Hypothesis

10 Matching Annotations

Apr 2026
www.science.org www.science.org

Selective targeting of mutant huntingtin intron 1 improves rescue provided by antisense oligonucleotides in Huntington’s disease mice

1
1. scibot 02 Apr 2026
  
  in Public
  
  RRID:AB_532270
  
  DOI: 10.1126/scitranslmed.adv0702
  
  Resource: (Sigma-Aldrich Cat# P1874, RRID:AB_532270)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_532270
  
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  RRID:AB_532270
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RRID:AB_532270

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scibot

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science.org/doi/10.1126/scitranslmed.adv0702
May 2024
www.sciencedirect.com www.sciencedirect.com

The anti-leprosy drug clofazimine reduces polyQ toxicity through activation of PPARγ

1
1. scibot 03 May 2024
  
  in Public
  
  RRID:AB_532270
  
  DOI: 10.1016/j.ebiom.2024.105124
  
  Resource: (Sigma-Aldrich Cat# P1874, RRID:AB_532270)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_532270
  
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  RRID:AB_532270
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RRID:AB_532270

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scibot

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sciencedirect.com/science/article/pii/S2352396424001592
Oct 2021
www.sciencedirect.com www.sciencedirect.com

Gene bookmarking by the heat shock transcription factor programs the insulin-like signaling pathway

1
1. scibot 14 Oct 2021
  
  in Public
  
  RRID:AB_532270
  
  DOI: 10.1016/j.molcel.2021.09.022
  
  Resource: (Sigma-Aldrich Cat# P1874, RRID:AB_532270)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_532270
  
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  RRID:AB_532270
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RRID:AB_532270

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scibot

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sciencedirect.com/science/article/pii/S1097276521007759
Sep 2021
academic.oup.com academic.oup.com

Immortalized striatal precursor neurons from Huntington’s disease patient-derived iPS cells as a platform for target identification and screening for experimental therapeutics

1
1. scibot 24 Sep 2021
  
  in Public
  
  P1874
  
  DOI: 10.1093/hmg/ddab200
  
  Resource: (Sigma-Aldrich Cat# P1874, RRID:AB_532270)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_532270
  
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  RRIDCUR:Missing RRID:AB_532270
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RRID:AB_532270

RRIDCUR:Missing

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scibot

URL

academic.oup.com/hmg/advance-article/doi/10.1093/hmg/ddab200/6325571
Aug 2021
onlinelibrary.wiley.com onlinelibrary.wiley.com

Phenotype onset in Huntington’s disease knock‐in mice is correlated with the incomplete splicing of the mutant huntingtin gene

1
1. scibot 14 Aug 2021
  
  in Public
  
  RRID:AB_532270
  
  DOI: 10.1002/jnr.24493
  
  Resource: (Sigma-Aldrich Cat# P1874, RRID:AB_532270)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_532270
  
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  RRID:AB_532270
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onlinelibrary.wiley.com/doi/abs/10.1002/jnr.24493
Apr 2021
www.sciencedirect.com www.sciencedirect.com

Pathological polyQ expansion does not alter the conformation of the Huntingtin-HAP40 complex

1
1. scibot 28 Apr 2021
  
  in Public
  
  AB_532270
  
  DOI: 10.1016/j.str.2021.04.003
  
  Resource: (Sigma-Aldrich Cat# P1874, RRID:AB_532270)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_532270
  
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  RRID:AB_532270
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sciencedirect.com/science/article/pii/S0969212621001192
Jan 2020
www.nature.com www.nature.com

Assessing average somatic CAG repeat instability at the protein level

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_532270
  
  DOI: 10.1038/s41598-019-55202-x
  
  Resource: (Sigma-Aldrich Cat# P1874, RRID:AB_532270)
  
  Curator: @evieth
  
  SciCrunch record: RRID:AB_532270
  
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  RRID:AB_532270 RRIDCUR:Validated
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RRID:AB_532270

RRIDCUR:Validated

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scibot

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nature.com/articles/s41598-019-55202-x
www.sciencedirect.com www.sciencedirect.com

Huntington’s Disease Pathogenesis Is Modified In Vivo by Alfy/Wdfy3 and Selective Macroautophagy

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_532270
  
  DOI: 10.1016/j.neuron.2019.12.003
  
  Resource: (Sigma-Aldrich Cat# P1874, RRID:AB_532270)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_532270
  
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  RRID:AB_532270 RRIDCUR:Validated
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RRID:AB_532270

RRIDCUR:Validated

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scibot

URL

sciencedirect.com/science/article/pii/S0896627319310451
Nov 2018
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A Method for the Acute and Rapid Degradation of Endogenous Proteins

2
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:AB_532270
  
  Curator: @evieth
  
  Resource used:
  
  (Sigma-Aldrich Cat# P1874, RRID:AB_532270)
  
  SciCrunch record: RRID:AB_532270
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_532270 RRIDCUR:Validated
2. scibot 05 Nov 2018
  
  in Public
  
  RRID:AB_532270
  
  Curator: @evieth
  
  Resource used:
  
  (Sigma-Aldrich Cat# P1874, RRID:AB_532270)
  
  SciCrunch record: RRID:AB_532270
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_532270 RRIDCUR:Validated
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RRID:AB_532270

RRIDCUR:Validated

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC5733393/