Hypothesis

31 Matching Annotations

Oct 2025
www.sciencedirect.com www.sciencedirect.com

Notch3 destabilizes regulatory T cells to drive autoimmune neuroinflammation in multiple sclerosis

1
1. scibot 04 Oct 2025
  
  in Public
  
  RRID:AB_469410
  
  DOI: 10.1016/j.immuni.2025.09.007
  
  Resource: (Thermo Fisher Scientific Cat# 17-0621-82, RRID:AB_469410)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_469410
  
  What is this?
  
  RRID:AB_469410
Visit annotations in context

Tags

RRID:AB_469410

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1074761325004182
Mar 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Pathway-instructed therapeutic selection of ruxolitinib reduces neuroinflammation in fungal postinfectious inflammatory syndrome

1
1. scibot 27 Mar 2025
  
  in Public
  
  RRID:AB_469410
  
  DOI: 10.1126/sciadv.adi9885
  
  Resource: (Thermo Fisher Scientific Cat# 17-0621-82, RRID:AB_469410)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_469410
  
  What is this?
  
  RRID:AB_469410
Visit annotations in context

Tags

RRID:AB_469410

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11927619/
www.science.org www.science.org

Pathway-instructed therapeutic selection of ruxolitinib reduces neuroinflammation in fungal postinfectious inflammatory syndrome

1
1. scibot 24 Mar 2025
  
  in Public
  
  RRID:AB_469410
  
  DOI: 10.1126/sciadv.adi9885
  
  Resource: (Thermo Fisher Scientific Cat# 17-0621-82, RRID:AB_469410)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_469410
  
  What is this?
  
  RRID:AB_469410
Visit annotations in context

Tags

RRID:AB_469410

Annotators

scibot

URL

science.org/doi/10.1126/sciadv.adi9885
Jun 2024
link.springer.com link.springer.com

Gasdermin D deficiency aborts myeloid calcium influx to drive granulopoiesis in lupus nephritis

1
1. scibot 06 Jun 2024
  
  in Public
  
  RRID:AB_469410
  
  DOI: 10.1186/s12964-024-01681-z
  
  Resource: (Thermo Fisher Scientific Cat# 17-0621-82, RRID:AB_469410)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_469410
  
  What is this?
  
  RRID:AB_469410
Visit annotations in context

Tags

RRID:AB_469410

Annotators

scibot

URL

link.springer.com/article/10.1186/s12964-024-01681-z
May 2024
www.sciencedirect.com www.sciencedirect.com

Transient hydroxycholesterol treatment restrains TCR signaling to promote long-term immunity

1
1. scibot 17 May 2024
  
  in Public
  
  RRID:AB_469410
  
  DOI: 10.1016/j.chembiol.2024.04.005
  
  Resource: (Thermo Fisher Scientific Cat# 17-0621-82, RRID:AB_469410)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_469410
  
  What is this?
  
  RRID:AB_469410
Visit annotations in context

Tags

RRID:AB_469410

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2451945624001673
www.sciencedirect.com www.sciencedirect.com

IL-7-primed bystander CD8 tumor-infiltrating lymphocytes optimize the antitumor efficacy of T cell engager immunotherapy

1
1. scibot 14 May 2024
  
  in Public
  
  RRID:AB_469410
  
  DOI: 10.1016/j.xcrm.2024.101567
  
  Resource: (Thermo Fisher Scientific Cat# 17-0621-82, RRID:AB_469410)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_469410
  
  What is this?
  
  RRID:AB_469410
Visit annotations in context

Tags

RRID:AB_469410

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2666379124002593
Dec 2023
www.sciencedirect.com www.sciencedirect.com

MHC class II regulation of CD8+ T cell tolerance and implications in autoimmunity and cancer immunotherapy

1
1. scibot 01 Dec 2023
  
  in Public
  
  RRID:AB_469410
  
  DOI: 10.1016/j.celrep.2023.113452
  
  Resource: (Thermo Fisher Scientific Cat# 17-0621-82, RRID:AB_469410)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_469410
  
  What is this?
  
  RRID:AB_469410
Visit annotations in context

Tags

RRID:AB_469410

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S221112472301464X
Sep 2023
www.sciencedirect.com www.sciencedirect.com

Regulatory T cells require IL6 receptor alpha signaling to control skeletal muscle function and regeneration

1
1. scibot 30 Sep 2023
  
  in Public
  
  RRID:AB_469410
  
  DOI: 10.1016/j.cmet.2023.08.010
  
  Resource: (Thermo Fisher Scientific Cat# 17-0621-82, RRID:AB_469410)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_469410
  
  What is this?
  
