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A Pleiotropic and Functionally Divergent RAC3 Variant Disrupts Neurodevelopment and Impacts Organogenesis

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1. scibot 21 Oct 2025
  
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  DOI: 10.3390/cells14191499
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12523998/
Aug 2025
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Interleukin-4 induces CD11c+ microglia leading to amelioration of neuropathic pain in mice

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1. scibot 06 Aug 2025
  
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  DOI: 10.7554/eLife.105087
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12316456/
May 2025
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Neofunctionalization of VAMP7 opened up a plant-unique vacuolar transport pathway

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1. scibot 17 May 2025
  
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  DOI: 10.1016/j.cub.2025.04.062
  
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sciencedirect.com/science/article/pii/S0960982225005597
Mar 2025
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Amyloid-β-Driven Synaptic Deficits Are Mediated by Synaptic Removal of GluA3-Containing AMPA Receptors

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1. scibot 01 Mar 2025
  
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  DOI: 10.1523/JNEUROSCI.0393-24.2024
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11867010/
Feb 2025
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A p.N92K variant of the GTPase RAC3 disrupts cortical neuron migration and axon elongation

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1. scibot 27 Feb 2025
  
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  DOI: 10.1016/j.jbc.2025.108346
  
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sciencedirect.com/science/article/pii/S0021925825001954
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Keratinocyte-driven dermal collagen formation in the axolotl skin

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1. scibot 25 Feb 2025
  
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  DOI: 10.1038/s41467-025-57055-7
  
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nature.com/articles/s41467-025-57055-7
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SENP1 decreases RNF168 phase separation to promote DNA damage repair and drug resistance in colon cancer

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1. scibot 13 Feb 2025
  
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  DOI: 10.1158/0008-5472.CAN-22-4017
  
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aacrjournals.org/cancerres/article/83/17/2908/728579/SENP1-Decreases-RNF168-Phase-Separation-to-Promote
Jan 2025
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Amygdalo-cortical dialogue underlies memory enhancement by emotional association

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1. scibot 30 Jan 2025
  
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  DOI: 10.1016/j.neuron.2025.01.001
  
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sciencedirect.com/science/article/pii/S0896627325000054
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1-s2.0-S2589004224029377-main-html.html

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1. scibot 03 Jan 2025
  
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  DOI: 10.1016/j.isci.2024.111710
  
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52.53.155.43/a4a95d0f48e4f5d6b60e2092f92dc9e622c6d3c5/1-s2.0-S2589004224029377-main-html.html
Dec 2024
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The p.R66W Variant in RAC3 Causes Severe Fetopathy Through Variant-Specific Mechanisms

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1. scibot 22 Dec 2024
  
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  DOI: 10.3390/cells13232032
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11640247/
Nov 2024
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Kinesin-1 mediates proper ER folding of the CaV1.2 channel and maintains mouse glucose homeostasis

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1. scibot 14 Nov 2024
  
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  DOI: 10.1038/s44319-024-00246-y
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11549326/
Sep 2024
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Pathophysiological significance of the p.E31G variant in RAC1 responsible for a neurodevelopmental disorder with microcephaly

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1. scibot 26 Sep 2024
  
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  DOI: 10.1016/j.bbadis.2024.167520
  
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sciencedirect.com/science/article/pii/S0925443924005143
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CD34 distribution in C-fiber low threshold mechanoreceptors in the mouse dorsal root ganglion and spinal cord

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1. scibot 10 Sep 2024
  
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  DOI: 10.1016/j.brainres.2024.149227
  
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sciencedirect.com/science/article/pii/S0006899324004815
Aug 2024
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Dynamin 1xA interacts with Endophilin A1 via its spliced long C-terminus for ultrafast endocytosis

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1. scibot 22 Aug 2024
  
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  DOI: 10.1038/s44318-024-00145-x
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11329700/
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Reelin receptors ApoER2 and VLDLR are expressed in distinct spatiotemporal patterns in developing mouse cerebral cortex

