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Genotoxicity profiling reveals distinct platform-and cell type-specific effects in therapeutic gene editing for genetic hyperinflammation

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1. scibot 14 May 2026
  
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  DOI: 10.1016/j.stem.2026.04.014
  
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sciencedirect.com/science/article/pii/S1934590926001542
May 2026
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Cohesin complex cooperates with PU.1 at super-enhancers to regulate the differentiation and identity of conventional dendritic cells

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1. scibot 07 May 2026
  
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  DOI: 10.1016/j.celrep.2026.117331
  
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sciencedirect.com/science/article/pii/S2211124726004092
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Newly isolated human-derived Lactobacillus fermentum strain stimulates IFN-γ-secreting CD8+ T cells for enhanced anti-cancer immunity

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1. scibot 01 May 2026
  
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  DOI: 10.1016/j.isci.2026.115642
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13125905/
Mar 2026
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Disruption of WNT/Notch signaling in pancreatic cancer reveals tumors depend on the intricate equilibrium of malignant cell states

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1. scibot 24 Mar 2026
  
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  DOI: 10.1016/j.devcel.2026.02.017
  
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sciencedirect.com/science/article/pii/S1534580726000821
Feb 2026
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Effector differentiation by stem-like intraepithelial γδ T cells is required for host defense against infection

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1. scibot 26 Feb 2026
  
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  DOI: 10.1016/j.immuni.2026.01.006
  
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sciencedirect.com/science/article/pii/S1074761326000270
Dec 2025
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Neutrophils, not macrophages, aid phage-mediated control of pulmonary Pseudomonas aeruginosa infection

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1. scibot 05 Dec 2025
  
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  DOI: 10.3389/fimmu.2025.1681461
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12672430/
Nov 2025
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Glucose tasting depletes intracellular calcium stores and impairs macrophage functionality

1
1. scibot 19 Nov 2025
  
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  DOI: 10.1016/j.isci.2025.113770
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12616019/
Oct 2025
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Midbrain degeneration triggers astrocyte reactivity and tau pathology in experimental Alzheimer’s Disease

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1. scibot 16 Oct 2025
  
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  DOI: 10.1186/s13024-025-00893-2
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12516900/
Sep 2025
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GATA2 decommissioning of enhancers: A mechanism to constrain inflammatory signaling

1
1. scibot 25 Sep 2025
  
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  DOI: 10.1016/j.celrep.2025.116344
  
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sciencedirect.com/science/article/pii/S2211124725011155
52.53.155.43 52.53.155.43

1-s2.0-S2589004225017985-main-html.html

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1. scibot 16 Sep 2025
  
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  RRID:AB_469588
  
  DOI: 10.1016/j.isci.2025.113537
  
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52.53.155.43/bfa103a56e03ca8260532bade686a824030c14b2/1-s2.0-S2589004225017985-main-html.html
Aug 2025
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Engineered T cells stimulate dendritic cell recruitment and antigen spreading for potent anti-tumor immunity

1
1. scibot 26 Aug 2025
  
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  DOI: 10.1016/j.xcrm.2025.102307
  
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sciencedirect.com/science/article/pii/S2666379125003805
Jul 2025
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Gasdermin C cleavage by Cathepsin S modulates Rab7 vesicles in intestinal epithelial cells to amplify anti-helminth immunity

1
1. scibot 23 Jul 2025
  
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  RRID:AB_469588
  
  DOI: 10.1016/j.immuni.2025.06.018
  
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sciencedirect.com/science/article/pii/S1074761325002870
May 2025
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Targeting WEE1 in tumor-associated dendritic cells potentiates antitumor immunity via the cGAS/STING pathway

1
1. scibot 22 May 2025
  
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  RRID:AB_469588
  
  DOI: 10.1016/j.celrep.2025.115733
  
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sciencedirect.com/science/article/pii/S2211124725005042
Mar 2025
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Radial glia integrin avb8 regulates cell autonomous microglial TGFβ1 signaling that is necessary for microglial identity

