372 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SIKs regulate HDAC7 stabilization and cytokine recall in late-stage T cell effector differentiation
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  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mutations that prevent phosphorylation of the BMP4 prodomain impair proteolytic maturation of homodimers leading to early lethality in mice
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  4. Dec 2024
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    Characterization of a novel variant in the NR3C1 gene: differentiating glucocorticoid resistance from Cushing Syndrome
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  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Transcriptional and functional regulation of cell cycle and UV response by PPARβ in human skin epidermal cells
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  7. Nov 2024
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    Heterogeneous Effects of Src Inhibition on Determinants of Metastasis in Preclinical Models of Human Bladder Cancer
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    TMEM39A and TMEM131 facilitate bulk transport of ECM proteins through large COPII vesicle formation
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    sciencedirect.com/science/article/pii/S167385272400287X
  10. Sep 2024
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    Ultrasonic Neuromodulation via Astrocytic TRPA1
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    Protein UFMylation regulates early events during ribosomal DNA-damage response
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    Synaptic rearrangement of NMDA receptors controls memory engram formation and malleability in the cortex
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  14. Aug 2024
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    Non-canonical function of ADAM10 in presynaptic plasticity
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    The FXR1 network acts as a signaling scaffold for actomyosin remodeling
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    In vivo vulnerabilities to GPX4 and HDAC inhibitors in drug-persistent versus drug-resistant BRAFV600E lung adenocarcinoma
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    Steroid hormones and human choriogonadotropin influence the distribution of alpha6-integrin and desmoplakin 1 in gland-like endometrial epithelial spheroids
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    Modelling TFE renal cell carcinoma in mice reveals a critical role of WNT signaling
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    Regulation of synaptic MAPK/ERK phosphorylation in the rat striatum and medial prefrontal cortex by dopamine and muscarinic acetylcholine receptors
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  21. Jul 2024
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    Alterations of ceramide synthesis induce PD-L1 internalization and signaling to regulate tumor metastasis and immunotherapy response
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    Netrin signaling mediates survival of dormant epithelial ovarian cancer cells
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    Leveraging a self-cleaving peptide for tailored control in proximity labeling proteomics
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    YY1-mediated enhancer-promoter communication in the immunoglobulin μ locus is regulated by MSL/MOF recruitment
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    Tumour-specific activation of a tumour-blood transport improves the diagnostic accuracy of blood tumour markers in mice
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    A Th17 cell-intrinsic glutathione/mitochondrial-IL-22 axis protects against intestinal inflammation
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  28. www.mdpi.com www.mdpi.com
    HER4 Affects Sensitivity to Tamoxifen and Abemaciclib in Luminal Breast Cancer Cells and Restricts Tumor Growth in MCF-7-Based Humanized Tumor Mice
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  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Insulin Potentiates JAK/STAT Signaling to Broadly Inhibit Flavivirus Replication in Insect Vectors
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  30. Jun 2024
  31. www.mdpi.com www.mdpi.com
    Submandibular Gland Pathogenesis Following SARS-CoV-2 Infection and Implications for Xerostomia
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  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumour microenvironment programming by an RNA–RNA-binding protein complex creates a druggable vulnerability in IDH-wild-type glioblastoma
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  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IRX4204 Induces Senescence and Cell Death in HER2-positive Breast Cancer and Synergizes with Anti-HER2 Therapy
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  34. May 2024
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    Lysophosphatidic Acid Stimulates Mitogenic Activity and Signaling in Human Neuroblastoma Cells through a Crosstalk with Anaplastic Lymphoma Kinase
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  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Opportunistic pathogen Porphyromonas gingivalis targets the LC3B-ceramide complex and mediates lethal mitophagy resistance in oral tumors
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  37. 52.53.155.43 52.53.155.43
    mcr-23-0295-html.html
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    Therapeutic avenues in bone repair: Harnessing an anabolic osteopeptide, PEPITEM, to boost bone growth and prevent bone loss
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  39. www.biorxiv.org www.biorxiv.org
    Viral mimicry and memory deficits upon microglial deletion of ATRX
