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Regionally mapped astrocytic responses to cortical and white matter stroke show differential roles in astrocyte-induced vascular remodeling

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  DOI: 10.1016/j.neuron.2025.09.023
  
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sciencedirect.com/science/article/pii/S0896627325007111
Aug 2025
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CHI3L3+ immature neutrophils inhibit anti-tumor immunity and impede immune checkpoint blockade therapy in bone metastases

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  DOI: 10.1016/j.ccell.2025.07.007
  
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sciencedirect.com/science/article/pii/S1535610825003137
May 2025
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Foxp3 confers long-term efficacy of chimeric antigen receptor-T cells via metabolic reprogramming

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  DOI: 10.1016/j.cmet.2025.04.008
  
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Bone metastases diminish extraosseous response to checkpoint blockade immunotherapy through osteopontin-producing osteoclasts

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  DOI: 10.1016/j.ccell.2025.03.036
  
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sciencedirect.com/science/article/pii/S1535610825001370
Apr 2025
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Intestinal estrogen receptor beta modulates the murine colon tumor immune microenvironment

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  DOI: 10.1016/j.canlet.2025.217661
  
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sciencedirect.com/science/article/pii/S0304383525002277
Feb 2025
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Nanoparticle delivery of innate immune agonists combined with senescence-inducing agents promotes T cell control of pancreatic cancer

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  DOI: 10.1126/scitranslmed.adj9366
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11811823/
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SMAD4 and KRAS Status Shape Cancer Cell-Stromal Crosstalk and Therapeutic Response in Pancreatic Cancer

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  DOI: 10.1158/0008-5472.CAN-24-2330
  
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pmc.ncbi.nlm.nih.gov/articles/PMC7617379/
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Adiponectin reduces immune checkpoint inhibitor-induced inflammation without blocking anti-tumor immunity

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  DOI: 10.1016/j.ccell.2025.01.004
  
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Jan 2025
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Complement Factor H Is an ICOS Ligand Modulating Tregs in the Glioma Microenvironment

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1. scibot 25 Jan 2025
  
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  DOI: 10.1158/2326-6066.CIR-23-1092
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11712038/
Dec 2024
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EZH2 inhibition enhances T cell immunotherapies by inducing lymphoma immunogenicity and improving T cell function

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  DOI: 10.1016/j.ccell.2024.11.006
  
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sciencedirect.com/science/article/pii/S1535610824004410
Nov 2024
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strobl-et-al-2024-jak-stat1-as-therapeutic-target-for-egfr-deficiency-associated-inflammation-and-scarring-alopecia-html.html

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52.53.155.43/586ba8b525e8da6306112d5dd7635949084313ca/strobl-et-al-2024-jak-stat1-as-therapeutic-target-for-egfr-deficiency-associated-inflammation-and-scarring-alopecia-html.html
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JAK-STAT1 as therapeutic target for EGFR deficiency-associated inflammation and scarring alopecia

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  DOI: 10.1038/s44321-024-00166-3
  
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  DOI: 10.1038/s44321-024-00166-3
  
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embopress.org/doi/10.1038/s44321-024-00166-3
Oct 2024
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CSF1/CSF1R Signaling Inhibitor Pexidartinib (PLX3397) Reprograms Tumor-Associated Macrophages and Stimulates T-cell Infiltration in the Sarcoma Microenvironment

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1. scibot 02 Oct 2024
  
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  DOI: 10.1158/1535-7163.MCT-20-0591
  
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aacrjournals.org/mct/article/20/8/1388/673303/CSF1-CSF1R-Signaling-Inhibitor-Pexidartinib
Aug 2024
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A TNF receptor 2 agonist ameliorates neuropathology and improves cognition in an Alzheimer’s disease mouse model

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1. scibot 13 Aug 2024
  
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  14–5773-82, eBioscience
  
  DOI: 10.1073/pnas.2201137119
  
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pnas.org/doi/full/10.1073/pnas.2201137119
Jul 2024
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Proteobacteria impair anti-tumor immunity in the omentum by consuming arginine

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1. scibot 18 Jul 2024
  
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  DOI: 10.1016/j.chom.2024.06.003
  
