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Protocol for intranuclear Nrf2 detection in activated mouse, human, and Jurkat T cells by spectral flow cytometry

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pmc.ncbi.nlm.nih.gov/articles/PMC12915187/
Feb 2026
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Activation status of astrocytes drives the MS/NMOSD therapeutic paradox: Insights from IFNAR1 signaling

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sciencedirect.com/science/article/pii/S2211124725016857
Oct 2025
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Treg-microglia partnership in the injured spinal cord preserves Treg cell function and regulates microglial cholesterol metabolism

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Aug 2025
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Nrf2 drives activation-driven expansion of CD4+T cells by modulating glucose and glutamine metabolism

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Jul 2025
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Ce6 derivative photodynamic therapy triggers PANoptosis and enhances antitumor immunity with LAG3 blockade in cutaneous squamous cell carcinoma

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May 2025
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Thymic dendritic cell-derived IL-27p28 promotes the establishment of functional bias against IFN-γ production in newly generated CD4+ T cells through STAT1-related epigenetic mechanisms

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Age-related impairment of intestinal inflammation resolution through an eicosanoid-immune-microbiota axis

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sciencedirect.com/science/article/pii/S1931312825001477
Apr 2025
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SEMA3G-NRP1 Signaling Functions as an Immune Checkpoint that Enables Tumor Immune Evasion by Impairing T Cell Cytotoxicity

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1. scibot 17 Apr 2025
  
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  DOI: 10.1158/0008-5472.CAN-24-2223
  
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aacrjournals.org/cancerres/article/85/5/912/751997/SEMA3G-NRP1-Signaling-Functions-as-an-Immune
Feb 2025
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52.53.155.43/752d85b7b45cbe249ff1ba5f1b04c7c2ca434b68/can-24-2223-html.html
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Nanrilkefusp alfa (SOT101), an IL-15 receptor βγ superagonist, as a single agent or with anti-PD-1 in patients with advanced cancers

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MAIT cells protect against sterile lung injury

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sciencedirect.com/science/article/pii/S2211124725000464
Jan 2025
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Bi-directional communication between intrinsic enteric neurons and ILC2s inhibits host defense against helminth infection

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Dec 2024
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Hyperreactive B cells instruct their elimination by T cells to curb autoinflammation and lymphomagenesis

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1. scibot 29 Dec 2024
  
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cell.com/immunity/abstract/S1074-7613(24)00538-7
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Interleukin-2-secreting T helper cells promote extra-follicular B cell maturation via intrinsic regulation of a B cell mTOR-AKT-Blimp-1 axis

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Nov 2024
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Local adaptive immunity in atherosclerosis with T cell activation by aortic DCs accelerates pathogenesis

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pmc.ncbi.nlm.nih.gov/articles/PMC11536043/
Sep 2024
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The rebalancing of the immune system at the maternal-fetal interface ameliorates autism-like behavior in adult offspring

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Neoself-antigens are the primary target for autoreactive T cells in human lupus

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1. scibot 17 Sep 2024
  
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  DOI: 10.1016/j.cell.2024.08.025
  
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The transcription regulator ID3 maintains tumor-specific memory CD8+ T cells in draining lymph nodes during tumorigenesis

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1. scibot 04 Sep 2024
  
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Jul 2024
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Transcriptional programming mediated by the histone demethylase KDM5C regulates dendritic cell population heterogeneity and function

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Progestogen-driven B7-H4 contributes to onco-fetal immune tolerance

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sciencedirect.com/science/article/pii/S0092867424006524
May 2024
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The histone lysine methyltransferase MLL1 regulates the activation and functional specialization of regulatory T cells

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Apr 2024
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LKB1 prevents ILC2 exhaustion to enhance antitumor immunity

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Mar 2024
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Ex vivo activation of the GCN2 pathway metabolically reprograms T cells, leading to enhanced adoptive cell therapy

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Feb 2024
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Cell-intrinsic PD-L1 ablation sustains effector CD8+ T cell responses and promotes antitumor T cell therapy

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Reversible, tunable epigenetic silencing of TCF1 generates flexibility in the T cell memory decision

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Dec 2023
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Attenuation of allergen-specific immunotherapy for atopic dermatitis by ectopic colonization of Brevundimonas vesicularis in the intestine

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Nov 2023
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An essential role for miR-15/16 in Treg suppression and restriction of proliferation

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ncbi.nlm.nih.gov/pmc/articles/PMC10664750/
Aug 2023
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Lymph node sharing between pancreas, gut, and liver leads to immune crosstalk and regulation of pancreatic autoimmunity

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Jul 2023
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The splicing isoform Foxp3Δ2 differentially regulates tTreg and pTreg homeostasis

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Jun 2023
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The parabrachial nucleus elicits a vigorous corticosterone feedback response to the pro-inflammatory cytokine IL-1β

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  DOI: 10.1016/j.neuron.2023.05.009
  
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sciencedirect.com/science/article/pii/S0896627323003823
May 2023
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The eIF4EBP-eIF4E axis regulates CD4+ T cell differentiation through modulation of T cell activation and metabolism

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ncbi.nlm.nih.gov/pmc/articles/PMC10176268/
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Mechanisms Regulating the loss of Tregs in HUPO mice that Develop Spontaneous Inflammatory Arthritis

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  DOI: 10.1016/j.isci.2023.106734
  
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sciencedirect.com/science/article/pii/S2589004223008118
Apr 2023
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cDC1 coordinate innate and adaptive responses in the omentum required for T cell priming and memory

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1. scibot 05 Apr 2023
  
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  DOI: 10.1126/sciimmunol.abq7432
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9835709/
Jun 2022
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Androgen receptor-mediated CD8+ T cell stemness programs drive sex differences in antitumor immunity