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1. scibot 02 Aug 2024
  
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  AB_591819
  
  DOI: 10.1002/cne.23691
  
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onlinelibrary.wiley.com/doi/10.1002/cne.23691/full
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Vesicular stomatitis virus enables gene transfer and transsynaptic tracing in a wide range of organisms

2
1. scibot 02 Aug 2024
  
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  AB_591819
  
  DOI: 10.1002/cne.23761
  
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2. scibot 02 Aug 2024
  
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  AB_591819
  
  DOI: 10.1002/cne.23761
  
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onlinelibrary.wiley.com/doi/10.1002/cne.23761/full
Jul 2024
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A human commensal-pathogenic fungus suppresses host immunity via targeting TBK1

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1. scibot 31 Jul 2024
  
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  DOI: 10.1016/j.chom.2024.07.003
  
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sciencedirect.com/science/article/pii/S1931312824002622
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Translocational attenuation mediated by the PERK-SRP14 axis is a protective mechanism of unfolded protein response

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1. scibot 23 Jul 2024
  
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  DOI: 10.1016/j.celrep.2024.114402
  
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sciencedirect.com/science/article/pii/S2211124724007307
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Miga-mediated endoplasmic reticulum–mitochondria contact sites regulate neuronal homeostasis

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1. scibot 21 Jul 2024
  
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  DOI: 10.7554/eLife.56584
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7556861/
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Kinesin-1 mediates proper ER folding of the CaV1.2 channel and maintains mouse glucose homeostasis

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1. scibot 04 Jul 2024
  
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  DOI: 10.1101/2024.06.24.600327
  
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biorxiv.org/content/10.1101/2024.06.24.600327v1
Mar 2024
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All-optical presynaptic plasticity induction by photoactivated adenylyl cyclase targeted to axon terminals

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1. scibot 27 Mar 2024
  
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  DOI: 10.1016/j.crmeth.2024.100740
  
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sciencedirect.com/science/article/pii/S2667237524000651
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Generation of a common marmoset embryonic stem cell line CMES40-OC harboring a POU5F1 (OCT4)-2A-mCerulean3 knock-in reporter allele

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1. scibot 20 Mar 2024
  
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sciencedirect.com/science/article/pii/S1873506121001549
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In vivo CRISPR screening directly targeting testicular cells

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1. scibot 06 Mar 2024
  
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  DOI: 10.1016/j.xgen.2024.100510
  
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sciencedirect.com/science/article/pii/S2666979X24000375
Oct 2023
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Very-long-chain fatty acids are crucial to neuronal polarity by providing sphingolipids to lipid rafts

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1. scibot 13 Oct 2023
  
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  DOI: 10.1016/j.celrep.2023.113195
  
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sciencedirect.com/science/article/pii/S221112472301207X
Sep 2023
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Thalamocortical control of cell-type specificity drives circuits for processing whisker-related information in mouse barrel cortex

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1. scibot 29 Sep 2023
  
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  DOI: 10.1038/s41467-023-41749-x
  
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nature.com/articles/s41467-023-41749-x
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Nutrient-driven dedifferentiation of enteroendocrine cells promotes adaptive intestinal growth in Drosophila

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1. scibot 16 Sep 2023
  
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  DOI: 10.1016/j.devcel.2023.08.022
  
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sciencedirect.com/science/article/abs/pii/S1534580723004379
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CD44 correlates with longevity and enhances basal ATF6 activity and ER stress resistance

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1. scibot 16 Sep 2023
  
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  DOI: 10.1016/j.celrep.2023.113130
  
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sciencedirect.com/science/article/pii/S2211124723011427
Aug 2023
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Overexpression of NT-3 in the hippocampus suppresses the early phase of the adult neurogenic process

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1. scibot 12 Aug 2023
  
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  DOI: 10.3389/fnins.2023.1178555
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10413268/
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can-22-4017-html.html

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  DOI: 10.1158/0008-5472.can-22-4017
  
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  DOI: 10.1158/0008-5472.CAN-22-4017
  
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52.53.155.43/9095f2133470165b212e6a97c53f24a603903e15/can-22-4017 (1)-html.html
Jun 2023
www.embopress.org www.embopress.org

Phosphorylation of phase-separated p62 bodies by ULK1 activates a redox-independent stress response

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1. scibot 15 Jun 2023
  
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  DOI: 10.15252/embj.2022113349
  
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embopress.org/doi/10.15252/embj.2022113349
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Centromere/kinetochore is assembled through CENP-C oligomerization

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1. scibot 09 Jun 2023
  
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  DOI: 10.1016/j.molcel.2023.05.023
  
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sciencedirect.com/science/article/pii/S1097276523003799
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Differential toxicity and localization of arginine-rich C9ORF72 dipeptide repeat proteins depend on de-clustering of positive charges.

