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Pharmacologic Modulation of ARID3A with Rimegepant Reactivates Type I Interferon Signaling and Sensitizes Triple-Negative Breast Cancer to PD-1 Blockade

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1. scibot 17 Jun 2026
  
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  DOI: 10.1002/advs.202521541
  
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advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202521541
www.nature.com www.nature.com

Intratumoral bicarbonate functions as an adjuvant to potentiate PD-1 blockade in hepatocellular carcinoma

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1. scibot 11 Jun 2026
  
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  DOI: 10.1038/s41388-026-03836-3
  
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nature.com/articles/s41388-026-03836-3
Jun 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

SETD2 Deficiency Drives Mitochondrial DNA Leakage and Creates a Druggable Dependency on BCL-xL in Clear Cell Renal Cell Carcinoma

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1. scibot 10 Jun 2026
  
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  DOI: 10.1158/0008-5472.CAN-25-3195
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13244386/
May 2026
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STING signaling in vestibular macrophages underlies Ménière’s disease pathogenesis

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1. scibot 27 May 2026
  
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  DOI: 10.1186/s12974-026-03812-4
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13200447/
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Taxane chemotherapy promotes response to TIM-3 checkpoint blockade via STING-mediated ER stress and HMGB1 secretion

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  DOI: 10.1016/j.xcrm.2026.102788
  
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sciencedirect.com/science/article/pii/S2666379126002053
Jan 2026
54.241.53.176 54.241.53.176

2026.01.07.694713v1.full-html.html

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1. scibot 15 Jan 2026
  
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  DOI: 10.64898/2026.01.07.694713
  
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54.241.53.176/f53d21943b4373e34bb96247286e23a932db89d5/2026.01.07.694713v1.full-html.html
Dec 2025
www.sciencedirect.com:5037 www.sciencedirect.com:5037

Nuclear exosome targeting complex safeguards hematopoietic stem cell self-renewal and genomic integrity through resolving R loops

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1. scibot 09 Dec 2025
  
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  DOI: 10.1016/j.celrep.2025.116650
  
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sciencedirect.com:5037/science/article/pii/S2211124725014226
Nov 2025
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Rad53 regulates RNase H1, which promotes DNA replication through sites of transcription-replication conflict

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1. scibot 18 Nov 2025
  
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  DOI: 10.1016/j.celrep.2025.116565
  
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sciencedirect.com/science/article/pii/S2211124725013373
May 2025
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TOP1 Mutations and Cross-Resistance to Antibody–Drug Conjugates in Patients with Metastatic Breast Cancer

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1. scibot 20 May 2025
  
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  DOI: 10.1158/1078-0432.CCR-24-2771
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12079096/
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SIRT2 suppresses aging-associated cGAS activation and protects aged mice from severe COVID-19

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1. scibot 17 May 2025
  
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  DOI: 10.1016/j.celrep.2025.115562
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12074670/
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Extrachromosomal DNA replication and maintenance couple with DNA damage pathway in tumors

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1. scibot 16 May 2025
  
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  DOI: 10.1016/j.cell.2025.04.012
  
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sciencedirect.com/science/article/pii/S0092867425004143
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Spatial and multiomics analysis of human and mouse lung adenocarcinoma precursors reveals TIM-3 as a putative target for precancer interception

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1. scibot 16 May 2025
  
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  DOI: 10.1016/j.ccell.2025.04.003
  
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sciencedirect.com/science/article/pii/S153561082500162X
Apr 2025
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BPS Publications

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1. scibot 04 Apr 2025
  
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  RRID:AB_470907
  
  DOI: 10.1111/bph.70040
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70040
Mar 2025
www.cell.com www.cell.com

Mitochondria sense bacterial lactate and drive release of neutrophil extracellular traps

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1. scibot 07 Mar 2025
  
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  DOI: 10.1016/j.chom.2025.02.003
  
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cell.com/cell-host-microbe/abstract/S1931-3128(25)00051-4
Feb 2025
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Compositionally unique mitochondria in filopodia support cellular migration

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1. scibot 20 Feb 2025
  
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  DOI: 10.1016/j.cub.2025.01.062
  
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sciencedirect.com/science/article/pii/S0960982225001253
Jan 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Functional conservation and divergence of arabidopsis VENOSA4 and human SAMHD1 in DNA repair

