118 Matching Annotations
  1. Dec 2024
  2. www.sciencedirect.com www.sciencedirect.com
    IL-17A/CEBPβ/OPN/LYVE-1 axis inhibits anti-tumor immunity by promoting tumor-associated tissue-resident macrophages
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    1. scibot 12 Dec 2024
      RRID:AB_493715

      DOI: 10.1016/j.celrep.2024.115039

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    sciencedirect.com/science/article/pii/S2211124724013901
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    Type I IFN-mediated NET release promotes Mycobacterium tuberculosis replication and is associated with granuloma caseation
    1
    1. scibot 05 Dec 2024
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      DOI: 10.1016/j.chom.2024.11.008

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    sciencedirect.com/science/article/pii/S1931312824004396
  4. Nov 2024
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Ablation of PC1/3 in POMC-expressing Tissues but not in Immune Cells Induces Sepsis Hypersensitivity
    1
    1. scibot 07 Nov 2024
      RRID:AB_493715

      DOI: 10.1210/jendso/bvae171

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    pmc.ncbi.nlm.nih.gov/articles/PMC11492489/
  6. Oct 2024
  7. www.sciencedirect.com www.sciencedirect.com
    Stress triggers irritable bowel syndrome with diarrhea through a spermidine-mediated decline in type I interferon
    1
    1. scibot 04 Oct 2024
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      DOI: 10.1016/j.cmet.2024.09.002

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    sciencedirect.com/science/article/pii/S1550413124003668
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Macrophage-mediated myelin recycling fuels brain cancer malignancy
    1
    1. scibot 02 Oct 2024
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      DOI: 10.1016/j.cell.2024.07.030

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    ncbi.nlm.nih.gov/pmc/articles/PMC11429458/
  9. Sep 2024
  10. www.sciencedirect.com www.sciencedirect.com
    Dynamic allostery drives autocrine and paracrine TGF-β signaling
    1
    1. scibot 17 Sep 2024
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      DOI: 10.1016/j.cell.2024.08.036

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    sciencedirect.com/science/article/pii/S0092867424009656
  11. Aug 2024
  12. www.sciencedirect.com www.sciencedirect.com
    Interleukin-21 engineering enhances NK cell activity against glioblastoma via CEBPD
    1
    1. scibot 21 Aug 2024
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      DOI: 10.1016/j.ccell.2024.07.007

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    sciencedirect.com/science/article/pii/S1535610824002721
  13. Jul 2024
  14. www.sciencedirect.com www.sciencedirect.com
    Splenic marginal zone B cells restrict Mycobacterium tuberculosis infection by shaping the cytokine pattern and cell-mediated immunity
    1
    1. scibot 19 Jul 2024
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      DOI: 10.1016/j.celrep.2024.114426

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    sciencedirect.com/science/article/pii/S2211124724007551
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Investigation of a fluorescent reporter microenvironment niche labeling strategy in experimental brain metastasis
    1
    1. scibot 18 Jul 2024
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      DOI: 10.1016/j.isci.2024.110284

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    ncbi.nlm.nih.gov/pmc/articles/PMC11261144/
  16. Jun 2024
  17. link.springer.com link.springer.com
    Fasting-mimicking diet remodels gut microbiota and suppresses colorectal cancer progression
    1
    1. scibot 28 Jun 2024
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      DOI: 10.1038/s41522-024-00520-w

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    link.springer.com/article/10.1038/s41522-024-00520-w
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Aging Lacrimal Gland of Female C57BL/6J Mice Exhibits Multinucleate Macrophage Infiltration Associated With Lipid Dysregulation
    1
    1. scibot 09 Jun 2024
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      DOI: 10.1167/iovs.65.6.1

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    ncbi.nlm.nih.gov/pmc/articles/PMC11156205/
  19. www.sciencedirect.com www.sciencedirect.com
    Clonal hematopoiesis driven by mutated DNMT3A promotes inflammatory bone loss
    1
    1. scibot 05 Jun 2024
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      DOI: 10.1016/j.cell.2024.05.003

