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An MMP-14/STAT3 feedback loop upregulates PD-L1 to drive immunosuppression and tumorigenesis in bladder cancer

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1. scibot 06 Nov 2026
  
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  DOI: 10.1016/j.isci.2026.118071
  
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sciencedirect.com/science/article/pii/S2589004226034541
Oct 2026
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CXCR5 regulates CD8+/GZMB+ T cell infiltration and apoptotic signaling in breast cancer

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1. scibot 22 Oct 2026
  
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  DOI: 10.1016/j.isci.2026.117874
  
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sciencedirect.com/science/article/pii/S2589004226032578
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Reviving low-affinity glycan-targeting CAR with combinatorial design

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1. scibot 09 Oct 2026
  
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  DOI: 10.1016/j.xcrm.2026.103108
  
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sciencedirect.com/science/article/pii/S2666379126005252
Sep 2026
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Cancer cell-intrinsic rewiring of the colorectal cancer secretome

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1. scibot 24 Sep 2026
  
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  DOI: 10.1016/j.isci.2026.117525
  
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sciencedirect.com/science/article/pii/S2589004226029044
Aug 2026
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Latent effector T cells mediate immunotherapy responses in the bone marrow microenvironment

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1. scibot 11 Aug 2026
  
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  DOI: 10.1016/j.ccell.2026.07.011
  
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sciencedirect.com/science/article/pii/S1535610826003491
Jul 2026
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Arginine Deprivation of ASS1-Deficient Cancers Drives Mistranslation and Shared Neoepitope Production

1
1. scibot 17 Jul 2026
  
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  DOI: 10.1158/0008-5472.CAN-25-4773
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13370116/
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Serglycin Drives LAG3+ Treg Differentiation and Immunosuppression in Gastric Cancer

1
1. scibot 12 Jul 2026
  
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  RRID:AB_468855
  
  DOI: 10.1158/0008-5472.CAN-25-3071
  
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aacrjournals.org/cancerres/article/86/10/2395/784887/Serglycin-Drives-LAG3-Treg-Differentiation-and
May 2026
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Inflammatory CD4+ T cells can waive NRF2-dependent SLC7A11-mediated cystine uptake by using ASCT1

1
1. scibot 01 May 2026
  
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  DOI: 10.1016/j.isci.2026.115680
  
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sciencedirect.com/science/article/pii/S2589004226010552
Apr 2026
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Organ injury in systemic autoimmunity is mediated by stem-like CD8+ T cells arising from tissue-draining lymph nodes

1
1. scibot 23 Apr 2026
  
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  RRID:AB_468855
  
  DOI: 10.1016/j.immuni.2026.03.022
  
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sciencedirect.com/science/article/pii/S1074761326001330
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A tumor-promoting inflammatory SPP1+ macrophage—IL-6—CRP axis drives immune dysfunction in bladder cancer

1
1. scibot 14 Apr 2026
  
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  RRID:AB_468855
  
  DOI: 10.1158/2159-8290.CD-25-1774
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13069984/
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SHR-2005, an FcγR-Dependent CD40 Agonistic Antibody with Potent Antitumor Activities and Favorable Safety Profile

1
1. scibot 07 Apr 2026
  
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  RRID:AB_468855
  
  DOI: 10.1158/1535-7163.MCT-24-0999
  
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aacrjournals.org/mct/article/24/11/1671/766867/SHR-2005-an-Fc-R-Dependent-CD40-Agonistic-Antibody
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Loss of miR-29a/b1 cluster reprograms the tumor microenvironment and contributes to immunosuppression in lung cancer

1
1. scibot 01 Apr 2026
  
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  RRID:AB_468855
  
  DOI: 10.1158/2326-6066.CIR-25-1060
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13034170/
Mar 2026
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Medium-Chain Fatty Acid Receptor GPR84 Modulates Cytotoxic CD8 T cells Antitumor Immunity Through Metabolic Reprogramming

1
1. scibot 18 Mar 2026
  
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  RRID:AB_468855
  
  DOI: 10.1158/2326-6066.CIR-25-0695
  
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aacrjournals.org/cancerimmunolres/article/14/4/640/776520/Medium-Chain-Fatty-Acid-Receptor-GPR84-Modulates
Oct 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Identification of antigen-specific functional CD8+ T cells using an optofluidic system independent of epitope information

