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Jul 2025
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Antibody-mediated TGF-β1 activation for the treatment of diseases caused by deleterious T cell activity

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1. scibot 30 Jul 2025
  
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  DOI: 10.1016/j.celrep.2025.116061
  
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sciencedirect.com/science/article/pii/S2211124725008320
Mar 2025
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ACVR2A attenuation impacts lactate production and hyperglycolytic conditions attracting regulatory T cells in hepatocellular carcinoma

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1. scibot 29 Mar 2025
  
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  DOI: 10.1016/j.xcrm.2025.102038
  
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sciencedirect.com/science/article/pii/S2666379125001119
Feb 2025
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Structures of TGF-β with betaglycan and signaling receptors reveal mechanisms of complex assembly and signaling

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1. scibot 27 Feb 2025
  
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  DOI: 10.1038/s41467-025-56796-9
  
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nature.com/articles/s41467-025-56796-9
Nov 2024
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Integrated multiomic analysis identifies TRIP13 as a mediator of alveolar epithelial type II cell dysfunction in idiopathic pulmonary fibrosis

1
1. scibot 14 Nov 2024
  
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  DOI: 10.1016/j.bbadis.2024.167572
  
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sciencedirect.com/science/article/pii/S0925443924005660
Jul 2024
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Amphiregulin orchestrates the paracrine immune-suppressive function of amniotic-derived cells through its interplay with COX-2/PGE2/EP4 axis

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1. scibot 26 Jul 2024
  
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sciencedirect.com/science/article/pii/S2589004224017334
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Predictive Biomarkers for Response to TGF- β Inhibition in Resensitizing Chemo(radiated) Esophageal Adenocarcinoma

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1. scibot 25 Jul 2024
  
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sciencedirect.com/science/article/pii/S1043661824002603
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RNF185 control of COL3A1 expression limits prostate cancer migration and metastatic potential

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1. scibot 07 Jul 2024
  
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  DOI: 10.1158/1541-7786.MCR-23-0512
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10841372/
May 2024
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Positive and negative feedback regulation of the TGF-β1 explains two equilibrium states in skin aging

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1. scibot 08 May 2024
  
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  DOI: 10.1016/j.isci.2024.109708
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11066433/
Apr 2024
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Endometrial BMP2 Deficiency Impairs ITGB3-Mediated Trophoblast Invasion in Women with Repeated Implantation Failure

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1. scibot 04 Apr 2024
  
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  DOI: 10.1210/endocr/bqae002
  
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academic.oup.com/endo/article-abstract/165/3/bqae002/7513513
Mar 2024
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ALK upregulates POSTN and WNT signaling to drive neuroblastoma

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1. scibot 06 Mar 2024
  
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  DOI: 10.1016/j.celrep.2024.113927
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11101011/
Feb 2024
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Integrative modelling and analysis of signalling crosstalk reveal molecular switches coordinating YAP transcriptional activities

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1. scibot 23 Feb 2024
  
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  DOI: 10.1016/j.isci.2024.109031
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10877689/
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Stromal-derived MAOB promotes prostate cancer growth and progression

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1. scibot 14 Feb 2024
  
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  DOI: 10.1126/sciadv.adi4935
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10857382/
Dec 2023
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ASCL1 characterizes adrenergic neuroblastoma via its pioneer function and cooperation with core regulatory circuit factors

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1. scibot 20 Dec 2023
  
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  DOI: 10.1016/j.celrep.2023.113541
  
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sciencedirect.com/science/article/pii/S221112472301553X
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Smad4 sequestered in SFPQ condensates prevents TGF-β tumor-suppressive signaling

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1. scibot 16 Dec 2023
  
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  DOI: 10.1016/j.devcel.2023.11.020
  
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sciencedirect.com/science/article/pii/S1534580723006184
Oct 2023
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The Dynamics of TGF-β Signaling Are Dictated by Receptor Trafficking via the ESCRT Machinery

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1. scibot 14 Oct 2023
  
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  DOI: 10.1016/j.celrep.2018.10.056
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7615189/
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Typhoid toxin hijacks Wnt5a to establish host senescence and Salmonella infection

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1. scibot 13 Oct 2023
  
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  DOI: 10.1016/j.celrep.2023.113181
  
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sciencedirect.com/science/article/pii/S2211124723011932
Sep 2023
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Signaling-induced systematic repression of miRNAs uncovers cancer vulnerabilities and targeted therapy sensitivity

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1. scibot 30 Sep 2023
  
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  DOI: 10.1016/j.xcrm.2023.101200
  