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    sciencedirect.com/science/article/pii/S0092867424004926
  20. May 2024
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Novel Spirocyclic Dimer, SpiD3, Targets Chronic Lymphocytic Leukemia Survival Pathways with Potent Preclinical Effects
    1
    1. scibot 24 May 2024
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      DOI: 10.1158/2767-9764.CRC-24-0071

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    ncbi.nlm.nih.gov/pmc/articles/PMC11110724/
  22. www.sciencedirect.com www.sciencedirect.com
    Distinct roles of TREM2 in central nervous system cancers and peripheral cancers
    1
    1. scibot 24 May 2024
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      DOI: 10.1016/j.ccell.2024.05.001

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    sciencedirect.com/science/article/pii/S1535610824001624
  23. www.sciencedirect.com www.sciencedirect.com
    Single-cell proteomics and transcriptomics capture eosinophil development and identify the role of IL-5 in their lineage transit amplification
    1
    1. scibot 23 May 2024
      RRID:AB_493715

      DOI: 10.1016/j.immuni.2024.04.027

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    sciencedirect.com/science/article/pii/S1074761324002322
  24. www.sciencedirect.com www.sciencedirect.com
    Immunotherapy-activated T cells recruit and skewlate-stage activated M1-like macrophagesthat are critical for therapeutic efficacy
    1
    1. scibot 17 May 2024
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      DOI: 10.1016/j.ccell.2024.04.011

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    sciencedirect.com/science/article/pii/S1535610824001351
  25. 52.53.155.43 52.53.155.43
    2024.03.02.583119v1.full-html.html
    1
    1. scibot 16 May 2024
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      DOI: 10.1128/iai.00004-13

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    52.53.155.43/6a71e4d7810341343df9a7e9b0f30ef2509d5125/2024.03.02.583119v1.full-html.html
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    IL-7-primed bystander CD8 tumor-infiltrating lymphocytes optimize the antitumor efficacy of T cell engager immunotherapy
    1
    1. scibot 14 May 2024
      RRID:AB_493715

      DOI: 10.1016/j.xcrm.2024.101567

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    sciencedirect.com/science/article/pii/S2666379124002593
  27. www.biorxiv.org www.biorxiv.org
    The Gut Microbiome Controls Liver Tumors via the Vagus Nerve
    1
    1. scibot 09 May 2024
      BioLegend, catalogue #103128

      DOI: 10.1101/2024.01.23.576951

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    biorxiv.org/content/10.1101/2024.01.23.576951v1
  28. www.sciencedirect.com www.sciencedirect.com
    Chemoradiotherapy-induced ACKR2+ tumor cells drive CD8+ T cell senescence and cervical cancer recurrence
    1
    1. scibot 09 May 2024
      RRID:AB_493715

      DOI: 10.1016/j.xcrm.2024.101550

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    sciencedirect.com/science/article/pii/S2666379124002428
  29. www.sciencedirect.com www.sciencedirect.com
    Monoclonal antibody-mediated neutralization of Clostridioides difficile toxin does not diminish induction of the protective innate immune response to infection
    1
    1. scibot 07 May 2024
      103128

      DOI: 10.1016/j.anaerobe.2024.102859

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    sciencedirect.com/science/article/pii/S1075996424000428
  30. www.sciencedirect.com www.sciencedirect.com
    Glucose-driven histone lactylation promotes the immunosuppressive activity of monocyte-derived macrophages in glioblastoma
    1
    1. scibot 07 May 2024
      RRID:AB_493715

      DOI: 10.1016/j.immuni.2024.04.006

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    sciencedirect.com/science/article/pii/S1074761324002115
  31. Apr 2024
  32. www.sciencedirect.com www.sciencedirect.com
    CD80 on skin stem cells promotes local expansion of regulatory T cells upon injury to orchestrate repair within an inflammatory environment
    1
    1. scibot 30 Apr 2024
      RRID:AB_493715

      DOI: 10.1016/j.immuni.2024.04.003

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    sciencedirect.com/science/article/pii/S1074761324002085
  33. www.sciencedirect.com www.sciencedirect.com
    Jagged2 targeting in lung cancer activates anti-tumor immunity via Notch-induced functional reprogramming of tumor-associated macrophages
    1
    1. scibot 18 Apr 2024
      RRID:AB_493715

