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Dynamicity of Topoisomerase 1 binding at super-enhancers regulates TLR-responsive gene expression program in macrophages

1
1. scibot 29 Jun 2026
  
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  RRID:AB_577241
  
  DOI: 10.1016/j.celrep.2026.117604
  
  Resource: (Bethyl Cat# A300-793A, RRID:AB_577241)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S2211124726006820
Sep 2025
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Extrachromosomal DNA associates with nuclear condensates and reorganizes chromatin structures to enhance oncogenic transcription

1
1. scibot 19 Sep 2025
  
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  RRID:AB_577241
  
  DOI: 10.1016/j.ccell.2025.08.008
  
  Resource: (Bethyl Cat# A300-793A, RRID:AB_577241)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S1535610825003654
May 2025
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Mediator regulates transcriptional termination through crosstalk with pre-mRNA 3′ end processing factors

1
1. scibot 29 May 2025
  
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  RRID:AB_577241
  
  DOI: 10.1016/j.molcel.2025.05.006
  
  Resource: (Bethyl Cat# A300-793A, RRID:AB_577241)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S1097276525004113
Dec 2024
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Proteolethargy is a pathogenic mechanism in chronic disease

1
1. scibot 02 Dec 2024
  
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  RRID:AB_577241
  
  DOI: 10.1016/j.cell.2024.10.051
  
  Resource: (Bethyl Cat# A300-793A, RRID:AB_577241)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S0092867424012741
May 2024
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The Mediator Med23 controls a transcriptional switch for muscle stem cell proliferation and differentiation in muscle regeneration

1
1. scibot 01 May 2024
  
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  RRID:AB_577241
  
  DOI: 10.1016/j.celrep.2024.114177
  
  Resource: (Bethyl Cat# A300-793A, RRID:AB_577241)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S2211124724005059
Apr 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

STAT3 couples activated tyrosine kinase signaling to the oncogenic core transcriptional regulatory circuitry of anaplastic large cell lymphoma

1
1. scibot 03 Apr 2024
  
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  RRID:AB_577241
  
  DOI: 10.1016/j.xcrm.2024.101472
  
  Resource: (Bethyl Cat# A300-793A, RRID:AB_577241)
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10983107/
Mar 2024
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Acetyl-CoA production by Mediator-bound 2-ketoacid dehydrogenases boosts de novo histone acetylation and is regulated by nitric oxide

1
1. scibot 08 Mar 2024
  
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  BethylA300-793A; RRID:AB_577241
  
  DOI: 10.1016/j.molcel.2023.12.033
  
  Resource: (Bethyl Cat# A300-793A, RRID:AB_577241)
  
  Curator: @abever99
  
  SciCrunch record: RRID:AB_577241
  
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sciencedirect.com/science/article/pii/S1097276523010791
Aug 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Differentiation block in acute myeloid leukemia regulated by intronic sequences of FTO

1
1. scibot 04 Aug 2023
  
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  RRID:AB_577241
  
  DOI: 10.1016/j.isci.2023.107319
  
  Resource: (Bethyl Cat# A300-793A, RRID:AB_577241)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_577241
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10393733/
Mar 2023
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Leaked genomic and mitochondrial DNA contribute to the host response to noroviruses in a STING-dependent manner

1
1. scibot 28 Mar 2023
  
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  RRID:AB_577241
  
  DOI: 10.1016/j.celrep.2023.112179
  
  Resource: (Bethyl Cat# A300-793A, RRID:AB_577241)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_577241
  
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  RRID:AB_577241
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sciencedirect.com/science/article/pii/S2211124723001900
Jan 2023
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Functional partitioning of transcriptional regulators by patterned charge blocks

1
1. scibot 05 Jan 2023
  
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  AB_577241
  
  DOI: 10.1016/j.cell.2022.12.013
  
  Resource: (Bethyl Cat# A300-793A, RRID:AB_577241)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_577241
  
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sciencedirect.com/science/article/pii/S0092867422015264
Nov 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

PPARγ lipodystrophy mutants reveal intermolecular interactions required for enhancer activation

1
1. scibot 22 Nov 2022
  
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  RRID:AB_577241
  
  DOI: 10.1038/s41467-022-34766-9
  
  Resource: (Bethyl Cat# A300-793A, RRID:AB_577241)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_577241
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9675755/
Aug 2022
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Pancreas agenesis mutations disrupt a lead enhancer controlling a developmental enhancer cluster

1
1. scibot 23 Aug 2022
  
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  RRID:AB_577241
  
  DOI: 10.1016/j.devcel.2022.07.014
  
  Resource: (Bethyl Cat# A300-793A, RRID:AB_577241)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_577241
  
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  RRID:AB_577241
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sciencedirect.com/science/article/pii/S1534580722005317
May 2022
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XIST loss impairs mammary stem cell differentiation and increases tumorigenicity through Mediator hyperactivation

1
1. scibot 25 May 2022
  
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  RRID:AB_577241
  
  DOI: 10.1016/j.cell.2022.04.034
  
  Resource: (Bethyl Cat# A300-793A, RRID:AB_577241)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_577241
  
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  RRID:AB_577241
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sciencedirect.com/science/article/pii/S0092867422005323
Feb 2022
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CASCADE: high-throughput characterization of regulatory complex binding altered by non-coding variants

2
1. scibot 11 Feb 2022
  
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  RRID:AB_577241
  
  DOI: 10.1016/j.xgen.2022.100098
  
  Resource: (Bethyl Cat# A300-793A, RRID:AB_577241)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_577241
  
