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SENP1 facilitates the adaptation of colonic non-lymphoid tissue Treg cells and restrains intestinal inflammation

1
1. scibot 19 May 2026
  
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  RRID:AB_469457
  
  DOI: 10.1016/j.mucimm.2026.100349
  
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sciencedirect.com/science/article/pii/S1933021926000516
May 2026
www-cell-com.eproxy.lib.hku.hk www-cell-com.eproxy.lib.hku.hk

Whole-genome doubling drives immune evasion by silencing antigen presentation

1
1. scibot 08 May 2026
  
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  DOI: 10.1016/j.ccell.2026.04.007
  
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www-cell-com.eproxy.lib.hku.hk/cancer-cell/fulltext/S1535-6108(26)00218-7
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Tissue-specific tolerance mechanisms and lymph node co-drainage shape T cell immunity in the upper digestive system and pancreatic cancer progression

1
1. scibot 07 May 2026
  
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  RRID:AB_469457
  
  DOI: 10.1016/j.celrep.2026.117324
  
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sciencedirect.com/science/article/pii/S221112472600402X
aacrjournals.org aacrjournals.org

IL-1R2 Deficiency Unleashes Neutrophil-Mediated Antitumor Potential in Sarcoma

1
1. scibot 05 May 2026
  
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  RRID:AB_469457
  
  DOI: 10.1158/2326-6066.CIR-25-0651
  
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aacrjournals.org/cancerimmunolres/article/14/5/751/784456/IL1R2-Deficiency-Unleashes-Neutrophil-Mediated
Apr 2026
54.241.53.176 54.241.53.176

1-s2.0-S2589004226011764-main-html.html

1
1. scibot 22 Apr 2026
  
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  RRID:AB_469457
  
  DOI: 10.1016/j.isci.2026.115801
  
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54.241.53.176/8488015b440db33861248d6c24369f9587bf2f0a/1-s2.0-S2589004226011764-main-html.html
54.241.53.176 54.241.53.176

cs-2025-7273-supp1-html.html

1
1. scibot 03 Apr 2026
  
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  AB_469457
  
  DOI: 10.1042/CS20257273
  
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54.241.53.176/5157d7efdcceb98e832fa150b25ddfec409cd84d/cs-2025-7273-supp1-html.html
Mar 2026
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A hierarchical Rorc(γt) cis-regulatory cascade orchestrates differentiation of RORγt⁺ innate immune cells

1
1. scibot 26 Mar 2026
  
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  RRID:AB_469457
  
  DOI: 10.1016/j.immuni.2026.02.002
  
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sciencedirect.com/science/article/pii/S1074761326000543
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Tissue and CD4 T cell subset dependence on the amino acid transporter SLC38A1

1
1. scibot 24 Mar 2026
  
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  RRID:AB_469457
  
  DOI: 10.1016/j.cmet.2026.02.016
  
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sciencedirect.com/science/article/pii/S1550413126000859
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Dnmt3a-dependent de novo DNA methylation enforces lineage commitment and preserves functionality of memory Th1 and Tfh cells

1
1. scibot 17 Mar 2026
  
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  RRID:AB_469457
  
  DOI: 10.1016/j.celrep.2026.117062
  
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sciencedirect.com/science/article/pii/S2211124726001403
Feb 2026
54.241.53.176 54.241.53.176

cs-2025-7273-supp1-html.html

1
1. scibot 26 Feb 2026
  
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  AB_469457
  
  DOI: 10.1042/CS20257273
  
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54.241.53.176/6d9933fde27ce59d29734a87c774248b753cab90/cs-2025-7273-supp1-html.html
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Microbial activation of the GLP-2R mitigates gastrointestinal inflammation

1
1. scibot 25 Feb 2026
  
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  RRID:AB_469457
  
  DOI: 10.1038/s41467-026-68551-9
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12920917/
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Cytosolic DNA structures produced by mismatch repair deficiency coordinate anti-tumor immunity in colorectal cancer

1
1. scibot 20 Feb 2026
  
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  RRID:AB_469457
  
  DOI: 10.1016/j.celrep.2026.117012
  
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sciencedirect.com/science/article/pii/S2211124726000902
Jan 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Photo‐Empowered Macrophage‐Based Drug Delivery System Overcomes Motility Suppression and Significantly Enhances Deep Tumor Drug Delivery

