119 Matching Annotations
  1. Dec 2025
  2. 54.241.53.176 54.241.53.176
    1-s2.0-S2589004225025532-main-html.html
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    54.241.53.176/5d87d160757da073ce52ccfdd6f8180fdf9242bd/1-s2.0-S2589004225025532-main-html.html
  3. Oct 2025
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Phosphorylation of Plectin by Akt3 Promotes Triple-Negative Breast Cancer Cell Invasive Migration
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    pmc.ncbi.nlm.nih.gov/articles/PMC12508894/
  5. www.biorxiv.org www.biorxiv.org
    Dishevelled drives Wnt-stimulated disassembly of primary cilia through a unique PDZ-mediated binding mode with Daple and Girdin
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    biorxiv.org/content/10.1101/2025.09.26.678488v1
  6. Sep 2025
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Spirodelae Herba ethanol extract attenuates neurotoxicity in hippocampal cells and improves scopolamine-induced cognitive impairment in mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC12422933/
  8. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004225018139-main-html.html
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  9. onlinelibrary.wiley.com onlinelibrary.wiley.com
    GPR65 Functions as a Key Factor of Bone Aging and a Novel Therapeutic Target for Osteoporosis
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    onlinelibrary.wiley.com/doi/10.1111/acel.70212
  10. Jul 2025
  11. www.nature.com www.nature.com
    Neutrophil extracellular trap gene expression signatures identify prognostic and targetable signaling axes for inhibiting pancreatic tumour metastasis
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    nature.com/articles/s42003-025-08440-x
  12. Jun 2025
  13. 52.53.155.43 52.53.155.43
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    52.53.155.43/4c4ba8e26a369e7baf8cacabd22776836e074b0d/PDF-html.html
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    EGFR controls transcriptional and metabolic rewiring in KRASG12D colorectal cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12162862/
  15. May 2025
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Wnt signalosome assembly is governed by conformational flexibility of Axin and by the AP2 clathrin adaptor
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    pmc.ncbi.nlm.nih.gov/articles/PMC12095580/
  17. Mar 2025
  18. www.sciencedirect.com www.sciencedirect.com
    PAI-1-driven SFRP2high cancer-associated fibroblasts hijack the abscopal effect of radioimmunotherapy
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    sciencedirect.com/science/article/pii/S1535610825000765
  19. Feb 2025
  20. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.17475
  21. Dec 2024
  22. www.sciencedirect.com www.sciencedirect.com
    FcRn-dependent IgG accumulation in adipose tissue unmasks obesity pathophysiology
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    sciencedirect.com/science/article/pii/S1550413124004479
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    Mannose metabolism reshapes T cell differentiation to enhance anti-tumor immunity
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    sciencedirect.com/science/article/pii/S1535610824004380
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    Biased signaling by mutant EGFR underlies dependence on PKCα in lung adenocarcinoma
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    sciencedirect.com/science/article/pii/S2211124724013779
  25. Oct 2024
  26. www.sciencedirect.com www.sciencedirect.com
    Nitrous oxide induces hypothermia and TrkB activation: Maintenance of body temperature abolishes antidepressant-like effects in mice
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    sciencedirect.com/science/article/pii/S0028390824003411
  27. Aug 2024
  28. www.embopress.org www.embopress.org
    EDC3 phosphorylation regulates growth and invasion through controlling P‐body formation and dynamics
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    embopress.org/doi/full/10.15252/embr.202050835
  29. pubs.acs.org pubs.acs.org
    Linking Hypothermia and Altered Metabolism with TrkB Activation
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    pubs.acs.org/doi/full/10.1021/acschemneuro.3c00350
  30. elifesciences.org elifesciences.org
    Modelling TFE renal cell carcinoma in mice reveals a critical role of WNT signaling
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    elifesciences.org/content/5/e17047
  31. www.sciencedirect.com www.sciencedirect.com
    Therapeutic application of extracellular vesicular EGFR isoform D as a co-drug to target squamous cell cancers with tyrosine kinase inhibitors
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    sciencedirect.com/science/article/pii/S1534580724004428
  32. Jul 2024
  33. www.embopress.org www.embopress.org
    Non-canonical NF-κB signaling limits the tolerogenic β-catenin-Raldh2 axis in gut dendritic cells to exacerbate intestinal pathologies
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    embopress.org/doi/10.1038/s44318-024-00182-6
  34. May 2024
  35. www.science.org www.science.org
    eEF1A2 promotes PTEN-GSK3β-SCF complex-dependent degradation of Aurora kinase A and is inactivated in breast cancer
