58 Matching Annotations
  1. May 2024
  2. www.sciencedirect.com www.sciencedirect.com
    The CD8+ T cell tolerance checkpoint triggers a distinct differentiation state defined by protein translation defects
    1
    1. scibot 23 May 2024
      RRID:AB_572017

      DOI: 10.1016/j.immuni.2024.04.026

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    sciencedirect.com/science/article/pii/S1074761324002310
  3. Jan 2024
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    Clinical and molecular features of acquired resistance to immunotherapy in non-small cell lung cancer
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    1. scibot 12 Jan 2024
      RRID:AB_572017

      DOI: 10.1016/j.ccell.2023.12.013

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    sciencedirect.com/science/article/pii/S1535610823004415
  5. Dec 2023
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    Stat5 opposes the transcription factor Tox and rewires exhausted CD8+ T cells toward durable effector-like states during chronic antigen exposure
    1
    1. scibot 17 Dec 2023
      RRID:AB_572017

      DOI: 10.1016/j.immuni.2023.11.005

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    sciencedirect.com/science/article/pii/S1074761323004879
  7. Oct 2023
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    Upregulation of exosome secretion from tumor-associated macrophages plays a key role in the suppression of anti-tumor immunity
    1
    1. scibot 13 Oct 2023
      RRID:AB_572017

      DOI: 10.1016/j.celrep.2023.113224

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    sciencedirect.com/science/article/pii/S2211124723012366
  9. Aug 2023
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glucose Oxidation-Dependent Survival of Activated B Cells Provides a Putative Novel Therapeutic Target for Lupus Treatment
    1
    1. scibot 26 Aug 2023
      RRID:AB_572017

      DOI: 10.1016/j.isci.2023.107487

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    ncbi.nlm.nih.gov/pmc/articles/PMC10448027/
  11. Jun 2023
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    Coupled deglycosylation-ubiquitination cascade in regulating PD-1 degradation by MDM2
    1
    1. scibot 28 Jun 2023
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      DOI: 10.1016/j.celrep.2023.112693

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    sciencedirect.com/science/article/pii/S2211124723007040
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    The SWI/SNF chromatin remodeling complexes BAF and PBAF differentially regulate epigenetic transitions in exhausted CD8+ T cells
    1
    1. scibot 23 Jun 2023
      RRID:AB_572017

      DOI: 10.1016/j.immuni.2023.05.008

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    sciencedirect.com/science/article/pii/S107476132300225X
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    DNA hypomethylation silences anti-tumor immune genes in early prostate cancer and CTCs
    1
    1. scibot 21 Jun 2023
      RRID:AB_572017

      DOI: 10.1016/j.cell.2023.05.028

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    sciencedirect.com/science/article/pii/S0092867423005809
  15. Mar 2023
  16. europepmc.org europepmc.org
    Neutralizing IL-8 potentiates immune checkpoint blockade efficacy for glioma
    1
    1. scibot 25 Mar 2023
      RRID:AB_572017

      DOI: 10.1016/j.ccell.2023.03.004

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    europepmc.org/article/med/36963400
  17. Jan 2023
  18. www.sciencedirect.com www.sciencedirect.com
    Bispecific PD1-IL2v and anti-PD-L1 break tumor immunity resistance by enhancing stem-like tumor-reactive CD8+ T cells and reprogramming macrophages
    1
    1. scibot 12 Jan 2023
      RRID:AB_572017

      DOI: 10.1016/j.immuni.2022.12.006

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    sciencedirect.com/science/article/pii/S1074761322006422
  19. Dec 2022
  20. www.sciencedirect.com www.sciencedirect.com
    Mucosal exposure to non-tuberculous mycobacteria elicits B cell-mediated immunity against pulmonary tuberculosis
    1
    1. scibot 18 Dec 2022
      RRID:AB_572017

