulates the plant immune receptor NLRs

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Aging increases vulnerability to stress-induced depression via upregulation of NADPH oxidase in mice

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Epigenetic regulation of Wnt7b expression by the cis-acting long noncoding RNA Lnc-Rewind in muscle stem cells

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The Essential Function of SETDB1 in Homologous Chromosome Pairing and Synapsis during Meiosis

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Unexpected Transcriptional Programs Contribute to Hippocampal Memory Deficits and Neuronal Stunting after Early-Life Adversity

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G9a Promotes Breast Cancer Recurrence through Repression of a Pro-inflammatory Program

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G9a Plays Distinct Roles in Maintaining DNA Methylation, Retrotransposon Silencing, and Chromatin Looping

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A Synthetic Approach to Reconstruct the Evolutionary and Functional Innovations of the Plant Histone Variant H2A.W

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Prdm16 Deficiency Leads to Age-Dependent Cardiac Hypertrophy, Adverse Remodeling, Mitochondrial Dysfunction, and Heart Failure

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The Histone Chaperone FACT Induces Cas9 Multi-turnover Behavior and Modifies Genome Manipulation in Human Cells

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Increased Efficacy of Histone Methyltransferase G9a Inhibitors Against MYCN-Amplified Neuroblastoma

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Evolutionary Persistence of DNA Methylation for Millions of Years after Ancient Loss of a De Novo Methyltransferase

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Repressive H3K9me2 protects lifespan against the transgenerational burden of COMPASS activity in C. elegans

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MicroRNA-137 drives epigenetic reprogramming in the adult amygdala and behavioral changes after adolescent alcohol exposure

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Dense Transposon Integration Reveals Essential Cleavage and Polyadenylation Factors Promote Heterochromatin Formation

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The Histone Methyltransferase G9a Controls Axon Growth by Targeting the RhoA Signaling Pathway

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H3K9me2 orchestrates inheritance of spatial positioning of peripheral heterochromatin through mitosis

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Branched-Chain Amino Acid Metabolic Reprogramming Orchestrates Drug Resistance to EGFR Tyrosine Kinase Inhibitors

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DNA Methylation and Histone H1 Jointly Repress Transposable Elements and Aberrant Intragenic Transcripts

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Native Chromatin Proteomics Reveals a Role for Specific Nucleoporins in Heterochromatin Organization and Maintenance

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The Chaperone FACT and Histone H2B Ubiquitination Maintain S. pombe Genome Architecture through Genic and Subtelomeric Functions

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Small-molecule targeting of oncogenic FTO demethylase in acute myeloid leukemia

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Natural depletion of histone H1 in sex cells causes DNA demethylation, heterochromatin decondensation and transposon activation

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Untitled document

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Histone H3K9 Methyltransferase G9a in Oocytes Is Essential for Preimplantation Development but Dispensable for CG Methylation Protection

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Transcriptional profiling of human neural precursors post alcohol exposure reveals impaired neurogenesis via dysregulation of ERK signaling and miR‐145

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MYC Interacts with the G9a Histone Methyltransferase to Drive Transcriptional Repression and Tumorigenesis

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Class I histone deacetylases in retinal progenitors and differentiating ganglion cells

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Short-Term Mitochondrial Permeability Transition Pore Opening Modulates Histone Lysine Methylation at the Early Phase of Somatic Cell Reprogramming

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Dppa2/4 Facilitate Epigenetic Remodeling during Reprogramming to Pluripotency

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A LINE1-Nucleolin Partnership Regulates Early Development and ESC Identity

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Arabidopsis Serrate Coordinates Histone Methyltransferases ATXR5/6 and RNA Processing Factor RDR6 to Regulate Transposon Expression

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Cross Talk between One-Carbon Metabolism, Eph Signaling, and Histone Methylation Promotes Neural Stem Cell Differentiation

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The Transcriptionally Permissive Chromatin State of Embryonic Stem Cells Is Acutely Tuned to Translational Output

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A Family of Vertebrate-Specific Polycombs Encoded by the LCOR/LCORL Genes Balance PRC2 Subtype Activities

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PKCα-LSD1-NF-κB-Signaling Cascade Is Crucial for Epigenetic Control of the Inflammatory Response

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An endosiRNA-Based Repression Mechanism Counteracts Transposon Activation during Global DNA Demethylation in Embryonic Stem Cells

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Early-Life Gene Expression in Neurons Modulates Lasting Epigenetic States

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SNF2 Family Protein Fft3 Suppresses Nucleosome Turnover to Promote Epigenetic Inheritance and Proper Replication

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Dynamic Control of X Chromosome Conformation and Repression by a Histone H4K20 Demethylase

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Myc Regulates Chromatin Decompaction and Nuclear Architecture during B Cell Activation

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Loss of TET1 facilitates DLD1 colon cancer cell migration via H3K27me3‐mediated down‐regulation of E‐cadherin

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Glucose Sensing by Skeletal Myocytes Couples Nutrient Signaling to Systemic Homeostasis

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Bromodomain Protein BRD4 Is a Transcriptional Repressor of Autophagy and Lysosomal Function

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Cav1.2 channels mediate persistent chronic stress-induced behavioral deficits that are associated with prefrontal cortex activation of the p25/Cdk5-glucocorticoid receptor pathway

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Registered report: Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases

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  Mouse monoclonal anti-H3K9me2
  
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