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    science.org/doi/10.1126/scisignal.adh4475
  36. Apr 2024
  37. dx.doi.org dx.doi.org
    β-cell insulin resistance plays a causal role in fat-induced β-cell dysfunction in vitro and in vivo
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    dx.doi.org/10.1210/endocr/bqae044
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Creatine and low-dose lithium supplementation separately alter energy expenditure, body mass and adipose metabolism for the promotion of thermogenesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10973579/
  39. Feb 2024
  40. www.sciencedirect.com www.sciencedirect.com
    Trans-omic analysis reveals opposite metabolic dysregulation between feeding and fasting in liver associated with obesity
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    sciencedirect.com/science/article/pii/S2589004224003420
  41. Jul 2023
  42. www.sciencedirect.com www.sciencedirect.com
    mTOR inhibition reprograms cellular proteostasis by regulating eIF3D-mediated selective mRNA translation and promotes cell phenotype switching
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    sciencedirect.com/science/article/pii/S2211124723008793
  43. Jun 2023
  44. www.sciencedirect.com www.sciencedirect.com
    Toward countering muscle and bone loss with spaceflight: GSK3 as a potential target
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    sciencedirect.com/science/article/pii/S2589004223011240
  45. www.sciencedirect.com www.sciencedirect.com
    Endogenous PP2A inhibitor CIP2A degradation by chaperone-mediated autophagy contributes to the antitumor effect of mitochondrial complex I inhibition
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    sciencedirect.com/science/article/pii/S2211124723006277
  46. academic.oup.com academic.oup.com
    Increased fibrosis in white adipose tissue of male and female bGH transgenic mice appears independent of TGF-β action
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    academic.oup.com/endo/article/164/5/bqad038/7069260
  47. May 2023
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PICK1-Deficient Mice Maintain Their Glucose Tolerance During Diet-Induced Obesity
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    ncbi.nlm.nih.gov/pmc/articles/PMC10185814/
  49. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Snail acetylation by autophagy-derived acetyl-coenzyme A promotes invasion and metastasis of KRAS-LKB1 co-mutated lung cancer cells
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    onlinelibrary.wiley.com/doi/10.1002/cac2.12332
  50. www.mdpi.com www.mdpi.com
    GM1 Oligosaccharide Efficacy in Parkinson’s Disease: Protection against MPTP
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    mdpi.com/2227-9059/11/5/1305
  51. Apr 2023
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ablation of palladin in adult heart causes dilated cardiomyopathy associated with intercalated disc abnormalities
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    ncbi.nlm.nih.gov/pmc/articles/PMC10069870/
  53. Mar 2023
  54. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16046
  55. www.sciencedirect.com www.sciencedirect.com
    FAK-mediated phosphorylation at Y464 regulates p85β nuclear translocation to promote tumorigenesis of ccRCC by repressing RB1 expression
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    sciencedirect.com/science/article/pii/S2211124723001997
  56. Feb 2023
  57. www.sciencedirect.com www.sciencedirect.com
    Hexane fraction of Prunus japonica thunb. Seed extract enhances boar sperm motility via CatSper ion channel
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    sciencedirect.com/science/article/pii/S240584402300823X
  58. Jan 2023
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Perturbation of placental protein glycosylation by endoplasmic reticulum stress promotes maladaptation of maternal hepatic glucose metabolism
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    ncbi.nlm.nih.gov/pmc/articles/PMC9843443/
  60. www.sciencedirect.com www.sciencedirect.com
    SLC7A14 imports GABA to lysosomes and impairs hepatic insulin sensitivity via inhibiting mTORC2
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    sciencedirect.com/science/article/pii/S2211124722018885
  61. Dec 2022
  62. www.sciencedirect.com www.sciencedirect.com
    The insulin and IGF signaling pathway sustains breast cancer stem cells by IRS2/PI3K-mediated regulation of MYC
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    sciencedirect.com/science/article/pii/S2211124722016424
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PERIOD 2 Regulates Low Dose Radioprotection via PER2/pGSK3β/β-Catenin/Per2 Loop
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    ncbi.nlm.nih.gov/pmc/articles/PMC9708791/
  64. Sep 2022
  65. www.sciencedirect.com www.sciencedirect.com
    The CX3CL1 intracellular domain exhibits neuroprotection via insulin receptor/ insulin like growth factor receptor signaling
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    sciencedirect.com/science/article/pii/S0021925822009759
  66. www.authorea.com www.authorea.com