1
1. scibot 27 Mar 2025
  
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  RRID:AB_469588
  
  DOI: 10.1038/s41467-025-57684-y
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11929771/
Feb 2025
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Nanrilkefusp alfa (SOT101), an IL-15 receptor βγ superagonist, as a single agent or with anti-PD-1 in patients with advanced cancers

1
1. scibot 11 Feb 2025
  
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  RRID:AB_469588
  
  DOI: 10.1016/j.xcrm.2025.101967
  
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sciencedirect.com/science/article/pii/S2666379125000400
Jan 2025
52.53.155.43 52.53.155.43

Maternal Immunoglobulin A regulates the development of the neonatal microbiota and intestinal microbiota-specific CD4+ T cell responses

1
1. scibot 31 Jan 2025
  
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  RRID:AB_469588
  
  DOI: 10.1101/2024.06.10.598156
  
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52.53.155.43/5d9f175a1366852853c2411b63ad8211a7d72182/2024.06.10.598156v1.full-html.html
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The direct and indirect inhibition of proinflammatory adipose tissue macrophages by acarbose in diet-induced obesity

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1. scibot 03 Jan 2025
  
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  DOI: 10.1016/j.xcrm.2024.101883
  
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sciencedirect.com/science/article/pii/S2666379124006542
Oct 2024
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Damping excessive viral-induced IFN-γ rescues the impaired anti-Aspergillus host immune response in influenza-associated pulmonary aspergillosis

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1. scibot 02 Oct 2024
  
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  AB_469588
  
  DOI: 10.1016/j.ebiom.2024.105347
  
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sciencedirect.com/science/article/pii/S2352396424003839
Sep 2024
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Murine Norovirus Infection Induces TH1 Inflammatory Responses to Dietary Antigens

1
1. scibot 25 Sep 2024
  
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  RRID:AB_469587
  
  DOI: 10.1016/j.chom.2018.10.004
  
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sciencedirect.com/science/article/pii/S1931312818305420
Aug 2024
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CD4+ T cells reactive to a hybrid peptide from insulin-chromogranin A adopt a distinct effector fate and are pathogenic in autoimmune diabetes

1
1. scibot 30 Aug 2024
  
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  AB_469588
  
  DOI: 10.1016/j.immuni.2024.07.024
  
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sciencedirect.com/science/article/pii/S107476132400373X
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Soluble Tim-3 serves as a tumor prognostic marker and therapeutic target for CD8+ T cell exhaustion and anti-PD-1 resistance

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1. scibot 25 Aug 2024
  
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  DOI: 10.1016/j.xcrm.2024.101686
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11384939/
www.nature.com www.nature.com

Table 1 Reagents table

1
1. scibot 02 Aug 2024
  
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  DOI: 10.1038/s41467-019-11250-5
  
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nature.com/articles/s41467-019-11250-5/tables/1
Jul 2024
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Inhibition of SIRT1 relieves hepatocarcinogenesis via alleviating autophagy and inflammation

1
1. scibot 30 Jul 2024
  
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  AB_469588
  
  DOI: 10.1016/j.ijbiomac.2024.134120
  
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sciencedirect.com/science/article/pii/S0141813024049250
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Endomucin marks quiescent long-term multi-lineage repopulating hematopoietic stem cells and is essential for their transendothelial migration

1
1. scibot 12 Jul 2024
  
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  RRID:AB_469588
  
  DOI: 10.1016/j.celrep.2024.114475
  
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sciencedirect.com/science/article/pii/S2211124724008040
Jun 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The Aging Lacrimal Gland of Female C57BL/6J Mice Exhibits Multinucleate Macrophage Infiltration Associated With Lipid Dysregulation

1
1. scibot 09 Jun 2024
  
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  AB_469588
  
  DOI: 10.1167/iovs.65.6.1
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11156205/
May 2024
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Immunotherapy-activated T cells recruit and skewlate-stage activated M1-like macrophagesthat are critical for therapeutic efficacy

