43 Matching Annotations
  1. Last 7 days
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    Discovery of a peptide proteolysis-targeting chimera (PROTAC) drug of p300 for prostate cancer therapy
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      DOI: 10.1016/j.ebiom.2024.105212

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    thelancet.com/journals/ebiom/article/PIIS2352-3964(24)00247-0/abstract
  3. Jun 2024
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    MTFP1 controls mitochondrial fusion to regulate inner membrane quality control and maintain mtDNA levels
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      DOI: 10.1016/j.cell.2024.05.017

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    sciencedirect.com/science/article/pii/S0092867424005269
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    A comparative analysis of paxillin and Hic-5 proximity interactomes
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      DOI: 10.1002/cm.21878

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    onlinelibrary.wiley.com/doi/10.1002/cm.21878
  6. May 2024
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    Unraveling ETC complex I function in ferroptosis reveals a potential ferroptosis-inducing therapeutic strategy for LKB1-deficient cancers
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    sciencedirect.com/science/article/pii/S1097276524003241
  8. Mar 2024
  9. www.nature.com www.nature.com
    Clinically-observed FOXA1 mutations upregulate SEMA3C through transcriptional derepression in prostate cancer
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      DOI: 10.1038/s41598-024-57854-w

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  10. elifesciences.org elifesciences.org
    Downregulation of Dickkopf-3, a Wnt antagonist elevated in Alzheimer's disease, restores synapse integrity and memory in a disease mouse model
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      DOI: 10.7554/eLife.89453

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    elifesciences.org/articles/89453
  11. Feb 2024
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    UFL1 ablation in T cells suppresses PD-1 UFMylation to enhance anti-tumor immunity
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    sciencedirect.com/science/article/pii/S1097276524000911
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    In vivo CRISPR knockout screen identifies p47 as a suppressor of HER2+ breast cancer metastasis by regulating NEMO trafficking and autophagy flux
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    sciencedirect.com/science/article/pii/S2211124724001086
  14. Nov 2023
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A genetic variant of the Wnt receptor LRP6 accelerates synapse degeneration during aging and in Alzheimer’s disease
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      DOI: 10.1126/sciadv.abo7421

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    ncbi.nlm.nih.gov/pmc/articles/PMC10624429/
  16. Oct 2023
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    Towards modular engineering of cell signalling: Topographically-textured microparticles induce osteogenesis via activation of canonical hedgehog signalling
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      DOI: 10.1016/j.bioadv.2023.213652

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    sciencedirect.com/science/article/pii/S2772950823003758
  18. Aug 2023
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    S-acylation of the Wnt receptor Frizzled-5 by zDHHC5 controls its cellular localization and synaptogenic activity in the rodent hippocampus
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    sciencedirect.com/science/article/pii/S1534580723003581
  20. Jun 2023
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    Identification of XAF1 as an endogenous AKT inhibitor
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      DOI: 10.1016/j.celrep.2023.112690

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    sciencedirect.com/science/article/pii/S2211124723007015
  22. May 2023
  23. www.nature.com www.nature.com
    ERK and USP5 govern PD-1 homeostasis via deubiquitination to modulate tumor immunotherapy
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      DOI: 10.1038/s41467-023-38605-3

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    nature.com/articles/s41467-023-38605-3
  24. Apr 2023
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    Mechanism of interdigitation formation at apical boundary of MDCK cell
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    sciencedirect.com/science/article/pii/S2589004223006715
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    Shigella IpaA mediates actin bundling through diffusible vinculin oligomers with activation imprint
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    sciencedirect.com/science/article/pii/S2211124723004163
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    A kinome-wide CRISPR screen identifies CK1α as a target to overcome enzalutamide resistance of prostate cancer
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      DOI: 10.1016/j.xcrm.2023.101015

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    sciencedirect.com/science/article/pii/S2666379123001258
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    Autocrine activation of MAPK signaling mediates intrinsic tolerance to androgen deprivation in LY6D prostate cancer cells
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    sciencedirect.com/science/article/pii/S2211124723003881
  29. Jan 2023
  30. www.sciencedirect.com www.sciencedirect.com
    GSNOR deficiency promotes tumor growth via FAK1 S-nitrosylation
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    sciencedirect.com/science/article/pii/S2211124723000086
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pyruvate Kinase M1 Suppresses Development and Progression of Prostate Adenocarcinoma
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      DOI: 10.1158/0008-5472.CAN-21-2352

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    ncbi.nlm.nih.gov/pmc/articles/PMC9256808/
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PDIA3 Activity Promotes Extracellular Accumulation of Proteins Relevant to Basal Breast Cancer Outcomes in Human MDA-MB-A231 Breast Cancer Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC9799142/
  33. Dec 2022
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    USP32-regulated LAMTOR1 ubiquitination impacts mTORC1 activation and autophagy induction
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    sciencedirect.com/science/article/pii/S2211124722015248
  35. Aug 2022
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    ARHGEF9 regulates melanoma morphogenesis in environments with diverse geometry and elasticity by promoting filopodial-driven adhesion
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      DOI: 10.1016/j.isci.2022.104795

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    sciencedirect.com/science/article/pii/S2589004222010677
  37. Jun 2022
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    The focal adhesion protein β-parvin controls cardiomyocyte shape and sarcomere assembly in response to mechanical load
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      DOI: 10.1016/j.cub.2022.05.047