1
1. scibot 16 Oct 2025
  
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  RRID:AB_468855
  
  DOI: 10.1016/j.isci.2025.113600
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12519166/
Sep 2025
54.241.53.176 54.241.53.176

1-s2.0-S2589004225018619-main-html.html

1
1. scibot 23 Sep 2025
  
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  RRID:AB_468855
  
  DOI: 10.1016/j.isci.2025.113600
  
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54.241.53.176/64d4793caaf3e276a1407f2ade3185b52d29ff0a/1-s2.0-S2589004225018619-main-html.html
Jul 2025
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Coupling IL-2 with IL-10 to mitigate toxicity and enhance antitumor immunity

1
1. scibot 31 Jul 2025
  
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  RRID:AB_468855
  
  DOI: 10.1016/j.xcrm.2025.102257
  
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sciencedirect.com/science/article/pii/S2666379125003301
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The Integrated Stress Response Pathway Coordinates Translational Control of Multiple Immune Checkpoints in Lung Cancer

1
1. scibot 17 Jul 2025
  
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  RRID:AB_468855
  
  DOI: 10.1158/0008-5472.CAN-24-3844
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12260515/
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Subclonal immune evasion in non-small cell lung cancer

1
1. scibot 03 Jul 2025
  
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  RRID:AB_468855
  
  DOI: 10.1016/j.ccell.2025.06.012
  
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sciencedirect.com/science/article/pii/S1535610825002624
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Isolation of mitochondrial mutation-specific T cell receptors

1
1. scibot 03 Jul 2025
  
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  RRID:AB_468855
  
  DOI: 10.1093/jimmun/vkaf139
  
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academic.oup.com/jimmunol/advance-article/doi/10.1093/jimmun/vkaf139/8178814
May 2025
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Step-Wise Assembly of LAT Signaling Clusters Immediately After T Cell Receptor Triggering Contributes to Signal Propagation

1
1. scibot 21 May 2025
  
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  RRID:AB_468855
  
  DOI: 10.3390/ijms26094076
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12071625/
52.53.155.43 52.53.155.43

PDF-html.html

1
1. scibot 20 May 2025
  
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  RRID:AB_468855
  
  DOI: 10.1158/0008-5472.can-24-3844
  
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52.53.155.43/0976643c3f79ff08c8e38df9c7b0ed5aea42f921/PDF-html.html
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Characterization and comparative analysis of multifunctional natural killer cell engagers during antitumor responses

1
1. scibot 19 May 2025
  
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  DOI: 10.1016/j.xcrm.2025.102117
  
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sciencedirect.com/science/article/pii/S2666379125001909
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Engineering ERα degraders with pleiotropic ubiquitin ligase ligands maximizes therapeutic efficacy by co-opting distinct effector ligases

1
1. scibot 17 May 2025
  
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  DOI: 10.1016/j.chembiol.2025.04.008
  
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sciencedirect.com/science/article/pii/S245194562500131X
Apr 2025
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Impact of rosuvastatin on the memory potential and functionality of CD8+ T cells from people with HIV

1
1. scibot 01 Apr 2025
  
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  RRID:AB_468855
  
  DOI: 10.1016/j.ebiom.2025.105672
  
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sciencedirect.com/science/article/pii/S2352396425001161
Jan 2025
academic.oup.com academic.oup.com

IFNγ induces epithelial reprogramming driving CXCL11-mediated T cell migration

1
1. scibot 31 Jan 2025
  
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  RRID: AB_468855
  
  DOI: 10.1093/jleuko/qiae205
  
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academic.oup.com/jleukbio/advance-article/doi/10.1093/jleuko/qiae205/7762566
Aug 2024
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Calcineurin is an adaptor required for assembly of the TCR signaling complex

1
1. scibot 19 Aug 2024
  
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  RRID:AB_468855
  
  DOI: 10.1016/j.celrep.2024.114568
  
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cell.com/cell-reports/fulltext/S2211-1247(24)00897-0
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Disc Large Homolog 1 Is Critical for Early T Cell Receptor Micro Cluster Formation and Activation in Human T Cells