1
1. scibot 30 Jan 2026
  
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  RRID:AB_469
  
  DOI: 10.1002/advs.202515349
  
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  Curator: @evieth
  
  SciCrunch record: RRID:AB_469457
  
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  RRIDCUR:Unresolved RRID:AB_469457
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pmc.ncbi.nlm.nih.gov/articles/PMC12850126/
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Fibroblast-derived alarmin promotes oral wound healing by activating regulatory T cells that relay pro-angiogenic and anti-inflammatory responses

1
1. scibot 15 Jan 2026
  
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  RRID:AB_469457
  
  DOI: 10.1016/j.celrep.2025.116829
  
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sciencedirect.com/science/article/pii/S2211124725016018
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MITA/STING-driven CD38 induction in Siglec-Flow macrophages promotes regulatory T cell survival and non-small cell lung cancer progression

1
1. scibot 13 Jan 2026
  
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  RRID:AB_469457
  
  DOI: 10.1016/j.devcel.2025.12.007
  
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sciencedirect.com/science/article/pii/S1534580725007683
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IgG2c subclass dominance drives fatal lupus-like nephritis via FcγR and complement activation

1
1. scibot 09 Jan 2026
  
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  RRID:AB_469457
  
  DOI: 10.1016/j.celrep.2025.116775
  
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sciencedirect.com/science/article/pii/S2211124725015475
Dec 2025
www.sciencedirect.com:5037 www.sciencedirect.com:5037

Positioning and reversible suppression of CCR7+ dendritic cells in perivascular tumor niches shape cancer immunity

1
1. scibot 20 Dec 2025
  
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  RRID:AB_469457
  
  DOI: 10.1016/j.immuni.2025.11.020
  
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sciencedirect.com:5037/science/article/pii/S1074761325005229
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ARAP2 regulates responses to interferon-gamma by restricting SOCS1

1
1. scibot 16 Dec 2025
  
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  RRID:AB_469457
  
  DOI: 10.1016/j.celrep.2025.116667
  
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sciencedirect.com:5037/science/article/pii/S2211124725014391
Nov 2025
54.241.53.176 54.241.53.176

2025.11.06.687030v2.full-html.html

1
1. scibot 13 Nov 2025
  
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  RRID:AB_469457
  
  DOI: 10.1101/2025.11.06.687030
  
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54.241.53.176/61ff3c01c4fabc7d4036cd8525cf0aefcb431dbf/2025.11.06.687030v2.full-html.html
Oct 2025
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Treg-microglia partnership in the injured spinal cord preserves Treg cell function and regulates microglial cholesterol metabolism

1
1. scibot 01 Oct 2025
  
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  RRID:AB_469457
  
  DOI: 10.1016/j.neuron.2025.09.001
  
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sciencedirect.com/science/article/pii/S0896627325006671
Sep 2025
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Gut microbe-derived metabolites drive psoriatic inflammation via modulation of skin Th17 cells

1
1. scibot 11 Sep 2025
  
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  RRID:AB_469457
  
  DOI: 10.1016/j.immuni.2025.08.006
  
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sciencedirect.com/science/article/pii/S1074761325003693
Aug 2025
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A capsular polysaccharide from a healthy human microbiota member activates a Lag-3-NK cell axis to restrain colon cancer and augment immunotherapy

1
1. scibot 26 Aug 2025
  
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  RRID:AB_469457
  
  DOI: 10.1016/j.celrep.2025.116172
  
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sciencedirect.com/science/article/pii/S221112472500943X
www.tandfonline.com www.tandfonline.com

A preclinical model for the identification of therapeutically active transgenes in local cancer immunotherapy

1
1. scibot 21 Aug 2025
  
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  RRID:AB_469457
  
  DOI: 10.1080/2162402X.2025.2543620
  
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tandfonline.com/doi/full/10.1080/2162402X.2025.2543620
onlinelibrary.wiley.com onlinelibrary.wiley.com

The absence of IL17A favours cytotoxic cell function and improves antigen-specific immunotherapies in pancreatic adenocarcinoma

1
1. scibot 21 Aug 2025
  
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  RRID:AB_469457
  
  DOI: 10.1002/ctm2.70442
  
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onlinelibrary.wiley.com/doi/10.1002/ctm2.70442
Jul 2025
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Antibody-mediated TGF-β1 activation for the treatment of diseases caused by deleterious T cell activity