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1. scibot 08 Jun 2023
  
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  DOI: 10.1016/j.isci.2023.106957
  
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sciencedirect.com/science/article/pii/S2589004223010349
May 2023
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Integrated proteomics identifies p62-dependent selective autophagy of the supramolecular vault complex

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1. scibot 17 May 2023
  
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  DOI: 10.1016/j.devcel.2023.04.015
  
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sciencedirect.com/science/article/pii/S1534580723001910
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Variant-specific changes in RAC3 function disrupt corticogenesis in neurodevelopmental phenotypes

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1. scibot 05 May 2023
  
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  RRID:AB_591819
  
  DOI: 10.1093/brain/awac106
  
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academic.oup.com/brain/advance-article/doi/10.1093/brain/awac106/6628315
Apr 2023
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Bone marrow-derived fibroblast migration via periostin causes irreversible arthrogenic contracture after joint immobilization

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  RRID:AB_591819
  
  DOI: 10.1096/fj.202201598R
  
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faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202201598R
Mar 2023
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Monitoring autophagic flux in vivo revealed its physiological response and significance of heterogeneity in pancreatic beta cells

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  DOI: 10.1016/j.chembiol.2023.03.001
  
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Interaction between PI3K and the VDAC2 channel tethers Ras-PI3K-positive endosomes to mitochondria and promotes endosome maturation

1
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  DOI: 10.1016/j.celrep.2023.112229
  
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sciencedirect.com/science/article/pii/S2211124723002401
Jan 2023
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Hepatitis B Virus Utilizes a Retrograde Trafficking Route via the Trans-Golgi Network to Avoid Lysosomal Degradation

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  DOI: 10.1016/j.jcmgh.2022.10.008
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9868690/
Nov 2022
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Brain injury triggers cell-type-specific and time-dependent endoplasmic reticulum stress responses

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  DOI: 10.1002/glia.24303
  
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onlinelibrary.wiley.com/doi/10.1002/glia.24303
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Subsynaptic mobility of presynaptic mGluR types is differentially regulated by intra- and extracellular interactions

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  DOI: 10.1091/mbc.E21-10-0484
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9635276/
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ER-mitochondrial contact protein Miga regulates autophagy through Atg14 and Uvrag

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  RRID:AB_591819
  
  DOI: 10.1016/j.celrep.2022.111583
  
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Multiphase coalescence mediates Hippo pathway activation

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  RRID:AB_591819
  
  DOI: 10.1016/j.cell.2022.09.036
  
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sciencedirect.com/science/article/pii/S0092867422012557
Sep 2022
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Nanobody-based RFP-dependent Cre recombinase for selective anterograde tracing in RFP-expressing transgenic animals

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  RRID:AB_591819
  
  DOI: 10.1038/s42003-022-03944-2
  
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nature.com/articles/s42003-022-03944-2
Aug 2022
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Impaired disassembly of the axon initial segment restricts mitochondrial entry into damaged axons

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  DOI: 10.15252/embj.2021110486
  
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embopress.org/doi/10.15252/embj.2021110486
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Duplex Labeling and Manipulation of Neuronal Proteins Using Sequential CRISPR/Cas9 Gene Editing

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  DOI: 10.1523/ENEURO.0056-22.2022
  
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eneuro.org/content/9/4/ENEURO.0056-22.2022
Jul 2022
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A guiding role of the Arabidopsis circadian clock in cell differentiation revealed by time-series single-cell RNA sequencing

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Dynamin is primed at endocytic sites for ultrafast endocytosis