1
1. scibot 17 May 2024
  
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  RRID:AB_469588
  
  DOI: 10.1016/j.ccell.2024.04.011
  
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sciencedirect.com/science/article/pii/S1535610824001351
Mar 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Paradoxical imbalance between activated lymphocyte protein synthesis capacity and rapid division rate

1
1. scibot 23 Mar 2024
  
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  RRID:AB_469588
  
  DOI: 10.7554/eLife.89015
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10957176/
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Neutrophil-inflicted vasculature damage suppresses immune-mediated optic nerve regeneration

1
1. scibot 19 Mar 2024
  
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  DOI: 10.1016/j.celrep.2024.113931
  
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sciencedirect.com/science/article/pii/S2211124724002596
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Maternal inflammation regulates fetal emergency myelopoiesis

2
1. scibot 01 Mar 2024
  
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  RRID:AB_469588
  
  DOI: 10.1016/j.cell.2024.02.002
  
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2. scibot 01 Mar 2024
  
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  RRID:AB_469588
  
  DOI: 10.1016/j.cell.2024.02.002
  
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sciencedirect.com/science/article/pii/S0092867424001235
Feb 2024
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An iron rheostat controls hematopoietic stem cell fate

1
1. scibot 23 Feb 2024
  
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  DOI: 10.1016/j.stem.2024.01.011
  
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sciencedirect.com/science/article/pii/S1934590924000419
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IL-37d enhances COP1-mediated C/EBPβ degradation to suppress spontaneous neutrophil migration and tumor progression

1
1. scibot 22 Feb 2024
  
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  RRID:AB_469588
  
  DOI: 10.1016/j.celrep.2024.113787
  
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sciencedirect.com/science/article/pii/S2211124724001153
www.cell.com www.cell.com

The cycling and aging mouse female reproductive tract at single-cell resolution

1
1. scibot 08 Feb 2024
  
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  RRID:AB_469588
  
  DOI: 10.1016/j.cell.2024.01.021
  
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cell.com/cell/fulltext/S0092-8674(24)00058-8
Dec 2023
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Subcutaneous white adipose tissue independently regulates burn-induced hypermetabolism via immune-adipose crosstalk

1
1. scibot 22 Dec 2023
  
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  RRID:AB_469588
  
  DOI: 10.1016/j.celrep.2023.113584
  
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sciencedirect.com/science/article/pii/S2211124723015966
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The MHC-E peptide ligands for checkpoint CD94/NKG2A are governed by inflammatory signals, whereas LILRB1/2 receptors are peptide indifferent

1
1. scibot 20 Dec 2023
  
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  RRID:AB_469588
  
  DOI: 10.1016/j.celrep.2023.113516
  
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PRMT5 mediates FoxO1 methylation and subcellular localization to regulate lipophagy in myogenic progenitors

1
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Targeting neoadjuvant chemotherapy-induced metabolic reprogramming in pancreatic cancer promotes anti-tumor immunity and chemo-response

1
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  DOI: 10.1016/j.xcrm.2023.101234
  
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Radial glia promote microglial development through integrin αVβ8 -TGFβ1 signaling

1
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  DOI: 10.1101/2023.07.13.548459
  
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Jul 2023
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Aged/Autoimmune B-cell Program Defines the Early Transformation of Extranodal Lymphomas

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High-fat-diet-associated intestinal microbiota exacerbates psoriasis-like inflammation by enhancing systemic γδ T cell IL-17 production

1
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May 2023
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Towards discovering a novel family of peptides targeting neuroinflammatory states of brain microglia and astrocytes

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Inflammatory exposure drives long-lived impairment of hematopoietic stem cell self-renewal activity and accelerated aging

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Neutrophil-activating therapy for the treatment of cancer