1
1. scibot 30 Jul 2025
  
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  RRID:AB_469457
  
  DOI: 10.1016/j.celrep.2025.116061
  
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sciencedirect.com/science/article/pii/S2211124725008320
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Structure of gut microbial glycolipid modulates host inflammatory response

1
1. scibot 23 Jul 2025
  
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  RRID:AB_469457
  
  DOI: 10.1016/j.cell.2025.05.016
  
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sciencedirect.com/science/article/pii/S0092867425005665
www.mdpi.com www.mdpi.com

IL-2 Complex Therapy Mitigates Humoral Rejection of Fully Mismatched Skin Allografts by Inhibiting IgG Alloantibody Formation

1
1. scibot 22 Jul 2025
  
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  RRID:AB_469457
  
  DOI: 10.3390/cells14141086
  
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mdpi.com/2073-4409/14/14/1086
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Transmission of maternal oral pathobionts to the infant gut predisposes offspring to exacerbated enteritis

1
1. scibot 17 Jul 2025
  
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  RRID:AB_469457
  
  DOI: 10.1016/j.celrep.2025.115974
  
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sciencedirect.com/science/article/pii/S2211124725007454
Jun 2025
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A first-in-class EGFR-directed KRAS G12V selective inhibitor

1
1. scibot 21 Jun 2025
  
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  RRID:AB_469457
  
  DOI: 10.1016/j.ccell.2025.05.016
  
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sciencedirect.com/science/article/pii/S1535610825002259
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The IL-33/ST2 axis and tissue Treg maintain epithelial homeostasis and restrain cancer development in the skin

1
1. scibot 17 Jun 2025
  
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  DOI: 10.1016/j.celrep.2025.115837
  
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sciencedirect.com/science/article/pii/S2211124725006084
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Fc-optimized anti-CTLA-4 antibodies increase tumor-associated high endothelial venules and sensitize refractory tumors to PD-1 blockade

1
1. scibot 04 Jun 2025
  
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  RRID:AB_469457
  
  DOI: 10.1016/j.xcrm.2025.102141
  
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sciencedirect.com/science/article/pii/S2666379125002149
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The role of Tim-3+T cell subsets in the peripheral blood of patients with COVID-19 and diabetes

1
1. scibot 18 May 2025
  
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  RRID:AB_469457
  
  DOI: 10.1016/j.isci.2025.112339
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12053769/
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Interferon-γ and IL-27 positively regulate type 1 regulatory T cell development during adaptive tolerance

1
1. scibot 18 May 2025
  
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  RRID:AB_469457
  
  DOI: 10.1016/j.isci.2025.112308
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12018090/
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IL-10 sensing by lung interstitial macrophages prevents bacterial dysbiosis-driven pulmonary inflammation and maintains immune homeostasis

1
1. scibot 17 May 2025
  
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  RRID:AB_469457
  
  DOI: 10.1016/j.immuni.2025.04.004
  
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sciencedirect.com/science/article/pii/S1074761325001670
Apr 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

CXXC-finger protein 1 associates with FOXP3 to stabilize homeostasis and suppressive functions of regulatory T cells

1
1. scibot 08 Apr 2025
  
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  RRID:AB_469457
  
  DOI: 10.7554/eLife.103417
  
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Soluble CTLA-4 regulates immune homeostasis and promotes resolution of inflammation by suppressing type 1 but allowing type 2 immunity

1
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  RRID:AB_469457
  
  DOI: 10.1016/j.immuni.2025.03.004
  
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sciencedirect.com/science/article/pii/S1074761325001232
Mar 2025
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Interferon-γ-stimulated antigen-presenting cancer-associated fibroblasts hinder neoadjuvant chemoimmunotherapy efficacy in lung cancer

1
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  RRID:AB_469457
  
  DOI: 10.1016/j.xcrm.2025.102017
  
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Low-dose irradiation of the gut improves the efficacy of PD-L1 blockade in metastatic cancer patients

1
1. scibot 11 Mar 2025
  
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  RRID:AB_469457
  
  DOI: 10.1016/j.ccell.2025.02.010
  
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Feb 2025
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NFAT single-deficient murine T cells reduce the risk of aGvHD while controlling cytomegalovirus infection