      DOI: 10.1016/j.celrep.2022.111783

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    sciencedirect.com/science/article/pii/S2211124722016710
  21. Nov 2022
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Delineating the transcriptional landscape and clonal diversity of virus-specific CD4+ T cells during chronic viral infection
    1
    1. scibot 04 Nov 2022
      RRID:AB_572017

      DOI: 10.7554/eLife.80079

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    ncbi.nlm.nih.gov/pmc/articles/PMC9629829/
  23. Oct 2022
  24. www.science.org www.science.org
    PD-1/PD-L1 blockade abrogates a dysfunctional innate-adaptive immune axis in critical β-coronavirus disease
    1
    1. scibot 25 Oct 2022
      RRID:AB_572017

      DOI: 10.1126/sciadv.abn6545

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    science.org/doi/10.1126/sciadv.abn6545
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PD-1/PD-L1 blockade abrogates a dysfunctional innate-adaptive immune axis in critical β-coronavirus disease
    1
    1. scibot 07 Oct 2022
      RRID:AB_572017

      DOI: 10.1126/sciadv.abn6545

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    ncbi.nlm.nih.gov/pmc/articles/PMC9491709/
  26. Sep 2022
  27. www.sciencedirect.com www.sciencedirect.com
    ATF3 and CH25H regulate effector trogocytosis and anti-tumor activities of endogenous and immunotherapeutic cytotoxic T lymphocytes
    1
    1. scibot 07 Sep 2022
      RRID:AB_572017

      DOI: 10.1016/j.cmet.2022.08.007

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    sciencedirect.com/science/article/pii/S1550413122003503
  28. Jul 2022
  29. www.sciencedirect.com www.sciencedirect.com
    Interleukin-21, acting beyond the immunological synapse, independently controls T follicular helper and germinal center B cells
    1
    1. scibot 27 Jul 2022
      RRID:AB_572017

      DOI: 10.1016/j.immuni.2022.06.020

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    sciencedirect.com/science/article/pii/S107476132200293X
  30. Jun 2022
  31. www.sciencedirect.com www.sciencedirect.com
    Genome-wide CRISPR screens of T cell exhaustion identify chromatin remodeling factors that limit T cell persistence
    1
    1. scibot 24 Jun 2022
      RRID:AB_572017

      DOI: 10.1016/j.ccell.2022.06.001

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    sciencedirect.com/science/article/pii/S1535610822002318
  32. Apr 2022
  33. www.sciencedirect.com www.sciencedirect.com
    Autocrine and paracrine IL-2 signals collaborate to regulate distinct phases of CD8 T cell memory
    1
    1. scibot 14 Apr 2022
      RRID:AB_572017

      DOI: 10.1016/j.celrep.2022.110632

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    sciencedirect.com/science/article/pii/S2211124722003849
  34. www.sciencedirect.com www.sciencedirect.com
    The interferon-stimulated gene RIPK1 regulates cancer cell intrinsic and extrinsic resistance to immune checkpoint blockade
    1
    1. scibot 13 Apr 2022
      RRID:AB_572017

      DOI: 10.1016/j.immuni.2022.03.007

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    sciencedirect.com/science/article/pii/S1074761322001303
  35. www.sciencedirect.com www.sciencedirect.com
    Microbiota-dependent activation of the myeloid calcineurin-NFAT pathway inhibits B7H3- and B7H4-dependent anti-tumor immunity in colorectal cancer
    1
    1. scibot 01 Apr 2022
      RRID:AB_572017

      DOI: 10.1016/j.immuni.2022.03.008

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    sciencedirect.com/science/article/pii/S1074761322001315
  36. Mar 2022
  37. www.sciencedirect.com www.sciencedirect.com
    Tfh-cell-derived interleukin 21 sustains effector CD8+ T cell responses during chronic viral infection
    1
    1. scibot 02 Mar 2022
      RRID:AB_572017