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  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neoadjuvant radiotherapy in ER+, HER2+, and triple-negative -specific breast cancer based humanized tumor mice enhances anti-PD-L1 treatment efficacy
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  41. www.science.org www.science.org
    p37 regulates VCP/p97 shuttling and functions in the nucleus and cytosol
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      DOI: 10.1126/sciadv.adl6082

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  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    p37 regulates VCP/p97 shuttling and functions in the nucleus and cytosol
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  43. Apr 2024
  44. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Candesartan upregulates angiotensin-converting enzyme 2 in kidneys of male animals by decreased ubiquitination
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  45. www.sciencedirect.com www.sciencedirect.com
    Dopamine‑iron homeostasis interaction rescues mitochondrial fitness in Parkinson's disease
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  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bisbiguanide analogs induce mitochondrial stress to inhibit lung cancer cell invasion
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  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    “Heterogeneous subpopulations of GABAAR-responding neurons coexist across neuronal networks scales and developmental stages in health and disease”
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  48. Mar 2024
  49. www.sciencedirect.com www.sciencedirect.com
    Histone lysine demethylase 4 family proteins maintain the transcriptional program and adrenergic cellular state of MYCN-amplified neuroblastoma
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    SIRT4 loss reprograms intestinal nucleotide metabolism to support proliferation following perturbation of homeostasis
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    HDAC5 enhances IRF3 activation and is targeted for degradation by protein C6 from orthopoxviruses including Monkeypox virus and Variola virus
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    The dispensability of 14-3-3 proteins for the regulation of human cardiac sodium channel Nav1.5
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    Targeting up-regulated cIAP2 in SOX10-deficient drug tolerant melanoma
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  54. Feb 2024
  55. www.sciencedirect.com www.sciencedirect.com
    The IRAK1/IRF5 axis initiates IL-12 response by dendritic cells and control of Toxoplasma gondii infection
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    Dopamine-iron homeostasis interaction rescues mitochondrial fitness in Parkinson’s disease
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    Lifespan Effects of Muscle-Specific Androgen Receptor Overexpression on Body Composition of Male and Female Rats
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    GLUT1-mediated glucose import in B cells is critical for anaplerotic balance and humoral immunity
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    Acetylation-induced proteasomal degradation of the activated glucocorticoid receptor limits hormonal signaling
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    Cooperation between PRMT1 and PRMT6 drives lung cancer health disparities among Black/African American men
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    Neuronal cell-based high-throughput screen for enhancers of mitochondrial function reveals luteolin as a modulator of mitochondria-endoplasmic reticulum coupling
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  62. Jan 2024
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Unique transcriptional profiles underlie osteosarcomagenesis driven by different p53 mutants
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    Astrocytic TDP-43 dysregulation impairs memory by modulating antiviral pathways and interferon-inducible chemokines
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    Distinct modes of telomere synthesis and extension contribute to Alternative Lengthening of Telomeres
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    A mitophagy sensor PPTC7 controls BNIP3 and NIX degradation to regulate mitochondrial mass
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    Genetic insights into carbohydrate sulfotransferase 8 and its impact on the immunotherapy efficacy of cancer
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    A mitophagy sensor PPTC7 controls BNIP3 and NIX degradation to regulate mitochondrial mass
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    Topoisomerase 1 Inhibition in MYC-Driven Cancer Promotes Aberrant R-Loop Accumulation to Induce Synthetic Lethality
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    Irreversible inhibition of TRF2TRFH recruiting functions by a covalent cyclic peptide induces telomeric replication stress in cancer cells
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    MORG1 limits mTORC1 signaling by inhibiting Rag GTPases
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    Oncogenic signals prime cancer cells for toxic cell overgrowth during a G1 cell cycle arrest
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    O-GlcNAcylation regulates OTX2's proteostasis.
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  76. Oct 2023
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    JNK mediates cell death by promoting the ubiquitination of the apurinic/apyrimidinic endonuclease APE1
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    Identification of hyperoxidized PRDX3 as a ferroptosis marker reveals ferroptotic damage in chronic liver diseases
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    Human APOBEC3B promotes tumor development in vivo including signature mutations and metastases
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    LAT1 (SLC7A5) catalyzes Copper(histidinate) transport switching from antiport to uniport mechanism.
