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Muscle satellite cell editing by LNP-CRISPR-Cas9 to resist muscle injury

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1. scibot 23 Dec 2025
  
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  DOI: 10.1016/j.celrep.2025.116695
  
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sciencedirect.com/science/article/pii/S2211124725014676
Dec 2025
54.241.53.176 54.241.53.176

1-s2.0-S2589004225026197-main-html.html

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1. scibot 09 Dec 2025
  
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  DOI: 10.1016/j.isci.2025.114358
  
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54.241.53.176/ccfdaea90d00d1e2ad4294448fdfaf1320c55233/1-s2.0-S2589004225026197-main-html.html
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Restricting lipid accumulation in tumor-infiltrating neutrophils mediates caloric restriction-induced anti-cancer effects

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1. scibot 09 Dec 2025
  
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  DOI: 10.1016/j.cmet.2025.11.007
  
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sciencedirect.com:5037/science/article/pii/S1550413125004917
Oct 2025
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TLR ligand sensing by lymph node FRCs directs intranodal lymphocyte accumulation to promote immune responses

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1. scibot 29 Oct 2025
  
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  DOI: 10.1016/j.isci.2025.113734
  
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sciencedirect.com/science/article/pii/S2589004225019959
Sep 2025
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Gut microbe-derived metabolites drive psoriatic inflammation via modulation of skin Th17 cells

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1. scibot 11 Sep 2025
  
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  DOI: 10.1016/j.immuni.2025.08.006
  
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sciencedirect.com/science/article/pii/S1074761325003693
Aug 2025
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Mutations in MLL3 promote breast cancer progression via HIF1α-dependent intratumoral recruitment and differentiation of regulatory T cells

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1. scibot 01 Aug 2025
  
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  DOI: 10.1016/j.immuni.2025.07.008
  
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sciencedirect.com/science/article/pii/S1074761325003176
Jul 2025
52.53.155.43 52.53.155.43

2025.07.10.664251v1.full-html.html

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1. scibot 22 Jul 2025
  
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  DOI: 10.1101/2025.07.10.664251
  
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52.53.155.43/1cfa6b550b40cdda3522311aa4275c22b0c379c4/2025.07.10.664251v1.full-html.html
Jun 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Proliferating Microglia Exhibit Unique Transcriptional and Functional Alterations in Alzheimer’s Disease

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1. scibot 11 Jun 2025
  
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  DOI: 10.1080/17590914.2025.2506406
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12140498/
May 2025
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PUS10-induced tRNA fragmentation impacts retrotransposon-driven inflammation

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1. scibot 22 May 2025
  
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  DOI: 10.1016/j.celrep.2025.115735
  
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sciencedirect.com/science/article/pii/S2211124725005066
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Arrestin-biased allosteric modulator of neurotensin receptor 1 alleviates acute and chronic pain

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1. scibot 20 May 2025
  
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  DOI: 10.1016/j.cell.2025.04.038
  
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sciencedirect.com/science/article/pii/S0092867425005082
Apr 2025
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Engineering TCR-controlled fuzzy logic into CAR T cells enhances therapeutic specificity

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1. scibot 15 Apr 2025
  
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  DOI: 10.1016/j.cell.2025.03.017
  
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sciencedirect.com/science/article/pii/S0092867425002909
Feb 2025
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Sweetener aspartame aggravates atherosclerosis through insulin-triggered inflammation

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1. scibot 20 Feb 2025
  
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  DOI: 10.1016/j.cmet.2025.01.006
  
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sciencedirect.com/science/article/pii/S1550413125000063
Dec 2024
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Elevated IL-22 as a result of stress-induced gut leakage suppresses septal neuron activation to ameliorate anxiety-like behavior

1
1. scibot 10 Dec 2024
  
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  DOI: 10.1016/j.immuni.2024.11.008
  
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sciencedirect.com/science/article/pii/S1074761324005235
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Vimentin modulates regulatory T cell receptor-ligand interactions at distal pole complex, leading to dysregulated host response to viral pneumonia

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1. scibot 10 Dec 2024
  
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  DOI: 10.1016/j.celrep.2024.115056
  
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sciencedirect.com/science/article/pii/S2211124724014074
Jul 2024
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Inhibition of SIRT1 relieves hepatocarcinogenesis via alleviating autophagy and inflammation

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1. scibot 30 Jul 2024
  
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  DOI: 10.1016/j.ijbiomac.2024.134120
  
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sciencedirect.com/science/article/pii/S0141813024049250
dx.doi.org dx.doi.org

Cenicriviroc Suppresses and Reverses Steatohepatitis by Regulating Macrophage Infiltration and M2 Polarization in Mice

