335 Matching Annotations
  1. Last 7 days
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    Bisbiguanide analogs induce mitochondrial stress to inhibit lung cancer cell invasion
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    ncbi.nlm.nih.gov/pmc/articles/PMC11022046/
  3. Apr 2024
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    “Heterogeneous subpopulations of GABAAR-responding neurons coexist across neuronal networks scales and developmental stages in health and disease”
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    ncbi.nlm.nih.gov/pmc/articles/PMC10966311/
  5. Mar 2024
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    Histone lysine demethylase 4 family proteins maintain the transcriptional program and adrenergic cellular state of MYCN-amplified neuroblastoma
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    sciencedirect.com/science/article/pii/S2666379124001149
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    SIRT4 loss reprograms intestinal nucleotide metabolism to support proliferation following perturbation of homeostasis
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    sciencedirect.com/science/article/pii/S2211124724003036
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    HDAC5 enhances IRF3 activation and is targeted for degradation by protein C6 from orthopoxviruses including Monkeypox virus and Variola virus
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    sciencedirect.com/science/article/pii/S2211124724001165
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    The dispensability of 14-3-3 proteins for the regulation of human cardiac sodium channel Nav1.5
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    ncbi.nlm.nih.gov/pmc/articles/PMC10919853/
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    Targeting up-regulated cIAP2 in SOX10-deficient drug tolerant melanoma
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  11. Feb 2024
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    The IRAK1/IRF5 axis initiates IL-12 response by dendritic cells and control of Toxoplasma gondii infection
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    sciencedirect.com/science/article/pii/S2211124724001232
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    Dopamine-iron homeostasis interaction rescues mitochondrial fitness in Parkinson’s disease
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    Lifespan Effects of Muscle-Specific Androgen Receptor Overexpression on Body Composition of Male and Female Rats
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    GLUT1-mediated glucose import in B cells is critical for anaplerotic balance and humoral immunity
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    Acetylation-induced proteasomal degradation of the activated glucocorticoid receptor limits hormonal signaling
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    Cooperation between PRMT1 and PRMT6 drives lung cancer health disparities among Black/African American men
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    Neuronal cell-based high-throughput screen for enhancers of mitochondrial function reveals luteolin as a modulator of mitochondria-endoplasmic reticulum coupling
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  19. Jan 2024
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    Unique transcriptional profiles underlie osteosarcomagenesis driven by different p53 mutants
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    Astrocytic TDP-43 dysregulation impairs memory by modulating antiviral pathways and interferon-inducible chemokines
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    Distinct modes of telomere synthesis and extension contribute to Alternative Lengthening of Telomeres
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    ncbi.nlm.nih.gov/pmc/articles/PMC10783591/
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    A mitophagy sensor PPTC7 controls BNIP3 and NIX degradation to regulate mitochondrial mass
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    sciencedirect.com/science/article/pii/S1097276523010146
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    Genetic insights into carbohydrate sulfotransferase 8 and its impact on the immunotherapy efficacy of cancer
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    sciencedirect.com/science/article/pii/S2211124723016522
  25. Dec 2023
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    A mitophagy sensor PPTC7 controls BNIP3 and NIX degradation to regulate mitochondrial mass
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  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Topoisomerase 1 Inhibition in MYC-Driven Cancer Promotes Aberrant R-Loop Accumulation to Induce Synthetic Lethality
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    Irreversible inhibition of TRF2TRFH recruiting functions by a covalent cyclic peptide induces telomeric replication stress in cancer cells
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    MORG1 limits mTORC1 signaling by inhibiting Rag GTPases
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  30. Nov 2023
  31. www.cell.com www.cell.com
    Oncogenic signals prime cancer cells for toxic cell overgrowth during a G1 cell cycle arrest
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    cell.com/molecular-cell/fulltext/S1097-2765(23)00857-2
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    O-GlcNAcylation regulates OTX2's proteostasis.
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  33. Oct 2023
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    JNK mediates cell death by promoting the ubiquitination of the apurinic/apyrimidinic endonuclease APE1
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    Identification of hyperoxidized PRDX3 as a ferroptosis marker reveals ferroptotic damage in chronic liver diseases
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    Human APOBEC3B promotes tumor development in vivo including signature mutations and metastases
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  37. Sep 2023
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    LAT1 (SLC7A5) catalyzes Copper(histidinate) transport switching from antiport to uniport mechanism.
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  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dynamic association of the intramembrane proteases SPPL2a/b and their substrates with tetraspanin-enriched microdomains
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  40. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Alterations of lipid-mediated mitophagy result in aging-dependent sensorimotor defects
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    Ectopic expression of DOCK8 regulates lysosome-mediated pancreatic tumor cell invasion
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  42. Aug 2023
  43. 52.53.155.43 52.53.155.43
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  44. Jul 2023
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    The kinesin Kif21b binds myosin Va and mediates changes in actin dynamics underlying homeostatic synaptic downscaling
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  46. 52.53.155.43 52.53.155.43
    Alcohol Clin Exp Res - 2023 - Shanmugam - Ethanol inhibition of undifferentiated rat neural progenitor cell replication-html.html
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  47. Jun 2023
  48. 52.53.155.43 52.53.155.43
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    Lysosomal LAMP proteins regulate lysosomal pH by direct inhibition of the TMEM175 channel
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    Sublethal necroptosis signaling promotes inflammation and liver cancer
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    Temporary serine protease inhibition and the role of SPINK2 in human bone marrow
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  53. May 2023
  54. www.sciencedirect.com www.sciencedirect.com
    An isoform of the giant protein titin is a master regulator of human T lymphocyte trafficking
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    Differential cell-cycle control by oscillatory versus sustained Hes1 expression via p21
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    Mitochondrial Bcl-xL promotes brain synaptogenesis by controlling non-lethal caspase activation
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    Protein quality control machinery supports primary ciliogenesis by eliminating GDP-bound Rab8-family GTPases
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    Vitamin B5 and succinyl-CoA improve ineffective erythropoiesis in SF3B1 mutated myelodysplasia
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    Compounds activating VCP D1 ATPase enhance both autophagic and proteasomal neurotoxic protein clearance
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    BAP1 loss is associated with higher ASS1 expression in epithelioid mesothelioma: implications for therapeutic stratification.
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    Nonlytic Quasi-Enveloped Hepatovirus Release Is Facilitated by pX Protein Interaction with the E3 Ubiquitin Ligase ITCH
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    Inter-organ insulin-leptin signal crosstalk from the liver enhances survival during food shortages
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    Salmonella invasion of a cell is self-limiting due to effector-driven activation of N-WASP