1
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  RRID:AB_469457
  
  DOI: 10.1016/j.isci.2025.111937
  
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Inositol polyphosphate multikinase regulates Th1 and Th17 cell differentiation by controlling Akt-mTOR signaling

1
1. scibot 13 Feb 2025
  
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  RRID:AB_469457
  
  DOI: 10.1016/j.celrep.2025.115281
  
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MFGE8 induces anti-PD-1 therapy resistance by promoting extracellular vesicle sorting of PD-L1

1
1. scibot 23 Jan 2025
  
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  RRID:AB_469457
  
  DOI: 10.1016/j.xcrm.2024.101922
  
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Targeting the mevalonate pathway potentiates NUAK1 inhibition-induced immunogenic cell death and antitumor immunity

1
1. scibot 17 Jan 2025
  
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  RRID:AB_469457
  
  DOI: 10.1016/j.xcrm.2024.101913
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11866496/
Dec 2024
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Mechanism of enhancing chemotherapy efficacy in pancreatic ductal adenocarcinoma with paricalcitol and hydroxychloroquine

1
1. scibot 29 Dec 2024
  
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  RRID:AB_469457
  
  DOI: 10.1016/j.xcrm.2024.101881
  
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cell.com/cell-reports-medicine/fulltext/S2666-3791(24)00652-9
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Protocol for murine multi-tissue deep immunophenotyping using a 40-color full-spectrum flow cytometry panel

1
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  DOI: 10.1016/j.xpro.2024.103492
  
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A double-edged sword role of IFN-γ producing iNKT cells in sepsis: persistent suppression of Treg cell formation in a Nr4a1 dependent manner

1
1. scibot 14 Dec 2024
  
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  RRID:AB_469457
  
  DOI: 10.1016/j.isci.2024.111462
  
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Prenatal antibiotics reduce breast milk IgA and induce dysbiosis in mouse offspring, increasing neonatal susceptibility to bacterial sepsis

1
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  AB_469457
  
  DOI: 10.1016/j.chom.2024.11.001
  
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sciencedirect.com/science/article/pii/S1931312824004074
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Leader cells promote immunosuppression to drive ovarian cancer progression in vivo

1
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  DOI: 10.1016/j.celrep.2024.114979
  
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sciencedirect.com/science/article/pii/S2211124724013305
Sep 2024
www-cell-com.utokyo.idm.oclc.org www-cell-com.utokyo.idm.oclc.org

Analysis of T cells in mouse lymphoid tissue and blood with flow cytometry

1
1. scibot 25 Sep 2024
  
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  RRID:AB_469456
  
  DOI: 10.1016/j.xpro.2021.100351
  
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www-cell-com.utokyo.idm.oclc.org/star-protocols/fulltext/S2666-1667(21)00058-7
Jul 2024
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Lymphatic-localized Treg-mregDC crosstalk limits antigen trafficking and restrains anti-tumor immunity

1
1. scibot 25 Jul 2024
  
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  AB_469457
  
  DOI: 10.1016/j.ccell.2024.06.014
  
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Lack of canonical thyroid hormone receptor α signaling changes regulatory T cell phenotype in female mice

1
1. scibot 25 Jul 2024
  
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  RRID:AB_469457
  
  DOI: 10.1016/j.isci.2024.110547
  
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52.53.155.43/ec8bf473a95e0f0a14821b5e61884b766010f004/1-s2.0-S2589004224017723-main-html.html
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Protection from environmental enteric dysfunction and growth improvement in malnourished newborns by amplification of secretory IgA

1
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  AB_469457
  
  DOI: 10.1016/j.xcrm.2024.101639
  
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Protocol to study the immune profile of syngeneic mouse tumor models

1
1. scibot 14 Jul 2024
  
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  RRID:AB_469457
  
  DOI: 10.1016/j.xpro.2024.103139
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11234017/
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SWI/SNF chromatin remodeling factor BAF60b restrains inflammatory diseases by affecting regulatory T cell migration

2
1. scibot 12 Jul 2024
  
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  RRID:AB_469457
  
  DOI: 10.1016/j.celrep.2024.114458
  
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  RRID:AB_469457
  
  DOI: 10.1016/j.celrep.2024.114458
  
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sciencedirect.com/science/article/pii/S2211124724007873
Jun 2024
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Clonal hematopoiesis driven by mutated DNMT3A promotes inflammatory bone loss