1
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Flt3- and Tie2-Cre tracing identifies regeneration in sepsis from multipotent progenitors but not hematopoietic stem cells

1
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Bispecific PD1-IL2v and anti-PD-L1 break tumor immunity resistance by enhancing stem-like tumor-reactive CD8+ T cells and reprogramming macrophages

1
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Chimeric efferocytic receptors improve apoptotic cell clearance and alleviate inflammation

1
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Recruited monocytes/macrophages drive pulmonary neutrophilic inflammation and irreversible lung tissue remodeling in cystic fibrosis

1
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cd-22-0561-html.html

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Nov 2022
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Platelet p110β mediates platelet-leukocyte interaction and curtails bacterial dissemination in pneumococcal pneumonia

1
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The epigenetic state of IL-4-polarized macrophages enables inflammatory cistromic expansion and extended synergistic response to TLR ligands

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Cancer cell autophagy, reprogrammed macrophages, and remodeled vasculature in glioblastoma triggers tumor immunity

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Using mechanical homogenization to isolate microglia from mouse brain tissue to preserve transcriptomic integrity

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Apolipoprotein E4 impairs the response of neurodegenerative retinal microglia and prevents neuronal loss in glaucoma

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mTORC1 signaling in antigen-presenting cells of the skin restrains CD8+ T cell priming

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Jun 2022
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Tet2 deficiency drives liver microbiome dysbiosis triggering Tc1 cell autoimmune hepatitis

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Maintenance of glutamine synthetase expression alleviates endotoxin-induced sepsis via alpha-ketoglutarate-mediated demethylation

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  DOI: 10.1096/fj.202200059R
  
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Setd2 determines distinct properties of intestinal ILC3 subsets to regulate intestinal immunity

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Mucosal fungi promote gut barrier function and social behavior via Type 17 immunity

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Interferon-γ primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway

2
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Epithelial colonization by gut dendritic cells promotes their functional diversification

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Microbiota-specific T follicular helper cells drive tertiary lymphoid structures and anti-tumor immunity against colorectal cancer

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Isolation of myeloid cells from mouse brain tumors for single-cell RNA-seq analysis

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Aug 2021
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Environmental enteric dysfunction induces regulatory T cells that inhibit local CD4+ T cell responses and impair oral vaccine efficacy

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Untitled document

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  DOI: 10.1016/j.chom.2018.11.003
  
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Untitled document

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Jul 2021
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Retinoid-Sensitive Epigenetic Regulation of the Hoxb Cluster Maintains Normal Hematopoiesis and Inhibits Leukemogenesis

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Response to Fungal Dysbiosis by Gut Resident CX3CR1+ Mononuclear Phagocytes Aggravates Allergic Airway Disease

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Jun 2021
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Cytomegalovirus subverts macrophage identity

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  DOI: 10.1016/j.cell.2021.05.009
  
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GPR34-mediated sensing of lysophosphatidylserine released by apoptotic neutrophils activates type 3 innate lymphoid cells to mediate tissue repair

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  DOI: 10.1016/j.immuni.2021.05.007
  
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Chronic infection drives Dnmt3a-loss-of-function clonal hematopoiesis via IFNγ signaling

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  DOI: 10.1016/j.stem.2021.03.002
  
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White matter aging drives microglial diversity

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  DOI: 10.1016/j.neuron.2021.01.027
  
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Substance P Release by Sensory Neurons Triggers Dendritic Cell Migration and Initiates the Type-2 Immune Response to Allergens

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Patrolling Alveolar Macrophages Conceal Bacteria from the Immune System to Maintain Homeostasis

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1. scibot 24 Apr 2021
  
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  DOI: 10.1016/j.cell.2020.08.020
  
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Macrophages in SHH subgroup medulloblastoma display dynamic heterogeneity that varies with treatment modality

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  DOI: 10.1016/j.celrep.2021.108917
  
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Human gut mycobiota tune immunity via CARD9-dependent induction of anti-fungal IgG antibodies