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    Dynamic association of the intramembrane proteases SPPL2a/b and their substrates with tetraspanin-enriched microdomains
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    Alterations of lipid-mediated mitophagy result in aging-dependent sensorimotor defects
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    Ectopic expression of DOCK8 regulates lysosome-mediated pancreatic tumor cell invasion
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  87. Jul 2023
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    The kinesin Kif21b binds myosin Va and mediates changes in actin dynamics underlying homeostatic synaptic downscaling
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    Alcohol Clin Exp Res - 2023 - Shanmugam - Ethanol inhibition of undifferentiated rat neural progenitor cell replication-html.html
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  90. Jun 2023
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    Lysosomal LAMP proteins regulate lysosomal pH by direct inhibition of the TMEM175 channel
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    Sublethal necroptosis signaling promotes inflammation and liver cancer
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    Temporary serine protease inhibition and the role of SPINK2 in human bone marrow
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  96. May 2023
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    An isoform of the giant protein titin is a master regulator of human T lymphocyte trafficking
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    Differential cell-cycle control by oscillatory versus sustained Hes1 expression via p21
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    Mitochondrial Bcl-xL promotes brain synaptogenesis by controlling non-lethal caspase activation
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    Protein quality control machinery supports primary ciliogenesis by eliminating GDP-bound Rab8-family GTPases
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    Vitamin B5 and succinyl-CoA improve ineffective erythropoiesis in SF3B1 mutated myelodysplasia
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    Compounds activating VCP D1 ATPase enhance both autophagic and proteasomal neurotoxic protein clearance
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    BAP1 loss is associated with higher ASS1 expression in epithelioid mesothelioma: implications for therapeutic stratification.
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  104. Apr 2023
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    Nonlytic Quasi-Enveloped Hepatovirus Release Is Facilitated by pX Protein Interaction with the E3 Ubiquitin Ligase ITCH
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    Inter-organ insulin-leptin signal crosstalk from the liver enhances survival during food shortages
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    Salmonella invasion of a cell is self-limiting due to effector-driven activation of N-WASP
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    Microglial-to-neuronal CCR5 signaling regulates autophagy in neurodegeneration
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    Astrocytic TDP-43 dysregulation impairs memory by modulating antiviral pathways and interferon-inducible chemokines
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    NAD depletion mediates cytotoxicity in human neurons with autophagy deficiency
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    Tumor suppressive role of the musculoaponeurotic fibrosarcoma gene in colorectal cancer
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    Polymerase iota (Pol ι) prevents PrimPol-mediated nascent DNA synthesis and chromosome instability
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    Polymerase iota (Pol ι) prevents PrimPol-mediated nascent DNA synthesis and chromosome instability
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    Human APOBEC3B promotes tumor heterogeneity in vivo including signature mutations and metastases
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    The ancestral ESCRT protein TOM1L2 selects ubiquitinated cargoes for retrieval from cilia
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    SARS-CoV-2 viral protein Nsp2 stimulates translation under normal and hypoxic conditions
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  117. Mar 2023
  118. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Renal CD81 interacts with sodium potassium 2 chloride cotransporter and sodium chloride cotransporter in rats with lipopolysaccharide-induced preeclampsia
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    Topological regulation of a transmembrane protein by luminal-to-cytosolic retrotranslocation of glycosylated sequence
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    mRNAs encoding IL-12 and a decoy-resistant variant of IL-18 synergize to engineer T cells for efficacious intratumoral adoptive immunotherapy
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    Pyruvate dehydrogenase fuels a critical citrate pool that is essential for Th17 cell effector functions
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    Restoration of Adult Neurogenesis by Intranasal Administration of Gangliosides GD3 and GM1 in The Olfactory Bulb of A53T Alpha-Synuclein-Expressing Parkinson’s-Disease Model Mice
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  123. Feb 2023
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    Chemical inhibition of mitochondrial fission via targeting the DRP1-receptor interaction
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    DDX47, MeCP2, and other functionally heterogeneous factors protect cells from harmful R loops