1
1. scibot 05 Jun 2024
  
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  RRID:AB_469457
  
  DOI: 10.1016/j.cell.2024.05.003
  
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sciencedirect.com/science/article/pii/S0092867424004926
May 2024
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A RIPK1-specific PROTAC degrader achieves potent antitumor activity by enhancing immunogenic cell death

1
1. scibot 24 May 2024
  
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  RRID:AB_469457
  
  DOI: 10.1016/j.immuni.2024.04.025
  
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sciencedirect.com/science/article/pii/S1074761324002309
Apr 2024
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CD80 on skin stem cells promotes local expansion of regulatory T cells upon injury to orchestrate repair within an inflammatory environment

1
1. scibot 30 Apr 2024
  
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  RRID:AB_469457
  
  DOI: 10.1016/j.immuni.2024.04.003
  
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sciencedirect.com/science/article/pii/S1074761324002085
Mar 2024
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Adipose stem cells control obesity-induced T cell infiltration into adipose tissue

1
1. scibot 19 Mar 2024
  
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  RRID:AB_469457
  
  DOI: 10.1016/j.celrep.2024.113963
  
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NR4a1/2 deletion promotes accumulation of TCF1+ stem-like precursors of exhausted CD8+ T cells in the tumor microenvironment

2
1. scibot 06 Mar 2024
  
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  RRID:AB_469457
  
  DOI: 10.1016/j.celrep.2024.113898
  
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  RRID:AB_469457
  
  DOI: 10.1016/j.celrep.2024.113898
  
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sciencedirect.com/science/article/pii/S2211124724002262
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FcγRIIB is an immune checkpoint limiting the activity of Treg-targeting antibodies in the tumor microenvironment

1
1. scibot 06 Mar 2024
  
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  RRID:AB_469457
  
  DOI: 10.1158/2326-6066.CIR-23-0389
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10911703/
Feb 2024
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Lactate modulates RNA splicing to promote CTLA-4 expression in tumor-infiltrating regulatory T cells

2
1. scibot 29 Feb 2024
  
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  RRID:AB_469457
  
  DOI: 10.1016/j.immuni.2024.01.019
  
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  RRID:AB_469457
  
  DOI: 10.1016/j.immuni.2024.01.019
  
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sciencedirect.com/science/article/pii/S1074761324000451
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The CD27/CD70 pathway negatively regulates visceral adipose tissue-resident Th2 cells and controls metabolic homeostasis

1
1. scibot 22 Feb 2024
  
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  DOI: 10.1016/j.celrep.2024.113824
  
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sciencedirect.com/science/article/pii/S2211124724001529
Dec 2023
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Oral tolerance to systemic vaccination remains intact without RORγt expression in regulatory T cells

1
1. scibot 21 Dec 2023
  
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  RRID:AB_469457
  
  DOI: 10.1016/j.isci.2023.108504
  
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De novo NAD+ synthesis contributes to CD8+ T cell metabolic fitness and antitumor function

1
1. scibot 21 Dec 2023
  
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  RRID:AB_469457
  
  DOI: 10.1016/j.celrep.2023.113518
  
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Reprogramming of tumor-associated macrophages via NEDD4-mediated CSF1R degradation by targeting USP18

1
1. scibot 17 Dec 2023
  
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  RRID:AB_469457
  
  DOI: 10.1016/j.celrep.2023.113560
  
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Nov 2023
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An engineered immunocytokine with collagen affinity improves the tumor bioavailability, tolerability, and therapeutic efficacy of IL-2

1
1. scibot 22 Nov 2023
  
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  RRID:AB_469457
  
  DOI: 10.1016/j.xcrm.2023.101289
  
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An essential role for miR-15/16 in Treg suppression and restriction of proliferation

1
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  DOI: 10.1016/j.celrep.2023.113298
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10664750/
Oct 2023
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Unedited allogeneic iNKT cells show extended persistence in MHC-mismatched canine recipients

1
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  RRID:AB_469457
  
  DOI: 10.1016/j.xcrm.2023.101241
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10591065/
Aug 2023
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Tumor-associated macrophages trigger MAIT cell dysfunction at the HCC invasive margin

1
1. scibot 29 Aug 2023
  
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  RRID:AB_469457
  
  DOI: 10.1016/j.cell.2023.07.026
  
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52.53.155.43 52.53.155.43

CD39 inhibition and VISTA blockade may overcome radiotherapy resistance by targeting exhausted CD8+ T cells and immunosuppressive myeloid cells