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1. scibot 25 Jan 2025
  
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  DOI: 10.1016/j.heliyon.2024.e41019
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11720913/
52.53.155.43 52.53.155.43

PDF-html.html

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1. scibot 05 Jan 2025
  
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  DOI: 10.1158/1078-0432.ccr-24-2771
  
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52.53.155.43/840490bae2d41c14c5baad0f632c2c699ffc05d9/PDF-html.html
Dec 2024
www.sciencedirect.com www.sciencedirect.com

The cGAS-STING pathway activates transcription factor TFEB to stimulate lysosome biogenesis and pathogen clearance

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1. scibot 17 Dec 2024
  
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  DOI: 10.1016/j.immuni.2024.11.017
  
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sciencedirect.com/science/article/pii/S1074761324005326
Sep 2024
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TEX264 drives selective autophagy of DNA lesions to promote DNA repair and cell survival

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1. scibot 12 Sep 2024
  
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  DOI: 10.1016/j.cell.2024.08.020
  
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sciencedirect.com/science/article/pii/S0092867424009115
Jul 2024
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Loss of ZNF408 attenuates STING-mediated immune surveillance in breast carcinogenesis

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1. scibot 24 Jul 2024
  
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  DOI: 10.1016/j.isci.2024.110276
  
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sciencedirect.com/science/article/pii/S2589004224015013
www.cell.com www.cell.com

PARP1-driven repair of topoisomerase IIIα DNA-protein crosslinks by FEN1

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1. scibot 23 Jul 2024
  
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  DOI: 10.1016/j.celrep.2024.114522
  
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cell.com/cell-reports/fulltext/S2211-1247(24)00851-9
May 2024
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TDP1 mutation causing SCAN1 neurodegenerative syndrome hampers the repair of transcriptional DNA double-strand breaks

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1. scibot 21 May 2024
  
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  DOI: 10.1016/j.celrep.2024.114214
  
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sciencedirect.com/science/article/pii/S2211124724005424
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A dynamin superfamily-like pseudoenzyme coordinates with MICOS to promote cristae architecture

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1. scibot 01 May 2024
  
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  DOI: 10.1016/j.cub.2024.04.028
  
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sciencedirect.com/science/article/pii/S0960982224004688
Jan 2024
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Multiple reorganizations of the lateral elements of the synaptonemal complex facilitate homolog segregation in Bombyx mori oocytes

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1. scibot 11 Jan 2024
  
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  DOI: 10.1016/j.cub.2023.12.018
  
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sciencedirect.com/science/article/pii/S0960982223016731
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Interferon-stimulated neutrophils as a predictor of immunotherapy response

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1. scibot 09 Jan 2024
  
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  DOI: 10.1016/j.ccell.2023.12.005
  
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sciencedirect.com/science/article/pii/S1535610823004336
Aug 2023
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Small molecule targeting of transcription-replication conflict for selective chemotherapy

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1. scibot 03 Aug 2023
  
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  DOI: 10.1016/j.chembiol.2023.07.001
  
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sciencedirect.com/science/article/pii/S2451945623002210
Jul 2023
www.cell.com www.cell.com

Human embryo live imaging reveals nuclear DNA shedding during blastocyst expansion and biopsy

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1. scibot 07 Jul 2023
  
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  DOI: 10.1016/j.cell.2023.06.003
  
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cell.com/cell/fulltext/S0092-8674(23)00643-8
Jun 2023
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Cancer cell-autonomous cGAS-STING response confers drug resistance

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1. scibot 01 Jun 2023
  
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  DOI: 10.1016/j.chembiol.2023.05.005
  
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sciencedirect.com/science/article/pii/S2451945623001411
Nov 2022
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Driving axon regeneration by orchestrating neuronal and non-neuronal innate immune responses via the IFNγ-cGAS-STING axis

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1. scibot 16 Nov 2022
  
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  DOI: 10.1016/j.neuron.2022.10.028
  
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sciencedirect.com/science/article/pii/S0896627322009618
Aug 2022
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Mitochondrial dynamics maintain muscle stem cell regenerative competence throughout adult life by regulating metabolism and mitophagy

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1. scibot 23 Aug 2022
  
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  DOI: 10.1016/j.stem.2022.07.009
  
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sciencedirect.com/science/article/pii/S1934590922003046
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DNA methyltransferase 3 alpha and TET methylcytosine dioxygenase 2 restrain mitochondrial DNA-mediated interferon signaling in macrophages

