66 Matching Annotations
  1. Last 7 days
  2. www.sciencedirect.com www.sciencedirect.com
    Inflammation switches the chemoattractant requirements for naive lymphocyte entry into lymph nodes
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    1. scibot 21 Dec 2024
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      DOI: 10.1016/j.cell.2024.11.031

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    sciencedirect.com/science/article/pii/S0092867424013473
  3. Sep 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TUMOR-INFILTRATING NOCICEPTOR NEURONS PROMOTE IMMUNOSUPPRESSION
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    1. scibot 18 Sep 2024
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      DOI: 10.1101/2024.08.23.609450

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    ncbi.nlm.nih.gov/pmc/articles/PMC11382997/
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    Intercellular nanotube-mediated mitochondrial transfer enhances T cell metabolic fitness and antitumor efficacy
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    1. scibot 17 Sep 2024
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      DOI: 10.1016/j.cell.2024.08.029

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    sciencedirect.com/science/article/pii/S0092867424009565
  6. Aug 2024
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    Epithelial organoid supports resident memory CD8 T cell differentiation
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    1. scibot 22 Aug 2024
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      DOI: 10.1016/j.celrep.2024.114621

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    sciencedirect.com/science/article/pii/S2211124724009719
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    Aerobic glycolysis but not GLS1-dependent glutamine metabolism is critical for anti-tumor immunity and response to checkpoint inhibition
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    1. scibot 22 Aug 2024
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      DOI: 10.1016/j.celrep.2024.114632

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    sciencedirect.com/science/article/pii/S2211124724009823
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    LAG-3 sustains TOX expression and regulates the CD94/NKG2-Qa-1b axis to govern exhausted CD8 T cell NK receptor expression and cytotoxicity
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    1. scibot 20 Aug 2024
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      DOI: 10.1016/j.cell.2024.07.018

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    sciencedirect.com/science/article/pii/S0092867424007785
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    LAG-3 and PD-1 synergize on CD8+ T cells to drive T cell exhaustion and hinder autocrine IFN-γ-dependent anti-tumor immunity
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    1. scibot 20 Aug 2024
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      DOI: 10.1016/j.cell.2024.07.016

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    sciencedirect.com/science/article/pii/S0092867424007761
  11. Jul 2024
  12. 52.53.155.43 52.53.155.43
    Lack of canonical thyroid hormone receptor α signaling changes regulatory T cell phenotype in female mice
    1
    1. scibot 25 Jul 2024
      AB_572017

      DOI: 10.1016/j.isci.2024.110547

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    52.53.155.43/ec8bf473a95e0f0a14821b5e61884b766010f004/1-s2.0-S2589004224017723-main-html.html
  13. May 2024
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    The CD8+ T cell tolerance checkpoint triggers a distinct differentiation state defined by protein translation defects
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    1. scibot 23 May 2024
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      DOI: 10.1016/j.immuni.2024.04.026

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    sciencedirect.com/science/article/pii/S1074761324002310
  15. Jan 2024
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    Clinical and molecular features of acquired resistance to immunotherapy in non-small cell lung cancer
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    1. scibot 12 Jan 2024
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      DOI: 10.1016/j.ccell.2023.12.013

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    sciencedirect.com/science/article/pii/S1535610823004415
  17. Dec 2023
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    Stat5 opposes the transcription factor Tox and rewires exhausted CD8+ T cells toward durable effector-like states during chronic antigen exposure
    1
    1. scibot 17 Dec 2023
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      DOI: 10.1016/j.immuni.2023.11.005

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    sciencedirect.com/science/article/pii/S1074761323004879
  19. Oct 2023
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    Upregulation of exosome secretion from tumor-associated macrophages plays a key role in the suppression of anti-tumor immunity
    1
    1. scibot 13 Oct 2023
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      DOI: 10.1016/j.celrep.2023.113224

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    sciencedirect.com/science/article/pii/S2211124723012366
  21. Aug 2023
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glucose Oxidation-Dependent Survival of Activated B Cells Provides a Putative Novel Therapeutic Target for Lupus Treatment
    1
    1. scibot 26 Aug 2023
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      DOI: 10.1016/j.isci.2023.107487

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    ncbi.nlm.nih.gov/pmc/articles/PMC10448027/
  23. Jun 2023
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    Coupled deglycosylation-ubiquitination cascade in regulating PD-1 degradation by MDM2
    1
    1. scibot 28 Jun 2023
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      DOI: 10.1016/j.celrep.2023.112693

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    sciencedirect.com/science/article/pii/S2211124723007040
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    The SWI/SNF chromatin remodeling complexes BAF and PBAF differentially regulate epigenetic transitions in exhausted CD8+ T cells
    1
    1. scibot 23 Jun 2023
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      DOI: 10.1016/j.immuni.2023.05.008

