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Sep 2026
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TNFR1 expression on cancer cells mediates immune escape and an immunosuppressive microenvironment

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1. scibot 12 Sep 2026
  
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  DOI: 10.1084/jem.20252080
  
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dx.doi.org/10.1084/jem.20252080
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Cyclin E-CDK2 regulates cancer cell transcriptional program and response to immunotherapy through BRD4

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  DOI: 10.1016/j.molcel.2026.08.007
  
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sciencedirect.com/science/article/pii/S109727652600554X
Aug 2026
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Combined type 2 cytokine blockade enhances PD-1-mediated antitumor immunity

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1. scibot 29 Aug 2026
  
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  DOI: 10.1016/j.celrep.2026.117910
  
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sciencedirect.com/science/article/pii/S2211124726009885
Jul 2026
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Bcl11a orchestrates multilineage integrity in aging hematopoiesis by regulating multipotent progenitor fate decisions

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  DOI: 10.1016/j.celrep.2026.117716
  
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sciencedirect.com/science/article/pii/S2211124726007941
Jun 2026
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The transcription factor Eomes drives a stemness program in CD4+ T cells that promotes anti-tumor immunity in response to immunotherapy

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1. scibot 26 Jun 2026
  
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  DOI: 10.1016/j.immuni.2026.05.018
  
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sciencedirect.com/science/article/pii/S1074761326002293
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The CD49b (ITGA2) collagen receptor excludes CD8+ T cell infiltration in pancreatic ductal adenocarcinoma

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  DOI: 10.1016/j.isci.2026.116500
  
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sciencedirect.com/science/article/pii/S2589004226018754
May 2026
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miR-93-mediated PTEN suppression and CNS-specific T cell exhaustion shape the leukemia niche in infant KMT2A::AFF1+ B-ALL

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  DOI: 10.1016/j.celrep.2026.117353
  
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sciencedirect.com/science/article/pii/S2211124726004316
Apr 2026
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Organ injury in systemic autoimmunity is mediated by stem-like CD8+ T cells arising from tissue-draining lymph nodes

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1. scibot 23 Apr 2026
  
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  DOI: 10.1016/j.immuni.2026.03.022
  
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sciencedirect.com/science/article/pii/S1074761326001330
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A Rasa3-Gαi signaling axis orchestrates B lymphocyte trafficking into and through lymphoid organs

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1. scibot 11 Apr 2026
  
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  DOI: 10.1016/j.celrep.2026.117243
  
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sciencedirect.com/science/article/pii/S2211124726003219
Feb 2026
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Syndecan-1-targeted therapeutic antibody impairs macropinocytosis and elicits antitumor immunity in pancreatic cancer

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1. scibot 19 Feb 2026
  
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  DOI: 10.1016/j.xcrm.2026.102613
  
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sciencedirect.com/science/article/pii/S2666379126000303
Jan 2026
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Remodeling of skull bone channels regulates immune infiltration into the meninges during neuroinflammation

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1. scibot 06 Jan 2026
  
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  DOI: 10.1016/j.immuni.2025.11.019
  
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cell.com/immunity/abstract/S1074-7613(25)00521-7
Dec 2025
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Microbial-derived immunostimulatory small molecule augments anti-PD-1 therapy in lung cancer

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1. scibot 20 Dec 2025
  
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  DOI: 10.1016/j.xcrm.2025.102519
  
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sciencedirect.com:5037/science/article/pii/S2666379125005920
Sep 2025
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ZBP1 pathway promotes tumor immunogenicity in the combination of anti-HER2 therapy and epigenetic therapy

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1. scibot 17 Sep 2025
  
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  DOI: 10.1016/j.celrep.2025.116314
  
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1-s2.0-S2589004225017997-main-html.html

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1. scibot 16 Sep 2025
  
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  DOI: 10.1016/j.isci.2025.113538
  
