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Oct 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

A disease-associated PPP2R3C-MAP3K1 phospho-regulatory module controls centrosome function

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1. scibot 23 Oct 2025
  
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  DOI: 10.1016/j.cub.2024.08.058
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11496028/
Sep 2025
52.53.155.43 52.53.155.43

rajeevan-et-al-2025-aurora-a-regulates-the-material-property-of-spindle-poles-to-orchestrate-nuclear-organization-at-html.html

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52.53.155.43/3d79dc73d22a782c26af2bd1e412c87bbe5039ed/rajeevan-et-al-2025-aurora-a-regulates-the-material-property-of-spindle-poles-to-orchestrate-nuclear-organization-at-html.html
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Cholangiocytes’ Primary Cilia Regulate DNA Damage Response and Repair

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1. scibot 07 Sep 2025
  
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  DOI: 10.1152/ajpgi.00055.2025
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12409734/
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Role of Serotonin on Gene Expression and Physiology in Human Cytotrophoblasts and Placenta

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1. scibot 05 Sep 2025
  
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  DOI: 10.1210/endocr/bqaf124
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12399332/
Jul 2025
elifesciences.org elifesciences.org

Planar cell polarity coordination in a cnidarian embryo provides clues to animal body axis evolution

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1. scibot 03 Jul 2025
  
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  DOI: 10.7554/eLife.104508
  
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elifesciences.org/articles/104508
Jun 2025
www.sciencedirect.com www.sciencedirect.com

Hyperacute response proteins synthesized on γ-tubulin-FTO-MARK4 translation microdomains regulate cancer’s acute stress response

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  DOI: 10.1016/j.celrep.2025.115871
  
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sciencedirect.com/science/article/pii/S2211124725006424
May 2025
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Neuroimmune signaling mediates astrocytic nucleocytoplasmic disruptions and stress granule formation associated with TDP-43 pathology

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1. scibot 18 May 2025
  
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sciencedirect.com/science/article/pii/S096999612500155X
Mar 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Forebrain Eml1 depletion reveals early centrosomal dysfunction causing subcortical heterotopia

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1. scibot 28 Mar 2025
  
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  DOI: 10.1083/jcb.202310157
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11450323/
Feb 2025
onlinelibrary.wiley.com onlinelibrary.wiley.com

Taming interleukin-12: Engineering of bispecific antibody-based IL-12 mimetics with biased agonism capacities

1
1. scibot 22 Feb 2025
  
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  DOI: 10.1002/pro.70072
  
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onlinelibrary.wiley.com/doi/10.1002/pro.70072
Dec 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The ribotoxic stress response drives acute inflammation, cell death, and epidermal thickening in UV-irradiated skin in vivo

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1. scibot 02 Dec 2024
  
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  DOI: 10.1016/j.molcel.2024.10.044
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11671030/
Nov 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Drosophila p53 tumor suppressor directly activates conserved asymmetric stem cell division regulators

1
1. scibot 15 Nov 2024
  
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  DOI: 10.1016/j.isci.2024.111118
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11546965/
Sep 2024
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Partial closure of the γ-tubulin ring complex by CDK5RAP2 activates microtubule nucleation

1
1. scibot 26 Sep 2024
  
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  DOI: 10.1016/j.devcel.2024.09.002
  
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sciencedirect.com/science/article/pii/S1534580724005306
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Starvation-induced phosphorylation activates gasdermin A to initiate pyroptosis

1
1. scibot 11 Sep 2024
  
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  DOI: 10.1016/j.celrep.2024.114728
  
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sciencedirect.com/science/article/pii/S2211124724010799
Aug 2024
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Force-induced dephosphorylation activates the cochaperone BAG3 to coordinate protein homeostasis and membrane traffic

1
1. scibot 27 Aug 2024
  
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  DOI: 10.1016/j.cub.2024.07.088
  
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sciencedirect.com/science/article/pii/S0960982224010273
Jul 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Sperm Head-Tail Linkage Requires Restriction of Pericentriolar Material to the Proximal Centriole End