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    Microglial-to-neuronal CCR5 signaling regulates autophagy in neurodegeneration
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    Astrocytic TDP-43 dysregulation impairs memory by modulating antiviral pathways and interferon-inducible chemokines
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    NAD depletion mediates cytotoxicity in human neurons with autophagy deficiency
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    Tumor suppressive role of the musculoaponeurotic fibrosarcoma gene in colorectal cancer
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    Polymerase iota (Pol ι) prevents PrimPol-mediated nascent DNA synthesis and chromosome instability
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    Polymerase iota (Pol ι) prevents PrimPol-mediated nascent DNA synthesis and chromosome instability
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    Human APOBEC3B promotes tumor heterogeneity in vivo including signature mutations and metastases
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    The ancestral ESCRT protein TOM1L2 selects ubiquitinated cargoes for retrieval from cilia
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    Renal CD81 interacts with sodium potassium 2 chloride cotransporter and sodium chloride cotransporter in rats with lipopolysaccharide-induced preeclampsia
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    Topological regulation of a transmembrane protein by luminal-to-cytosolic retrotranslocation of glycosylated sequence
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    mRNAs encoding IL-12 and a decoy-resistant variant of IL-18 synergize to engineer T cells for efficacious intratumoral adoptive immunotherapy
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    Pyruvate dehydrogenase fuels a critical citrate pool that is essential for Th17 cell effector functions
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    Restoration of Adult Neurogenesis by Intranasal Administration of Gangliosides GD3 and GM1 in The Olfactory Bulb of A53T Alpha-Synuclein-Expressing Parkinson’s-Disease Model Mice
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    Chemical inhibition of mitochondrial fission via targeting the DRP1-receptor interaction
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    DDX47, MeCP2, and other functionally heterogeneous factors protect cells from harmful R loops
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    Downregulation of iNOS/NO Promotes Epithelial–Mesenchymal Transition and Metastasis in Colorectal Cancer
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    Glutamine synthetase expression rescues human dendritic cell survival in a glutamine-deprived environment
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    GOT1 regulates CD8+ effector and memory T cell generation
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    Artificial extracellular matrix scaffolds of mobile molecules enhance maturation of human stem cell-derived neurons
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    The US9-Derived Protein gPTB9TM Modulates APP Processing Without Targeting Secretase Activities
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    The hepatic integrated stress response suppresses the somatotroph axis to control liver damage in nonalcoholic fatty liver disease
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    Regulation of RNA localization during oocyte maturation by dynamic RNA-ER association and remodeling of the ER
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    Mitochondrial cristae architecture protects against mtDNA release and inflammation
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    Raptinal induces Gasdermin E-dependent pyroptosis in naive and therapy-resistant melanoma
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  94. Nov 2022
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    CROCCP2 acts as a human-specific modifier of cilia dynamics and mTOR signaling to promote expansion of cortical progenitors
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    Nonlytic Quasi-Enveloped Hepatovirus Release Is Facilitated by pX Protein Interaction with the E3 Ubiquitin Ligase ITCH
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  97. Oct 2022
  98. 52.53.155.43 52.53.155.43
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  99. www.nature.com www.nature.com
    The autophagy inducer SMER28 attenuates microtubule dynamics mediating neuroprotection
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  100. www.sciencedirect.com www.sciencedirect.com
    Non-canonical inflammasome activation analysis in a mouse model of Citrobacter rodentium infection
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  101. Sep 2022
  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multi-omics profiling shows BAP1 loss is associated with upregulated cell adhesion molecules in uveal melanoma
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  103. academic.oup.com academic.oup.com
    Effects of Wnt-β-catenin signaling and sclerostin on the phenotypes of rat pheochromocytoma PC12 cells
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  104. Aug 2022
  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    AR-V7 exhibits non-canonical mechanisms of nuclear import and chromatin engagement in castrate-resistant prostate cancer
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    The IRAK4 scaffold integrates TLR4-driven TRIF and MYD88 signaling pathways
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  107. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Paclitaxel in vitro reversibly sensitizes the excitability of IB4(−) and IB4(+) sensory neurons from male and female rats
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  108. Jul 2022
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    The immune checkpoint ICOSLG is a relapse-predicting biomarker and therapeutic target in infant t(4;11) acute lymphoblastic leukemia
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  110. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Slitrk2 deficiency causes hyperactivity with altered vestibular function and serotonergic dysregulation
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  111. Jun 2022
  112. 52.53.155.43 52.53.155.43
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    A function for Ataxia telangiectasia and Rad3-related (ATR) kinase in cytokinetic abscission
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    Counteracting chromatin effects of a splicing-correcting antisense oligonucleotide improves its therapeutic efficacy in spinal muscular atrophy
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    Downregulation of surface AMPA receptor expression in the striatum following prolonged social isolation, a role of mGlu5 receptors
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  116. May 2022
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    Activation of cannabinoid receptors in breast cancer cells improves osteoblast viability in cancer-bone interaction model while reducing breast cancer cell survival and migration
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    Plasmodium parasitophorous vacuole membrane-resident protein UIS4 manipulates host cell actin to avoid parasite elimination
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    Mesothelial cell-derived antigen-presenting cancer-associated fibroblasts induce expansion of regulatory T cells in pancreatic cancer
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  120. Apr 2022
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    The TORC1 phosphoproteome in C. elegans reveals roles in transcription and autophagy
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    HIV-1 Vpr drives a tissue residency-like phenotype during selective infection of resting memory T cells
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    Interrogation of cancer gene dependencies reveals paralog interactions of autosome and sex chromosome-encoded genes
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    Protrudin regulates FAK activation, endothelial cell migration and angiogenesis
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    Microbiota-dependent activation of the myeloid calcineurin-NFAT pathway inhibits B7H3- and B7H4-dependent anti-tumor immunity in colorectal cancer
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  126. Mar 2022
  127. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Macrophage network dynamics depend on haptokinesis for optimal local surveillance
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  128. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FBXO47 is essential for preventing the synaptonemal complex from premature disassembly in mouse male meiosis
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    Contribution of cyclooxygenase-1-dependent prostacyclin synthesis to bradykinin-induced dermal extravasation
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    Diacylglycerol kinase η regulates cell proliferation and its levels are elevated by glucocorticoids in undifferentiated neuroblastoma cells
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  131. Feb 2022
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    Poxviruses and paramyxoviruses use a conserved mechanism of STAT1 antagonism to inhibit interferon signaling
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      DOI: 10.1016/j.chom.2022.01.014