      DOI: 10.1016/j.immuni.2022.01.018

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    sciencedirect.com/science/article/pii/S1074761322000474
  38. www.sciencedirect.com www.sciencedirect.com
    Follicular T Cells Optimize the Germinal Center Response to SARS-CoV-2 Protein Vaccination in Mice
    1
    1. scibot 02 Mar 2022
      RRID:AB_572017

      DOI: 10.1016/j.celrep.2022.110399

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    sciencedirect.com/science/article/pii/S2211124722001206
  39. Feb 2022
  40. www.sciencedirect.com www.sciencedirect.com
    ICAM-1-mediated adhesion is a prerequisite for exosome-induced T cell suppression
    1
    1. scibot 02 Feb 2022
      RRID:AB_572017

      DOI: 10.1016/j.devcel.2022.01.002

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    sciencedirect.com/science/article/pii/S1534580722000028
  41. Dec 2021
  42. www.sciencedirect.com www.sciencedirect.com
    Neoantigen-driven B cell and CD4 T follicular helper cell collaboration promotes anti-tumor CD8 T cell responses
    1
    1. scibot 01 Dec 2021
      RRID:AB_572017

      DOI: 10.1016/j.cell.2021.11.007

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    sciencedirect.com/science/article/pii/S0092867421013222
  43. Nov 2021
  44. www.sciencedirect.com www.sciencedirect.com
    CXCL10 chemokine regulates heterogeneity of the CD8+ T cell response and viral set point during chronic infection
    1
    1. scibot 30 Nov 2021
      RRID:AB_572017

      DOI: 10.1016/j.immuni.2021.11.002

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    sciencedirect.com/science/article/pii/S1074761321004933
  45. Sep 2021
  46. www.sciencedirect.com www.sciencedirect.com
    A Cre-driven allele-conditioning line to interrogate CD4+ conventional T cells
    1
    1. scibot 22 Sep 2021
      RRID:AB_572017

      DOI: 10.1016/j.immuni.2021.08.029

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    sciencedirect.com/science/article/pii/S1074761321003630
  47. www.sciencedirect.com www.sciencedirect.com
    Antigen dominance hierarchies shape TCF1+ progenitor CD8 T cell phenotypes in tumors
    1
    1. scibot 18 Sep 2021
      RRID:AB_572017

      DOI: 10.1016/j.cell.2021.08.020

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    sciencedirect.com/science/article/pii/S0092867421009946
  48. www.sciencedirect.com www.sciencedirect.com
    PD-1+ Tcf1+ CD8+ T cells from established chronic infection can form memory while retaining a stableimprint of persistent antigen exposure
    1
    1. scibot 08 Sep 2021
      RRID:AB_572017

      DOI: 10.1016/j.celrep.2021.109672

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    sciencedirect.com/science/article/pii/S2211124721011165
  49. Aug 2021
  50. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 08 Aug 2021
      RRID:AB_572017

      DOI: 10.1016/j.celrep.2018.10.042

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    sciencedirect.com/science/article/pii/S2211124718316310
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    1. scibot 04 Aug 2021
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      DOI: 10.1016/j.celrep.2018.10.042

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    ncbi.nlm.nih.gov/pmc/articles/PMC6289055/
  52. www.sciencedirect.com www.sciencedirect.com
    IRF4 Activity Is Required in Established Plasma Cells to Regulate Gene Transcription and Mitochondrial Homeostasis
    1
    1. scibot 01 Aug 2021
      RRID:AB_572017

      DOI: 10.1016/j.celrep.2019.10.097

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    sciencedirect.com/science/article/pii/S2211124719314305
  53. Jul 2021
  54. www.sciencedirect.com www.sciencedirect.com
    Checkpoint Blockade Immunotherapy Induces Dynamic Changes in PD-1−CD8+ Tumor-Infiltrating T Cells
    1
    1. scibot 31 Jul 2021
      AB_572017