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  DOI: 10.1016/j.immuni.2022.05.012
  
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The spliceosome component Usp39 controls B cell development by regulating immunoglobulin gene rearrangement

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IL-2/JES6-1 mAb complexes dramatically increase sensitivity to LPS through IFN-γ production by CD25+Foxp3- T cells

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GPR120 induces regulatory dendritic cells by inhibiting HK2-dependent glycolysis to alleviate fulminant hepatic failure

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MicroRNA-29 specifies age-related differences in the CD8+ T cell immune response

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Redundant cytokine requirement for intestinal microbiota-induced Th17 cell differentiation in draining lymph nodes

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ZEB1 promotes pathogenic Th1 and Th17 cell differentiation in multiple sclerosis

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Untitled document

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A stochastic epigenetic switch controls the dynamics of T-cell lineage commitment

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Trichinella spiralis Paramyosin Induces Colonic Regulatory T Cells to Mitigate Inflammatory Bowel Disease

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The Conserved Non-coding Sequences CNS6 and CNS9 Control Cytokine-Induced Rorc Transcription during T Helper 17 Cell Differentiation

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Near-infrared photoimmunotherapy targeting human-EGFR in a mouse tumor model simulating current and future clinical trials

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  anti-CD25
  
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Protein Prenylation Drives Discrete Signaling Programs for the Differentiation and Maintenance of Effector Treg Cells

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Distinct Foxp3 enhancer elements coordinate development, maintenance, and function of regulatory T cells

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A distal Foxp3 enhancer enables interleukin-2 dependent thymic Treg cell lineage commitment for robust immune tolerance

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Ablation of Transcription Factor IRF4 Promotes Transplant Acceptance by Driving Allogenic CD4+ T Cell Dysfunction

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Murine HSCs contribute actively to native hematopoiesis but with reduced differentiation capacity upon aging

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The AP1 Transcription Factor Fosl2 Promotes Systemic Autoimmunity and Inflammation by Repressing Treg Development

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Hybrid Gene Origination Creates Human-Virus Chimeric Proteins during Infection

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Differential Alternative Polyadenylation Landscapes Mediate Hematopoietic Stem Cell Activation and Regulate Glutamine Metabolism

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Impaired phagocytic function in CX3CR1+ tissue‐resident skeletal muscle macrophages prevents muscle recovery after influenza A virus‐induced pneumonia in old mice

1
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  CD25 clone PC61.5 APC
  
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Interleukin-33 Induces the Enzyme Tryptophan Hydroxylase 1 to Promote Inflammatory Group 2 Innate Lymphoid Cell-Mediated Immunity

1
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Soluble recombinant human thrombomodulin suppresses inflammation-induced gastrointestinal tumor growth in a murine peritonitis model

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Neuropeptide CGRP Limits Group 2 Innate Lymphoid Cell Responses and Constrains Type 2 Inflammation

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Amino Acids License Kinase mTORC1 Activity and Treg Cell Function via Small G Proteins Rag and Rheb

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IGF-2 Preprograms Maturing Macrophages to Acquire Oxidative Phosphorylation-Dependent Anti-inflammatory Properties

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  DOI: 10.1016/j.cmet.2019.01.006
  
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Untitled document

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Hippo Kinases Mst1 and Mst2 Sense and Amplify IL-2R−STAT5 Signaling in Regulatory T Cells to Establish Stable Regulatory Activity

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Untitled document

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  DOI: 10.7554/eLife.41258
  
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Blimp-1 Functions as a Molecular Switch to Prevent Inflammatory Activity in Foxp3+RORγt+ Regulatory T Cells

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LAG3+ Regulatory T Cells Restrain Interleukin-23-Producing CX3CR1+ Gut-Resident Macrophages during Group 3 Innate Lymphoid Cell-Driven Colitis

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Developmental Origin Governs CD8+ T Cell Fate Decisions during Infection

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T Cell Receptor-Regulated TGF-β Type I Receptor Expression Determines T Cell Quiescence and Activation

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  RRID:AB_469366
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academic.oup.com/endo/article/158/10/3140/4060086
www.sciencedirect.com www.sciencedirect.com

Ablation of Transcription Factor IRF4 Promotes Transplant Acceptance by Driving Allogenic CD4+ T Cell Dysfunction

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1. scibot 05 Nov 2018
  
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  RRID:AB_469366
  
  Resource used:
  
  (Thermo Fisher Scientific Cat# 17-0251-82, RRID:AB_469366)
  
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  RRID:AB_469366
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sciencedirect.com/science/article/pii/S1074761317304806
www.sciencedirect.com www.sciencedirect.com

Interleukin-33-Activated Islet-Resident Innate Lymphoid Cells Promote Insulin Secretion through Myeloid Cell Retinoic Acid Production

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1. scibot 05 Nov 2018
  
  in Public
  
  RRID:AB_469366
  
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  (Thermo Fisher Scientific Cat# 17-0251-82, RRID:AB_469366)
  
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  RRID:AB_469366
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sciencedirect.com/science/article/pii/S1074761317304703
Nov 2017
www.jneurosci.org www.jneurosci.org

Plasminogen Deficiency Delays the Onset and Protects from Demyelination and Paralysis in Autoimmune Neuroinflammatory Disease

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1. scibot 08 Nov 2017
  
  in Public
  
  AB_469366
  
  Curator: @chewbeccax
  
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  (Thermo Fisher Scientific Cat# 17-0251-82, RRID:AB_469366)
  
  SciCrunch record: RRID:AB_469366
  
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  RRID:AB_469366 RRIDCUR:Validated
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jneurosci.org/content/37/14/3776

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