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1. scibot 18 Jul 2024
  
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  DOI: 10.1210/endocr/bqae069
  
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dx.doi.org/10.1210/endocr/bqae069
Jun 2024
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Myocardial infarction accelerates the progression of MASH by triggering immunoinflammatory response and induction of periosti

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1. scibot 05 Jun 2024
  
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  DOI: 10.1016/j.cmet.2024.04.020
  
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sciencedirect.com/science/article/pii/S1550413124001761
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Blockage of L2HGDH-mediated S-2HG catabolism orchestrates macrophage polarization to elicit antitumor immunity

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1. scibot 04 Jun 2024
  
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  DOI: 10.1016/j.celrep.2024.114300
  
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sciencedirect.com/science/article/pii/S2211124724006284
Apr 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

CRISPR-Cas9 screening identifies INTS3 as an anti-apoptotic RNA-binding protein and therapeutic target for colorectal cancer

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1. scibot 28 Apr 2024
  
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  DOI: 10.1016/j.isci.2024.109676
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11043890/
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Regulation of muscle hypertrophy through granulin: Relayed communication among mesenchymal progenitors, macrophages, and satellite cells

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1. scibot 05 Apr 2024
  
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  DOI: 10.1016/j.celrep.2024.114052
  
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sciencedirect.com/science/article/pii/S2211124724003802
Feb 2024
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Lactate modulates RNA splicing to promote CTLA-4 expression in tumor-infiltrating regulatory T cells

2
1. scibot 29 Feb 2024
  
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  DOI: 10.1016/j.immuni.2024.01.019
  
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  DOI: 10.1016/j.immuni.2024.01.019
  
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sciencedirect.com/science/article/pii/S1074761324000451
Jan 2024
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Bispecific dendritic-T cell engager potentiates anti-tumor immunity

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1. scibot 19 Jan 2024
  
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  DOI: 10.1016/j.cell.2023.12.011
  
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sciencedirect.com/science/article/pii/S0092867423013430
Dec 2023
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A gut-restricted glutamate carboxypeptidase II inhibitor reduces monocytic inflammation and improves preclinical colitis

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1. scibot 02 Dec 2023
  
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  DOI: 10.1126/scitranslmed.abn7491
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10661206/
Oct 2023
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Spatial-temporal proliferation of hepatocytes during pregnancy revealed by genetic lineage tracing

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1. scibot 14 Oct 2023
  
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  DOI: 10.1016/j.stem.2023.09.002
  
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sciencedirect.com/science/article/pii/S1934590923003235
Jul 2023
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PLA2G2E-mediated lipid metabolism triggers brain-autonomous neural repair after ischemic stroke

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1. scibot 27 Jul 2023
  
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  DOI: 10.1016/j.neuron.2023.06.024
  
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sciencedirect.com/science/article/abs/pii/S089662732300483X
Jun 2023
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PD-L1/PD-1 checkpoint pathway regulates hippocampal neuronal excitability and learning and memory behavior

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1. scibot 22 Jun 2023
  
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  DOI: 10.1016/j.neuron.2023.05.022
  
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sciencedirect.com/science/article/pii/S0896627323003951
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MicroRNA-223 limits murine hemogenic endothelial cell specification and myelopoiesis

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1. scibot 09 Jun 2023
  
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  DOI: 10.1016/j.devcel.2023.05.007
  
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sciencedirect.com/science/article/pii/S153458072300240X
Apr 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

IRE1α drives lung epithelial progenitor dysfunction to establish a niche for pulmonary fibrosis

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1. scibot 04 Apr 2023
  
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  DOI: 10.1152/ajplung.00408.2021
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8957349/
Mar 2023
europepmc.org europepmc.org

Epigenetic dosage identifies two major and functionally distinct β cell subtypes

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1. scibot 28 Mar 2023
  
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  DOI: 10.1016/j.cmet.2023.03.008
  
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europepmc.org/article/med/36948185
Feb 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Adipocyte-Secreted IL-6 Sensitizes Macrophages to IL-4 Signaling

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1. scibot 23 Feb 2023
  
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  DOI: 10.2337/db22-0444
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9935493/
Sep 2022
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Ablation of the endoplasmic reticulum stress kinase PERK induces paraptosis and type I interferon to promote anti-tumor T cell responses

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1. scibot 24 Sep 2022
  
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  DOI: 10.1016/j.ccell.2022.08.016
  
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sciencedirect.com/science/article/pii/S1535610822003804
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The CD4+ T cell response to a commensal-derived epitope transitions from a tolerant to an inflammatory state in Crohn’s disease

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1. scibot 20 Sep 2022
  
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  DOI: 10.1016/j.immuni.2022.08.016
  