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    sciencedirect.com/science/article/pii/S107476132300225X
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    DNA hypomethylation silences anti-tumor immune genes in early prostate cancer and CTCs
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    1. scibot 21 Jun 2023
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      DOI: 10.1016/j.cell.2023.05.028

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    sciencedirect.com/science/article/pii/S0092867423005809
  27. Mar 2023
  28. europepmc.org europepmc.org
    Neutralizing IL-8 potentiates immune checkpoint blockade efficacy for glioma
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    1. scibot 25 Mar 2023
      RRID:AB_572017

      DOI: 10.1016/j.ccell.2023.03.004

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    europepmc.org/article/med/36963400
  29. Jan 2023
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    Bispecific PD1-IL2v and anti-PD-L1 break tumor immunity resistance by enhancing stem-like tumor-reactive CD8+ T cells and reprogramming macrophages
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    1. scibot 12 Jan 2023
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      DOI: 10.1016/j.immuni.2022.12.006

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    sciencedirect.com/science/article/pii/S1074761322006422
  31. Dec 2022
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    Mucosal exposure to non-tuberculous mycobacteria elicits B cell-mediated immunity against pulmonary tuberculosis
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    1. scibot 18 Dec 2022
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      DOI: 10.1016/j.celrep.2022.111783

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    sciencedirect.com/science/article/pii/S2211124722016710
  33. Nov 2022
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Delineating the transcriptional landscape and clonal diversity of virus-specific CD4+ T cells during chronic viral infection
    1
    1. scibot 04 Nov 2022
      RRID:AB_572017

      DOI: 10.7554/eLife.80079

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    ncbi.nlm.nih.gov/pmc/articles/PMC9629829/
  35. Oct 2022
  36. www.science.org www.science.org
    PD-1/PD-L1 blockade abrogates a dysfunctional innate-adaptive immune axis in critical β-coronavirus disease
    1
    1. scibot 25 Oct 2022
      RRID:AB_572017

      DOI: 10.1126/sciadv.abn6545

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    science.org/doi/10.1126/sciadv.abn6545
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PD-1/PD-L1 blockade abrogates a dysfunctional innate-adaptive immune axis in critical β-coronavirus disease
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    1. scibot 07 Oct 2022
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      DOI: 10.1126/sciadv.abn6545

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    ncbi.nlm.nih.gov/pmc/articles/PMC9491709/
  38. Sep 2022
  39. www.sciencedirect.com www.sciencedirect.com
    ATF3 and CH25H regulate effector trogocytosis and anti-tumor activities of endogenous and immunotherapeutic cytotoxic T lymphocytes
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    1. scibot 07 Sep 2022
      RRID:AB_572017

      DOI: 10.1016/j.cmet.2022.08.007

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    sciencedirect.com/science/article/pii/S1550413122003503
  40. Jul 2022
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    Interleukin-21, acting beyond the immunological synapse, independently controls T follicular helper and germinal center B cells
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    1. scibot 27 Jul 2022
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      DOI: 10.1016/j.immuni.2022.06.020

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    sciencedirect.com/science/article/pii/S107476132200293X
  42. Jun 2022
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    Genome-wide CRISPR screens of T cell exhaustion identify chromatin remodeling factors that limit T cell persistence
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    1. scibot 24 Jun 2022
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      DOI: 10.1016/j.ccell.2022.06.001

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    sciencedirect.com/science/article/pii/S1535610822002318
  44. Apr 2022
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    Autocrine and paracrine IL-2 signals collaborate to regulate distinct phases of CD8 T cell memory
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    1. scibot 14 Apr 2022
      RRID:AB_572017

      DOI: 10.1016/j.celrep.2022.110632

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    sciencedirect.com/science/article/pii/S2211124722003849
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    The interferon-stimulated gene RIPK1 regulates cancer cell intrinsic and extrinsic resistance to immune checkpoint blockade
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    1. scibot 13 Apr 2022
      RRID:AB_572017

      DOI: 10.1016/j.immuni.2022.03.007

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    sciencedirect.com/science/article/pii/S1074761322001303
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    Microbiota-dependent activation of the myeloid calcineurin-NFAT pathway inhibits B7H3- and B7H4-dependent anti-tumor immunity in colorectal cancer
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    1. scibot 01 Apr 2022
      RRID:AB_572017

      DOI: 10.1016/j.immuni.2022.03.008

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    sciencedirect.com/science/article/pii/S1074761322001315
  48. Mar 2022
  49. www.sciencedirect.com www.sciencedirect.com
    Tfh-cell-derived interleukin 21 sustains effector CD8+ T cell responses during chronic viral infection
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    1. scibot 02 Mar 2022
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      DOI: 10.1016/j.immuni.2022.01.018