2
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SOCS3 deletion in effector T cells confers an anti-tumorigenic role of IL-6 to the pro-tumorigenic cytokine

2
1. scibot 17 Aug 2023
  
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  DOI: 10.1016/j.celrep.2023.112940
  
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Tumoral P2Y2 receptor modulates tumor growth and host anti-tumor immune responses in a syngeneic murine model of oral cancer

1
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Original research: Defining the spatial distribution of extracellular adenosine revealed a myeloid-dependent immunosuppressive microenvironment in pancreatic ductal adenocarcinoma

1
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crc-22-0293-html.html

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  DOI: 10.1158/2767-9764.crc-22-0293
  
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Jun 2023
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Prolonged dysbiosis and altered immunity under nutritional intervention in a physiological mouse model of severe acute malnutrition

1
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  DOI: 10.1016/j.isci.2023.106910
  
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May 2023
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Co-modulation of TNFR1 and TNFR2 in an animal model of multiple sclerosis

1
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  DOI: 10.1186/s12974-023-02784-z
  
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Apr 2023
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Gut dysbiosis promotes the breakdown of oral tolerance mediated through dysfunction of mucosal dendritic cells

1
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The gut microbiota promotes distal tissue regeneration via RORγ+ regulatory T cell emissaries

1
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Mechanism of inert inflammation in an immune checkpoint blockade-resistant tumor subtype bearing transcription elongation defects

1
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Long-term tolerance to skin commensals is established neonatally through a specialized dendritic cell subgroup

1
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Mar 2023
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Arresting microbiome development limits immune system maturation and resistance to infection in mice

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  DOI: 10.1016/j.chom.2023.03.006
  
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Crosstalk between microbiome, regulatory T cells and HCA2 orchestrates the inflammatory response in a murine psoriasis model

1
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  DOI: 10.3389/fimmu.2023.1038689
  
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Pyruvate dehydrogenase fuels a critical citrate pool that is essential for Th17 cell effector functions

1
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Feb 2023
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DRAK2 contributes to type 1 diabetes by negatively regulating IL-2 sensitivity to alter regulatory T cell development

1
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  DOI: 10.1016/j.celrep.2023.112106
  
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Loss of C3a and C5a receptors promotes adipocyte browning and attenuates diet-induced obesity via activating inosine/A2aR pathway

1
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Nov 2022
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Engineered human cytokine/antibody fusion proteins expand regulatory T cells and confer autoimmune disease protection

1
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The ketone body β-hydroxybutyrate mitigates ILC2-driven airway inflammation by regulating mast cell function

1
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The matricellular protein SPARC induces inflammatory interferon-response in macrophages during aging

1
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Optimal target saturation of ligand-blocking anti-GITR antibody IBI37G5 dictates FcγR-independent GITR agonism and antitumor activity

1
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PGE2-EP2/EP4 signaling elicits immunosuppression by driving the mregDC-Treg axis in inflammatory tumor microenvironment

1
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Mitochondrial damage-associated molecular patterns trigger arginase-dependent lymphocyte immunoregulation

1
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Interleukin-6 blockade abrogates immunotherapy toxicity and promotes tumor immunity

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Mar 2022
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Activation of regulatory T cells triggers specific changes in glycosylation associated with Siglec-1-dependent inflammatory responses

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  DOI: 10.12688/wellcomeopenres.16834.1
  
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Activating Mucosal-Associated Invariant T cells Induces a Broad Antitumor Response

1
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  DOI: 10.1158/2326-6066.CIR-20-0925
  
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Feb 2022
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Mucosal fungi promote gut barrier function and social behavior via Type 17 immunity

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Tumor-associated high endothelial venules mediate lymphocyte entry into tumors and predict response to PD-1 plus CTLA-4 combination immunotherapy

1
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Jan 2022
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Magnesium sensing via LFA-1 regulates CD8+ T cell effector function

1
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  DOI: 10.1016/j.cell.2021.12.039
  
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Adenosine 2A receptor and TIM3 suppress cytolytic killing of tumor cells via cytoskeletal polarization

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  DOI: 10.1038/s42003-021-02972-8
  
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nature.com/articles/s42003-021-02972-8
Dec 2021
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GPR120 induces regulatory dendritic cells by inhibiting HK2-dependent glycolysis to alleviate fulminant hepatic failure