1
1. scibot 02 Aug 2024
  
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  16-0037-85
  
  DOI: 10.3390/vaccines9121446
  
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mdpi.com/2076-393X/9/12/1446/htm
Jul 2024
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Stimulation-induced cytokine polyfunctionality as a dynamic concept

1
1. scibot 20 Jul 2024
  
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  DOI: 10.7554/eLife.89781
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11254380/
Jun 2024
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Chemotherapy-induced intestinal epithelial damage directly promotes galectin-9-driven modulation of T cell behavior

1
1. scibot 29 Jun 2024
  
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  RRID:AB_468855
  
  DOI: 10.1016/j.isci.2024.110072
  
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cell.com/iscience/abstract/S2589-0042(24)01297-5
May 2024
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Transient hydroxycholesterol treatment restrains TCR signaling to promote long-term immunity

1
1. scibot 17 May 2024
  
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  DOI: 10.1016/j.chembiol.2024.04.005
  
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sciencedirect.com/science/article/pii/S2451945624001673
Mar 2024
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Multimodal stimulation screens reveal unique and shared genes limiting T cell fitness

3
1. scibot 15 Mar 2024
  
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  RRID:AB_468855
  
  DOI: 10.1016/j.ccell.2024.02.016
  
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2. scibot 15 Mar 2024
  
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  RRID:AB_468855
  
  DOI: 10.1016/j.ccell.2024.02.016
  
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3. scibot 15 Mar 2024
  
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  RRID:AB_468855
  
  DOI: 10.1016/j.ccell.2024.02.016
  
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sciencedirect.com/science/article/pii/S1535610824000606
Feb 2024
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Cell-intrinsic PD-L1 ablation sustains effector CD8+ T cell responses and promotes antitumor T cell therapy

1
1. scibot 02 Feb 2024
  
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  RRID:AB_468855
  
  DOI: 10.1016/j.celrep.2024.113712
  
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sciencedirect.com/science/article/pii/S2211124724000408
Jun 2023
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Single-cell deep phenotyping of cytokine release unmasks stimulation-specific biological signatures and distinct secretion dynamics

1
1. scibot 23 Jun 2023
  
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  RRID:AB_468855
  
  DOI: 10.1016/j.crmeth.2023.100502
  
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sciencedirect.com/science/article/pii/S2667237523001315
May 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

LCL161 enhances expansion and survival of engineered anti-tumor T cells but is restricted by death signaling

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  AB_468855
  
  DOI: 10.3389/fimmu.2023.1179827
  
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Feb 2023
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An adverse tumor-protective effect of IDO1 inhibition

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  DOI: 10.1016/j.xcrm.2023.100941
  
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Jan 2023
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CD28-CAR-T cell activation through FYN kinase signaling rather than LCK enhances therapeutic performance

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  DOI: 10.1016/j.xcrm.2023.100917
  
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CD8+ T cell-intrinsic IL-6 signaling promotes resistance to anti-PD-L1 immunotherapy

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  RRID:AB_468855
  
  DOI: 10.1016/j.xcrm.2022.100878
  
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Cancer genes disfavoring T cell immunity identified via integrated systems approach

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  DOI: 10.1016/j.celrep.2022.111153
  
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Jul 2022
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Tissue-resident memory and circulating T cells are early responders to pre-surgical cancer immunotherapy

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  DOI: 10.1016/j.cell.2022.06.018
  
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Jun 2022
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RNF31 inhibition sensitizes tumors to bystander killing by innate and adaptive immune cells

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  DOI: 10.1016/j.xcrm.2022.100655
  
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Mar 2022
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Multiple Early Factors Anticipate Post-Acute COVID-19 Sequelae

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  DOI: 10.1016/j.cell.2022.01.014
  
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Dec 2021
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CD4+CCR6+ T cells dominate the BCG-induced transcriptional signature

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1. scibot 29 Dec 2021
  
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  AB_468855
  
  DOI: 10.1016/j.ebiom.2021.103746
  
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Nov 2021
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TGF-β orchestrates the phenotype and function of monocytic myeloid-derived suppressor cells in colorectal cancer

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  RRID:AB_468855
  
  DOI: 10.1007/s00262-021-03081-5
  
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Aug 2021
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Untitled document

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  DOI: 10.1016/j.devcel.2018.11.010
  