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  133. Dec 2021
  134. academic.oup.com academic.oup.com
    Hypothalamic miR-1983 targets insulin receptor beta and the insulin-mediated miR-1983 increase is blocked by metformin
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    SOX10 requirement for melanoma tumor growth is due, in part, to immune-mediated effects
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  136. Nov 2021
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    Lemur tail kinase 1 (LMTK1) regulates the endosomal localization of β-secretase BACE1
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  138. Oct 2021
  139. elifesciences.org elifesciences.org
    HIF1α stabilization in hypoxia is not oxidant-initiated
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  140. Sep 2021
  141. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Neuroimmunological complications arising from chemotherapy-induced gut toxicity and opioid exposure in female dark agouti rats
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    Homeostatic control of nuclear-encoded mitochondrial gene expression by the histone variant H2A.Z is essential for neuronal survival
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    The prolyl-isomerase PIN1 is essential for nuclear Lamin-B structure and function and protects heterochromatin under mechanical stress
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    FADS2-dependent fatty acid desaturation dictates cellular sensitivity to ferroptosis and permissiveness for hepatitis C virus replication
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    Viral targeting of glioblastoma stem cells with patient-specific genetic and post-translational p53 deregulations
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  146. Aug 2021
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    Skin exposure to UVB light induces a skin-brain-gonad axis and sexual behavior
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  148. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of response signatures for tankyrase inhibitor treatment in tumor cell lines
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  193. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  194. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Suppression of β-catenin signaling in colon carcinoma cells by a bacterial protein
    1
    1. scibot 20 May 2021
      rabbit polyclonal anti-actin