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    Downregulation of iNOS/NO Promotes Epithelial–Mesenchymal Transition and Metastasis in Colorectal Cancer
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    Glutamine synthetase expression rescues human dendritic cell survival in a glutamine-deprived environment
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  128. Jan 2023
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    GOT1 regulates CD8+ effector and memory T cell generation
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    Artificial extracellular matrix scaffolds of mobile molecules enhance maturation of human stem cell-derived neurons
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  131. Dec 2022
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    The US9-Derived Protein gPTB9TM Modulates APP Processing Without Targeting Secretase Activities
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    The hepatic integrated stress response suppresses the somatotroph axis to control liver damage in nonalcoholic fatty liver disease
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    Regulation of RNA localization during oocyte maturation by dynamic RNA-ER association and remodeling of the ER
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    Mitochondrial cristae architecture protects against mtDNA release and inflammation
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    Raptinal induces Gasdermin E-dependent pyroptosis in naive and therapy-resistant melanoma
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  137. Nov 2022
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    CROCCP2 acts as a human-specific modifier of cilia dynamics and mTOR signaling to promote expansion of cortical progenitors
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    Nonlytic Quasi-Enveloped Hepatovirus Release Is Facilitated by pX Protein Interaction with the E3 Ubiquitin Ligase ITCH
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  140. Oct 2022
  141. 52.53.155.43 52.53.155.43
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  142. www.nature.com www.nature.com
    The autophagy inducer SMER28 attenuates microtubule dynamics mediating neuroprotection
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    Non-canonical inflammasome activation analysis in a mouse model of Citrobacter rodentium infection
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  144. Sep 2022
  145. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multi-omics profiling shows BAP1 loss is associated with upregulated cell adhesion molecules in uveal melanoma
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  146. academic.oup.com academic.oup.com
    Effects of Wnt-β-catenin signaling and sclerostin on the phenotypes of rat pheochromocytoma PC12 cells
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  147. Aug 2022
  148. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    AR-V7 exhibits non-canonical mechanisms of nuclear import and chromatin engagement in castrate-resistant prostate cancer
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  149. www.sciencedirect.com www.sciencedirect.com
    The IRAK4 scaffold integrates TLR4-driven TRIF and MYD88 signaling pathways
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  150. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Paclitaxel in vitro reversibly sensitizes the excitability of IB4(−) and IB4(+) sensory neurons from male and female rats
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  151. Jul 2022
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    The immune checkpoint ICOSLG is a relapse-predicting biomarker and therapeutic target in infant t(4;11) acute lymphoblastic leukemia
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  153. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Slitrk2 deficiency causes hyperactivity with altered vestibular function and serotonergic dysregulation
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  154. Jun 2022
  155. 52.53.155.43 52.53.155.43
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    A function for Ataxia telangiectasia and Rad3-related (ATR) kinase in cytokinetic abscission
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    Counteracting chromatin effects of a splicing-correcting antisense oligonucleotide improves its therapeutic efficacy in spinal muscular atrophy
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    Downregulation of surface AMPA receptor expression in the striatum following prolonged social isolation, a role of mGlu5 receptors
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  159. May 2022
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    Activation of cannabinoid receptors in breast cancer cells improves osteoblast viability in cancer-bone interaction model while reducing breast cancer cell survival and migration
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    Plasmodium parasitophorous vacuole membrane-resident protein UIS4 manipulates host cell actin to avoid parasite elimination
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    Mesothelial cell-derived antigen-presenting cancer-associated fibroblasts induce expansion of regulatory T cells in pancreatic cancer
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  163. Apr 2022
  164. www.sciencedirect.com www.sciencedirect.com
    The TORC1 phosphoproteome in C. elegans reveals roles in transcription and autophagy
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    HIV-1 Vpr drives a tissue residency-like phenotype during selective infection of resting memory T cells
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    Interrogation of cancer gene dependencies reveals paralog interactions of autosome and sex chromosome-encoded genes
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    Protrudin regulates FAK activation, endothelial cell migration and angiogenesis