1
1. scibot 16 Jul 2024
  
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  DOI: 10.1016/j.devcel.2020.02.006
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7170007/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Hippocampal astrocytes induce sex-dimorphic effects on memory

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1. scibot 14 Jul 2024
  
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  DOI: 10.1016/j.celrep.2024.114278
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11234507/
www.cell.com www.cell.com

ADP-ribosylome analysis reveals homogeneous DNA-damage-induced serine ADP-ribosylation across wild-type and BRCA-mutant breast cancer cell lines

1
1. scibot 12 Jul 2024
  
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  DOI: 10.1016/j.celrep.2024.114433
  
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cell.com/cell-reports/fulltext/S2211-1247(24)00762-9
Apr 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A disease-associated PPP2R3C-MAP3K1 phospho-regulatory module controls centrosome function

1
1. scibot 30 Apr 2024
  
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  RRID:AB_532292
  
  DOI: 10.1101/2024.04.02.587836
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11014585/
Mar 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Ana1/CEP295 is an essential player in the centrosome maintenance program regulated by Polo kinase and the PCM

1
1. scibot 02 Mar 2024
  
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  DOI: 10.1038/s44319-023-00020-6
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10897187/
Feb 2024
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Kin17 regulates proper cortical localization of Miranda in Drosophila neuroblasts by regulating Flfl expression

1
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  DOI: 10.1016/j.celrep.2024.113823
  
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sciencedirect.com/science/article/pii/S2211124724001517
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Diffusible fraction of niche BMP ligand safeguards stem-cell differentiation

1
1. scibot 11 Feb 2024
  
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  DOI: 10.1038/s41467-024-45408-7
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10850516/
Jan 2024
www.science.org www.science.org

Astrocytic TDP-43 dysregulation impairs memory by modulating antiviral pathways and interferon-inducible chemokines

1
1. scibot 18 Jan 2024
  
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  DOI: 10.1126/sciadv.ade1282
  
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science.org/doi/10.1126/sciadv.ade1282
Aug 2023
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Golgi-dependent reactivation and regeneration of Drosophila quiescent neural stem cells

1
1. scibot 11 Aug 2023
  
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  DOI: 10.1016/j.devcel.2023.07.010
  
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sciencedirect.com/science/article/pii/S1534580723003568
Jul 2023
www.nature.com www.nature.com

Inhibition of AXL receptor tyrosine kinase enhances brown adipose tissue functionality in mice

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  DOI: 10.1038/s41467-023-39715-8
  
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nature.com/articles/s41467-023-39715-8
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Glyoxal-based fixation of Drosophila embryos for immunofluorescence staining and RNA in situ hybridization

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1. scibot 08 Jul 2023
  
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  DOI: 10.1016/j.xpro.2023.102385
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10345161/
Apr 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Astrocytic TDP-43 dysregulation impairs memory by modulating antiviral pathways and interferon-inducible chemokines

1
1. scibot 27 Apr 2023
  
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  DOI: 10.1126/sciadv.ade1282
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10115456/
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Coordination of tissue homeostasis and growth by the Scribble-α-Catenin-Septate junction complex

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1. scibot 21 Apr 2023
  
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  DOI: 10.1016/j.isci.2023.106490
  
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sciencedirect.com/science/article/pii/S2589004223005679
Feb 2023
academic.oup.com academic.oup.com

Activation of PDGF signaling in the adult muscle stem cell niche in patients with type 2 diabetes mellitus

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1. scibot 25 Feb 2023
  
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  DOI: 10.1210/clinem/dgad041
  
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academic.oup.com/jcem/advance-article/doi/10.1210/clinem/dgad041/7005464
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Microglia reactivity entails microtubule remodeling from acentrosomal to centrosomal arrays

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  DOI: 10.1016/j.celrep.2023.112104
  
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sciencedirect.com/science/article/pii/S2211124723001158
Jan 2023
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Drosophila transition fibers are essential for IFT-dependent ciliary elongation but not basal body docking and ciliary budding