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  DOI: 10.1038/s41419-021-04394-0
  
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Induction of Foxp3 and activation of Tregs by HSP gp96 for treatment of autoimmune diseases

1
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  DOI: 10.1016/j.isci.2021.103445
  
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Maternal gut bacteria drive intestinal inflammation in offspring with neurodevelopmental disorders by altering the chromatin landscape of CD4+ T cells

1
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  DOI: 10.1016/j.immuni.2021.11.005
  
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Nov 2021
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Systemic delivery of a targeted synthetic immunostimulant transforms the immune landscape for effective tumor regression

1
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  DOI: 10.1016/j.chembiol.2021.10.012
  
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MTHFD2 is a metabolic checkpoint controlling effector and regulatory T cell fate and function

1
1. scibot 12 Nov 2021
  
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  DOI: 10.1016/j.immuni.2021.10.011
  
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Graded RhoA GTPase Expression in Treg Cells Distinguishes Tumor Immunity From Autoimmunity

1
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  DOI: 10.3389/fimmu.2021.726393
  
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Epithelial-myeloid exchange of MHC class II constrains immunity and microbiota composition

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Effector T cell responses unleashed by regulatory T cell ablation exacerbate oral squamous cell carcinoma

1
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Redundant cytokine requirement for intestinal microbiota-induced Th17 cell differentiation in draining lymph nodes

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ADAR1 interaction with Z-RNA promotes editing of endogenous double-stranded RNA and prevents MDA5-dependent immune activation

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Sex and Gender in Renal Health and Function: Hypertensive female Sprague-Dawley rats require an intact nitric oxide synthase system for compensatory increases in renal regulatory T cells

1
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  DOI: 10.1152/ajprenal.00228.2020
  
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Untitled document

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  DOI: 10.1016/j.chom.2018.11.003
  
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The Microbial Metabolite Butyrate Stimulates Bone Formation via T Regulatory Cell-Mediated Regulation of WNT10B Expression

1
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Antibodies to Costimulatory Receptor 4-1BB Enhance Anti-tumor Immunity via T Regulatory Cell Depletion and Promotion of CD8 T Cell Effector Function

1
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  DOI: 10.1016/j.immuni.2018.09.014
  
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Untitled document

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  DOI: 10.1038/s41598-018-31957-7
  
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Colitis-Induced Th17 Cells Increase the Risk for Severe Subsequent Clostridium difficile Infection

2
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  DOI: 10.1016/j.chom.2019.03.003
  
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Untitled document

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Response to Fungal Dysbiosis by Gut Resident CX3CR1+ Mononuclear Phagocytes Aggravates Allergic Airway Disease

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A safe and effective mucosal RSV vaccine in mice consisting of RSV phosphoprotein and flagellin variant

1
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Interferon-α-producing plasmacytoid dendritic cells drive the loss of adipose tissue regulatory T cells during obesity

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Expansion of tumor-associated Treg cells upon disruption of a CTLA-4-dependent feedback loop

1
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  DOI: 10.1016/j.cell.2021.05.027
  
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Aging-associated deficit in CCR7 is linked to worsened glymphatic function, cognition, neuroinflammation, and β-amyloid pathology

1
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Calibration of cell-intrinsic interleukin-2 response thresholds guides design of a regulatory T cell biased agonist

1
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  Anti-mouse Foxp3 APC (FJK-16S) rat monoclonal
  
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Treg cell-derived osteopontin promotes microglia-mediated white matter repair after ischemic stroke

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In vivo screens using a selective CRISPR antigen removal lentiviral vector system reveal immune dependencies in renal cell carcinoma

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The Conserved Non-coding Sequences CNS6 and CNS9 Control Cytokine-Induced Rorc Transcription during T Helper 17 Cell Differentiation

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T Cell Receptor Is Required for Differentiation, but Not Maintenance, of Intestinal CD4+ Intraepithelial Lymphocytes

1
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Distinct Foxp3 enhancer elements coordinate development, maintenance, and function of regulatory T cells

1
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Enteric viruses evoke broad host immune responses resembling those elicited by the bacterial microbiome

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The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis

1
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Single-cell chromatin accessibility landscape identifies tissue repair program in human regulatory T cells

1
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The kinase PDK1 is critical for promoting T follicular helper cell differentiation