      DOI: 10.1002/ijc.33562

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  195. onlinelibrary.wiley.com onlinelibrary.wiley.com
    AMPK‐regulated miRNA‐210‐3p is activated during ischaemic neuronal injury and modulates PI3K‐p70S6K signalling
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      DOI: 10.1111/jnc.15347

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  196. www.sciencedirect.com www.sciencedirect.com
    NLR-1/CASPR Anchors F-Actin to Promote Gap Junction Formation
    1
    1. scibot 05 May 2021
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      DOI: 10.1016/j.devcel.2020.10.020

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  197. www.sciencedirect.com www.sciencedirect.com
    Aging-dependent mitochondrial dysfunction mediated by ceramide signaling inhibits antitumor T cell response
    1
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      DOI: 10.1016/j.celrep.2021.109076

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    sciencedirect.com/science/article/pii/S2211124721004071
  198. Apr 2021
  199. www.sciencedirect.com www.sciencedirect.com
    PHD3 Loss Promotes Exercise Capacity and Fat Oxidation in Skeletal Muscle
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      DOI: 10.1016/j.cmet.2020.06.017

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  200. www.sciencedirect.com www.sciencedirect.com
    Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity
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      DOI: 10.1016/j.cell.2020.11.009

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  201. www.sciencedirect.com www.sciencedirect.com
    A Genetic Map of the Response to DNA Damage in Human Cells
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      Rabbit monoclonal anti-β-actin

      DOI: 10.1016/j.cell.2020.05.040

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  202. www.sciencedirect.com www.sciencedirect.com
    MDMX acts as a pervasive preleukemic-to-acute myeloid leukemia transition mechanism
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      DOI: 10.1016/j.ccell.2021.02.006

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  203. www.sciencedirect.com www.sciencedirect.com
    Targeting RSPO3-LGR4 Signaling for Leukemia Stem Cell Eradication in Acute Myeloid Leukemia
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      DOI: 10.1016/j.ccell.2020.05.014

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  204. Mar 2021
  205. ueaeprints.uea.ac.uk ueaeprints.uea.ac.uk
    Pharmacological and genetic characterisation of the canine P2X4 receptor
    1
    1. scibot 29 Mar 2021
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      DOI: 10.1111/bph.15009This

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  206. link.springer.com link.springer.com
    Neuronal cell-based high-throughput screen for enhancers of mitochondrial function reveals luteolin as a modulator of mitochondria-endoplasmic reticulum coupling
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    1. scibot 27 Mar 2021
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      DOI: 10.1186/s12915-021-00979-5

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  207. molecularautism.biomedcentral.com molecularautism.biomedcentral.com
    Hippocampal neurons isolated from rats subjected to the valproic acid model mimic in vivo synaptic pattern: evidence of neuronal priming during early development in autism spectrum disorders
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      DOI: 10.1186/s13229-021-00428-8