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52.53.155.43/e30a4682b87b0f107ed8cb8348c0b6cde5bc2c00/1-s2.0-S2589004225017997-main-html.html
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Glycogen synthase kinase-3 is essential for Treg development and function

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1. scibot 12 Sep 2025
  
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  DOI: 10.1016/j.celrep.2025.116256
  
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sciencedirect.com/science/article/pii/S2211124725010277
Aug 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Checkpoint antibody receptor modified ARMed CAR T circumvents the suppressive immunome in GBM

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1. scibot 16 Aug 2025
  
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  DOI: 10.3389/fimmu.2025.1579925
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12351401/
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DNASE1L3-expressing dendritic cells promote CD8+ T cell function and anti-PD-(L)1 therapy efficacy by degrading neutrophil extracellular traps

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1. scibot 15 Aug 2025
  
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  DOI: 10.1016/j.ccell.2025.07.014
  
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cell.com/cancer-cell/abstract/S1535-6108(25)00320-4
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

A Four Amino Acid Intracellular Motif of VISTA Blocks Growth Receptor Signaling in Cancer Cells to Induce Tumor Suppression

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1. scibot 05 Aug 2025
  
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  DOI: 10.1158/0008-5472.CAN-24-4774
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12317733/
Jul 2025
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Differential substrate degradation by super-degron: EGFP in wild-type mouse cells, PD-1 requires CRBN humanization

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1. scibot 15 Jul 2025
  
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  DOI: 10.1016/j.isci.2025.112992
  
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sciencedirect.com/science/article/pii/S2589004225012532
Feb 2025
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AKR1D1 suppresses liver cancer progression by promoting bile acid metabolism-mediated NK cell cytotoxicity

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1. scibot 27 Feb 2025
  
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  DOI: 10.1016/j.cmet.2025.01.011
  
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sciencedirect.com/science/article/pii/S1550413125000117
Jan 2025
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Phenotypic plasticity and increased infiltration of peripheral blood-derived TREM1+ mono-macrophages following radiotherapy in rectal cancer

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1. scibot 14 Jan 2025
  
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  DOI: 10.1016/j.xcrm.2024.101887
  
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sciencedirect.com/science/article/pii/S266637912400658X
Dec 2024
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A pan-family screen of nuclear receptors in immunocytes reveals ligand-dependent inflammasome control

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1. scibot 02 Dec 2024
  
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  DOI: 10.1016/j.immuni.2024.10.010
  
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sciencedirect.com/science/article/pii/S1074761324004904
Nov 2024
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IL-21/IL-21R signaling renders acute myeloid leukemia stem cells more susceptible to cytarabine treatment and CAR T cell therapy

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1. scibot 14 Nov 2024
  
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  DOI: 10.1016/j.xcrm.2024.101826
  
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sciencedirect.com/science/article/pii/S2666379124005974
Aug 2024
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CCL19-producing fibroblasts promote tertiary lymphoid structure formation enhancing anti-tumor IgG response in colorectal cancer liver metastasis

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1. scibot 21 Aug 2024
  
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  DOI: 10.1016/j.ccell.2024.07.006
  
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sciencedirect.com/science/article/pii/S153561082400271X
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High expression of oleoyl-ACP hydrolase underpins life-threatening respiratory viral diseases

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1. scibot 21 Aug 2024
  
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  DOI: 10.1016/j.cell.2024.07.026
  
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sciencedirect.com/science/article/pii/S0092867424008006
Jul 2024
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Preclinical study and phase II trial of adapting low-dose radiotherapy to immunotherapy in small cell lung cancer

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1. scibot 19 Jul 2024
  
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  DOI: 10.1016/j.medj.2024.06.002
  
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sciencedirect.com/science/article/pii/S2666634024002484
May 2024
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One-carbon unit supplementation fuels purine synthesis in tumor-infiltrating T cells and augments checkpoint blockade

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1. scibot 17 May 2024
  
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  DOI: 10.1016/j.chembiol.2024.04.007
  