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1. scibot 06 Aug 2022
  
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  DOI: 10.1016/j.immuni.2022.06.022
  
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sciencedirect.com/science/article/pii/S1074761322002953
Jun 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

cGAS and DDX41-STING mediated intrinsic immunity spreads intercellularly to promote neuroinflammation in SOD1 ALS model

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1. scibot 17 Jun 2022
  
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  DOI: 10.1016/j.isci.2022.104404
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9194172/
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A TET1-PSPC1-Neat1 molecular axis modulates PRC2 functions in controlling stem cell bivalency

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1. scibot 09 Jun 2022
  
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  DOI: 10.1016/j.celrep.2022.110928
  
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sciencedirect.com/science/article/pii/S2211124722007100
May 2022
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DDX41 is required for cGAS-STING activation against DNA virus infection

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1. scibot 26 May 2022
  
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  DOI: 10.1016/j.celrep.2022.110856
  
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sciencedirect.com/science/article/pii/S2211124722006295
Apr 2022
www.mdpi.com www.mdpi.com

Evaluation of Ectopic Mitochondrial DNA in HeLa Cells

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1. scibot 06 Apr 2022
  
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  DOI: 10.3390/cimb44030080
  
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mdpi.com/1467-3045/44/3/80
Mar 2022
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Recruitment of DNA to tumor-derived microvesicles

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1. scibot 02 Mar 2022
  
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  DOI: 10.1016/j.celrep.2022.110443
  
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sciencedirect.com/science/article/pii/S221112472200170X
Feb 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Etoposide-induced DNA damage is increased in p53 mutants: identification of ATR and other genes that influence effects of p53 mutations on Top2-induced cytotoxicity

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1. scibot 19 Feb 2022
  
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  DOI: 10.18632/oncotarget.28195
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8845119/
Dec 2021
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The protease SPRTN and SUMOylation coordinate DNA-protein crosslink repair to prevent genome instability

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1. scibot 09 Dec 2021
  
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  DOI: 10.1016/j.celrep.2021.110080
  
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sciencedirect.com/science/article/pii/S2211124721015710
Nov 2021
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The TFAM-to-mtDNA ratio defines inner-cellular nucleoid populations with distinct activity levels

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1. scibot 24 Nov 2021
  
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  DOI: 10.1016/j.celrep.2021.110000
  
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sciencedirect.com/science/article/pii/S2211124721014790
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Z-form extracellular DNA is a structural component of the bacterial biofilm matrix

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1. scibot 04 Nov 2021
  
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  DOI: 10.1016/j.cell.2021.10.010
  
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sciencedirect.com/science/article/pii/S0092867421012204
Oct 2021
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A novel fatty acid-binding protein 5 and 7 inhibitor ameliorates oligodendrocyte injury in multiple sclerosis mouse models

1
1. scibot 06 Oct 2021
  
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  DOI: 10.1016/j.ebiom.2021.103582
  
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sciencedirect.com/science/article/pii/S2352396421003753
Aug 2021
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Evading immune surveillance via tyrosine phosphorylation of nuclear PCNA

1
1. scibot 25 Aug 2021
  
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  DOI: 10.1016/j.celrep.2021.109537
  
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sciencedirect.com/science/article/pii/S2211124721009712
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Compromised mitochondrial quality control triggers lipin1-related rhabdomyolysis

1
1. scibot 18 Aug 2021
  
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  DOI: 10.1016/j.xcrm.2021.100370
  
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sciencedirect.com/science/article/pii/S266637912100224X
Jun 2021
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Translation stress and collided ribosomes are co-activators of cGAS

1
1. scibot 10 Jun 2021
  
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  DOI: 10.1016/j.molcel.2021.05.018
  
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sciencedirect.com/science/article/pii/S1097276521004020
May 2021
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Repression of endogenous retroviruses prevents antiviral immune response and is required for mammary gland development

1
1. scibot 19 May 2021
  
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  DOI: 10.1016/j.stem.2021.04.030
  
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sciencedirect.com/science/article/pii/S193459092100206X
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Immunofluorescence microscopy-based assessment of cytosolic DNA accumulation in mammalian cells