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cell.com/cell-host-microbe/abstract/S1931-3128(24)00197-5
Feb 2024
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Scarring hair follicle destruction is driven by the collapse of EGFR-protected JAK-STAT1-sensitive stem cell immune privilege

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1. scibot 23 Feb 2024
  
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  DOI: 10.1101/2023.10.11.561653
  
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52.53.155.43/96ec307650875a091f9342a8f5a3978ef308aaef/2023.10.11.561653v1.full-html.html
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THBS1+ myeloid cells expand in SLD hepatocellular carcinoma and contribute to immunosuppression and unfavorable prognosis through TREM1

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1. scibot 13 Feb 2024
  
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  DOI: 10.1016/j.celrep.2024.113773
  
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  DOI: 10.1016/j.celrep.2024.113773
  
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Amphiregulin from regulatory T cells promotes liver fibrosis and insulin resistance in non-alcoholic steatohepatitis

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1. scibot 06 Feb 2024
  
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  DOI: 10.1016/j.immuni.2024.01.009
  
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sciencedirect.com/science/article/pii/S1074761324000347
Nov 2023
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A SOX9-B7x axis safeguards dedifferentiated tumor cells from immune surveillance to drive breast cancer progression

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  DOI: 10.1016/j.devcel.2023.10.010
  
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sciencedirect.com/science/article/pii/S1534580723005518
Oct 2023
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Supplementation with a high-glucose drink stimulates anti-tumor immune responses to glioblastoma via gut microbiota modulation

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  DOI: 10.1016/j.celrep.2023.113220
  
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Aug 2023
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Genetically modified IL2 bone-marrow-derived myeloid cells reprogram the glioma immunosuppressive tumor microenvironment

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  DOI: 10.1016/j.celrep.2023.112891
  
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sciencedirect.com/science/article/pii/S2211124723009026
Jul 2023
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PARP2 downregulation in T cells ameliorates lipopolysaccharide-induced inflammation of the large intestine

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  DOI: 10.3389/fimmu.2023.1135410
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10347374/
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Hypoxic niches attract and sequester tumor-associated macrophages and cytotoxic T cells and reprogram them for immunosuppression

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  DOI: 10.1016/j.immuni.2023.06.017
  
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A genetic method specifically delineates Th1-type Treg cells and their roles in tumor immunity

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  DOI: 10.1016/j.celrep.2023.112813
  
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sciencedirect.com/science/article/pii/S2211124723008240
May 2023
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Context-dependent activation of STING-interferon signaling by CD11b agonists enhances anti-tumor immunity

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1. scibot 26 May 2023
  
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  DOI: 10.1016/j.ccell.2023.04.018
  
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Jan 2023
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Enhancing PD-L1 Degradation by ITCH during MAPK Inhibitor Therapy Suppresses Acquired Resistance

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  DOI: 10.1158/2159-8290.CD-21-1463
  
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aacrjournals.org/cancerdiscovery/article/12/8/1942/707227/Enhancing-PD-L1-Degradation-by-ITCH-during-MAPK
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Low-Dose Radiotherapy Reverses Tumor Immune Desertification and Resistance to Immunotherapy

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  DOI: 10.1158/2159-8290.CD-21-0003
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9401506/
Dec 2022
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IL-5-producing CD4+ T cells and eosinophils cooperate to enhance response to immune checkpoint blockade in breast cancer

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  DOI: 10.1016/j.ccell.2022.11.014
  
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sciencedirect.com/science/article/pii/S153561082200561X
Nov 2022
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Re-purposing the pro-senescence properties of doxorubicin to introduce immunotherapy in breast cancer brain metastasis

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  DOI: 10.1016/j.xcrm.2022.100821
  
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sciencedirect.com/science/article/pii/S2666379122003809
Oct 2022
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Distinct biomarker profiles and TCR sequence diversity characterize the response to PD-L1 blockade in a mouse melanoma model

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  DOI: 10.1158/1541-7786.MCR-20-0881
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9533714/
May 2022
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Loss of T cell tolerance in the skin following immunopathology is linked to failed restoration of the dermal niche by recruited macrophages

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  DOI: 10.1016/j.celrep.2022.110819
  
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sciencedirect.com/science/article/pii/S2211124722005903
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Glutaminase inhibition impairs CD8 T cell activation in STK11-/Lkb1-deficient lung cancer