1
1. scibot 21 Jan 2023
  
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  DOI: 10.1016/j.cub.2022.12.046
  
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sciencedirect.com/science/article/pii/S0960982222019832
Sep 2022
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Snail maintains the stem/progenitor state of skin epithelial cells and carcinomas through the autocrine effect of matricellular protein Mindin

1
1. scibot 21 Sep 2022
  
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  DOI: 10.1016/j.celrep.2022.111390
  
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sciencedirect.com/science/article/pii/S221112472201227X
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

CANCER-ASSOCIATED SF3B1 MUTATIONS CONFER A BRCA-LIKE CELLULAR PHENOTYPE AND SYNTHETIC LETHALITY TO PARP INHIBITORS

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  DOI: 10.1158/0008-5472.CAN-21-1843
  
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pubmed.ncbi.nlm.nih.gov/35027467/
Aug 2022
europepmc.org europepmc.org

Processing and Subcellular Localization of the Hepatitis E Virus Replicase: Identification of Candidate Viral Factories

1
1. scibot 08 Aug 2022
  
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  DOI: 10.3389/fmicb.2022.828636
  
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europepmc.org/article/MED/35283856
Jul 2022
www.nature.com www.nature.com

LRRK2 kinase activity regulates GCase level and enzymatic activity differently depending on cell type in Parkinson’s disease

1
1. scibot 27 Jul 2022
  
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  DOI: 10.1038/s41531-022-00354-3
  
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nature.com/articles/s41531-022-00354-3
Jun 2022
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Replication stress triggered by nucleotide pool imbalance drives DNA damage and cGAS-STING pathway activation in NAFLD

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1. scibot 30 Jun 2022
  
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  DOI: 10.1016/j.devcel.2022.06.003
  
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sciencedirect.com/science/article/pii/S1534580722004129
May 2022
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Loss-of-function variants in the schizophrenia risk gene SETD1A alter neuronal network activity in human neurons through the cAMP/PKA pathway

1
1. scibot 13 May 2022
  
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  DOI: 10.1016/j.celrep.2022.110790
  
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Long-range migration of centrioles to the apical surface of the olfactory epithelium

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Glial-secreted Netrins regulate Robo1/Rac1-Cdc42 signaling threshold levels during Drosophila asymmetric neural stem/progenitor cell division

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Evolutionary conservation of centriole rotational asymmetry in the human centrosome

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Processing and Subcellular Localization of the Hepatitis E Virus Replicase: Identification of Candidate Viral Factories

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Protocol to measure inter-centrosome distance in adherent cells using epifluorescence microscopy

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Compartmentalized control of Cdk1 drives mitotic spindle assembly

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Defects in Emerin-nucleoskeleton binding disrupt nuclear structure and promote breast cancer cell motility and metastasis

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FKBP51 Affects TNF-Related Apoptosis Inducing Ligand Response in Melanoma

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Ciliary and extraciliary Gpr161 pools repress hedgehog signaling in a tissue-specific manner

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Untitled document

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FBF1 deficiency promotes beiging and healthy expansion of white adipose tissue

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C8ORF37 Is Required for Photoreceptor Outer Segment Disc Morphogenesis by Maintaining Outer Segment Membrane Protein Homeostasis

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The antioxidant response favors Leishmania parasites survival, limits inflammation and reprograms the host cell metabolism

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  DOI: 10.1371/journal.ppat.1009422
  
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Rab34 GTPase mediates ciliary membrane formation in the intracellular ciliogenesis pathway

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Parental genome unification is highly error-prone in mammalian embryos

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RAB19 Directs Cortical Remodeling and Membrane Growth for Primary Ciliogenesis

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Centrosomal Localization of RXRα Promotes PLK1 Activation and Mitotic Progression and Constitutes a Tumor Vulnerability

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Transient Primary Cilia Mediate Robust Hedgehog Pathway-Dependent Cell Cycle Control