  RRID:AB_469410
Visit annotations in context

Tags

RRID:AB_469410

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1550413123003315
Jul 2023
www.sciencedirect.com www.sciencedirect.com

TCR-independent CD137 (4-1BB) signaling promotes CD8+-exhausted T cell proliferation and terminal differentiation

1
1. scibot 01 Jul 2023
  
  in Public
  
  RRID:AB_469410
  
  DOI: 10.1016/j.immuni.2023.06.007
  
  Resource: (Thermo Fisher Scientific Cat# 17-0621-82, RRID:AB_469410)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_469410
  
  What is this?
  
  RRID:AB_469410
Visit annotations in context

Tags

RRID:AB_469410

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1074761323002649
Jun 2023
www.sciencedirect.com www.sciencedirect.com

Cholesterol efflux pathways hinder KRAS-driven lung tumor progenitor cell expansion

1
1. scibot 02 Jun 2023
  
  in Public
  
  RRID:AB_469410
  
  DOI: 10.1016/j.stem.2023.05.005
  
  Resource: (Thermo Fisher Scientific Cat# 17-0621-82, RRID:AB_469410)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_469410
  
  What is this?
  
  RRID:AB_469410
Visit annotations in context

Tags

RRID:AB_469410

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1934590923001753
May 2023
www.sciencedirect.com www.sciencedirect.com

Exhaustion-associated cholesterol deficiency dampens the cytotoxic arm of antitumor immunity

1
1. scibot 27 May 2023
  
  in Public
  
  RRID:AB_469410
  
  DOI: 10.1016/j.ccell.2023.04.016
  
  Resource: (Thermo Fisher Scientific Cat# 17-0621-82, RRID:AB_469410)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_469410
  
  What is this?
  
  RRID:AB_469410
Visit annotations in context

Tags

RRID:AB_469410

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1535610823001423
Oct 2022
www.sciencedirect.com www.sciencedirect.com

The primordial differentiation of tumor-specific memory CD8+ T cells as bona fide responders to PD-1/PD-L1 blockade in draining lymph nodes

1
1. scibot 09 Oct 2022
  
  in Public
  
  RRID:AB_469410
  
  DOI: 10.1016/j.cell.2022.09.020
  
  Resource: (Thermo Fisher Scientific Cat# 17-0621-82, RRID:AB_469410)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_469410
  
  What is this?
  
  RRID:AB_469410
Visit annotations in context

Tags

RRID:AB_469410

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0092867422011928
Apr 2022
www.sciencedirect.com www.sciencedirect.com

Differential regulation of transcription factor T-bet induction during NK cell development and T helper-1 cell differentiation

1
1. scibot 07 Apr 2022
  
  in Public
  
  RRID:AB_469410
  
  DOI: 10.1016/j.immuni.2022.03.005
  
  Resource: (Thermo Fisher Scientific Cat# 17-0621-82, RRID:AB_469410)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_469410
  
  What is this?
  
  RRID:AB_469410
Visit annotations in context

Tags

RRID:AB_469410

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1074761322001285
Aug 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A stochastic epigenetic switch controls the dynamics of T-cell lineage commitment

1
1. scibot 07 Aug 2021
  
  in Public
  
  RRID:AB_469410
  
  DOI: 10.7554/eLife.37851
  
  Resource: (Thermo Fisher Scientific Cat# 17-0621-82, RRID:AB_469410)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_469410
  
  What is this?
  
  RRID:AB_469410
Visit annotations in context

Tags

RRID:AB_469410

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC6245732/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

1
1. scibot 05 Aug 2021
  
  in Public
  
  RRID:AB_469410
  
  DOI: 10.1016/j.cmet.2017.08.008
  
  Resource: (Thermo Fisher Scientific Cat# 17-0621-82, RRID:AB_469410)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_469410
  
  What is this?
  
