37 Matching Annotations
  1. Sep 2026
  2. www.biorxiv.org www.biorxiv.org
    Membrane PI(4,5)P2 and ErbB2 abundance regulate ErbB receptor oligomerization and kinase activation
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    biorxiv.org/content/10.64898/2026.08.24.746611v3
  3. Aug 2026
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Enhanced HER2 internalization by clathrin-dependent endocytosis in non-small cell lung cancer positive for HER2 mutations
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    pmc.ncbi.nlm.nih.gov/articles/PMC12479963/
  5. Jun 2026
  6. aacrjournals.org aacrjournals.org
    PI3Kα inhibitor and degrader inavolisib can co-opt FGFR2 to enhance responses in patients with PIK3CA-mutated solid tumors and in preclinical models
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    aacrjournals.org/clincancerres/article/32/1/56/771272/PI3K-Inhibitor-and-Degrader-Inavolisib-Can-Co-opt
  7. May 2026
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Loss of payload sensitivity and other mechanisms of resistance to T-DXd in HER2-mutant NSCLC: implications for subsequent responsiveness to HER2 TKIs
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    pmc.ncbi.nlm.nih.gov/articles/PMC13169646/
  9. Apr 2026
  10. www.sciencedirect.com www.sciencedirect.com
    ErbB family receptor dimerization dynamics and dysregulation via long-term single-molecule imaging
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    sciencedirect.com/science/article/pii/S0092867426003995
  11. aacrjournals.org aacrjournals.org
    Targeting tumor microenvironment-derived NRG1-HER2/3 signaling with zenocutuzumab restores sensitivity to AR inhibition in PTEN wild-type prostate cancer
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    aacrjournals.org/mct/article/25/4/662/776472/Targeting-Tumor-Microenvironment-Derived-NRG1-HER2
  12. Jan 2026
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Sevabertinib, a Reversible HER2 Inhibitor with Activity in Lung Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12793832/
  14. Nov 2025
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Increased ErbB2 signaling is an early adaptation to androgen signaling inhibition and persists in castration resistant prostate cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12580767/
  16. Jul 2025
  17. www.sciencedirect.com www.sciencedirect.com
    Therapeutic targeting of syndecan-1 axis overcomes acquired resistance to KRAS-targeted therapy in gastrointestinal cancers
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    sciencedirect.com/science/article/pii/S266637912500326X
  18. Feb 2025
  19. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.17463
  20. Oct 2024
  21. aacrjournals.org aacrjournals.org
    Clinical and Immunologic Responses to a B-Cell Epitope Vaccine in Patients with HER2/neu-Overexpressing Advanced Gastric Cancer—Results from Phase Ib Trial IMU.ACS.001
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    aacrjournals.org/clincancerres/article/27/13/3649/671490/Clinical-and-Immunologic-Responses-to-a-B-Cell
  22. aacrjournals.org aacrjournals.org
    Identification of Predictive ERBB Mutations by Leveraging Publicly Available Cell Line Databases
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    aacrjournals.org/mct/article/20/3/564/92877/Identification-of-Predictive-ERBB-Mutations-by
  23. Sep 2024
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phase II trial of HER-Vaxx, a B cell peptide-based vaccine, in HER2-overexpressing advanced gastric cancer patients under platinum-based chemotherapy (HERIZON)
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    ncbi.nlm.nih.gov/pmc/articles/PMC11393538/
  25. Jul 2024
  26. www.cell.com www.cell.com
    Peptostreptococcus stomatis promotes colonic tumorigenesis and receptor tyrosine kinase inhibitor resistance by activating ERBB2-MAPK
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    cell.com/cell-host-microbe/fulltext/S1931-3128(24)00254-3
  27. Apr 2023
  28. www.nature.com www.nature.com
    Single targeting of MET in EGFR-mutated and MET-amplified non-small cell lung cancer
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    nature.com/articles/s41416-023-02264-4
  29. Dec 2022
  30. www.sciencedirect.com www.sciencedirect.com
    KMT2D deficiency drives lung squamous cell carcinoma and hypersensitivity to RTK-RAS inhibition
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    sciencedirect.com/science/article/pii/S1535610822005621
  31. Jun 2022
  32. aacrjournals.org aacrjournals.org
    NR2F1 is a barrier to dissemination of early stage breast cancer cells.
