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  1. Aug 2021
  2. www.sciencedirect.com www.sciencedirect.com
    Induced phase separation of mutant NF2 imprisons the cGAS-STING machinery to abrogate antitumor immunity
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    sciencedirect.com/science/article/pii/S1097276521006249
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    Sequential inverse dysregulation of the RNA helicases DDX3X and DDX3Y facilitates MYC-driven lymphomagenesis
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    sciencedirect.com/science/article/pii/S1097276521006250
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    CD63-mediated cloaking of VEGF in small extracellular vesicles contributes to anti-VEGF therapy resistance
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    sciencedirect.com/science/article/pii/S2211124721009839
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    CHIP-dependent regulation of the actin cytoskeleton is linked to neuronal cell membrane integrity
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    ncbi.nlm.nih.gov/pmc/articles/PMC8350547/
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    Sex and brain region specific regulation of serotonin transporter activity in synaptosomes in guanine nucleotide-binding protein G(q) alpha knockout mice
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    Targeting Pin1 renders pancreatic cancer eradicable by synergizing with immunochemotherapy
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    sciencedirect.com/science/article/pii/S0092867421008795
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    3-Hydroxykynurenine Regulates Lipopolysaccharide-Stimulated IL-6 Production and Protects against Endotoxic Shock in Mice
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    Mutations in the transcription factor FOXO1 mimic positive selection signals to promote germinal center B cell expansion and lymphomagenesis
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    sciencedirect.com/science/article/pii/S1074761321002958
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    NAD+ supplement potentiates tumor-killing function by rescuing defective TUB-mediated NAMPT transcription in tumor-infiltrated T cells
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    sciencedirect.com/science/article/pii/S2211124721009463
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    GDF15 mediates the metabolic effects of PPARβ/δ by activating AMPK
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    sciencedirect.com/science/article/pii/S2211124721009293
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    Instability in NAD+ metabolism leads to impaired cardiac mitochondrial function and communication
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    ncbi.nlm.nih.gov/pmc/articles/PMC8331182/
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    Estrogen-related receptor alpha (ERRα) is a key regulator of intestinal homeostasis and protects against colitis
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    The non-canonical target PARP16 contributes to polypharmacology of the PARP inhibitor talazoparib and its synergy with WEE1 inhibitors
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    sciencedirect.com/science/article/pii/S2451945621003482
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    TRAF6 function as a novel co-regulator of Wnt3a target genes in prostate cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC6642315/
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genetic interactions of G-quadruplexes in humans
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  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    Crosstalk control and limits of physiological c-Jun N-terminal kinase activity for cell viability and neurite stability in differentiated PC12 cells - ScienceDirect
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  20. elifesciences.org elifesciences.org
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  21. onlinelibrary.wiley.com onlinelibrary.wiley.com
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      DOI: 10.1002/jnr.23697

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      DOI: 10.1002/jnr.23627

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  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC5980712/
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  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bid maintains mitochondrial cristae structure and function and protects against cardiac disease in an integrative genomics study
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    Temporal Regulation of the Bacterial Metabolite Deoxycholate during Colonic Repair Is Critical for Crypt Regeneration
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    Arginine Methylation by PRMT2 Controls the Functions of the Actin Nucleator Cobl
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    Food Perception Primes Hepatic ER Homeostasis via Melanocortin-Dependent Control of mTOR Activation
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  37. www.jneurosci.org www.jneurosci.org
    Deficiency of CPEB2-Confined Choline Acetyltransferase Expression in the Dorsal Motor Nucleus of Vagus Causes Hyperactivated Parasympathetic Signaling-Associated Bronchoconstriction
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    Autophagy modulates endothelial junctions to restrain neutrophil diapedesis during inflammation
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    sciencedirect.com/science/article/pii/S1074761321002983
  39. www.frontiersin.org www.frontiersin.org
    Piezo2 Knockdown Inhibits Noxious Mechanical Stimulation and NGF-Induced Sensitization in A-Delta Bone Afferent Neurons
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      DOI: 10.3389/fphys.2021.644929