    ISX9, a small molecule targeting Axin, activates Wnt/β-catenin signaling and promotes hair regrowth
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    authorea.com/users/503180/articles/582965-isx9-a-small-molecule-targeting-axin-activates-wnt-β-catenin-signaling-and-promotes-hair-regrowth
  67. Aug 2022
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GSK3β Inhibition Is the Molecular Pivot That Underlies the Mir-210-Induced Attenuation of Intrinsic Apoptosis Cascade during Hypoxia
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    ncbi.nlm.nih.gov/pmc/articles/PMC9409400/
  69. Jul 2022
  70. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Altered amyloid precursor protein, tau-regulatory proteins, neuronal numbers and behaviour, but no tau pathology, synaptic and inflammatory changes or memory deficits, at 1-month following repetitive mild traumatic brain injury
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    onlinelibrary.wiley.com/doi/10.1111/ejn.15752
  71. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Potassium channel Kir4.1 regulates oligodendrocyte differentiation via intracellular pH regulation
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    onlinelibrary.wiley.com/doi/10.1002/glia.24240
  72. Jun 2022
  73. journals.lww.com journals.lww.com
    Icariin ameliorates memory deficits through regulating... : Neural Regeneration Research
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    journals.lww.com/nrronline/Fulltext/2023/01000/Icariin_ameliorates_memory_deficits_through.39.aspx
  74. May 2022
  75. www.sciencedirect.com www.sciencedirect.com
    c-JUN inhibits mTORC2 and glucose uptake to promote self-renewal and obesity
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    sciencedirect.com/science/article/pii/S258900422200596X
  76. link.springer.com link.springer.com
    Alzheimer risk gene product Pyk2 suppresses tau phosphorylation and phenotypic effects of tauopathy
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    link.springer.com/article/10.1186/s13024-022-00526-y
  77. www.cell.com www.cell.com
    Systematic discovery of mutation-directed neo-protein-protein interactions in cancer
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    cell.com/cell/fulltext/S0092-8674(22)00461-5
  78. Apr 2022
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transcription factors AP-2α and AP-2β regulate distinct segments of the distal nephron in the mammalian kidney
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    ncbi.nlm.nih.gov/pmc/articles/PMC9038906/
  80. Feb 2022
  81. www.sciencedirect.com www.sciencedirect.com
    A mouse model of inherited choline kinase β-deficiency presents with specific cardiac abnormalities and a predisposition to arrhythmia
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    sciencedirect.com/science/article/pii/S0021925822001569
  82. www.sciencedirect.com www.sciencedirect.com
    Deletion of RNF186 expression suppresses diet-induced hepatic steatosis by regulating insulin activity
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    sciencedirect.com/science/article/pii/S2589004222001298
  83. Sep 2021
  84. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Doxazosin and erlotinib have anticancer effects in the endometrial cancer cell and important roles in ERα and Wnt/β-catenin signaling pathways
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    onlinelibrary.wiley.com/doi/10.1002/jbt.22905
  85. Aug 2021
  86. www.sciencedirect.com www.sciencedirect.com
    The FAPα-activated prodrug Z-GP-DAVLBH inhibits the growth and pulmonary metastasis of osteosarcoma cells by suppressing the AXL pathway
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    sciencedirect.com/science/article/pii/S2211383521003051
  87. www.physiology.org www.physiology.org
    Energy metabolism couples hepatocyte integrin-linked kinase to liver glucoregulation and postabsorptive responses of mice in an age-dependent manner
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    physiology.org/doi/abs/10.1152/ajpendo.00496.2018
  88. onlinelibrary.wiley.com onlinelibrary.wiley.com
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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.14081
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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.14537
  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC6338448/
  91. Jul 2021
  92. academic.oup.com academic.oup.com
    Intrinsic High Aerobic Capacity in Male Rats Protects Against Diet-Induced Insulin Resistance
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    academic.oup.com/endo/article/160/5/1179/5434897
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    sciencedirect.com/science/article/pii/S2352396419301616
  94. www.embopress.org www.embopress.org
    CDK12 drives breast tumor initiation and trastuzumab resistance via WNT and IRS1‐ErbB‐PI3K signaling
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    embopress.org/doi/10.15252/embr.201948058
  95. www.nature.com www.nature.com
    Exogenous C-type natriuretic peptide therapy for impaired skeletal growth in a murine model of glucocorticoid treatment
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    nature.com/articles/s41598-019-44975-w