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1. scibot 05 May 2022
  
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  RRID: AB_467576
  
  DOI: 10.1016/j.cmet.2022.04.003
  
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cell.com/cell-metabolism/fulltext/S1550-4131(22)00130-9
Dec 2021
insight.jci.org insight.jci.org

Tnfrsf4-expressing regulatory T cells promote immune escape of chronic myeloid leukemia stem cells

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  RRID:AB_467576
  
  DOI: 10.1172/jci.insight.151797
  
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CD95/Fas protects triple negative breast cancer from anti-tumor activity of NK cells

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  DOI: 10.1016/j.isci.2021.103348
  
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Autotaxin impedes anti-tumor immunity by suppressing chemotaxis and tumor infiltration of CD8+ T cells

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  DOI: 10.1016/j.celrep.2021.110013
  
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Tumor-derived extracellular vesicles regulate tumor-infiltrating regulatory T cells via the inhibitory immunoreceptor CD300a

1
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  DOI: 10.7554/eLife.61999
  
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Sep 2021
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Effector T cell responses unleashed by regulatory T cell ablation exacerbate oral squamous cell carcinoma

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  DOI: 10.1016/j.xcrm.2021.100399
  
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Anti-PD-1/L1 lead-in before MAPK inhibitor combination maximizes antitumor immunity and efficacy

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  DOI: 10.1016/j.ccell.2021.07.023
  
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Untitled document

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  DOI: 10.1016/j.devcel.2018.11.010
  
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An Immunocompetent Mouse Model of HPV16(+) Head and Neck Squamous Cell Carcinoma

1
1. scibot 31 Jul 2021
  
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  Rat anti-mouse Foxp3
  
  DOI: 10.1016/j.celrep.2019.10.005
  
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Untitled document

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  DOI: 10.1016/j.celrep.2018.09.056
  
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SPNS2 enables T cell egress from lymph nodes during an immune response

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  DOI: 10.1016/j.celrep.2021.109368
  
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Jun 2021
academic.oup.com academic.oup.com

Exposure to propylparaben during pregnancy and lactation induces long-term alterations to the mammary gland in mice

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  DOI: 10.1210/endocr/bqab041
  
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Apr 2021
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Programing of an Intravascular Immune Firewall by the Gut Microbiota Protects against Pathogen Dissemination during Infection

1
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  DOI: 10.1016/j.chom.2020.07.014
  
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Sepsis impedes EAE disease development and diminishes autoantigen-specific naive CD4 T cells

1
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  AB_467576
  
  DOI: 10.7554/eLife.55800
  
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Sep 2020
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Methionine Metabolism Shapes T Helper Cell Responses through Regulation of Epigenetic Reprogramming

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  DOI: 10.1016/j.cmet.2020.01.006
  
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Myosin II Reactivation and Cytoskeletal Remodeling as a Hallmark and a Vulnerability in Melanoma Therapy Resistance

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  DOI: 10.1016/j.ccell.2019.12.003
  
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FOXD3 Regulates VISTA Expression in Melanoma

1
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  DOI: 10.1016/j.celrep.2019.12.036
  
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Dendritic Cell Paucity Leads to Dysfunctional Immune Surveillance in Pancreatic Cancer

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  DOI: 10.1016/j.ccell.2020.02.008
  
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Jan 2020
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UVB-Induced Tumor Heterogeneity Diminishes Immune Response in Melanoma

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  DOI: 10.1016/j.cell.2019.08.032
  
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The Polycomb Repressor Complex 1 Drives Double-Negative Prostate Cancer Metastasis by Coordinating Stemness and Immune Suppression

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  DOI: 10.1016/j.ccell.2019.06.009
  
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Chronic Inflammation Directs an Olfactory Stem Cell Functional Switch from Neuroregeneration to Immune Defense

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  DOI: 10.1016/j.stem.2019.08.011
  
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High-Dimensional Analysis Delineates Myeloid and Lymphoid Compartment Remodeling during Successful Immune-Checkpoint Cancer Therapy

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Untitled document

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Non-conventional Inhibitory CD4+Foxp3−PD-1hi T Cells as a Biomarker of Immune Checkpoint Blockade Activity

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