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sciencedirect.com/science/article/pii/S2451945624001697
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An age-progressive platelet differentiation path from hematopoietic stem cells causes exacerbated thrombosis

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1. scibot 16 May 2024
  
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  DOI: 10.1016/j.cell.2024.04.018
  
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sciencedirect.com/science/article/pii/S0092867424004136
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The histone lysine methyltransferase MLL1 regulates the activation and functional specialization of regulatory T cells

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1. scibot 14 May 2024
  
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  DOI: 10.1016/j.celrep.2024.114222
  
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sciencedirect.com/science/article/pii/S2211124724005503
Mar 2024
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Adipose stem cells control obesity-induced T cell infiltration into adipose tissue

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1. scibot 19 Mar 2024
  
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  DOI: 10.1016/j.celrep.2024.113963
  
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sciencedirect.com/science/article/pii/S2211124724002912
Jan 2024
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Bispecific dendritic-T cell engager potentiates anti-tumor immunity

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1. scibot 19 Jan 2024
  
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  DOI: 10.1016/j.cell.2023.12.011
  
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sciencedirect.com/science/article/pii/S0092867423013430
Oct 2023
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Targeting VCP potentiates immune checkpoint therapy for colorectal cancer

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1. scibot 27 Oct 2023
  
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  DOI: 10.1016/j.celrep.2023.113318
  
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sciencedirect.com/science/article/pii/S221112472301330X
52.53.155.43 52.53.155.43

CD4+ T cell-derived IL21 regulates stem cell fate in acute myeloid leukemia by activation of p38-MAPK signaling

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1. scibot 20 Oct 2023
  
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  DOI: 10.1101/2023.09.01.555931
  
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52.53.155.43/af30fe5b925ee191151336cec774a7057661b188/2023.09.01.555931v1.full-html.html
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Lymph node–resident dendritic cells drive TH2 cell development involving MARCH1

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1. scibot 17 Oct 2023
  
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  DOI: 10.1126/sciimmunol.abh0707
  
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science.org/doi/10.1126/sciimmunol.abh0707
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Systematic investigation of mitochondrial transfer between cancer cells and T cells at single-cell resolution

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1. scibot 13 Oct 2023
  
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  DOI: 10.1016/j.ccell.2023.09.003
  
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sciencedirect.com/science/article/pii/S1535610823003197
Aug 2023
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A MYC-controlled redox switch protects B lymphoma cells from EGR1-dependent apoptosis

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CD39 inhibition and VISTA blockade may overcome radiotherapy resistance by targeting exhausted CD8+ T cells and immunosuppressive myeloid cells

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Transcription factor TCF-1 regulates the functions, but not the development, of lymphoid tissue inducer subsets in different tissues

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Jul 2023
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The splicing isoform Foxp3Δ2 differentially regulates tTreg and pTreg homeostasis

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Jun 2023
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Neuroprotective protein ADNP-dependent histone remodeling complex promotes T helper 2 immune cell differentiation

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Apr 2023
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An optimized IL-12-Fc expands its therapeutic window, achieving strong activity against mouse tumors at tolerable drug doses

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Targeting protein tyrosine phosphatases for CDK6-induced immunotherapy resistance

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A neutrophil response linked to tumor control in immunotherapy

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Arresting microbiome development limits immune system maturation and resistance to infection in mice

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Tumor PD-L1 engages myeloid PD-1 to suppress type I interferon to impair cytotoxic T lymphocyte recruitment

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Fc glycoengineering of a PD-L1 antibody harnesses Fcγ receptors for increased antitumor efficacy

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Feb 2023
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Flow cytometry and immunohistochemistry of the mouse dural meninges for immunological and virological assessments

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MHC class II-restricted antigen presentation is required to prevent dysfunction of cytotoxic T cells by blood-borne myeloids in brain tumors

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T cell-derived interleukin-22 drives the expression of CD155 by cancer cells to suppress NK cell function and promote metastasis

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Nov 2022
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T cell deficiency precipitates antibody evasion and emergence of neurovirulent polyomavirus