1
1. scibot 19 May 2021
  
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  RRID:AB_470907
  
  DOI: 10.1016/j.xpro.2021.100488
  
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sciencedirect.com/science/article/pii/S2666166721001957
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Disrupting Mitochondrial Copper Distribution Inhibits Leukemic Stem Cell Self-Renewal

1
1. scibot 09 May 2021
  
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  DOI: 10.1016/j.stem.2020.04.010
  
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sciencedirect.com/science/article/pii/S1934590920301491
Apr 2021
journals.plos.org journals.plos.org

ELISA detection of MPO-DNA complexes in human plasma is error-prone and yields limited information on neutrophil extracellular traps formed in vivo

1
1. scibot 27 Apr 2021
  
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  DOI: 10.1371/journal.pone.0250265
  
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journals.plos.org/plosone/article
Feb 2021
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FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells

1
1. scibot 27 Feb 2021
  
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  RRID:AB_470907
  
  DOI: 10.1016/j.cell.2020.11.042
  
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sciencedirect.com/science/article/pii/S0092867420316147
elifesciences.org elifesciences.org

Stable transplantation of human mitochondrial DNA by high-throughput, pressurized isolated mitochondrial delivery

1
1. scibot 11 Feb 2021
  
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  RRID:AB_470907
  
  DOI: 10.7554/eLife.63102
  
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elifesciences.org/articles/63102
Jan 2021
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DNA and RNA Cleavage Complexes and Repair Pathway for TOP3B RNA- and DNA-Protein Crosslinks

1
1. scibot 05 Jan 2021
  
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  RRID:AB_470907
  
  DOI: 10.1016/j.celrep.2020.108569
  
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sciencedirect.com/science/article/pii/S2211124720315588
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Pressure-Driven Mitochondrial Transfer Pipeline Generates Mammalian Cells of Desired Genetic Combinations and Fates

1
1. scibot 05 Jan 2021
  
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  DOI: 10.1016/j.celrep.2020.108562
  
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sciencedirect.com/science/article/pii/S2211124720315515
Dec 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Cross-reactivity to Kynureninase Tolerizes B Cells that Express the HIV-1 Broadly Neutralizing Antibody 2F5

1
1. scibot 16 Dec 2020
  
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  RRID:AB_470907
  
  DOI: 10.4049/jimmunol.1900069
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6904439/
Sep 2020
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The ARK Assay Is a Sensitive and Versatile Method for the Global Detection of DNA-Protein Crosslinks

1
1. scibot 26 Sep 2020
  
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  RRID:AB_470907
  
  DOI: 10.1016/j.celrep.2019.12.067
  
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sciencedirect.com/science/article/pii/S2211124719317243
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Sen1 Is Recruited to Replication Forks via Ctf4 and Mrc1 and Promotes Genome Stability

1
1. scibot 05 Sep 2020
  
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  DOI: 10.1016/j.celrep.2020.01.087
  
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sciencedirect.com/science/article/pii/S2211124720301212
Jan 2020
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Epigenetic Compensation Promotes Liver Regeneration

1
1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.devcel.2019.05.034
  
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sciencedirect.com/science/article/pii/S1534580719304472
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RNase H1 and H2 Are Differentially Regulated to Process RNA-DNA Hybrids

1
1. scibot 13 Jan 2020
  
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  RRID:AB_470907
  
  DOI: 10.1016/j.celrep.2019.10.108
  
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sciencedirect.com/science/article/pii/S221112471931441X
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

GCNA Preserves Genome Integrity and Fertility Across Species

1
1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.devcel.2019.11.007
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6946843/
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Upregulation of the Autophagy Adaptor p62/SQSTM1 Prolongs Health and Lifespan in Middle-Aged Drosophila

1
1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.celrep.2019.06.070
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6688777/
www.cell.com www.cell.com

Mitochondrial Damage Causes Inflammation via cGAS-STING Signaling in Acute Kidney Injury

1
1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.celrep.2019.09.050
  
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cell.com/cell-reports/fulltext/S2211-1247(19)31238-0
Nov 2017
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MOF Acetyl Transferase Regulates Transcription and Respiration in Mitochondria

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1. scibot 08 Nov 2017
  
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Monoclonal antibodies against DNA-binding tips of DNABII proteins disrupt biofilms in vitro and induce bacterial clearance in vivo

1
1. scibot 08 Nov 2017
  
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sciencedirect.com/science/article/pii/S235239641630278X

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