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May 2026
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Genotoxicity profiling reveals distinct platform-and cell type-specific effects in therapeutic gene editing for genetic hyperinflammation

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  DOI: 10.1016/j.stem.2026.04.014
  
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sciencedirect.com/science/article/pii/S1934590926001542
Mar 2026
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Foxp3 and BATF cooperatively direct cis-regulatory programs and gene expression for effector Treg cell differentiation

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  DOI: 10.1016/j.immuni.2026.03.005
  
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Regulatory T cell-derived TGF-β signaling governs the differentiation and maintenance of tumor-infiltrating bystander CD8+ T cells

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sciencedirect.com/science/article/pii/S2211124726002676
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Oncolytic virotherapy potentiates chemo-PD-1 immunotherapy by engaging chemo-resistant bystander CD8+ T cells

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  DOI: 10.1136/jitc-2026-014897
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12970110/
Oct 2025
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RAF-independent MEK mutations drive refractory histiocytic neoplasms but respond to ERK inhibition

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  DOI: 10.1016/j.ccell.2025.09.014
  
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sciencedirect.com/science/article/pii/S1535610825004064
Aug 2025
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2025.08.13.669552v1.full-html.html

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  DOI: 10.1101/2025.08.13.669552
  
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52.53.155.43/cbef6d49734833e21d46745b8a2764b4c745ed76/2025.08.13.669552v1.full-html.html
Jul 2025
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Mitochondrial complex IV remodeling in tumor-associated macrophages amplifies interferon signaling and promotes anti-tumor immunity

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May 2025
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Enhancer-driven gene regulatory networks reveal transcription factors governing T cell adaptation and differentiation in the tumor microenvironment

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  DOI: 10.1016/j.immuni.2025.04.030
  
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sciencedirect.com/science/article/pii/S1074761325001931
Jan 2025
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Fiber- and acetate-mediated modulation of MHC-II expression on intestinal epithelium protects from Clostridioides difficile infection

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sciencedirect.com/science/article/pii/S1931312824004840
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Splenic fibroblasts control marginal zone B cell movement and function via two distinct Notch2-dependent regulatory programs

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  DOI: 10.1016/j.immuni.2024.12.003
  
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sciencedirect.com/science/article/pii/S1074761324005673
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Transplantation of gasdermin pores by extracellular vesicles propagates pyroptosis to bystander cells

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  DOI: 10.1016/j.cell.2024.11.018
  
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sciencedirect.com/science/article/pii/S0092867424013345
Dec 2024
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Durable lymphocyte subset elimination upon a single dose of AAV-delivered depletion antibody dissects immune control of chronic viral infection

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  DOI: 10.1016/j.immuni.2024.11.021
  
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sciencedirect.com/science/article/pii/S1074761324005363
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Inflammation switches the chemoattractant requirements for naive lymphocyte entry into lymph nodes

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1. scibot 21 Dec 2024
  
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  DOI: 10.1016/j.cell.2024.11.031
  
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sciencedirect.com/science/article/pii/S0092867424013473
Sep 2024
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The transcription regulator ID3 maintains tumor-specific memory CD8+ T cells in draining lymph nodes during tumorigenesis

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Aug 2024
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LAG-3 sustains TOX expression and regulates the CD94/NKG2-Qa-1b axis to govern exhausted CD8 T cell NK receptor expression and cytotoxicity

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1. scibot 20 Aug 2024
  
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  DOI: 10.1016/j.cell.2024.07.018
  
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sciencedirect.com/science/article/pii/S0092867424007785
May 2024
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SDHAF1 confers metabolic resilience to aging hematopoietic stem cells by promoting mitochondrial ATP production

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  DOI: 10.1016/j.stem.2024.04.023
  
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sciencedirect.com/science/article/pii/S1934590924001760
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Immunotherapy-activated T cells recruit and skewlate-stage activated M1-like macrophagesthat are critical for therapeutic efficacy

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1. scibot 17 May 2024
  
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  DOI: 10.1016/j.ccell.2024.04.011
  
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sciencedirect.com/science/article/pii/S1535610824001351
Apr 2024
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ER-associated degradation adapter Sel1L is required for CD8+ T cell function and memory formation following acute viral infection

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1. scibot 30 Apr 2024
  
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  DOI: 10.1016/j.celrep.2024.114156
  
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sciencedirect.com/science/article/pii/S2211124724004844
elifesciences.org elifesciences.org

Context-dependent modification of PFKFB3 in hematopoietic stem cells promotes anaerobic glycolysis and ensures stress hematopoiesis

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  DOI: 10.7554/eLife.87674
  
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elifesciences.org/articles/87674
Mar 2024
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IKK2 controls the inflammatory potential of tissue-resident regulatory T cells in a murine gain of function model

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  DOI: 10.1038/s41467-024-45870-3
  
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nature.com/articles/s41467-024-45870-3
Dec 2023
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Stat5 opposes the transcription factor Tox and rewires exhausted CD8+ T cells toward durable effector-like states during chronic antigen exposure

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Oct 2023
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Lymph node–resident dendritic cells drive TH2 cell development involving MARCH1

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  DOI: 10.1126/sciimmunol.abh0707
  
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science.org/doi/10.1126/sciimmunol.abh0707
Sep 2023
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ALKBH5 modulates hematopoietic stem and progenitor cell energy metabolism through m6A modification-mediated RNA stability control