      DOI: 10.1016/j.immuni.2024.03.020

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    sciencedirect.com/science/article/pii/S1074761324001419
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    A conserved antigen induces respiratory Th17-mediated broad serotype protection against pneumococcal superinfection
    1
    1. scibot 11 Apr 2024
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      DOI: 10.1016/j.chom.2024.02.002

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    sciencedirect.com/science/article/pii/S1931312824000374
  35. Mar 2024
  36. www.sciencedirect.com www.sciencedirect.com
    Microbial metabolite enhances immunotherapy efficacy by modulating T cell stemness in pan-cancer
    1
    1. scibot 15 Mar 2024
      RRID:AB_493715

      DOI: 10.1016/j.cell.2024.02.022

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    sciencedirect.com/science/article/pii/S0092867424002241
  37. Jan 2024
  38. www.sciencedirect.com www.sciencedirect.com
    Fc-fused IL-7 provides broad antiviral effects against respiratory virus infections through IL-17A-producing pulmonary innate-like T cells
    1
    1. scibot 21 Jan 2024
      RRID:AB_493715

      DOI: 10.1016/j.xcrm.2023.101362

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    sciencedirect.com/science/article/pii/S2666379123005797
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    Interrogation of endothelial and mural cells in brain metastasis reveals key immune-regulatory mechanisms
    1
    1. scibot 19 Jan 2024
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      DOI: 10.1016/j.ccell.2023.12.018

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    sciencedirect.com/science/article/pii/S1535610823004464
  40. www.sciencedirect.com www.sciencedirect.com
    CpsA mediates infection of recruited lung myeloid cells by Mycobacterium tuberculosis
    1
    1. scibot 12 Jan 2024
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      DOI: 10.1016/j.celrep.2023.113607

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    sciencedirect.com/science/article/pii/S2211124723016194
  41. www.sciencedirect.com www.sciencedirect.com
    Interferon-stimulated neutrophils as a predictor of immunotherapy response
    1
    1. scibot 09 Jan 2024
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      DOI: 10.1016/j.ccell.2023.12.005

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    sciencedirect.com/science/article/pii/S1535610823004336
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    Characterization of immune populations in the tumor microenvironment of diffuse midline glioma orthotopic mouse models by flow cytometry
    1
    1. scibot 07 Jan 2024
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      DOI: 10.1016/j.xpro.2023.102803

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    sciencedirect.com/science/article/pii/S2666166723007700
  43. www.sciencedirect.com www.sciencedirect.com
    An exhausted-like microglial population accumulates in aged and APOE4 genotype Alzheimer’s brains
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    1. scibot 06 Jan 2024
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      DOI: 10.1016/j.immuni.2023.12.001

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    sciencedirect.com/science/article/pii/S1074761323005320
  44. Dec 2023
  45. www.sciencedirect.com www.sciencedirect.com
    Direct assessment of nitrative stress in lipid environments: Applications of a designer lipid-based biosensor for peroxynitrite
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    1. scibot 21 Dec 2023
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      DOI: 10.1016/j.isci.2023.108567

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    sciencedirect.com/science/article/pii/S2589004223026445
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    The MHC-E peptide ligands for checkpoint CD94/NKG2A are governed by inflammatory signals, whereas LILRB1/2 receptors are peptide indifferent
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    1. scibot 20 Dec 2023
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      DOI: 10.1016/j.celrep.2023.113516

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    sciencedirect.com/science/article/pii/S2211124723015280
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    Circulating senescent myeloid cells infiltrate the brain and cause neurodegeneration in histiocytic disorders
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    1. scibot 17 Dec 2023
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      DOI: 10.1016/j.immuni.2023.11.011

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    sciencedirect.com/science/article/pii/S1074761323004934
  48. Nov 2023
  49. www.sciencedirect.com www.sciencedirect.com
    The antitumor activities of anti-CD47 antibodies require Fc-FcγR interactions
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    1. scibot 28 Nov 2023
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      DOI: 10.1016/j.ccell.2023.10.007