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Sep 2022
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Vaccination-based immunotherapy to target profibrotic cells in liver and lung

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ATF3 and CH25H regulate effector trogocytosis and anti-tumor activities of endogenous and immunotherapeutic cytotoxic T lymphocytes

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Androgen receptor-mediated CD8+ T cell stemness programs drive sex differences in antitumor immunity

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Intracellular infection and immune system cues rewire adipocytes to acquire immune function

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Lymph node–resident dendritic cells drive TH2 cell development involving MARCH1

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Mar 2022
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AXL targeting restores PD-1 blockade sensitivity of STK11/LKB1 mutant NSCLC through expansion of TCF1+ CD8 T cells

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Comparative transcriptomic analysis reveals translationally relevant processes in mouse models of malaria

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Sep 2021
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CD4 T cell help prevents CD8 T cell exhaustion and promotes control of Mycobacterium tuberculosis infection

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Notch-induced endoplasmic reticulum-associated degradation governs mouse thymocyte β−selection

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Untitled document

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Untitled document

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Untitled document

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Quantitative Interactomics in Primary T Cells Provides a Rationale for Concomitant PD-1 and BTLA Coinhibitor Blockade in Cancer Immunotherapy

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Obesity-Linked PPARγ S273 Phosphorylation Promotes Insulin Resistance through Growth Differentiation Factor 3

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Functional Genomics Identifies Metabolic Vulnerabilities in Pancreatic Cancer

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Sirt2 Inhibition Enhances Metabolic Fitness and Effector Functions of Tumor-Reactive T Cells

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Enteric viruses evoke broad host immune responses resembling those elicited by the bacterial microbiome

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Telomere Stress Potentiates STING-Dependent Anti-tumor Immunity

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Gut microbial metabolites facilitate anticancer therapy efficacy by modulating cytotoxic CD8+ T cell immunity

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  DOI: 10.1016/j.cmet.2021.03.002
  
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Autophagy in T cells from aged donors is maintained by spermidine and correlates with function and vaccine responses

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  DOI: 10.7554/eLife.57950
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7744099/
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Targeting Lymph Node Niches Enhances Type 1 Immune Responses to Immunization

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  DOI: 10.1016/j.celrep.2020.107679
  
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Coordinated Viral Control by Cytotoxic Lymphocytes Ensures Optimal Adaptive NK Cell Responses

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  DOI: 10.1016/j.celrep.2020.108186
  
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An Immunologic Mode of Multigenerational Transmission Governs a Gut Treg Setpoint

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  DOI: 10.1016/j.cell.2020.04.030
  
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Type I Interferons Suppress Anti-parasitic Immunity and Can Be Targeted to Improve Treatment of Visceral Leishmaniasis

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  DOI: 10.1016/j.celrep.2020.01.099
  
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Bmal1 integrates mitochondrial metabolism and macrophage activation

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  DOI: 10.7554/eLife.54090
  
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Defects in Antiviral T Cell Responses Inflicted by Aging-Associated miR-181a Deficiency

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  DOI: 10.1016/j.celrep.2019.10.044
  
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PD-1 Imposes Qualitative Control of Cellular Transcriptomes in Response to T Cell Activation

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  DOI: 10.1016/j.molcel.2019.12.012
  
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Polyamines Control eIF5A Hypusination, TFEB Translation, and Autophagy to Reverse B Cell Senescence

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  DOI: 10.1016/j.molcel.2019.08.005
  
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Epithelial NOTCH Signaling Rewires the Tumor Microenvironment of Colorectal Cancer to Drive Poor-Prognosis Subtypes and Metastasis

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Untitled document

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Transcription Factor IRF8 Orchestrates the Adaptive Natural Killer Cell Response

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Nov 2017
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Enhancing CD8+ T Cell Fatty Acid Catabolism within a Metabolically Challenging Tumor Microenvironment Increases the Efficacy of Melanoma Immunotherapy

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