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  RRID:AB_591819
  
  DOI: 10.1016/j.neuron.2022.06.010
  
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Recruitment of tetraspanin TSP-15 to epidermal wounds promotes plasma membrane repair in C. elegans

2
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  RRID:AB_591819
  
  DOI: 10.1016/j.devcel.2022.06.004
  
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sciencedirect.com/science/article/pii/S1534580722004130
Jun 2022
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Lattice-patterned collagen fibers and their dynamics in axolotl skin regeneration

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  DOI: 10.1016/j.isci.2022.104524
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9213773/
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Gain-of-function p.F28S variant in RAC3 disrupts neuronal differentiation, migration and axonogenesis during cortical development, leading to neurodevelopmental disorder

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  DOI: 10.1136/jmedgenet-2022-108483
  
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jmg.bmj.com/content/early/2022/05/24/jmedgenet-2022-108483
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Motor Nerve Arborization Requires Proteolytic Domain of Damage-Induced Neuronal Endopeptidase (DINE) during Development

1
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  DOI: 10.1523/JNEUROSCI.3811-15.2016
  
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jneurosci.org/content/36/17/4744
Apr 2022
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C-terminal deletion-induced condensation sequesters AID from IgH targets in immunodeficiency

1
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  DOI: 10.15252/embj.2021109324
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9156971/
Mar 2022
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Parcellation of the murine cortical hindlimb area is demonstrated by its subcortical connectivity and cytoarchitecture

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  DOI: 10.1002/cne.25313
  
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onlinelibrary.wiley.com/doi/10.1002/cne.25313
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The PTN-PTPRZ signal activates the AFAP1L2-dependent PI3K-AKT pathway for oligodendrocyte differentiation: Targeted inactivation of PTPRZ activity in mice

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  RRID:AB_2313843
  
  DOI: 10.1002/glia.23583
  
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onlinelibrary.wiley.com/doi/10.1002/glia.23583
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Xeno-free culture for generation of forebrain oligodendrocyte precursor cells from human pluripotent stem cells

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  DOI: 10.1002/jnr.24413
  
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onlinelibrary.wiley.com/doi/10.1002/jnr.24413
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A coordinate-based co-localization index to quantify and visualize spatial associations in single-molecule localization microscopy

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  DOI: 10.1038/s41598-022-08746-4
  
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nature.com/articles/s41598-022-08746-4
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Cell-autonomous control of intracellular temperature by unsaturation of phospholipid acyl chains

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  MBL, #598
  
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Impaired Function of PLEKHG2, a Rho-Guanine Nucleotide-Exchange Factor, Disrupts Corticogenesis in Neurodevelopmental Phenotypes

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ncbi.nlm.nih.gov/pmc/articles/PMC8870177/
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Activity-dependent PI4P synthesis by PI4KIIIα regulates long-term synaptic potentiation

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sciencedirect.com/science/article/pii/S2211124722001796
Feb 2022
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Dynamics and nanoscale organization of the postsynaptic endocytic zone at excitatory synapses

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  RRID:AB_591819
  
  DOI: 10.7554/eLife.74387
  
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Gfap transgenic medaka as a novel reporter line for neural stem cells

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  DOI: 10.1016/j.gene.2022.146213
  
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Jan 2022
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Metastasis enhancer PGRMC1 boosts store-operated Ca2+ entry by uncoiling Ca2+ sensor STIM1 for focal adhesion turnover and actomyosin formation

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  DOI: 10.1016/j.celrep.2021.110281
  
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sciencedirect.com/science/article/pii/S2211124721017964
Nov 2021
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Redox-sensitive CDC-42 clustering promotes wound closure in C. elegans

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Lemur tail kinase 1 (LMTK1) regulates the endosomal localization of β-secretase BACE1

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  DOI: 10.1093/jb/mvab094
  
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academic.oup.com/jb/advance-article/doi/10.1093/jb/mvab094/6369789
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Distributed sensory coding by cerebellar complex spikes in units of cortical segments

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  DOI: 10.1016/j.celrep.2021.109966
  
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sciencedirect.com/science/article/pii/S2211124721014455
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GEM-IL: A highly responsive fluorescent lactate indicator