  RRID:AB_469410
Visit annotations in context

Tags

RRID:AB_469410

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC5627977/
Jul 2021
www.sciencedirect.com www.sciencedirect.com

Distinct Regulation of Th17 and Th1 Cell Differentiation by Glutaminase-Dependent Metabolism

1
1. scibot 30 Jul 2021
  
  in Public
  
  RRID:AB_469410
  
  DOI: 10.1016/j.cell.2018.10.001
  
  Resource: (Thermo Fisher Scientific Cat# 17-0621-82, RRID:AB_469410)
  
  Curator: @Jmenke
  
  SciCrunch record: RRID:AB_469410
  
  What is this?
  
  RRIDCUR:Validated RRID:AB_469410
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_469410

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0092867418313096
www.sciencedirect.com www.sciencedirect.com

Untitled document

1
1. scibot 29 Jul 2021
  
  in Public
  
  RRID:AB_469410
  
  DOI: 10.1016/j.immuni.2018.09.004
  
  Resource: (Thermo Fisher Scientific Cat# 17-0621-82, RRID:AB_469410)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_469410
  
  What is this?
  
  RRID:AB_469410
Visit annotations in context

Tags

RRID:AB_469410

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1074761318303959
Jun 2021
www.cell.com www.cell.com

Synchronous effects of targeted mitochondrial complex I inhibitors on tumor and immune cells abrogate melanoma progression

1
1. scibot 25 Jun 2021
  
  in Public
  
  RRID:AB_469410
  
  DOI: 10.1016/j.isci.2021.102653
  
  Resource: (Thermo Fisher Scientific Cat# 17-0621-82, RRID:AB_469410)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_469410
  
  What is this?
  
  RRID:AB_469410
Visit annotations in context

Tags

RRID:AB_469410

Annotators

scibot

URL

cell.com/iscience/abstract/S2589-0042(21)00621-0
May 2021
www.sciencedirect.com www.sciencedirect.com

Eomes-Dependent Loss of the Co-activating Receptor CD226 Restrains CD8+ T Cell Anti-tumor Functions and Limits the Efficacy of Cancer Immunotherapy

1
1. scibot 07 May 2021
  
  in Public
  
  RRID:AB_469410
  
  DOI: 10.1016/j.immuni.2020.09.006
  
  Resource: (Thermo Fisher Scientific Cat# 17-0621-82, RRID:AB_469410)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_469410
  
  What is this?
  
  RRID:AB_469410
Visit annotations in context

Tags

RRID:AB_469410

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1074761320304003
Apr 2021
www.sciencedirect.com www.sciencedirect.com

Near-infrared photoimmunotherapy targeting human-EGFR in a mouse tumor model simulating current and future clinical trials

1
1. scibot 30 Apr 2021
  
  in Public
  
  anti-CD62L
  
  DOI: 10.1016/j.ebiom.2021.103345
  
  Resource: (Thermo Fisher Scientific Cat# 17-0621-82, RRID:AB_469410)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_469410
  
  What is this?
  
  RRIDCUR:Missing RRID:AB_469410
Visit annotations in context

Tags

RRID:AB_469410

RRIDCUR:Missing

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2352396421001389
www.sciencedirect.com www.sciencedirect.com

Notch4 signaling limits regulatory T-cell-mediated tissue repair and promotes severe lung inflammation in viral infections

1
1. scibot 29 Apr 2021
  
  in Public
  
  RRID:AB_469410
  
  DOI: 10.1016/j.immuni.2021.04.002
  
  Resource: (Thermo Fisher Scientific Cat# 17-0621-82, RRID:AB_469410)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_469410
  
  What is this?
  
  RRID:AB_469410
Visit annotations in context

Tags

RRID:AB_469410

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1074761321001394
www.sciencedirect.com www.sciencedirect.com

The PD-1/PD-L1-Checkpoint Restrains T cell Immunity in Tumor-Draining Lymph Nodes

1
1. scibot 22 Apr 2021
  
  in Public
  
  RRID:AB_469410
  
  DOI: 10.1016/j.ccell.2020.09.001
  
  Resource: (Thermo Fisher Scientific Cat# 17-0621-82, RRID:AB_469410)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_469410
  
  What is this?
  
  RRIDCUR:Validated RRID:AB_469410
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_469410

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1535610820304323
Dec 2020
www.sciencedirect.com www.sciencedirect.com

The Methyltransferase DOT1L Controls Activation and Lineage Integrity in CD4+ T Cells during Infection and Inflammation

1
1. scibot 17 Dec 2020
  
  in Public
  
  RRID:AB_469410
  
  DOI: 10.1016/j.celrep.2020.108505
  
  Resource: (Thermo Fisher Scientific Cat# 17-0621-82, RRID:AB_469410)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_469410
  
  What is this?
  