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  DOI: 10.1016/j.celrep.2023.113163
  
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Antigen receptor signaling and cell death resistance controls intestinal humoral response zonation

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Jul 2023
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Obesity-induced dysregulation of skin-resident PPARγ+ Treg cells promotes IL-17A-mediated psoriatic inflammation

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Jun 2023
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Platelets and mast cells promote pathogenic eosinophil recruitment during invasive fungal infection via the 5-HIAA-GPR35 ligand-receptor system

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Mar 2023
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Original research: Invasive margin tissue-resident macrophages of high CD163 expression impede responses to T cell-based immunotherapy

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  DOI: 10.1136/jitc-2022-006433
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10016286/
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B cell receptor signaling in germinal centers prolongs survival and primes B cells for selection

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  DOI: 10.1016/j.immuni.2023.02.003
  
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Sep 2022
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Inhibition of Th1 activation and differentiation by dietary guar gum ameliorates experimental autoimmune encephalomyelitis

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sciencedirect.com/science/article/pii/S2211124722011561
Apr 2022
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Lymph node–resident dendritic cells drive TH2 cell development involving MARCH1

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  DOI: 10.1126/sciimmunol.abh0707
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8736284/
Sep 2021
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Effector T cell responses unleashed by regulatory T cell ablation exacerbate oral squamous cell carcinoma

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  DOI: 10.1016/j.xcrm.2021.100399
  
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sciencedirect.com/science/article/pii/S2666379121002573
Aug 2021
europepmc.org europepmc.org

Untitled document

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  DOI: 10.7554/eLife.41258
  
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europepmc.org/articles/PMC6298771/
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Untitled document

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  DOI: 10.1016/j.celrep.2018.10.042
  
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sciencedirect.com/science/article/pii/S2211124718316310
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Untitled document

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  DOI: 10.1016/j.celrep.2018.10.042
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6289055/
Jul 2021
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Interferon-α-producing plasmacytoid dendritic cells drive the loss of adipose tissue regulatory T cells during obesity

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1. scibot 13 Jul 2021
  
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  DOI: 10.1016/j.cmet.2021.06.007
  
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sciencedirect.com/science/article/pii/S1550413121002771
Apr 2021
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In vivo CD8+ T cell CRISPR screening reveals control by Fli1 in infection and cancer

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1. scibot 11 Apr 2021
  
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  DOI: 10.1016/j.cell.2021.02.019
  
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Oct 2020
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In Situ Maturation and Tissue Adaptation of Type 2 Innate Lymphoid Cell Progenitors

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1. scibot 01 Oct 2020
  
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  DOI: 10.1016/j.immuni.2020.09.002
  
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Sep 2020
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Murine HSCs contribute actively to native hematopoiesis but with reduced differentiation capacity upon aging

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1. scibot 23 Sep 2020
  
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  DOI: 10.7554/eLife.41258
  
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Discovery of surrogate agonists for visceral fat Treg cells that modulate metabolic indices in vivo

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1. scibot 17 Sep 2020
  
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  DOI: 10.7554/eLife.58463
  
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Developmental Relationships of Four Exhausted CD8+ T Cell Subsets Reveals Underlying Transcriptional and Epigenetic Landscape Control Mechanisms

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1. scibot 17 Sep 2020
  
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  DOI: 10.1016/j.immuni.2020.04.014
  
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Type I Interferons Suppress Anti-parasitic Immunity and Can Be Targeted to Improve Treatment of Visceral Leishmaniasis

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1. scibot 16 Sep 2020
  
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  DOI: 10.1016/j.celrep.2020.01.099
  
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The PD-1 Pathway Regulates Development and Function of Memory CD8+ T Cells following Respiratory Viral Infection

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1. scibot 09 Sep 2020
  
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  DOI: 10.1016/j.celrep.2020.107827
  
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Tissue-Specific Macrophage Responses to Remote Injury Impact the Outcome of Subsequent Local Immune Challenge

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.immuni.2019.10.010
  
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Environmental Optimization Enables Maintenance of Quiescent Hematopoietic Stem Cells Ex Vivo

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.celrep.2019.06.008
  
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Class-Switch Recombination Occurs Infrequently in Germinal Centers

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.immuni.2019.07.001
  
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TCF-1-Centered Transcriptional Network Drives an Effector versus Exhausted CD8 T Cell-Fate Decision

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.immuni.2019.09.013
  
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Stress-Induced Changes in Bone Marrow Stromal Cell Populations Revealed through Single-Cell Protein Expression Mapping

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.stem.2019.06.003
  
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Methyltransferase Nsd2 Ensures Germinal Center Selection by Promoting Adhesive Interactions between B Cells and Follicular Dendritic Cells

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1. scibot 13 Jan 2020
  
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Untitled document

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1. scibot 13 Jan 2020
  
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  DOI: 10.7554/eLife.41258
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6298771/
Nov 2018
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KLRG1+ Effector CD8+ T Cells Lose KLRG1, Differentiate into All Memory T Cell Lineages, and Convey Enhanced Protective Immunity

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1. scibot 05 Nov 2018
  
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Nov 2017
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Analyses of a Mutant Foxp3 Allele Reveal BATF as a Critical Transcription Factor in the Differentiation and Accumulation of Tissue Regulatory T Cells

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1. scibot 08 Nov 2017
  
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