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    frontiersin.org/article/10.3389/fphys.2021.644929/full
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    Conditional Deletion of the L-Type Calcium Channel Cav1.2 in Oligodendrocyte Progenitor Cells Affects Postnatal Myelination in Mice
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  41. www.nature.com www.nature.com
    Stromal induction of BRD4 phosphorylation Results in Chromatin Remodeling and BET inhibitor Resistance in Colorectal Cancer
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    A subset of CB002 xanthine analogs bypass p53-signaling to restore a p53 transcriptome and target an S-phase cell cycle checkpoint in tumors with mutated-p53
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    CACHD1 is an α2δ-Like Protein That Modulates CaV3 Voltage-Gated Calcium Channel Activity
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    The small GTPase Rac1 contributes to extinction of aversive memories of drug withdrawal by facilitating GABA<sub>A</sub> receptor endocytosis in the vmPFC
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    Hormonal and Growth Regulation of Epithelial and Stromal Cells From the Normal and Malignant Endometrium by Pigment Epithelium-Derived Factor
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    Protective effect of exercise training against the progression of Alzheimer’s disease in 3xTg-AD mice
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    Natural Killer Cells Degenerate Intact Sensory Afferents following Nerve Injury
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    Mesothelial Cell HIF1α Expression Is Metabolically Downregulated by Metformin to Prevent Oncogenic Tumor-Stromal Crosstalk
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    KRAS activation in gastric adenocarcinoma stimulates epithelial-to-mesenchymal transition to cancer stem-like cells and promotes metastasis
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    Interleukin 35 ameliorates myocardial ischemia‐reperfusion injury by activating the gp130‐STAT3 axis
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    NMDA receptor blockade ameliorates abnormalities of spike firing of subthalamic nucleus neurons in a parkinsonian nonhuman primate
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    3. scibot 29 Jul 2021
      RRID:AB_476744

      DOI: 10.1002/jnr.24230

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  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Eeyarestatin Compounds Selectively Enhance Sec61-Mediated Ca2+ Leakage from the Endoplasmic Reticulum
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      RRID: AB_476744

      DOI: 10.1016/j.chembiol.2019.01.010

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  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bid maintains mitochondrial cristae structure and function and protects against cardiac disease in an integrative genomics study
    1
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      DOI: 10.7554/eLife.40907

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  87. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Oral administration of a new HRI activator as a new strategy to improve high‐fat‐diet‐induced glucose intolerance, hepatic steatosis, and hypertriglyceridaemia through FGF21
    1
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      β‐actin

      DOI: 10.1111/bph.14678

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      DOI: 10.1016/j.cmet.2018.11.004

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      DOI: 10.1111/jnc.14144

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  91. www.sciencedirect.com www.sciencedirect.com
    Widespread Accumulation of Ribosome-Associated Isolated 3′ UTRs in Neuronal Cell Populations of the Aging Brain
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      DOI: 10.1016/j.celrep.2018.10.094

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  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  96. europepmc.org europepmc.org
    Long-lasting masculinizing effects of postnatal androgens on myelin governed by the brain androgen receptor.
    2
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      RRID:AB_476744

      DOI: 10.1371/journal.pgen.1007049

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      A5441

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  97. academic.oup.com academic.oup.com
    Impact on Experimental Colitis of Vitamin D Receptor Deletion in Intestinal Epithelial or Myeloid Cells
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      AB_476744

      DOI: 10.1210/en.2017-00139

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  98. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Sustained activation of ERK1/2 MAPK in Schwann cells causes corneal neurofibroma
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      DOI: 10.1002/jnr.24067

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  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      DOI: 10.1523/JNEUROSCI.3647-16.2017

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  101. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrative multi-omics analysis identifies a prognostic miRNA signature and a targetable miR-21-3p/TSC2/mTOR axis in metastatic pheochromocytoma/paraganglioma
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      RRID:AB_476744

      DOI: 10.7150/thno.35458

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  102. www.sciencedirect.com www.sciencedirect.com
    BCL11A Haploinsufficiency Causes an Intellectual Disability Syndrome and Dysregulates Transcription
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      AB_47644

      DOI: 10.1016/j.ajhg.2016.05.030

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    VE-Cadherin Is Required for Lymphatic Valve Formation and Maintenance
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      RRID:AB_47674

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      RRID:AB_4767441

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  105. link.springer.com link.springer.com
    Acrylamide Retards the Slow Axonal Transport of Neurofilaments in Rat Cultured Dorsal Root Ganglia Neurons and the Corresponding Mechanisms - Springer
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      AB476744

      DOI: 10.1007/s11064-015-1782-z

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    Acute administration of ucf-101 ameliorates the locomotor impairments induced by a traumatic spinal cord injury
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    Binary pan-cancer classes with distinct vulnerabilities defined by pro- or anti-cancer YAP/TEAD activity
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      RRID:AB_476744

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    Control of gasdermin D oligomerization and pyroptosis by the Ragulator-Rag-mTORC1 pathway
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      RRID:AB_476744

