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  1. Dec 2024
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Modeling Drug Responses and Evolutionary Dynamics using Patient-Derived Xenografts Reveals Precision Medicine Strategies for Triple Negative Breast Cancer
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    1. scibot 21 Dec 2024
      RRID:AB_626761

      DOI: 10.1158/0008-5472.CAN-24-1703

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    pmc.ncbi.nlm.nih.gov/articles/PMC7617242/
  3. academic.oup.com academic.oup.com
    CAF-1 promotes efficient PrimPol recruitment to nascent DNA for single-stranded DNA gap formation
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    1. scibot 13 Dec 2024
      Santa Cruz Biotechnology sc-6954

      DOI: 10.1093/nar/gkae1068

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    academic.oup.com/nar/advance-article/doi/10.1093/nar/gkae1068/7903364
  4. Nov 2024
  5. 52.53.155.43 52.53.155.43
    can-24-1703-html.html
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    1. scibot 14 Nov 2024
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  6. Jul 2024
  7. www.cell.com www.cell.com
    ADP-ribosylome analysis reveals homogeneous DNA-damage-induced serine ADP-ribosylation across wild-type and BRCA-mutant breast cancer cell lines
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    1. scibot 12 Jul 2024
      RRID:AB_626761

      DOI: 10.1016/j.celrep.2024.114433

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    cell.com/cell-reports/fulltext/S2211-1247(24)00762-9
  8. May 2024
  9. www.sciencedirect.com www.sciencedirect.com
    Loss of POLE3-POLE4 unleashes replicative gap accumulation upon treatment with PARP inhibitors
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    1. scibot 16 May 2024
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  10. Apr 2024
  11. rupress.org rupress.org
    DUX4-induced HSATII transcription causes KDM2A/B-PRC1 nuclear foci and impairs DNA damage response
    2
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    rupress.org/jcb/article/223/5/e202303141/276604/DUX4-induced-HSATII-transcription-causes-KDM2A-B
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    Targeting branched N-glycans and fucosylation sensitizes ovarian tumors to immune checkpoint blockade
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    1. scibot 03 Apr 2024
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      DOI: 10.1038/s41467-024-47069-y

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    nature.com/articles/s41467-024-47069-y
  13. Jan 2024
  14. www.sciencedirect.com www.sciencedirect.com
    BLM and BRCA1-BARD1 coordinate complementary mechanisms of joint DNA molecule resolution
    1
    1. scibot 25 Jan 2024
      RRID:AB_626761

      DOI: 10.1016/j.molcel.2023.12.040

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    sciencedirect.com/science/article/pii/S1097276523010869
  15. Apr 2023
  16. www.sciencedirect.com www.sciencedirect.com
    SLFN5-mediated chromatin dynamics sculpt higher-order DNA repair topology
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    1. scibot 06 Apr 2023
      RRID:AB_626761

      DOI: 10.1016/j.molcel.2023.02.004

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    sciencedirect.com/science/article/pii/S1097276523000837
  17. Feb 2023
  18. www.sciencedirect.com www.sciencedirect.com
    Microtubule-associated proteins MAP7 and MAP7D1 promote DNA double-strand break repair in the G1 cell cycle phase
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    1. scibot 17 Feb 2023
      RRID:AB_626761

      DOI: 10.1016/j.isci.2023.106107

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    sciencedirect.com/science/article/pii/S2589004223001840
  19. Jan 2023
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Temporal phosphoproteomics reveals WEE1-dependent control of 53BP1 pathway
    1
    1. scibot 11 Jan 2023
      RRID:AB_626761

      DOI: 10.1016/j.isci.2022.105806

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    ncbi.nlm.nih.gov/pmc/articles/PMC9827073/
  21. Dec 2022
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BRCA1 mediates protein homeostasis through the ubiquitination of PERK and IRE1
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    1. scibot 08 Dec 2022
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      DOI: 10.1016/j.isci.2022.105626

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    ncbi.nlm.nih.gov/pmc/articles/PMC9719099/
  23. Nov 2022
  24. www.sciencedirect.com www.sciencedirect.com
    POLθ processes ssDNA gaps and promotes replication fork progression in BRCA1-deficient cells
    1
    1. scibot 18 Nov 2022
      RRID:AB_626761

      DOI: 10.1016/j.celrep.2022.111716

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    sciencedirect.com/science/article/pii/S2211124722015947
  25. Sep 2022
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CANCER-ASSOCIATED SF3B1 MUTATIONS CONFER A BRCA-LIKE CELLULAR PHENOTYPE AND SYNTHETIC LETHALITY TO PARP INHIBITORS
    1
    1. scibot 02 Sep 2022
      RRID:AB_626761