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    sciencedirect.com/science/article/pii/S153561082300363X
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    S. aureus drives itch and scratch-induced skin damage through a V8 protease-PAR1 axis
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    1. scibot 28 Nov 2023
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      DOI: 10.1016/j.cell.2023.10.019

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    sciencedirect.com/science/article/pii/S0092867423011649
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    Isolation of single cells from individual mouse ovaries for flow cytometry and functional analysis
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    1. scibot 18 Nov 2023
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      DOI: 10.1016/j.xpro.2023.102710

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    sciencedirect.com/science/article/pii/S2666166723006779
  52. 52.53.155.43 52.53.155.43
    Lactobacillus acidophilus-derived indole lactic acid reverses colitis susceptibility in cesarean-born offspring via activation of AhR
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    1. scibot 04 Nov 2023
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      DOI: 10.1016/j.isci.2023.108279

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    52.53.155.43/6d3cb369970d6af9ee4a6737bc5efd3ec5f8e04b/1-s2.0-S2589004223023568-main-html.html
  53. Oct 2023
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Uptake of tumor-derived microparticles induces metabolic reprogramming of macrophages in the early metastatic lung
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    TIM-3 blockade in diffuse intrinsic pontine glioma models promotes tumor regression and antitumor immune memory
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    Ketogenesis promotes tolerance to Pseudomonas aeruginosa pulmonary infection
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  57. Sep 2023
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    Regulatory T cells require IL6 receptor alpha signaling to control skeletal muscle function and regeneration
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    The local microenvironment drives activation of neutrophils in human brain tumors
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  60. Aug 2023
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    Adrenergic nerves regulate intestinal regeneration through IL-22 signaling from type 3 innate lymphoid cells
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    Characterizing CD4 T cell differentiation in mouse small intestine using T cell transfer, lamina propria preparation, and flow cytometry
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    Humanized mouse liver reveals endothelial control of essential hepatic metabolic functions
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  64. Jul 2023
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    Kynurenine monooxygenase regulates inflammation during critical illness and recovery in experimental acute pancreatitis
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    High-fat-diet-associated intestinal microbiota exacerbates psoriasis-like inflammation by enhancing systemic γδ T cell IL-17 production
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    Constitutively active autophagy in macrophages dampens inflammation through metabolic and post-transcriptional regulation of cytokine production
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  68. Jun 2023
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    Vectored immunoprophylaxis and treatment of SARS-CoV-2 infection in a preclinical model
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    Quantitative control of Ets1 dosage by a multi-enhancer hub promotes Th1 cell differentiation and protects from allergic inflammation
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  71. May 2023
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    Helicobacter spp. are prevalent in wild mice and protect from lethal Citrobacter rodentium infection in the absence of adaptive immunity
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    IL-10 production by granulocytes promotes Staphylococcus aureus craniotomy infection
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  74. Apr 2023
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    Methotrexate suppresses psoriatic skin inflammation by inhibiting muropeptide transporter SLC46A2 activity
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  76. Mar 2023
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    Saturated fatty acids dampen the immunogenicity of cancer by suppressing STING
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    m6A-driven SF3B1 translation control steers splicing to direct genome integrity and leukemogenesis
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    Original research: Invasive margin tissue-resident macrophages of high CD163 expression impede responses to T cell-based immunotherapy
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    Endoplasmic reticulum stress in the intestinal epithelium initiates purine metabolite synthesis and promotes Th17 cell differentiation in the gut
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  81. Feb 2023
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    Repression of the aryl-hydrocarbon receptor prevents oxidative stress and ferroptosis of intestinal intraepithelial lymphocytes
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    A Cre-deleter specific for embryo-derived brain macrophages reveals distinct features of microglia and border macrophages
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    Zika virus spreads through infection of lymph node-resident macrophages
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    Senescence Rewires Microenvironment Sensing to Facilitate Antitumor Immunity
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  86. Dec 2022
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    Clostridium butyricum-induced ω-3 fatty acid 18-HEPE elicits anti-influenza virus pneumonia effects through interferon-λ upregulation
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    Lipid-laden lung mesenchymal cells foster breast cancer metastasis via metabolic reprogramming of tumor cells and natural killer cells