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Molecular Oncology - 2023 - Horie-html.html

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1. scibot 22 Sep 2023
  
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  DOI: 10.1002/1878-0261.13524
  
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2. scibot 22 Sep 2023
  
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  DOI: 10.1002/1878-0261.13524
  
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52.53.155.43/b5e8e877c627d157950951119edc64db79086ad6/Molecular Oncology - 2023 - Horie-html.html
Aug 2023
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CdGAP is a talin-binding protein and a target of TGF-β signaling that promotes HER2-positive breast cancer growth and metastasis

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1. scibot 10 Aug 2023
  
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  DOI: 10.1016/j.celrep.2023.112936
  
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sciencedirect.com/science/article/pii/S2211124723009476
Jun 2023
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Increased fibrosis in white adipose tissue of male and female bGH transgenic mice appears independent of TGF-β action

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  DOI: 10.1210/endocr/bqad038
  
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academic.oup.com/endo/article/164/5/bqad038/7069260
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5-Azacytidine- and retinoic-acid-induced reprogramming of DCCs into dormancy suppresses metastasis via restored TGF-β-SMAD4 signaling

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1. scibot 02 Jun 2023
  
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sciencedirect.com/science/article/pii/S2211124723005715
May 2023
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BMP4 triggers regulatory circuits specifying the cardiac mesoderm lineage

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1. scibot 19 May 2023
  
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  DOI: 10.1242/dev.201450
  
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52.53.155.43/dd2974174e67d65ed3a779c744ae7b3f60cd7f18/RRID11-html.html
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The ubiquitin-ligase TRAF6 and TGFβ type I receptor form a complex with Aurora kinase B contributing to mitotic progression and cytokinesis in cancer cells

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1. scibot 05 May 2023
  
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  DOI: 10.1016/j.ebiom.2022.104155
  
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sciencedirect.com/science/article/pii/S235239642200336X
Apr 2023
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The UAS thioredoxin-like domain of UBXN7 regulates E3 ubiquitin ligase activity of RNF111/Arkadia

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1. scibot 11 Apr 2023
  
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  DOI: 10.1186/s12915-023-01576-4
  
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link.springer.com/article/10.1186/s12915-023-01576-4
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Site-1 protease inhibits mitochondrial respiration by controlling the TGF-β target gene Mss51

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  DOI: 10.1016/j.celrep.2023.112336
  
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sciencedirect.com/science/article/pii/S2211124723003479
Mar 2023
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Prolyl isomerase Pin1 promotes extracellular matrix production in hepatic stellate cells through regulating formation of the Smad3-TAZ complex

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1. scibot 10 Mar 2023
  
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  DOI: 10.1016/j.yexcr.2023.113544
  
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sciencedirect.com/science/article/pii/S0014482723000915
Feb 2023
biosignaling.biomedcentral.com biosignaling.biomedcentral.com

FKBP12 is a major regulator of ALK2 activity in multiple myeloma cells

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  DOI: 10.1186/s12964-022-01033-9
  
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biosignaling.biomedcentral.com/articles/10.1186/s12964-022-01033-9
Jan 2023
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ZBTB18 restricts chromatin accessibility and prevents transcriptional adaptations that drive metastasis

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1. scibot 20 Jan 2023
  
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  DOI: 10.1126/sciadv.abq3951
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9821869/
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ZBTB18 restricts chromatin accessibility and prevents transcriptional adaptations that drive metastasis

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  DOI: 10.1126/sciadv.abq3951
  
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science.org/doi/10.1126/sciadv.abq3951
Dec 2022
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TGF-β signaling and Creb5 cooperatively regulate Fgf18 to control pharyngeal muscle development

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1. scibot 31 Dec 2022
  
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  DOI: 10.7554/eLife.80405
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9771365/
Sep 2022
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Recombinant production of growth factors for application in cell culture

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  DOI: 10.1016/j.isci.2022.105054
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9489951/
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TGFBR3 supports anoikis through suppressing ATF4 signaling

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1. scibot 22 Sep 2022
  
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  DOI: 10.1242/jcs.258396
  
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journals.biologists.com/jcs/article/135/17/jcs258396/276460/TGFBR3-supports-anoikis-through-suppressing-ATF4
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Modeling human extraembryonic mesoderm cells using naive pluripotent stem cells

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1. scibot 03 Sep 2022
  
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  DOI: 10.1016/j.stem.2022.08.001
  
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sciencedirect.com/science/article/pii/S193459092200337X
May 2022
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Proteolysis of fibrillin-2 microfibrils is essential for normal skeletal development