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1. scibot 29 Mar 2021
  
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  DOI: 10.1016/j.cell.2021.01.016
  
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Disrupted Iron Metabolism and Mortality during Co-infection with Malaria and an Intestinal Gram-Negative Extracellular Pathogen

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1. scibot 22 Jan 2021
  
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Nanoparticle Vaccines Based on the Receptor Binding Domain (RBD) and Heptad Repeat (HR) of SARS-CoV-2 Elicit Robust Protective Immune Responses

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Macrophages Maintain Epithelium Integrity by Limiting Fungal Product Absorption

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Sep 2020
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Microglial A20 Protects the Brain from CD8 T-Cell-Mediated Immunopathology

1
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  DOI: 10.1016/j.celrep.2019.12.097
  
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Differential Alternative Polyadenylation Landscapes Mediate Hematopoietic Stem Cell Activation and Regulate Glutamine Metabolism

1
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  DOI: 10.1016/j.stem.2020.03.003
  
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Gata6+ Pericardial Cavity Macrophages Relocate to the Injured Heart and Prevent Cardiac Fibrosis

1
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  DOI: 10.1016/j.immuni.2019.06.010
  
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Neutrophils promote CXCR3-dependent itch in the development of atopic dermatitis

1
1. scibot 13 Jan 2020
  
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  DOI: 10.7554/eLife.48448
  
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let-7 MicroRNAs Regulate Microglial Function and Suppress Glioma Growth through Toll-Like Receptor 7

1
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  DOI: 10.1016/j.celrep.2019.11.029
  
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Age-Related Dopaminergic Innervation Augments T Helper 2-Type Allergic Inflammation in the Postnatal Lung

1
1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.immuni.2019.10.002
  
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Molecular Profiling and Functional Analysis of Macrophage-Derived Tumor Extracellular Vesicles

1
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  DOI: 10.1016/j.celrep.2019.05.008
  
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Activated CD8+ T Cells Cause Long-Term Neurological Impairment after Traumatic Brain Injury in Mice

1
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  DOI: 10.1016/j.celrep.2019.09.046
  
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Untitled document

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  DOI: 10.1016/j.chom.2019.02.007
  
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  DOI: 10.1016/j.celrep.2018.12.006
  
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sciencedirect.com/science/article/pii/S221112471831917X
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  DOI: 10.1016/j.cell.2018.12.012
  
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  DOI: 10.1016/j.stem.2018.11.023
  
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The Chemoattractant Receptor Ebi2 Drives Intranodal Naive CD4+ T Cell Peripheralization to Promote Effective Adaptive Immunity

1
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  DOI: 10.1016/j.immuni.2019.04.001
  
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Endocardially Derived Macrophages Are Essential for Valvular Remodeling

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  DOI: 10.1016/j.devcel.2019.01.021
  
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sciencedirect.com/science/article/pii/S1534580719300498
Nov 2018
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Transcriptional and Translational Differences of Microglia from Male and Female Brains

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sciencedirect.com/science/article/pii/S2211124718312427
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Daily Rhythms of TNFα Expression and Food Intake Regulate Synchrony of Plasmodium Stages with the Host Circadian Cycle

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sciencedirect.com/science/article/pii/S1931312818302178
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cell.com/cell-host-microbe/abstract/S1931-3128(18)30217-8
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Glucose Homeostasis Is Important for Immune Cell Viability during Candida Challenge and Host Survival of Systemic Fungal Infection

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sciencedirect.com/science/article/pii/S1550413118301979
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Spred1 Safeguards Hematopoietic Homeostasis against Diet-Induced Systemic Stress

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sciencedirect.com/science/article/pii/S1934590918301644
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Self-Renewal and Toll-like Receptor Signaling Sustain Exhausted Plasmacytoid Dendritic Cells during Chronic Viral Infection

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sciencedirect.com/science/article/pii/S1074761318301171

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