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Reductive TCA cycle metabolism fuels glutamine- and glucose-stimulated insulin secretion

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RNA demethylation by FTO stabilizes the FOXJ1 mRNA for proper motile ciliogenesis

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Mar 2021
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Parkin is an E3 ligase for the ubiquitin-like modifier FAT10, which inhibits Parkin activation and mitophagy

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Mauve/LYST limits fusion of lysosome-related organelles and promotes centrosomal recruitment of microtubule nucleating proteins

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Drosophila Tubulin-Specific Chaperone E Recruits Tubulin around Chromatin to Promote Mitotic Spindle Assembly

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Actionable Cytopathogenic Host Responses of Human Alveolar Type 2 Cells to SARS-CoV-2

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ncbi.nlm.nih.gov/pmc/articles/PMC7674017/
Nov 2020
onlinelibrary.wiley.com onlinelibrary.wiley.com

Distinct alpha‐Synuclein species induced by seeding are selectively cleared by the Lysosome or the Proteasome in neuronally differentiated SH‐SY5Y cells

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  DOI: 10.1111/jnc.15174
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.15174
Sep 2020
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Sperm Head-Tail Linkage Requires Restriction of Pericentriolar Material to the Proximal Centriole End

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dev.biologists.org dev.biologists.org

The FOXJ1 target Cfap206 is required for sperm motility, mucociliary clearance of the airways and brain development

1
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  anti-gamma-Tubulin (γ-TUB) Clone GTU-88
  
  DOI: 10.1242/dev.188052
  
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Differences in Mitotic Spindle Architecture in Mammalian Neural Stem Cells Influence Mitotic Accuracy during Brain Development

1
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Cell-Cycle Asynchrony Generates DNA Damage at Mitotic Entry in Polyploid Cells

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LMO2 Confers Synthetic Lethality to PARP Inhibition in DLBCL

1
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Oncogenic Mutations Rewire Signaling Pathways by Switching Protein Recruitment to Phosphotyrosine Sites

1
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  DOI: 10.1016/j.cell.2019.09.008
  
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The Golgi Outpost Protein TPPP Nucleates Microtubules and Is Critical for Myelination

1
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  DOI: 10.1016/j.cell.2019.08.025
  
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Untitled document

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  DOI: 10.1016/j.molcel.2018.12.016
  
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  DOI: 10.1016/j.devcel.2019.03.027
  
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Untitled document

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1. scibot 12 Jan 2020
  
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  DOI: 10.1016/j.devcel.2018.12.017
  
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Nov 2018
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Simultaneous use of erythropoietin and LFM‐A13 as a new therapeutic approach for colorectal cancer

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ncbi.nlm.nih.gov/pmc/articles/PMC5811618/
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Untitled document

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The Reissner Fiber in the Cerebrospinal Fluid Controls Morphogenesis of the Body Axis

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γ-TuRC Heterogeneity Revealed by Analysis of Mozart1

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BC RNA Mislocalization in the Fragile X Premutation

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Mechanical Forces Program the Orientation of Cell Division during Airway Tube Morphogenesis

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The Primate-Specific Gene TMEM14B Marks Outer Radial Glia Cells and Promotes Cortical Expansion and Folding

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Inter-dependent apical microtubule and actin dynamics orchestrate centrosome retention and neuronal delamination.

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Mutations in ARMC9, which Encodes a Basal Body Protein, Cause Joubert Syndrome in Humans and Ciliopathy Phenotypes in Zebrafish

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1. scibot 08 Nov 2017
  
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GCL and CUL3 Control the Switch between Cell Lineages by Mediating Localized Degradation of an RTK

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1. scibot 08 Nov 2017
  
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A Splice Variant of Centrosomin Converts Mitochondria to Microtubule-Organizing Centers

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1. scibot 08 Nov 2017
  
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Human biallelic MFN2 mutations induce mitochondrial dysfunction, upper body adipose hyperplasia, and suppression of leptin expression

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1. scibot 08 Nov 2017
  
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2. scibot 08 Nov 2017
  
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