      DOI: 10.1158/0008-5472.CAN-21-1843

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    ncbi.nlm.nih.gov/pmc/articles/PMC7612475/
  27. Apr 2022
  28. www.sciencedirect.com www.sciencedirect.com
    H3K4 methylation by SETD1A/BOD1L facilitates RIF1-dependent NHEJ
    1
    1. scibot 21 Apr 2022
      RRID:AB_626761

      DOI: 10.1016/j.molcel.2022.03.030

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    sciencedirect.com/science/article/pii/S1097276522002684
  29. Mar 2022
  30. www.sciencedirect.com www.sciencedirect.com
    BMI-1 regulates DNA end resection and homologous recombination repair
    1
    1. scibot 23 Mar 2022
      RRID:AB_626761

      DOI: 10.1016/j.celrep.2022.110536

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    sciencedirect.com/science/article/pii/S2211124722002777
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    Micropeptide PACMP inhibition elicits synthetic lethal effects by decreasing CtIP and poly(ADP-ribosyl)ation
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    1. scibot 02 Mar 2022
      RRID:AB_626761

      DOI: 10.1016/j.molcel.2022.01.020

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    sciencedirect.com/science/article/pii/S1097276522000855
  32. Dec 2021
  33. www.sciencedirect.com www.sciencedirect.com
    IFI16 inhibits DNA repair that potentiates type-I interferon-induced antitumor effects in triple negative breast cancer
    1
    1. scibot 22 Dec 2021
      RRID:AB_626761

      DOI: 10.1016/j.celrep.2021.110138

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    sciencedirect.com/science/article/pii/S221112472101634X
  34. Nov 2021
  35. www.sciencedirect.com www.sciencedirect.com
    A recurrent chromosomal inversion suffices for driving escape from oncogene-induced senescence via subTAD reorganization
    1
    1. scibot 18 Nov 2021
      RRID:AB_626761

      DOI: 10.1016/j.molcel.2021.10.017

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    sciencedirect.com/science/article/pii/S1097276521009096
  36. Sep 2021
  37. www.sciencedirect.com www.sciencedirect.com
    REV1-Polζ maintains the viability of homologous recombination-deficient cancer cells through mutagenic repair of PRIMPOL-dependent ssDNA gaps
    1
    1. scibot 11 Sep 2021
      RRID:AB_626761

      DOI: 10.1016/j.molcel.2021.08.016

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    sciencedirect.com/science/article/pii/S1097276521006833
  38. Jul 2021
  39. www.sciencedirect.com www.sciencedirect.com
    ASF1a Promotes Non-homologous End Joining Repair by Facilitating Phosphorylation of MDC1 by ATM at Double-Strand Breaks
    2
    1. scibot 28 Jul 2021
      AB_626761

      DOI: 10.1016/j.molcel.2017.08.021

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      DOI: 10.1016/j.molcel.2017.08.021

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    sciencedirect.com/science/article/pii/S1097276517306184
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cavin3 released from caveolae interacts with BRCA1 to regulate the cellular stress response
    1
    1. scibot 17 Jul 2021
      RRID:AB_626761

      DOI: 10.7554/eLife.61407

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    ncbi.nlm.nih.gov/pmc/articles/PMC8279762/
  41. Jun 2021
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ASPM promotes homologous recombination-mediated DNA repair by safeguarding BRCA1 stability
    1
    1. scibot 18 Jun 2021
      RRID:AB_626761

      DOI: 10.1016/j.isci.2021.102534

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    ncbi.nlm.nih.gov/pmc/articles/PMC8184511/
  43. www.sciencedirect.com www.sciencedirect.com
    Structural insight into BRCA1-BARD1 complex recruitment to damaged chromatin
    1
    1. scibot 08 Jun 2021
      RRID:AB_626761

      DOI: 10.1016/j.molcel.2021.05.010

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    sciencedirect.com/science/article/pii/S1097276521003671
  44. May 2021
  45. www.sciencedirect.com www.sciencedirect.com
    Helicobacter pylori CagA elicits BRCAness to induce genome instability that may underlie bacterial gastric carcinogenesis
    1
    1. scibot 14 May 2021
      RRID:AB_626761

      DOI: 10.1016/j.chom.2021.04.006

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    sciencedirect.com/science/article/pii/S1931312821001827
  46. www.sciencedirect.com www.sciencedirect.com
    Ubiquitin Phosphorylation at Thr12 Modulates the DNA Damage Response
    1
    1. scibot 07 May 2021
      RRID:AB_626761

      DOI: 10.1016/j.molcel.2020.09.017

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    sciencedirect.com/science/article/pii/S109727652030647X
  47. Apr 2021
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Elevated CXorf67 Expression in PFA Ependymomas Suppresses DNA Repair and Sensitizes to PARP Inhibitors
    1
    1. scibot 22 Apr 2021
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      DOI: 10.1016/j.ccell.2020.10.009