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  89. Oct 2022
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  91. Sep 2022
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    Ablation of the endoplasmic reticulum stress kinase PERK induces paraptosis and type I interferon to promote anti-tumor T cell responses
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  93. Aug 2022
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    Rapid GPR183-mediated recruitment of eosinophils to the lung after Mycobacterium tuberculosis infection
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    Lung fibroblasts facilitate pre-metastatic niche formation by remodeling the local immune microenvironment
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  96. Jun 2022
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    Optimal target saturation of ligand-blocking anti-GITR antibody IBI37G5 dictates FcγR-independent GITR agonism and antitumor activity
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  98. May 2022
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    Interleukin-6 blockade abrogates immunotherapy toxicity and promotes tumor immunity
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  100. Apr 2022
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    TNF-α sculpts a maturation process in vivo by pruning tolerogenic dendritic cells
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    Klebsiella pneumoniae induces host metabolic stress that promotes tolerance to pulmonary infection
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    Binding of LAG-3 to stable peptide-MHC class II limits T cell function and suppresses autoimmunity and anti-cancer immunity
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    Specification of fetal liver endothelial progenitors to functional zonated adult sinusoids requires c-Maf induction
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  105. Mar 2022
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    Type 1 innate lymphoid cells regulate the onset of Toxoplasma gondii-induced neuroinflammation
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    Lactylation-driven METTL3-mediated RNA m6A modification promotes immunosuppression of tumor-infiltrating myeloid cells
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  108. Feb 2022
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    An adjuvant strategy enabled by modulation of the physical properties of microbial ligands expands antigen immunogenicity
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  110. Dec 2021
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  113. Nov 2021
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  121. Jul 2021
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    Natural Tr1-like cells do not confer long-term tolerogenic memory
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  125. Jun 2021
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    Endothelial Tpl2 regulates vascular barrier function via JNK-mediated degradation of claudin-5 promoting neuroinflammation or tumor metastasis
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    Endogenous Glucocorticoid Signaling Regulates CD8+ T Cell Differentiation and Development of Dysfunction in the Tumor Microenvironment
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    Multi-tissue single-cell analysis deconstructs the complex programs of mouse natural killer and type 1 innate lymphoid cells in tissues and circulation
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    Optogenetic activation of local colonic sympathetic innervations attenuates colitis by limiting immune cell extravasation
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  134. Apr 2021
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    Gut microbial metabolites facilitate anticancer therapy efficacy by modulating cytotoxic CD8+ T cell immunity
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  139. Jan 2021
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    Distinct developmental pathways from blood monocytes generate human lung macrophage diversity
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  141. Nov 2020
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    IL-15 superagonist N-803 improves IFNγ production and killing of leukemia and ovarian cancer cells by CD34 +  progenitor-derived NK cells
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  143. Oct 2020
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    Infiltrating Hematogenous Macrophages Aggregate Around β-Amyloid Plaques in an Age- and Sex-Dependent Manner in a Mouse Model of Alzheimer Disease
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  145. Sep 2020
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    UVB-Induced Tumor Heterogeneity Diminishes Immune Response in Melanoma
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    Innate Sensing through Mesenchymal TLR4/MyD88 Signals Promotes Spontaneous Intestinal Tumorigenesis
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  154. Nov 2018
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    Lung Single-Cell Signaling Interaction Map Reveals Basophil Role in Macrophage Imprinting
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    The Majority of CD45– Ter119– CD31– Bone Marrow Cell Fraction Is of Hematopoietic Origin and Contains Erythroid and Lymphoid Progenitors
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    Intestinal Dysmotility Syndromes following Systemic Infection by Flaviviruses
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    Pseudouridylation of tRNA-Derived Fragments Steers Translational Control in Stem Cells
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    Nrf2-Mediated Fibroblast Reprogramming Drives Cellular Senescence by Targeting the Matrisome
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    The ghrelin/GOAT system regulates obesity-induced inflammation in male mice.
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    Enhancement of IFNγ Production by Distinct Commensals Ameliorates Salmonella-Induced Disease
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    Identification of Nascent Memory CD8 T Cells and Modeling of Their Ontogeny
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