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1. scibot 11 May 2022
  
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  DOI: 10.7554/eLife.71142
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9064305/
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Mesothelial cell-derived antigen-presenting cancer-associated fibroblasts induce expansion of regulatory T cells in pancreatic cancer

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  DOI: 10.1016/j.ccell.2022.04.011
  
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Lack of Tgfbr1 and Acvr1b synergistically stimulates myofibre hypertrophy and accelerates muscle regeneration

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Identification of Rare Loss-of-Function Genetic Variation Regulating Body Fat Distribution

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Glial Nrf2 signaling mediates the neuroprotection exerted by Gastrodia elata Blume in Lrrk2-G2019S Parkinson’s disease

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Inhibition of TGF-β signaling attenuates disuse-induced trabecular bone loss after spinal cord injury in male mice

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Statins affect cancer cell plasticity with distinct consequences for tumor progression and metastasis

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Adaptations in Hippo-Yap signaling and myofibroblast fate underlie scar-free ear appendage wound healing in spiny mice

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TGFβ signalling is required to maintain pluripotency of human naïve pluripotent stem cells

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The Microbial Metabolite Butyrate Stimulates Bone Formation via T Regulatory Cell-Mediated Regulation of WNT10B Expression

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Cellular Barcoding Identifies Clonal Substitution as a Hallmark of Local Recurrence in a Surgical Model of Head and Neck Squamous Cell Carcinoma

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Cellular Barcoding Identifies Clonal Substitution as a Hallmark of Local Recurrence in a Surgical Model of Head and Neck Squamous Cell Carcinoma

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SMAD-dependent signaling mediates BMP6-induced stimulation of connective tissue growth factor in luteinized human granulosa cells

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Induction of cyclophilin A by influenza A virus infection facilitates group A Streptococcus coinfection

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Inflammation mediates the development of aggressive breast cancer following radiotherapy

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BPS Publications

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Creatine promotes cancer metastasis through activation of Smad2/3

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Astrocyte-derived small extracellular vesicles promote synapse formation via fibulin-2-mediated TGF-β signaling

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A Positive Feedback Loop Between TGFβ and Androgen Receptor Supports Triple-Negative Breast Cancer Anoikis Resistance

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Mutations in SKI in Shprintzen–Goldberg syndrome lead to attenuated TGF-β responses through SKI stabilization

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Capture of Mouse and Human Stem Cells with Features of Formative Pluripotency

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TGFβR-SMAD3 Signaling Induces Resistance to PARP Inhibitors in the Bone Marrow Microenvironment

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Genome-Scale CRISPR Screening in Human Intestinal Organoids Identifies Drivers of TGF-β Resistance

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Smooth Muscle Cell Reprogramming in Aortic Aneurysms

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Muscle-derived Myoglianin regulates Drosophila imaginal disc growth

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Mutant ACVR1 Arrests Glial Cell Differentiation to Drive Tumorigenesis in Pediatric Gliomas

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PRMT1-p53 Pathway Controls Epicardial EMT and Invasion

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Activins as Dual Specificity TGF-β Family Molecules: SMAD-Activation via Activin- and BMP-Type 1 Receptors

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Protective effects of GHK-Cu in bleomycin-induced pulmonary fibrosis via anti-oxidative stress and anti-inflammation pathways

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TGF‐β1 activates RSC96 Schwann cells migration and invasion through MMP‐2 and MMP‐9 activities

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Temporal Control of the TGF-β Signaling Network by Mouse ESC MicroRNA Targets of Different Affinities

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Neural crest-specific deletion of Rbfox2 in mice leads to craniofacial abnormalities including cleft palate

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Untitled document

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Bone morphogenetic protein 2 promotes human trophoblast cell invasion by inducing activin A production

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Twist1 Activation in Muscle Progenitor Cells Causes Muscle Loss Akin to Cancer Cachexia

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Acetyl-CoA Carboxylase 1-Dependent Protein Acetylation Controls Breast Cancer Metastasis and Recurrence

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A Metabolic Basis for Endothelial-to-Mesenchymal Transition

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Myoferlin regulates epithelial cancer cell plasticity and migration through autocrine TGF-β1 signaling

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Pericyte ALK5/TIMP3 Axis Contributes to Endothelial Morphogenesis in the Developing Brain

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Resolving the Combinatorial Complexity of Smad Protein Complex Formation and Its Link to Gene Expression

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Zfp281 is essential for mouse epiblast maturation through transcriptional and epigenetic control of Nodal signaling

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Type XVII collagen coordinates proliferation in the interfollicular epidermis

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