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  DOI: 10.1016/j.crmeth.2021.100092
  
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sciencedirect.com/science/article/pii/S2667237521001478
Sep 2021
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Regulation of lipid homeostasis by the TBC protein dTBC1D22 via modulation of the small GTPase Rab40 to facilitate lipophagy

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  DOI: 10.1016/j.celrep.2021.109541
  
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sciencedirect.com/science/article/pii/S221112472100975X
Aug 2021
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Cdc42 is required for male germline niche development in mice

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  DOI: 10.1016/j.celrep.2021.109550
  
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Untitled document

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  DOI: 10.1002/cne.24213
  
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Enhanced Axonal Extension of Subcortical Projection Neurons Isolated from Murine Embryonic Cortex using Neuropilin-1

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Enhanced Axonal Extension of Subcortical Projection Neurons Isolated from Murine Embryonic Cortex using Neuropilin-1

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Differential innervation within a transverse plane of spinal gray matter by sensorimotor cortices, with special reference to the somatosensory cortices

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Pathogenic <i>FAM83G</i> palmoplantar keratoderma mutations inhibit the PAWS1:CK1α association and attenuate Wnt signalling.

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Pro-inflammatory Aorta-Associated Macrophages Are Involved in Embryonic Development of Hematopoietic Stem Cells

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Dynamic Palmitoylation Targets MAP6 to the Axon to Promote Microtubule Stabilization during Neuronal Polarization

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Transient oxytocin signaling primes the development and function of excitatory hippocampal neurons

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Molecular cell identities in the mediodorsal thalamus of infant mice and marmoset

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WDR47 protects neuronal microtubule minus ends from katanin-mediated severing

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Ultracentrifugal separation, characterization, and functional study of extracellular vesicles derived from serum-free cell culture

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Airway basal stem cells reutilize the embryonic proliferation regulator, Tgfβ-Id2 axis, for tissue regeneration

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Extreme deformability of insect cell membranes is governed by phospholipid scrambling

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Dynamic subcellular localization and transcription activity of the SRF cofactor MKL2 in the striatum are regulated by MAPK

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Filopodium-derived vesicles produced by MIM enhance the migration of recipient cells

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A Division of Labor in the Recruitment and Topological Organization of a Bacterial Morphogenic Complex

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Visualizing and Modulating Mitophagy for Therapeutic Studies of Neurodegeneration

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Fast, cell-resolution, contiguous-wide two-photon imaging to reveal functional network architectures across multi-modal cortical areas

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Neuropathophysiological significance of the c.1449T>C/p.(Tyr64Cys) mutation in the CDC42 gene responsible for Takenouchi-Kosaki syndrome

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sciencedirect.com/science/article/pii/S0006291X2031322X
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Generation of a common marmoset embryonic stem cell line CMES40-OC harboring a POU5F1 (OCT4)-2A-mCerulean3 knock-in reporter allele

1
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Homeostatic Regulation of ROS-Triggered Hippo-Yki Pathway via Autophagic Clearance of Ref(2)P/p62 in the Drosophila Intestine

1
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Feb 2021
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A discrete subtype of neural progenitor crucial for cortical folding in the gyrencephalic mammalian brain

1
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  DOI: 10.7554/eLife.54873
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7173966/
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In vivo regeneration of neo-nephrons in rodents by renal progenitor cell transplantation

1
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  DOI: 10.1016/j.xpro.2021.100314
  
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Redox-Sensitive Cysteines Confer Proximal Control of the Molecular Crowding Barrier in the Nuclear Pore

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1. scibot 17 Dec 2020
  
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  DOI: 10.1016/j.celrep.2020.108484
  
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Reelin-Nrp1 Interaction Regulates Neocortical Dendrite Development in a Context-Specific Manner

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  DOI: 10.1523/JNEUROSCI.1907-20.2020
  
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jneurosci.org/content/40/43/8248
Oct 2020
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Heterotrimeric G‐protein, Gi1, is involved in the regulation of proliferation, neuronal migration and dendrite morphology during cortical development in vivo