      DOI: 10.1016/j.immuni.2018.11.014

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    sciencedirect.com/science/article/pii/S1074761318305223
  55. elifesciences.org elifesciences.org
    Natural Tr1-like cells do not confer long-term tolerogenic memory
    1
    1. scibot 30 Jul 2021
      Rat monoclonal PD1 (clone RMP1-30)

      DOI: 10.7554/eLife.44821

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    elifesciences.org/articles/44821
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      DOI: 10.1016/j.ebiom.2017.08.030

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    ncbi.nlm.nih.gov/pmc/articles/PMC5652023/
  57. www.sciencedirect.com www.sciencedirect.com
    Transforming growth factor-β-regulated mTOR activity preserves cellular metabolism to maintain long-term T cell responses in chronic infection
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    1. scibot 07 Jul 2021
      RRID:AB_572017

      DOI: 10.1016/j.immuni.2021.06.007

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    sciencedirect.com/science/article/pii/S107476132100251X
  58. May 2021
  59. www.sciencedirect.com www.sciencedirect.com
    Suppressive neutrophils require PIM1 for metabolic fitness and survival during chronic viral infection
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    1. scibot 26 May 2021
      RRID:AB_572017

      DOI: 10.1016/j.celrep.2021.109160

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    sciencedirect.com/science/article/pii/S2211124721005027
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    Endogenous Glucocorticoid Signaling Regulates CD8+ T Cell Differentiation and Development of Dysfunction in the Tumor Microenvironment
    1
    1. scibot 06 May 2021
      RRID:AB_572017

      DOI: 10.1016/j.immuni.2020.08.005

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    sciencedirect.com/science/article/pii/S1074761320303587
  61. Apr 2021
  62. www.sciencedirect.com www.sciencedirect.com
    TGFβ restricts expansion, survival, and function of T cells within the tuberculous granuloma
    1
    1. scibot 29 Apr 2021
      RRID:AB_572017

      DOI: 10.1016/j.chom.2021.02.005

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    sciencedirect.com/science/article/pii/S1931312821000846
  63. Feb 2021
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV-2 mRNA Vaccines Foster Potent Antigen-Specific Germinal Center Responses Associated with Neutralizing Antibody Generation
    1
    1. scibot 27 Feb 2021
      RRID:AB_572017

      DOI: 10.1016/j.immuni.2020.11.009

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    ncbi.nlm.nih.gov/pmc/articles/PMC7680029/
  65. Nov 2020
  66. www.sciencedirect.com www.sciencedirect.com
    Metabolic Reprogramming Induces Germinal Center B Cell Differentiation through Bcl6 Locus Remodeling
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    1. scibot 07 Nov 2020
      RRID:AB_572017

      DOI: 10.1016/j.celrep.2020.108333

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  67. Sep 2020
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    The PD-1 Pathway Regulates Development and Function of Memory CD8+ T Cells following Respiratory Viral Infection
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    Developmental Relationships of Four Exhausted CD8+ T Cell Subsets Reveals Underlying Transcriptional and Epigenetic Landscape Control Mechanisms
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  74. Jan 2020
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    CD4+ T Cell Help Is Required for the Formation of a Cytolytic CD8+ T Cell Subset that Protects against Chronic Infection and Cancer
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    IL-12 Blocks Tfh Cell Differentiation during Salmonella Infection, thereby Contributing to Germinal Center Suppression
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    Opposing Functions of Interferon Coordinate Adaptive and Innate Immune Responses to Cancer Immune Checkpoint Blockade
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  85. Nov 2017
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    Enhancing CD8+ T Cell Fatty Acid Catabolism within a Metabolically Challenging Tumor Microenvironment Increases the Efficacy of Melanoma Immunotherapy
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    Follicular Helper T Cells are Essential for the Elimination of Plasmodium Infection - ScienceDirect
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    Tumor Interferon Signaling Regulates a Multigenic Resistance Program to Immune Checkpoint Blockade
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