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sciencedirect.com/science/article/pii/S1074761322004101
Jun 2022
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PGE2-EP2/EP4 signaling elicits immunosuppression by driving the mregDC-Treg axis in inflammatory tumor microenvironment

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1. scibot 09 Jun 2022
  
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  DOI: 10.1016/j.celrep.2022.110914
  
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sciencedirect.com/science/article/pii/S221112472200691X
Apr 2022
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Isolation of macrophages from mouse skin wounds for single-cell RNA sequencing

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1. scibot 21 Apr 2022
  
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  RRID:AB_465050
  
  DOI: 10.1016/j.xpro.2022.101337
  
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sciencedirect.com/science/article/pii/S2666166722002179
Mar 2022
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Neutral ceramidase-dependent regulation of macrophage metabolism directs intestinal immune homeostasis and controls enteric infection

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  DOI: 10.1016/j.celrep.2022.110560
  
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Relayed signaling between mesenchymal progenitors and muscle stem cells ensures adaptive stem cell response to increased mechanical load

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  DOI: 10.1016/j.stem.2021.11.003
  
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sciencedirect.com/science/article/pii/S1934590921004513
Oct 2021
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Mitochondrial metabolism coordinates stage-specific repair processes in macrophages during wound healing

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  DOI: 10.1016/j.cmet.2021.10.004
  
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Sep 2021
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A20 deficiency in myeloid cells protects mice from diet-induced obesity and insulin resistance due to increased fatty acid metabolism

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  DOI: 10.1016/j.celrep.2021.109748
  
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RORα is critical for mTORC1 activity in T cell-mediated colitis

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  DOI: 10.1016/j.celrep.2021.109682
  
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Aug 2021
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ADAR1 interaction with Z-RNA promotes editing of endogenous double-stranded RNA and prevents MDA5-dependent immune activation

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  DOI: 10.1016/j.celrep.2021.109500
  
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Autophagy regulates inflammatory programmed cell death via turnover of RHIM-domain proteins

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  DOI: 10.7554/eLife.44452
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6615860/
Jul 2021
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Distinct skeletal stem cell types orchestrate long bone skeletogenesis

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  DOI: 10.7554/eLife.66063
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8289409/
May 2021
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Decreased Expression of the Host Long-Noncoding RNA-GM Facilitates Viral Escape by Inhibiting the Kinase activity TBK1 via S-glutathionylation

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  DOI: 10.1016/j.immuni.2020.11.010
  
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Apr 2021
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Targeting Mitochondria-Located circRNA SCAR Alleviates NASH via Reducing mROS Output

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1. scibot 24 Apr 2021
  
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  DOI: 10.1016/j.cell.2020.08.009
  
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Emergence of a High-Plasticity Cell State during Lung Cancer Evolution

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  DOI: 10.1016/j.ccell.2020.06.012
  
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cell.com/cancer-cell/fulltext/S1535-6108(20)30316-0
Sep 2020
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SPHK2-Generated S1P in CD11b+ Macrophages Blocks STING to Suppress the Inflammatory Function of Alveolar Macrophages

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  DOI: 10.1016/j.celrep.2020.02.112
  
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Jan 2020
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The CalcR-PKA-Yap1 Axis Is Critical for Maintaining Quiescence in Muscle Stem Cells

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  DOI: 10.1016/j.celrep.2019.10.057
  
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Sphingosine-1-Phosphate Receptor 1 Activity Promotes Tumor Growth by Amplifying VEGF-VEGFR2 Angiogenic Signaling

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  DOI: 10.1016/j.celrep.2019.11.036
  
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Age-Related Dopaminergic Innervation Augments T Helper 2-Type Allergic Inflammation in the Postnatal Lung

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  DOI: 10.1016/j.immuni.2019.10.002
  
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Sustained expression of HeyL is critical for the proliferation of muscle stem cells in overloaded muscle

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  DOI: 10.7554/eLife.48284
  
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A Subset of Type I Conventional Dendritic Cells Controls Cutaneous Bacterial Infections through VEGFα-Mediated Recruitment of Neutrophils

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  DOI: 10.1016/j.immuni.2019.03.001
  
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Untitled document

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  DOI: 10.1016/j.celrep.2019.02.101
  
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IGF-2 Preprograms Maturing Macrophages to Acquire Oxidative Phosphorylation-Dependent Anti-inflammatory Properties

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  DOI: 10.1016/j.cmet.2019.01.006
  
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sciencedirect.com/science/article/pii/S1550413119300063
Nov 2018
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Gain-of-Function Mutation of Card14 Leads to Spontaneous Psoriasis-like Skin Inflammation through Enhanced Keratinocyte Response to IL-17A

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sciencedirect.com/science/article/pii/S1074761318302504