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1. scibot 23 Oct 2020
  
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  DOI: 10.1111/jnc.15205
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.15205
Sep 2020
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Ultrastructural Imaging of Activity-Dependent Synaptic Membrane-Trafficking Events in Cultured Brain Slices

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  DOI: 10.1016/j.neuron.2020.09.004
  
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Tandem Paired Nicking Promotes Precise Genome Editing with Scarce Interference by p53

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Iterative Single-Cell Analyses Define the Transcriptome of the First Functional Hematopoietic Stem Cells

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ORANGE: A CRISPR/Cas9-based genome editing toolbox for epitope tagging of endogenous proteins in neurons

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  DOI: 10.1371/journal.pbio.3000665
  
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Generation of Human Renal Vesicles in Mouse Organ Niche Using Nephron Progenitor Cell Replacement System

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Expression of SOLOIST/MRTFB i4, a novel neuronal isoform of the mouse serum response factor coactivator myocardin‐related transcription factor‐B, negatively regulates dendritic complexity in cortical neurons

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The LMTK1—TBC1D9B—Rab11A cascade regulates dendritic spine formation via endosome trafficking

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Targeting Endogenous K-RAS for Degradation through the Affinity-Directed Protein Missile System

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Dorsal-to-Ventral Cortical Expansion Is Physically Primed by Ventral Streaming of Early Embryonic Preplate Neurons

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Pituitary Adenylate Cyclase-Activating Polypeptide Modulates Dendritic Spine Maturation and Morphogenesis via MicroRNA-132 Upregulation

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Targeting Degradation of the Transcription Factor C/EBPβ Reduces Lung Fibrosis by Restoring Activity of the Ubiquitin-Editing Enzyme A20 in Macrophages

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Phosphorylation of Npas4 by MAPK Regulates Reward-Related Gene Expression and Behaviors

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  DOI: 10.1016/j.celrep.2019.10.116
  
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Amyloid-like Assembly Activates a Phosphatase in the Developing Drosophila Embryo

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  DOI: 10.1016/j.cell.2019.08.019
  
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AUTACs: Cargo-Specific Degraders Using Selective Autophagy

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NOX1-Dependent mTORC1 Activation via S100A9 Oxidation in Cancer Stem-like Cells Leads to Colon Cancer Progression

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Differential innervation within a transverse plane of spinal gray matter by sensorimotor cortices, with special reference to the somatosensory cortices

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  DOI: 10.1002/cne.24626
  
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Untitled document

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  DOI: 10.1002/jnr.24413
  
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Untitled document

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  DOI: 10.1016/j.devcel.2018.12.002
  
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A Functionally Defined In Vivo Astrocyte Population Identified by c-Fos Activation in a Mouse Model of Multiple Sclerosis Modulated by S1P Signaling: Immediate-Early Astrocytes (ieAstrocytes)

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Untitled document

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A Sialylated Voltage-Dependent Ca2+ Channel Binds Hemagglutinin and Mediates Influenza A Virus Entry into Mammalian Cells

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CD157 Marks Tissue-Resident Endothelial Stem Cells with Homeostatic and Regenerative Properties

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Cdk5 Regulation of the GRAB-Mediated Rab8-Rab11 Cascade in Axon Outgrowth

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Generation of Mouse and Human Organoid-Forming Intestinal Progenitor Cells by Direct Lineage Reprogramming

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Light-Dependent Regulation of Sleep and Wake States by Prokineticin 2 in Zebrafish

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High-Speed and Scalable Whole-Brain Imaging in Rodents and Primates

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Three‐dimensional analysis of somatic mitochondrial dynamics in fission‐deficient injured motor neurons using FIB/SEM

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TRIB3 Promotes APL Progression through Stabilization of the Oncoprotein PML-RARα and Inhibition of p53-Mediated Senescence

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Interspecies Chimerism with Mammalian Pluripotent Stem Cells

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Dynamic Remodeling of Membrane Composition Drives Cell Cycle through Primary Cilia Excision

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Reelin receptors ApoER2 and VLDLR are expressed in distinct spatiotemporal patterns in developing mouse cerebral cortex

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