  RRIDCUR:Validated RRID:AB_469410
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_469410

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124720314947
Sep 2020
www.sciencedirect.com www.sciencedirect.com

Diverse CD8 T Cell Responses to Viral Infection Revealed by the Collaborative Cross

1
1. scibot 26 Sep 2020
  
  in Public
  
  RRID:AB_469410
  
  DOI: 10.1016/j.celrep.2020.03.072
  
  Resource: (Thermo Fisher Scientific Cat# 17-0621-82, RRID:AB_469410)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_469410
  
  What is this?
  
  RRIDCUR:Validated RRID:AB_469410
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_469410

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124720303983
www.cell.com www.cell.com

A Stat6/Pten Axis Links Regulatory T Cells with Adipose Tissue Function

1
1. scibot 10 Sep 2020
  
  in Public
  
  RRID:AB_469410
  
  DOI: 10.1016/j.cmet.2017.08.008
  
  Resource: (Thermo Fisher Scientific Cat# 17-0621-82, RRID:AB_469410)
  
  Curator: @evieth
  
  SciCrunch record: RRID:AB_469410
  
  What is this?
  
  RRIDCUR:Validated RRID:AB_469410
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_469410

Annotators

scibot

URL

cell.com/cell-metabolism/abstract/S1550-4131(17)30493-X
Jan 2020
www.sciencedirect.com www.sciencedirect.com

Untitled document

1
1. scibot 13 Jan 2020
  
  in Public
  
  AB_469410
  
  DOI: 10.1016/j.immuni.2018.12.016
  
  Resource: (Thermo Fisher Scientific Cat# 17-0621-82, RRID:AB_469410)
  
  Curator: @ethanbadger
  
  SciCrunch record: AB_469410
  
  What is this?
  
  RRID:AB_469410 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_469410

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1074761318305648
www.sciencedirect.com www.sciencedirect.com

A Neutrophil Timer Coordinates Immune Defense and Vascular Protection

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_469410
  
  DOI: 10.1016/j.immuni.2019.01.002
  
  Resource: (Thermo Fisher Scientific Cat# 17-0621-82, RRID:AB_469410)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_469410
  
  What is this?
  
  RRID:AB_469410 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_469410

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1074761319300020
Nov 2018
www.sciencedirect.com www.sciencedirect.com

B Cells Are the Dominant Antigen-Presenting Cells that Activate Naive CD4+ T Cells upon Immunization with a Virus-Derived Nanoparticle Antigen

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:AB_469410
  
  Curator: @Jmenke
  
  Resource used:
  
  (Thermo Fisher Scientific Cat# 17-0621-82, RRID:AB_469410)
  
  SciCrunch record: RRID:AB_469410
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_469410 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_469410

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1074761318303534
Nov 2017
www.sciencedirect.com www.sciencedirect.com

A Predictive Model for Selective Targeting of the Warburg Effect through GAPDH Inhibition with a Natural Product

1
1. scibot 08 Nov 2017
  
  in Public
  
  RRID:AB_469410
  
  Curator: @Jmenke
  
  Resource used:
  
  (Thermo Fisher Scientific Cat# 17-0621-82, RRID:AB_469410)
  
  SciCrunch record: RRID:AB_469410
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_469410 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_469410

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1550413117305028
www.sciencedirect.com www.sciencedirect.com

A Stat6/Pten Axis Links Regulatory T Cells with Adipose Tissue Function

1
1. scibot 08 Nov 2017
  
  in Public
  
  RRID:AB_469410
  
  Curator: @Jmenke
  
  Resource used:
  
  (Thermo Fisher Scientific Cat# 17-0621-82, RRID:AB_469410)
  
  SciCrunch record: RRID:AB_469410
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_469410 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_469410

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S155041311730493X
www.sciencedirect.com www.sciencedirect.com

Cholesterol Accumulation in Dendritic Cells Links the Inflammasome to Acquired Immunity

1
1. scibot 08 Nov 2017
  
  in Public
  
  AB_469410
  
  Curator: @gabimpine
  
  Resource used:
  
  (Thermo Fisher Scientific Cat# 17-0621-82, RRID:AB_469410)
  
  SciCrunch record: RRID:AB_469410
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_469410 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_469410

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1550413117302103