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    aacrjournals.org/cancerres/article/82/12/2313/699348/NR2F1-Is-a-Barrier-to-Dissemination-of-Early-Stage
  33. May 2022
  34. aacrjournals.org aacrjournals.org
    Triple targeting of HER receptors overcomes heregulin-mediated resistance to EGFR blockade in colorectal cancer
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    aacrjournals.org/mct/article/21/5/799/694777/Triple-Targeting-of-HER-Receptors-Overcomes
  35. Jan 2022
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Triple targeting of breast tumors driven by hormonal receptors and HER2
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    ncbi.nlm.nih.gov/pmc/articles/PMC8742793/
  37. Dec 2021
  38. www.sciencedirect.com www.sciencedirect.com
    MAL2 mediates the formation of stable HER2 signaling complexes within lipid raft-rich membrane protrusions in breast cancer cells
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    sciencedirect.com/science/article/pii/S2211124721016569
  39. Sep 2021
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activity and mechanism of acquired resistance to tarloxotinib in HER2 mutant lung cancer: an in vitro study
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC8435395/
  41. www.sciencedirect.com www.sciencedirect.com
    ERα determines the chemoresistant function of mutant p53 involving the switch between lincRNA-p21 and DDB2 expressions
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    sciencedirect.com/science/article/pii/S2162253121001906
  42. Aug 2021
  43. www.sciencedirect.com www.sciencedirect.com
    Functional diagnostics using fresh uncultured lung tumor cells to guide personalized treatments
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    sciencedirect.com/science/article/pii/S2666379121002275
  44. www.sciencedirect.com www.sciencedirect.com
    Oxidative Stress in Cells with Extra Centrosomes Drives Non-Cell-Autonomous Invasion
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    sciencedirect.com/science/article/pii/S1534580718308803
  45. Jul 2021
  46. www.sciencedirect.com www.sciencedirect.com
    Microenvironment-Mediated Mechanisms of Resistance to HER2 Inhibitors Differ between HER2+ Breast Cancer Subtypes
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    sciencedirect.com/science/article/pii/S2405471218300541
  47. Local file Local file
    CCR-20-3742 3649..3660
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  48. Jun 2021
  49. www.sciencedirect.com www.sciencedirect.com
    Co-occurring gain-of-function mutations in HER2 and HER3 modulate HER2/HER3 activation, oncogenesis, and HER2 inhibitor sensitivity
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    sciencedirect.com/science/article/pii/S1535610821002841
  50. Mar 2021
  51. www.sciencedirect.com www.sciencedirect.com
    Functional cooperation between co-amplified genes promotes aggressive phenotypes of HER2-positive breast cancer
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    sciencedirect.com/science/article/pii/S2211124721001364
  52. www.sciencedirect.com www.sciencedirect.com
    Autophagy blockade limits HER2+ breast cancer tumorigenesis by perturbing HER2 trafficking and promoting release via small extracellular vesicles
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    sciencedirect.com/science/article/pii/S1534580720310224
  53. Sep 2020
  54. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Tumor Microenvironment-Derived NRG1 Promotes Antiandrogen Resistance in Prostate Cancer
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    pubmed.ncbi.nlm.nih.gov/32679108/
  55. Jan 2020
  56. www.sciencedirect.com www.sciencedirect.com
    Pan-Cancer Landscape and Analysis of ERBB2 Mutations Identifies Poziotinib as a Clinically Active Inhibitor and Enhancer of T-DM1 Activity
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    sciencedirect.com/science/article/pii/S1535610819303848
  57. www.sciencedirect.com www.sciencedirect.com
    Functional Redundancy between β1 and β3 Integrin in Activating the IR/Akt/mTORC1 Signaling Axis to Promote ErbB2-Driven Breast Cancer
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    sciencedirect.com/science/article/pii/S2211124719311726
  58. Nov 2018
  59. www.sciencedirect.com www.sciencedirect.com
    EGFR Ligands Differentially Stabilize Receptor Dimers to Specify Signaling Kinetics
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    sciencedirect.com/science/article/pii/S0092867417310668
  60. www.sciencedirect.com www.sciencedirect.com
    Unbiased Combinatorial Screening Identifies a Bispecific IgG1 that Potently Inhibits HER3 Signaling via HER2-Guided Ligand Blockade
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    sciencedirect.com/science/article/pii/S1535610818301740
  61. www.sciencedirect.com www.sciencedirect.com
    Mechanism of Allosteric Coupling into and through the Plasma Membrane by EGFR
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    sciencedirect.com/science/article/pii/S2451945618301193
  62. europepmc.org europepmc.org
    Epidermal Growth Factor Receptor neddylation is regulated by a desmosomal-COP9 (Constitutive Photomorphogenesis 9) signalosome complex.
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    europepmc.org/articles/PMC5663478/