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  RRID:AB_577241
2. scibot 11 Feb 2022
  
  in Public
  
  RRID:AB_577241
  
  DOI: 10.1016/j.xgen.2022.100098
  
  Resource: (Bethyl Cat# A300-793A, RRID:AB_577241)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_577241
  
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  RRID:AB_577241
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sciencedirect.com/science/article/pii/S2666979X22000155
Nov 2021
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An expansion of the non-coding genome and its regulatory potential underlies vertebrate neuronal diversity

1
1. scibot 02 Nov 2021
  
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  RRID:AB_577241
  
  DOI: 10.1016/j.neuron.2021.10.014
  
  Resource: (Bethyl Cat# A300-793A, RRID:AB_577241)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_577241
  
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sciencedirect.com/science/article/pii/S0896627321007820
Oct 2021
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Nuclear-localized human respiratory syncytial virus NS1 protein modulates host gene transcription

1
1. scibot 13 Oct 2021
  
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  RRID:AB_577241
  
  DOI: 10.1016/j.celrep.2021.109803
  
  Resource: (Bethyl Cat# A300-793A, RRID:AB_577241)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_577241
  
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  RRID:AB_577241
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sciencedirect.com/science/article/pii/S2211124721012638
Jul 2021
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The Mediator subunit MED20 organizes the early adipogenic complex to promote development of adipose tissues and diet-induced obesity

1
1. scibot 09 Jul 2021
  
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  A300-793A-10
  
  DOI: 10.1016/j.celrep.2021.109314
  
  Resource: (Bethyl Cat# A300-793A, RRID:AB_577241)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_577241
  
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  RRIDCUR:Missing RRID:AB_577241
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sciencedirect.com/science/article/pii/S2211124721006902
May 2021
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Unique Immune Cell Coactivators Specify Locus Control Region Function and Cell Stage

1
1. scibot 08 May 2021
  
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  RRID:AB_577241
  
  DOI: 10.1016/j.molcel.2020.10.036
  
  Resource: (Bethyl Cat# A300-793A, RRID:AB_577241)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_577241
  
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  RRID:AB_577241
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sciencedirect.com/science/article/pii/S1097276520307437
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Pancreatic Cancer Cells Require the Transcription Factor MYRF to Maintain ER Homeostasis

1
1. scibot 05 May 2021
  
  in Public
  
  RRID:AB_577241
  
  DOI: 10.1016/j.devcel.2020.09.011
  
  Resource: (Bethyl Cat# A300-793A, RRID:AB_577241)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_577241
  
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  RRID:AB_577241
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sciencedirect.com/science/article/pii/S1534580720307139
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CD276 expression enables squamous cell carcinoma stem cells to evade immune surveillance

1
1. scibot 04 May 2021
  
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  RRID:AB_577241
  
  DOI: 10.1016/j.stem.2021.04.011
  
  Resource: (Bethyl Cat# A300-793A, RRID:AB_577241)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_577241
  
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  RRID:AB_577241 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1934590921001685
Feb 2021
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The corepressors GPS2 and SMRT control enhancer and silencer remodeling via eRNA transcription during inflammatory activation of macrophages

1
1. scibot 25 Feb 2021
  
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  RRID:AB_577241
  
  DOI: 10.1016/j.molcel.2020.12.040
  
  Resource: (Bethyl Cat# A300-793A, RRID:AB_577241)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_577241
  
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  RRIDCUR:Validated RRID:AB_577241
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RRIDCUR:Validated

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sciencedirect.com/science/article/pii/S1097276520309618
Jan 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

1
1. scibot 12 Jan 2020
  
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  RRID:AB_577241
  
  DOI: 10.7554/eLife.40364
  
  Resource: (Bethyl Cat# A300-793A, RRID:AB_577241)
  
  Curator: @evieth
  
  SciCrunch record: RRID:AB_577241
  
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  RRID:AB_577241 RRIDCUR:Validated
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ncbi.nlm.nih.gov/pmc/articles/PMC6344081/
Nov 2018
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

1
1. scibot 05 Nov 2018
  
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  RRID:AB_577241
  
  Resource used:
  
  (Bethyl Cat# A300-793A, RRID:AB_577241)
  
  SciCrunch record: RRID:AB_577241
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:AB_577241
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ncbi.nlm.nih.gov/pmc/articles/PMC6039721/
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The Nucleosome Remodeling and Deacetylation Complex Modulates Chromatin Structure at Sites of Active Transcription to Fine-Tune Gene Expression

1
1. scibot 05 Nov 2018
  
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  RRID:AB_577241
  
  Curator: @evieth
  
  Resource used:
  
  (Bethyl Cat# A300-793A, RRID:AB_577241)
  
  SciCrunch record: RRID:AB_577241
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:AB_577241 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1097276518304453
Nov 2017
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ERK-Induced Activation of TCF Family of SRF Cofactors Initiates a Chromatin Modification Cascade Associated with Transcription

1
1. scibot 08 Nov 2017
  
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  A300793A
  
  Curator: @Jmenke
  
  Resource used:
  
  (Bethyl Cat# A300-793A, RRID:AB_577241)
  
  SciCrunch record: RRID:AB_577241
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:AB_577241 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S1097276517300977
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LRP8-Reelin-Regulated Neuronal Enhancer Signature Underlying Learning and Memory Formation

1
1. scibot 08 Nov 2017
  
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  AB_577241
  
  Curator: @gabimpine
  
  Resource used:
  
  (Bethyl Cat# A300-793A, RRID:AB_577241)
  
  SciCrunch record: RRID:AB_577241
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:AB_577241
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sciencedirect.com/science/article/pii/S0896627315002573