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    Neuroplasticity and inflammatory alterations in the nucleus accumbens are corrected after risperidone treatment in a schizophrenia-related developmental model in rats
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    Protocol for cell preparation and gene delivery in HEK293T and C2C12 cells
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    Site-specific O-GlcNAcylation of Psme3 maintains mouse stem cell pluripotency by impairing P-body homeostasis
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    Dysregulation of GABAA Receptor-Mediated Neurotransmission during the Auditory Cortex Critical Period in the Fragile X Syndrome Mouse Model
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    SREBP-1c impairs ULK1 sulfhydration-mediated autophagic flux to promote hepatic steatosis in high-fat-diet-fed mice
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    Replication gaps are a key determinant of PARP inhibitor synthetic lethality with BRCA deficiency
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  115. Jun 2021
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    Mitochondrial-derived vesicles compensate for loss of LC3-mediated mitophagy
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    Targeting p130Cas- and microtubule-dependent MYC regulation sensitizes pancreatic cancer to ERK MAPK inhibition
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    CX3CL1–CX3CR1 signalling deficiency exacerbates obesity-induced inflammation and insulin resistance in male mice
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    Neuronal Pentraxin 1 Promotes Hypoxic-Ischemic Neuronal Injury by Impairing Mitochondrial Biogenesis via Interactions With Active Bax[6A7] and Mitochondrial Hexokinase II - Md Al Rahim, Shabarish Thatipamula, Giulio M. Pasinetti, Mir Ahamed Hossain, 2021
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    Targeting ribosomal G-quadruplexes with naphthalene-diimides as RNA polymerase I inhibitors for colorectal cancer treatment
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    Nitric Oxide and heme-NO stimulate superoxide production by NADPH Oxidase 5
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    ASPM promotes homologous recombination-mediated DNA repair by safeguarding BRCA1 stability
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  123. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Novel Benzopyrane Derivative Targeting Cancer Cell Metabolic and Survival Pathways
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      DOI: 10.3390/cancers13112840

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  124. www.sciencedirect.com www.sciencedirect.com
    Peroxidation of n-3 and n-6 polyunsaturated fatty acids in the acidic tumor environment leads to ferroptosis-mediated anticancer effects
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      DOI: 10.1016/j.cmet.2021.05.016

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    Target identification for small-molecule discovery in the FOXO3a tumor-suppressor pathway using a biodiverse peptide library
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    TMBIM1 is an inhibitor of adipogenesis and its depletion promotes adipocyte hyperplasia and improves obesity-related metabolic disease
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      DOI: 10.1016/j.cmet.2021.05.014

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    Specific activation of GluN1-N2B NMDA receptors underlies facilitation of cortical spreading depression in a genetic mouse model of migraine with reduced astrocytic glutamate clearance
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    Generation of a homozygous knock-in human embryonic stem cell line expressing SNAP-tagged SOD1
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  129. May 2021
  130. www.nature.com www.nature.com
    Transcriptomics identifies STAT3 as a key regulator of hippocampal gene expression and anhedonia during withdrawal from chronic alcohol exposure
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      DOI: 10.1038/s41398-021-01421-8

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    Adhesion-mediated mechanosignaling forces mitohormesis
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    Implementation of dietary methionine restriction using casein after selective, oxidative deletion of methionine
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    sciencedirect.com/science/article/pii/S2589004221004387
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    Gene-environment interactions mediate stress susceptibility and resilience through the CaMKIIβ/TARPγ-8/AMPAR pathway
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  134. www.tandfonline.com www.tandfonline.com
    CREG1 promotes lysosomal biogenesis and function
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    Virus-mediated inactivation of anti-apoptotic Bcl-2 family members promotes Gasdermin-E-dependent pyroptosis in barrier epithelial cells
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    RIPK1 activation mediates neuroinflammation and disease progression in multiple sclerosis
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    Systematic Functional Analysis of SARS-CoV-2 Proteins Uncovers Viral Innate Immune Antagonists and Remaining Vulnerabilities
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  138. academic.oup.com academic.oup.com
    IGSF1 does not regulate spermatogenesis or modify FSH synthesis in response to inhibins or activins
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      DOI: 10.1210/jendso/bvab023

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  139. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Binge‐Like Ethanol Drinking Activates ALK Signaling and Increases the Expression of STAT3 Target Genes in the Mouse Hippocampus and Prefrontal Cortex
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      DOI: 10.1111/gbb.12729

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    Mitochondrial metabolism is a key regulator of the fibro-inflammatory and adipogenic stromal subpopulations in white adipose tissue
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      DOI: 10.1016/j.stem.2021.01.002