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  208. www.cell.com www.cell.com
    BLM has Contrary Effects on Repeat-Mediated Deletions, based on the Distance of DNA DSBs to a Repeat and Repeat Divergence
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    1. scibot 03 Mar 2021
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      DOI: 10.1016/j.celrep.2020.01.001

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  209. Feb 2021
  210. www.nature.com www.nature.com
    VCP/p97 regulates Beclin-1-dependent autophagy initiation
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    1. scibot 28 Feb 2021
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      DOI: 10.1038/s41589-020-00726-x

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  211. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Myelination defects in the medial prefrontal cortex of Fkbp5 knockout mice
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      DOI: 10.1096/fj.202001883R

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  212. www.cell.com www.cell.com
    Dynamic Assembly and Disassembly of the Human DNA Polymerase δ Holoenzyme on the Genome In Vivo
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    1. scibot 24 Feb 2021
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      DOI: 10.1016/j.celrep.2019.12.101

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  213. elifesciences.org elifesciences.org
    Seizures are a druggable mechanistic link between TBI and subsequent tauopathy
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      DOI: 10.7554/eLife.58744

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  214. Jan 2021
  215. www.sciencedirect.com www.sciencedirect.com
    Zinc Finger Protein SALL4 Functions through an AT-Rich Motif to Regulate Gene Expression
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      DOI: 10.1016/j.celrep.2020.108574

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  216. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A distinctive distribution of hypoxia‐inducible factor‐1α in cultured renal tubular cells with hypoperfusion simulated by coverslip placement
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    1. scibot 05 Jan 2021
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      DOI: 10.14814/phy2.14689

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  217. Dec 2020
  218. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Identification of truncated C‐terminal fragments of the Alzheimer’s disease amyloid protein precursor derived from sequential proteolytic pathways
    1
    1. scibot 07 Dec 2020
      β‐actin

      DOI: 10.1111/jnc.15143

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  219. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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      DOI: 10.1111/bph.15060

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  220. www.mdpi.com www.mdpi.com
    Comparative Proteomics Unveils LRRFIP1 as a New Player in the DAPK1 Interactome of Neurons Exposed to Oxygen and Glucose Deprivation
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      RRID:AB_476693

      DOI: 10.3390/antiox9121202

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  221. Nov 2020
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    TRF2 Mediates Replication Initiation within Human Telomeres to Prevent Telomere Dysfunction
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      DOI: 10.1016/j.celrep.2020.108379

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  223. Oct 2020
  224. www.nature.com www.nature.com
    Re-establishment of the epigenetic state and rescue of kinome deregulation in Ts65Dn mice upon treatment with green tea extract and environmental enrichment
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      DOI: 10.1038/s41598-020-72625-z

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    Rescuing Over-activated Microglia Restores Cognitive Performance in Juvenile Animals of the Dp(16) Mouse Model of Down Syndrome
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      DOI: 10.1016/j.neuron.2020.09.010

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    The mTORC1/S6K/PDCD4/eIF4A Axis Determines Outcome of Mitotic Arrest
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      DOI: 10.1016/j.celrep.2020.108230

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  227. Sep 2020
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    Linkage of Non-receptor Tyrosine Kinase Fyn to mGlu5 Receptors in Striatal Neurons in a Depression Model
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      DOI: 10.1016/j.neuroscience.2020.02.048

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  229. www.nature.com www.nature.com
    Urinary ERdj3 and mesencephalic astrocyte-derived neutrophic factor identify endoplasmic reticulum stress in glomerular disease
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      DOI: 10.1038/s41374-020-0416-5

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    The Set7 Lysine Methyltransferase Regulates Plasticity in Oxidative Phosphorylation Necessary for Trained Immunity Induced by β-Glucan
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      DOI: 10.1016/j.celrep.2020.107548

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  231. cancerres.aacrjournals.org cancerres.aacrjournals.org
    Suppression of ABCE1-mediated mRNA translation limits N-MYC-driven cancer progression
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      DOI: 10.1158/0008-5472.CAN-19-3914

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  232. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Parkin contributes to synaptic vesicle autophagy in Bassoon-deficient mice
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      DOI: 10.7554/eLife.56590

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  233. elifesciences.org elifesciences.org
    A virus-packageable CRISPR screen identifies host factors mediating interferon inhibition of HIV
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      DOI: 10.7554/eLife.39823

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  234. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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      DOI: 10.1111/bph.15009

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