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    sciencedirect.com/science/article/pii/S0960982222008508
  39. Jan 2022
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    Acetylation-dependent regulation of BRAF oncogenic function
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    sciencedirect.com/science/article/pii/S2211124721017629
  41. Aug 2021
  42. academic.oup.com academic.oup.com
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      DOI: 10.1210/js.2018-00170

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    academic.oup.com/jes/article/2/12/1381/5126391
  43. onlinelibrary.wiley.com onlinelibrary.wiley.com
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      DOI: 10.1002/cne.23762

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    onlinelibrary.wiley.com/doi/full/10.1002/cne.23762
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      DOI: 10.1016/j.devcel.2018.11.035

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    sciencedirect.com/science/article/pii/S1534580718310189
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MACF1 links Rapsyn to microtubule- and actin-binding proteins to maintain neuromuscular synapses
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      DOI: 10.1083/jcb.201810023

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    ncbi.nlm.nih.gov/pmc/articles/PMC6504910/
  46. Jul 2021
  47. www.sciencedirect.com www.sciencedirect.com
    Mesothelial Cell HIF1α Expression Is Metabolically Downregulated by Metformin to Prevent Oncogenic Tumor-Stromal Crosstalk
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      DOI: 10.1016/j.celrep.2019.11.079

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    sciencedirect.com/science/article/pii/S2211124719315700
  48. Jun 2021
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KEAP1 deficiency drives glucose dependency and sensitizes lung cancer cells and tumors to GLUT inhibition
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    ncbi.nlm.nih.gov/pmc/articles/PMC8193145/
  50. Apr 2021
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    Discovery of Protein-Protein Interaction Inhibitors by Integrating Protein Engineering and Chemical Screening Platforms
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      DOI: 10.1016/j.chembiol.2020.07.010

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    sciencedirect.com/science/article/pii/S245194562030283X
  52. Oct 2020
  53. www.sciencedirect.com www.sciencedirect.com
    Dynamin-2 Regulates Postsynaptic Cytoskeleton Organization and Neuromuscular Junction Development
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    sciencedirect.com/science/article/pii/S2211124720312997
  54. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Cx43 and Associated Cell Signaling Pathways Regulate Tunneling Nanotubes in Breast Cancer Cells
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      DOI: 10.3390/cancers12102798

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  55. Sep 2020
  56. www.cell.com www.cell.com
    The Unique Cysteine of F-ATP Synthase OSCP Subunit Participates in Modulation of the Permeability Transition Pore
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    cell.com/cell-reports/fulltext/S2211-1247(20)31084-6
  57. www.eneuro.org www.eneuro.org
    Grp94 regulates the recruitment of aneural AChR clusters for the assembly of postsynaptic specializations by modulating ADF/cofilin activity and turnover
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      DOI: 10.1523/ENEURO.0025-20.2020

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  58. elifesciences.org elifesciences.org
    Site-directed MT1-MMP trafficking and surface insertion regulate AChR clustering and remodeling at developing NMJs
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      DOI: 10.7554/eLife.54379

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  59. www.pnas.org www.pnas.org
    JNK-mediated disruption of bile acid homeostasis promotes intrahepatic cholangiocarcinoma
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      DOI: 10.1073/pnas.2002672117

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    pnas.org/content/117/28/16492
  60. Jan 2020
  61. www.sciencedirect.com www.sciencedirect.com
    Small Extracellular Vesicles Are Key Regulators of Non-cell Autonomous Intercellular Communication in Senescence via the Interferon Protein IFITM3
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      DOI: 10.1016/j.celrep.2019.05.095

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    Combination of Hypoglycemia and Metformin Impairs Tumor Metabolic Plasticity and Growth by Modulating the PP2A-GSK3β-MCL-1 Axis
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      DOI: 10.1016/j.ccell.2019.03.007

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    sciencedirect.com/science/article/pii/S1535610819301527
  63. Nov 2018
  64. watermark.silverchair.com watermark.silverchair.com
    js.2018-00170.pdf
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    1. scibot 05 Nov 2018
      RRID:AB_477617

      Curator: @bandrow

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      (Sigma-Aldrich Cat# V4505, RRID:AB_477617)

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      RRID:AB_477617
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    watermark.silverchair.com/js.2018-00170.pdf
  65. Nov 2017
  66. elifesciences.org elifesciences.org
    Multiplex image-based autophagy RNAi screening identifies SMCR8 as ULK1 kinase activity and gene expression regulator
    1
    1. scibot 08 Nov 2017
      AB_477617

      Curator: @kaitlinsung

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      (Sigma-Aldrich Cat# V4505, RRID:AB_477617)

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      RRID:AB_477617 RRIDCUR:Validated
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    elifesciences.org/articles/23063
  67. www.sciencedirect.com www.sciencedirect.com
    Phosphoribosylation of Ubiquitin Promotes Serine Ubiquitination and Impairs Conventional Ubiquitination
    1
    1. scibot 08 Nov 2017
      AB_477617

      Curator: @chewbeccax

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      (Sigma-Aldrich Cat# V4505, RRID:AB_477617)

      SciCrunch record: RRID:AB_477617

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    sciencedirect.com/science/article/pii/S0092867416315914
  68. www.sciencedirect.com www.sciencedirect.com
    Rickettsia Sca4 Reduces Vinculin-Mediated Intercellular Tension to Promote Spread
    1
    1. scibot 08 Nov 2017
      AB_477617

      Curator: @gabimpine

      Resource used:

      (Sigma-Aldrich Cat# V4505, RRID:AB_477617)

      SciCrunch record: RRID:AB_477617

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      RRID:AB_477617 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0092867416312569