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  DOI: 10.7554/eLife.61406
  
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Murine model of colonization with fungal pathogen Candida auris to explore skin tropism, host risk factors and therapeutic strategies

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cell.com/cell-host-microbe/abstract/S1931-3128(20)30664-8
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A Booster Dose Enhances Immunogenicity of the COVID-19 Vaccine Candidate ChAdOx1 nCoV-19 in Aged Mice

1
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Targeting Phosphatidylserine Enhances the Anti-tumor Response to Tumor-Directed Radiation Therapy in a Preclinical Model of Melanoma

1
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Microbiota-Derived Metabolites Suppress Arthritis by Amplifying Aryl-Hydrocarbon Receptor Activation in Regulatory B Cells

1
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Glutathione Restricts Serine Metabolism to Preserve Regulatory T Cell Function

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  DOI: 10.1016/j.cmet.2020.03.004
  
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Checkpoint Receptor TIGIT Expressed on Tim-1+ B Cells Regulates Tissue Inflammation

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  DOI: 10.1016/j.celrep.2020.107892
  
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An Immunologic Mode of Multigenerational Transmission Governs a Gut Treg Setpoint

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  DOI: 10.1016/j.cell.2020.04.030
  
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Discovery of surrogate agonists for visceral fat Treg cells that modulate metabolic indices in vivo

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  DOI: 10.7554/eLife.58463
  
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Heparin affects the induction of regulatory T cells independent of anticoagulant activity and suppresses the allogeneic immune responses

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Hypertensive female Sprague-Dawley rats require an intact nitric oxide synthase system for compensatory increases in renal regulatory T cells | American Journal of Physiology-Renal Physiology

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Aging Induces an Nlrp3 Inflammasome-Dependent Expansion of Adipose B Cells That Impairs Metabolic Homeostasis

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miR-15/16 Restrain Memory T Cell Differentiation, Cell Cycle, and Survival

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  DOI: 10.1016/j.celrep.2019.07.064
  
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Aryl Hydrocarbon Receptor Contributes to the Transcriptional Program of IL-10-Producing Regulatory B Cells

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  DOI: 10.1016/j.celrep.2019.10.018
  
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Acylglycerol Kinase Maintains Metabolic State and Immune Responses of CD8+ T Cells

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  DOI: 10.1016/j.cmet.2019.05.016
  
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The Transcription Factor MAZR/PATZ1 Regulates the Development of FOXP3+ Regulatory T Cells

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Interleukin-27 Is Essential for Type 1 Diabetes Development and Sjögren Syndrome-like Inflammation

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Pharmacological Activation of Pyruvate Kinase M2 Inhibits CD4+ T Cell Pathogenicity and Suppresses Autoimmunity

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  DOI: 10.1016/j.cmet.2019.10.015
  
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TCF1 and LEF1 Control Treg Competitive Survival and Tfr Development to Prevent Autoimmune Diseases

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Colitis-Induced Th17 Cells Increase the Risk for Severe Subsequent Clostridium difficile Infection

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  DOI: 10.1016/j.chom.2019.03.003
  
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Blocking Antibodies Targeting the CD39/CD73 Immunosuppressive Pathway Unleash Immune Responses in Combination Cancer Therapies

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cell.com/cell-reports/fulltext/S2211-1247(19)30571-6
Nov 2018
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Blimp-1 Functions as a Molecular Switch to Prevent Inflammatory Activity in Foxp3+RORγt+ Regulatory T Cells

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Untitled document

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IKZF1 Enhances Immune Infiltrate Recruitment in Solid Tumors and Susceptibility to Immunotherapy

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Autoimmune Th17 Cells Induced Synovial Stromal and Innate Lymphoid Cell Secretion of the Cytokine GM-CSF to Initiate and Augment Autoimmune Arthritis

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CD150high Bone Marrow Tregs Maintain Hematopoietic Stem Cell Quiescence and Immune Privilege via Adenosine

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KLRG1+ Effector CD8+ T Cells Lose KLRG1, Differentiate into All Memory T Cell Lineages, and Convey Enhanced Protective Immunity

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White Adipose Tissue Is a Reservoir for Memory T Cells and Promotes Protective Memory Responses to Infection

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Analyses of a Mutant Foxp3 Allele Reveal BATF as a Critical Transcription Factor in the Differentiation and Accumulation of Tissue Regulatory T Cells

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