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Untitled document

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  DOI: 10.1016/j.clim.2017.03.014
  
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Jul 2021
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Untitled document

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  DOI: 10.1016/j.chom.2017.03.008
  
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Humans with inherited T cell CD28 deficiency are susceptible to skin papillomaviruses but are otherwise healthy

1
1. scibot 02 Jul 2021
  
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  RRID:AB_468855
  
  DOI: 10.1016/j.cell.2021.06.004
  
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Apr 2021
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Multi-phenotype CRISPR-Cas9 Screen Identifies p38 Kinase as a Target for Adoptive Immunotherapies

1
1. scibot 17 Apr 2021
  
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  RRID:AB_468855
  
  DOI: 10.1016/j.ccell.2020.05.004
  
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Dec 2020
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Multi-color Molecular Visualization of Signaling Proteins Reveals How C-Terminal Src Kinase Nanoclusters Regulate T Cell Receptor Activation

1
1. scibot 30 Dec 2020
  
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  RRID:AB_468855
  
  DOI: 10.1016/j.celrep.2020.108523
  
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Nov 2020
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Multi-Omics Resolves a Sharp Disease-State Shift between Mild and Moderate COVID-19

1
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  RRID:AB_468855
  
  DOI: 10.1016/j.cell.2020.10.037
  
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Sep 2020
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Metformin Enhances Autophagy and Normalizes Mitochondrial Function to Alleviate Aging-Associated Inflammation

1
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  RRID:AB_468855
  
  DOI: 10.1016/j.cmet.2020.04.015
  
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Multiple Signaling Roles of CD3ε and Its Application in CAR-T Cell Therapy

1
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  DOI: 10.1016/j.cell.2020.07.018
  
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High CD26 and Low CD94 Expression Identifies an IL-23 Responsive Vδ2+ T Cell Subset with a MAIT Cell-like Transcriptional Profile

1
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  RRID:AB_468855
  
  DOI: 10.1016/j.celrep.2020.107773
  
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sciencedirect.com/science/article/pii/S2211124720307531
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Human Liver Memory CD8+ T Cells Use Autophagy for Tissue Residence

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  RRID:AB_468855
  
  DOI: 10.1016/j.celrep.2019.12.050
  
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sciencedirect.com/science/article/pii/S2211124719317073
Jan 2020
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Hepatocytes Delete Regulatory T Cells by Enclysis, a CD4+ T Cell Engulfment Process

1
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  RRID:AB_468855
  
  DOI: 10.1016/j.celrep.2019.09.068
  
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Age-Related Dopaminergic Innervation Augments T Helper 2-Type Allergic Inflammation in the Postnatal Lung

1
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  DOI: 10.1016/j.immuni.2019.10.002
  
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Augmenting Immunotherapy Impact by Lowering Tumor TNF Cytotoxicity Threshold

1
1. scibot 13 Jan 2020
  
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  RRID:AB_468855
  
  DOI: 10.1016/j.cell.2019.06.014
  
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currentprotocols.onlinelibrary.wiley.com currentprotocols.onlinelibrary.wiley.com

Untitled document

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  DOI: 10.1002/cpim.69
  
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currentprotocols.onlinelibrary.wiley.com/doi/full/10.1002/cpim.69
Nov 2018
www-sciencedirect-com.ezp-prod1.hul.harvard.edu www-sciencedirect-com.ezp-prod1.hul.harvard.edu

Generation of Tumor-Reactive T Cells by Co-culture of Peripheral Blood Lymphocytes and Tumor Organoids

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www-sciencedirect-com.ezp-prod1.hul.harvard.edu/science/article/pii/S0092867418309036
Nov 2017
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Defective HIV-1 Proviruses Are Expressed and Can Be Recognized by Cytotoxic T Lymphocytes, which Shape the Proviral Landscape

1
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Prolonged immunomodulation in inflammatory arthritis using the selective Kv1.3 channel blocker HsTX1[R14A] and its PEGylated analog

1
1. scibot 08 Nov 2017
  
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  Curator: @kaitlinsung
  
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Human Epistatic Interaction Controls IL7R Splicing and Increases Multiple Sclerosis Risk

1
1. scibot 08 Nov 2017
  
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sciencedirect.com/science/article/pii/S0092867417302866

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