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    A sphingosine kinase 2-mimicking TAT-peptide protects neurons against ischemia-reperfusion injury by activating BNIP3-mediated mitophagy
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    A comprehensive phenotypic CRISPR-Cas9 screen of the ubiquitin pathway uncovers roles of ubiquitin ligases in mitosis
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    TBK1-Mediated DRP1 Targeting Confers Nucleic Acid Sensing to Reprogram Mitochondrial Dynamics and Physiology
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    Inhibition of Glutamine Utilization Synergizes with Immune Checkpoint Inhibitor to Promote Antitumor Immunity
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    Proline Hydroxylation Primes Protein Kinases for Autophosphorylation and Activation
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    Fetal and postnatal zinc restriction: sex differences in the renal renin-angiotensin system of newborn and adult Wistar rats
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    Interleukin-33 Promotes Serotonin Release from Enterochromaffin Cells for Intestinal Homeostasis
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    Small Extracellular Vesicle Regulation of Mitochondrial Dynamics Reprograms a Hypoxic Tumor Microenvironment
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    PIWI proteomics identifies Atari and Pasilla as piRNA biogenesis factors in Aedes mosquitoes
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    Glutamine Metabolism Controls Chondrocyte Identity and Function
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    The Targeting of MRE11 or RAD51 Sensitizes Colorectal Cancer Stem Cells to CHK1 Inhibition
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  152. Apr 2021
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    An IMiD-inducible degron provides reversible regulation for chimeric antigen receptor expression and activity
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    Hypomorph Mutation-Directed Small-Molecule Protein-Protein Interaction Inducers to Restore Mutant SMAD4-Suppressed TGF-β Signaling
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    Integrated Metabolic and Epigenomic Reprograming by H3K27M Mutations in Diffuse Intrinsic Pontine Gliomas
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  156. www.cell.com www.cell.com
    IL6/STAT3 Signaling Hijacks Estrogen Receptor α Enhancers to Drive Breast Cancer Metastasis
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    cell.com/cancer-cell/fulltext/S1535-6108(20)30311-1
  157. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Endoplasmic reticulum oxidoreductase 1 alpha modulates prostate cancer hallmarks
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  158. www.sciencedirect.com www.sciencedirect.com
    Betaine ameliorates schizophrenic traits by functionally compensating for KIF3-based CRMP2 transport
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  159. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Nanog is a promising chemo‐resistant stemness marker and therapeutic target by iron chelators for esophageal cancer
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      anti‐β‐actin

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    onlinelibrary.wiley.com/doi/10.1002/ijc.33544
  160. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Co‐culture of exogenous oligodendrocytes with unmyelinated cerebella: Revisiting ex vivo models and new tools to study myelination
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  161. Mar 2021
  162. academic.oup.com academic.oup.com
    microRNA-483 protects pancreatic beta-cells by targeting ALDH1A3
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      DOI: 10.1210/endocr/bqab031

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    academic.oup.com/endo/article/162/5/bqab031/6132087
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    High KIFC1 expression is associated with poor prognosis in prostate cancer
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    The mitochondrial carrier SFXN1 is critical for complex III integrity and cellular metabolism
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    COX2 regulates senescence secretome composition and senescence surveillance through PGE2
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  166. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Targeting alveolar‐specific succinate dehydrogenase A attenuates pulmonary inflammation during acute lung injury
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  167. elifesciences.org elifesciences.org
    HAT cofactor TRRAP modulates microtubule dynamics via SP1 signaling to prevent neurodegeneration
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  168. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PTEN dephosphorylates Abi1 to promote epithelial morphogenesis
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      DOI: 10.1083/jcb.201910041

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  169. www.sciencedirect.com www.sciencedirect.com
    The SPPL3-Defined Glycosphingolipid Repertoire Orchestrates HLA Class I-Mediated Immune Responses
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  170. link.springer.com link.springer.com
    GRK2 regulates GLP-1R-mediated early phase insulin secretion in vivo
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    Camostat mesylate inhibits SARS-CoV-2 activation by TMPRSS2-related proteases and its metabolite GBPA exerts antiviral activity
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  172. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Ubiquitination and the Proteasome rather than Caspase‐3‐Mediated C‐Terminal Cleavage are Involved in the EAAT2 Degradation by Staurosporine‐Induced Cellular Stress
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  173. Feb 2021
  174. www.sciencedirect.com www.sciencedirect.com
    microRNA-induced translational control of antiviral immunity by the cap-binding protein 4EHP
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    Transneuronal delivery of hyper-interleukin-6 enables functional recovery after severe spinal cord injury in mice
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    The deubiquitinase TRABID stabilises the K29/K48-specific E3 ubiquitin ligase HECTD1
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    FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells
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  178. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Non-Transcriptional and Translational Function of Canonical NF-κB Signaling in Activating ERK1/2 in IL-1β-Induced COX-2 Expression in Synovial Fibroblasts
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  179. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Bicuculline regulated protein synthesis is dependent on homer1 and promotes its interaction with eEF2K through mTORC1 dependent phosphorylation
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  180. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Single-cell RNA-sequencing reveals distinct patterns of cell state heterogeneity in mouse models of breast cancer
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  181. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Heme Oxygenase 1 in Schwann Cells Regulates Peripheral Nerve Degeneration Against Oxidative Stress
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  182. elifesciences.org elifesciences.org
    Elevated synaptic vesicle release probability in synaptophysin/gyrin family quadruple knockouts
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  183. academic.oup.com academic.oup.com
    PKA and AMPK Signaling Pathways Differentially Regulate Luteal Steroidogenesis
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      DOI: 10.1210/endocr/bqab015