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    Microbiota-dependent activation of the myeloid calcineurin-NFAT pathway inhibits B7H3- and B7H4-dependent anti-tumor immunity in colorectal cancer
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  169. Mar 2022
  170. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Macrophage network dynamics depend on haptokinesis for optimal local surveillance
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  171. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FBXO47 is essential for preventing the synaptonemal complex from premature disassembly in mouse male meiosis
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    Contribution of cyclooxygenase-1-dependent prostacyclin synthesis to bradykinin-induced dermal extravasation
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    Diacylglycerol kinase η regulates cell proliferation and its levels are elevated by glucocorticoids in undifferentiated neuroblastoma cells
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  174. Feb 2022
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    Poxviruses and paramyxoviruses use a conserved mechanism of STAT1 antagonism to inhibit interferon signaling
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      DOI: 10.1016/j.chom.2022.01.014

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  176. Dec 2021
  177. academic.oup.com academic.oup.com
    Hypothalamic miR-1983 targets insulin receptor beta and the insulin-mediated miR-1983 increase is blocked by metformin
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    SOX10 requirement for melanoma tumor growth is due, in part, to immune-mediated effects
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  179. Nov 2021
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    Lemur tail kinase 1 (LMTK1) regulates the endosomal localization of β-secretase BACE1
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  181. Oct 2021
  182. elifesciences.org elifesciences.org
    HIF1α stabilization in hypoxia is not oxidant-initiated
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  183. Sep 2021
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    Neuroimmunological complications arising from chemotherapy-induced gut toxicity and opioid exposure in female dark agouti rats
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    Homeostatic control of nuclear-encoded mitochondrial gene expression by the histone variant H2A.Z is essential for neuronal survival
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    The prolyl-isomerase PIN1 is essential for nuclear Lamin-B structure and function and protects heterochromatin under mechanical stress
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    FADS2-dependent fatty acid desaturation dictates cellular sensitivity to ferroptosis and permissiveness for hepatitis C virus replication
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    Viral targeting of glioblastoma stem cells with patient-specific genetic and post-translational p53 deregulations
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  189. Aug 2021
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    Skin exposure to UVB light induces a skin-brain-gonad axis and sexual behavior
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    Identification of response signatures for tankyrase inhibitor treatment in tumor cell lines
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    Trajectory analysis unveils Reelin's role in the directed migration of granule cells in the dentate gyrus
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    Perturbation of Iron Metabolism by Cisplatin through Inhibition of Iron Regulatory Protein 2
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    Hepatocyte-Macrophage Acetoacetate Shuttle Protects against Tissue Fibrosis
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    Diarrheal pathogens trigger rapid evolution of the guanylate cyclase-C signaling axis in bats
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    Ablation of neuronal ADAM17 impairs oligodendrocyte differentiation and myelination
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    Mitochondrial cristae-remodeling protein OPA1 in POMC neurons couples Ca2+ homeostasis with adipose tissue lipolysis
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  210. Jul 2021
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    The intramembrane protease SPPL2c promotes male germ cell development by cleaving phospholamban
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    Dopamine D2 receptors are involved in the regulation of fyn and metabotropic glutamate receptor 5 phosphorylation in the rat striatum in vivo
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  218. mbio.asm.org mbio.asm.org
    Pathogenic Escherichia coli Hijacks GTPase-Activated p21-Activated Kinase for Actin Pedestal Formation
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    Glycerol-3-phosphate biosynthesis regenerates cytosolic NAD+ to alleviate mitochondrial disease
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  226. Jun 2021
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    Sperm Behavior and Response to Melatonin under Capacitating Conditions in Three Sheep Breeds Subject to the Equatorial Photoperiod
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  228. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Roles of adenosine A1 receptors in the regulation of SFK activity in the rat forebrain
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    BMP signaling is enhanced intracellularly by FHL3 controlling WNT-dependent spatiotemporal emergence of the neural crest
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      A2066

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