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    sciencedirect.com/science/article/pii/S1074761322000474
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    Follicular T Cells Optimize the Germinal Center Response to SARS-CoV-2 Protein Vaccination in Mice
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      DOI: 10.1016/j.celrep.2022.110399

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    sciencedirect.com/science/article/pii/S2211124722001206
  51. Feb 2022
  52. www.sciencedirect.com www.sciencedirect.com
    ICAM-1-mediated adhesion is a prerequisite for exosome-induced T cell suppression
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    1. scibot 02 Feb 2022
      RRID:AB_572017

      DOI: 10.1016/j.devcel.2022.01.002

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    sciencedirect.com/science/article/pii/S1534580722000028
  53. Dec 2021
  54. www.sciencedirect.com www.sciencedirect.com
    Neoantigen-driven B cell and CD4 T follicular helper cell collaboration promotes anti-tumor CD8 T cell responses
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      DOI: 10.1016/j.cell.2021.11.007

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    sciencedirect.com/science/article/pii/S0092867421013222
  55. Nov 2021
  56. www.sciencedirect.com www.sciencedirect.com
    CXCL10 chemokine regulates heterogeneity of the CD8+ T cell response and viral set point during chronic infection
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      DOI: 10.1016/j.immuni.2021.11.002

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    sciencedirect.com/science/article/pii/S1074761321004933
  57. Sep 2021
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    A Cre-driven allele-conditioning line to interrogate CD4+ conventional T cells
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      DOI: 10.1016/j.immuni.2021.08.029

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    sciencedirect.com/science/article/pii/S1074761321003630
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    Antigen dominance hierarchies shape TCF1+ progenitor CD8 T cell phenotypes in tumors
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      DOI: 10.1016/j.cell.2021.08.020

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    sciencedirect.com/science/article/pii/S0092867421009946
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    PD-1+ Tcf1+ CD8+ T cells from established chronic infection can form memory while retaining a stableimprint of persistent antigen exposure
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      DOI: 10.1016/j.celrep.2021.109672

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    sciencedirect.com/science/article/pii/S2211124721011165
  61. Aug 2021
  62. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 08 Aug 2021
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      DOI: 10.1016/j.celrep.2018.10.042

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    sciencedirect.com/science/article/pii/S2211124718316310
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      DOI: 10.1016/j.celrep.2018.10.042

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    ncbi.nlm.nih.gov/pmc/articles/PMC6289055/
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    IRF4 Activity Is Required in Established Plasma Cells to Regulate Gene Transcription and Mitochondrial Homeostasis
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    1. scibot 01 Aug 2021
      RRID:AB_572017

      DOI: 10.1016/j.celrep.2019.10.097

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    sciencedirect.com/science/article/pii/S2211124719314305
  65. Jul 2021
  66. www.sciencedirect.com www.sciencedirect.com
    Checkpoint Blockade Immunotherapy Induces Dynamic Changes in PD-1−CD8+ Tumor-Infiltrating T Cells
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  67. elifesciences.org elifesciences.org
    Natural Tr1-like cells do not confer long-term tolerogenic memory
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    Transforming growth factor-β-regulated mTOR activity preserves cellular metabolism to maintain long-term T cell responses in chronic infection
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    Endogenous Glucocorticoid Signaling Regulates CD8+ T Cell Differentiation and Development of Dysfunction in the Tumor Microenvironment
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  77. Nov 2020
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    Developmental Relationships of Four Exhausted CD8+ T Cell Subsets Reveals Underlying Transcriptional and Epigenetic Landscape Control Mechanisms
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  86. Jan 2020
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    CD4+ T Cell Help Is Required for the Formation of a Cytolytic CD8+ T Cell Subset that Protects against Chronic Infection and Cancer
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    IL-12 Blocks Tfh Cell Differentiation during Salmonella Infection, thereby Contributing to Germinal Center Suppression
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    Opposing Functions of Interferon Coordinate Adaptive and Innate Immune Responses to Cancer Immune Checkpoint Blockade
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  93. Nov 2018
  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  97. Nov 2017
  98. www.sciencedirect.com www.sciencedirect.com
    Enhancing CD8+ T Cell Fatty Acid Catabolism within a Metabolically Challenging Tumor Microenvironment Increases the Efficacy of Melanoma Immunotherapy
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    Follicular Helper T Cells are Essential for the Elimination of Plasmodium Infection - ScienceDirect
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    Tumor Interferon Signaling Regulates a Multigenic Resistance Program to Immune Checkpoint Blockade
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