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  184. journals.sagepub.com journals.sagepub.com
    ErbB3 is a critical regulator of cytoskeletal dynamics in brain microvascular endothelial cells: Implications for vascular remodeling and blood-brain-barrier modulation - Limin Wu, Mohammad R Islam, Janice Lee, Hajime Takase, Shuzhen Guo, Allison M Andrews, Tetyana P Buzhdygan, Justin Mathew, Wenlu Li, Ken Arai, Eng H Lo, Servio H Ramirez, Josephine Lok, 2021
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  185. journals.plos.org journals.plos.org
    Upshaw-Schulman syndrome-associated ADAMTS13 variants possess proteolytic activity at the surface of endothelial cells and in simulated circulation
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      DOI: 10.1371/journal.pone.0232637

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  186. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A discrete subtype of neural progenitor crucial for cortical folding in the gyrencephalic mammalian brain
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  187. biosignaling.biomedcentral.com biosignaling.biomedcentral.com
    L-plastin Ser5 phosphorylation is modulated by the PI3K/SGK pathway and promotes breast cancer cell invasiveness
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      DOI: 10.1186/s12964-021-00710-5

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  188. www.cell.com www.cell.com
    Negative regulation of AMPK signaling by high glucose via E3 ubiquitin ligase MG53
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  189. www.cell.com www.cell.com
    Mitochondrial Threonyl-tRNA Synthetase TARS2 Is Required for Threonine-Sensitive mTORC1 Activation
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  190. www.cell.com www.cell.com
    In Vivo Evidence for Serine Biosynthesis-Defined Sensitivity of Lung Metastasis, but Not of Primary Breast Tumors, to mTORC1 Inhibition
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  191. www.sciencedirect.com www.sciencedirect.com
    Targeting EphA2 suppresses hepatocellular carcinoma initiation and progression by dual inhibition of JAK1/STAT3 and AKT signaling
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  192. www.jneurosci.org www.jneurosci.org
    Exercise Modulates Chloride Homeostasis after Spinal Cord Injury
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  193. www.cell.com www.cell.com
    Methylglyoxal Scavengers Resensitize KRAS-Mutated Colorectal Tumors to Cetuximab
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  194. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    5’ValCAC tRNA fragment generated as part of a protective angiogenin response provides prognostic value in amyotrophic lateral sclerosis
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  195. www.sciencedirect.com www.sciencedirect.com
    Generation of functional conjunctival epithelium, including goblet cells, from human iPSCs
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  196. Jan 2021
  197. www.frontiersin.org www.frontiersin.org
    AD7c-NTP Impairs Adult Striatal Neurogenesis by Affecting the Biological Function of MeCP2 in APP/PSl Transgenic Mouse Model of Alzheimer's Disease
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  198. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The half-life of the bone-derived hormone osteocalcin is regulated through O-glycosylation in mice, but not in humans
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  199. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Unlike dietary restriction, rapamycin fails to extend lifespan and reduce transcription stress in progeroid DNA repair‐deficient mice
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  200. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mechanical Loading-Driven Tumor Suppression Is Mediated by Lrp5-Dependent and Independent Mechanisms
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      DOI: 10.3390/cancers13020267

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    The ER-embedded UBE2J1/RNF26 ubiquitylation complex exerts spatiotemporal control over the endolysosomal pathway
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  202. www.nature.com www.nature.com
    Voltage-independent GluN2A-type NMDA receptor Ca 2+ signaling promotes audiogenic seizures, attentional and cognitive deficits in mice
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      DOI: 10.1038/s42003-020-01538-4

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    OGT Regulates Hematopoietic Stem Cell Maintenance via PINK1-Dependent Mitophagy
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