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    academic.oup.com/endo/article/160/2/377/5235619
  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Ca2+-activated cation channel TRPM4 is a positive regulator of pressure overload-induced cardiac hypertrophy
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    ncbi.nlm.nih.gov/pmc/articles/PMC8245133/
  98. May 2021
  99. www.sciencedirect.com www.sciencedirect.com
    Integrin-Linked Kinase Mediates Therapeutic Resistance of Quiescent CML Stem Cells to Tyrosine Kinase Inhibitors
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    sciencedirect.com/science/article/pii/S1934590920301442
  100. www.sciencedirect.com www.sciencedirect.com
    PSD-95 deficiency alters GABAergic inhibition in the prefrontal cortex
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    sciencedirect.com/science/article/pii/S0028390820303452
  101. www.sciencedirect.com www.sciencedirect.com
    DNA Damage Promotes TMPRSS2-ERG Oncoprotein Destruction and Prostate Cancer Suppression via Signaling Converged by GSK3β and WEE1
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    sciencedirect.com/science/article/pii/S1097276520305190
  102. www.sciencedirect.com www.sciencedirect.com
    An Oncogenic Alteration Creates a Microenvironment that Promotes Tumor Progression by Conferring a Metabolic Advantage to Regulatory T Cells
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    sciencedirect.com/science/article/pii/S1074761320302715
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    AP-2β/KCTD1 Control Distal Nephron Differentiation and Protect against Renal Fibrosis
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    sciencedirect.com/science/article/pii/S1534580720304159
  104. Mar 2021
  105. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15393
  106. Feb 2021
  107. www.sciencedirect.com www.sciencedirect.com
    An acetyl-histone vulnerability in PI3K/AKT inhibition-resistant cancers is targetable by both BET and HDAC inhibitors
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    sciencedirect.com/science/article/pii/S2211124721000577
  108. www.sciencedirect.com www.sciencedirect.com
    Deletion of hippocampal Glucocorticoid receptors unveils sex-biased microRNA expression and neuronal morphology alterations in mice
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    sciencedirect.com/science/article/pii/S235228952100014X
  109. Jan 2021
  110. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Isoform-specific roles for AKT in affective behavior, spatial memory, and extinction related to psychiatric disorders
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    ncbi.nlm.nih.gov/pmc/articles/PMC7787664/
  111. Dec 2020
  112. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Intranasal deferoxamine can improve memory in healthy C57 mice, suggesting a partially non‐disease‐specific pathway of functional neurologic improvement
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    onlinelibrary.wiley.com/doi/10.1002/brb3.1536
  113. Nov 2020
  114. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Effect of Hyperbaric Oxygen Therapy on Acute Liver Injury and Survival in a Rat Cecal Slurry Peritonitis Model
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    pubmed.ncbi.nlm.nih.gov/33203111/
  115. Oct 2020
  116. link.springer.com link.springer.com
    Tideglusib attenuates growth of neuroblastoma cancer stem/progenitor cells in vitro and in vivo by specifically targeting GSK-3β
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    link.springer.com/article/10.1007/s43440-020-00162-7
  117. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC7520443/
  118. Sep 2020
  119. dev.biologists.org dev.biologists.org
    Vessel-derived angiocrine IGF-1 promotes Meckel's cartilage proliferation to drive jaw growth during embryogenesis
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    dev.biologists.org/content/147/11/dev190488
  120. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15182
  121. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A novel compound DBZ ameliorates neuroinflammation in LPS-stimulated microglia and ischemic stroke rats: Role of Akt(Ser473)/GSK3β(Ser9)-mediated Nrf2 activation
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    ncbi.nlm.nih.gov/pmc/articles/PMC7371982/
  122. www.mdpi.com www.mdpi.com
    Melatonin Induces Melanogenesis in Human SK-MEL-1 Melanoma Cells Involving Glycogen Synthase Kinase-3 and Reactive Oxygen Species
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    mdpi.com/1422-0067/21/14/4970
  123. www.sciencedirect.com www.sciencedirect.com
    TNFAIP3 Interacting Protein 3 Overexpression Suppresses Nonalcoholic Steatohepatitis by Blocking TAK1 Activation
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    sciencedirect.com/science/article/pii/S1550413120301224
  124. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Effect of angiotensin II and angiotensin‐(1–7) on proliferation of stem cells from human dental apical papilla
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  128. Jan 2020
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  150. Nov 2017
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