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    ncbi.nlm.nih.gov/pmc/articles/PMC8455074/
  49. www.sciencedirect.com www.sciencedirect.com
    Functional interrogation of DNA damage response variants with base editing screens
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    1. scibot 12 Apr 2021
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      DOI: 10.1016/j.cell.2021.01.041

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    sciencedirect.com/science/article/pii/S0092867421000842
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    SIRT2 promotes BRCA1-BARD1 heterodimerization through deacetylation
    1
    1. scibot 01 Apr 2021
      BRCA1

      DOI: 10.1016/j.celrep.2021.108921

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    sciencedirect.com/science/article/pii/S2211124721002357
  51. Feb 2021
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    Human DDK rescues stalled forks and counteracts checkpoint inhibition at unfired origins to complete DNA replication
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    sciencedirect.com/science/article/pii/S1097276521000046
  53. Jan 2021
  54. www.sciencedirect.com www.sciencedirect.com
    DCAF14 promotes stalled fork stability to maintain genome integrity
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      DOI: 10.1016/j.celrep.2020.108669

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    sciencedirect.com/science/article/pii/S2211124720316582
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    Proteome dynamics at broken replication forks reveal a distinct ATM-directed repair response suppressing DNA double-strand break ubiquitination
    1
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      DOI: 10.1016/j.molcel.2020.12.025

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    sciencedirect.com/science/article/pii/S1097276520309461
  56. Nov 2020
  57. www.sciencedirect.com www.sciencedirect.com
    PRDX1 Counteracts Catastrophic Telomeric Cleavage Events That Are Triggered by DNA Repair Activities Post Oxidative Damage
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      DOI: 10.1016/j.celrep.2020.108347

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    sciencedirect.com/science/article/pii/S221112472031336X
  58. Sep 2020
  59. www.sciencedirect.com www.sciencedirect.com
    Systematic Characterization of Recurrent Genomic Alterations in Cyclin-Dependent Kinases Reveals Potential Therapeutic Strategies for Cancer Treatment
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      DOI: 10.1016/j.celrep.2020.107884

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    sciencedirect.com/science/article/pii/S2211124720308652
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    BRCA1 Mutational Complementation Induces Synthetic Viability
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      DOI: 10.1016/j.molcel.2020.04.006

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    sciencedirect.com/science/article/pii/S109727652030232X
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    Phospho-Ser784-VCP Is Required for DNA Damage Response and Is Associated with Poor Prognosis of Chemotherapy-Treated Breast Cancer
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      RRID:AB_626761

      DOI: 10.1016/j.celrep.2020.107745

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    sciencedirect.com/science/article/pii/S2211124720307257
  62. genesdev.cshlp.org genesdev.cshlp.org
    Crosstalk between Lys63- and Lys11-polyubiquitin signaling at DNA damage sites is driven by Cezanne
    1
    1. scibot 04 Sep 2020
      BRCA1

      DOI: 10.1101/gad.332395.119

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      Curator comments: Mouse Anti-Human BRCA1 (D-9) Monoclonal, Unconjugated, Clone D-9 antibody Santa Cruz Biotechnology Cat# sc-6954

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      RRIDCUR:Missing RRID:AB_626761
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    genesdev.cshlp.org/content/33/23-24/1702.full
  63. Aug 2020
  64. www.sciencedirect.com www.sciencedirect.com
    FOXK1 Participates in DNA Damage Response by Controlling 53BP1 Function
    1
    1. scibot 30 Aug 2020
      AB_626761

      DOI: 10.1016/j.celrep.2020.108018

      Resource: (Santa Cruz Biotechnology Cat# sc-6954, RRID:AB_626761)

      Curator: @Naa003

      SciCrunch record: RRID:AB_626761

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      RRIDCUR:Validated RRID:AB_626761
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    sciencedirect.com/science/article/pii/S2211124720310032
  65. Jan 2020
  66. www.sciencedirect.com www.sciencedirect.com
    The Replisome Mediates A-NHEJ Repair of Telomeres Lacking POT1-TPP1 Independently of MRN Function
    1
    1. scibot 13 Jan 2020
      RRID:AB_626761

      DOI: 10.1016/j.celrep.2019.11.012

      Resource: (Santa Cruz Biotechnology Cat# sc-6954, RRID:AB_626761)

      Curator: @ethanbadger

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      RRID:AB_626761 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2211124719314834
  67. www.sciencedirect.com www.sciencedirect.com
    LMO2 Confers Synthetic Lethality to PARP Inhibition in DLBCL
    1
    1. scibot 13 Jan 2020
      RRID:AB_626761

      DOI: 10.1016/j.ccell.2019.07.007

      Resource: (Santa Cruz Biotechnology Cat# sc-6954, RRID:AB_626761)

      Curator: @ethanbadger

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      RRID:AB_626761 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1535610819303344
  68. www.sciencedirect.com www.sciencedirect.com
    Inadequate DNA Damage Repair Promotes Mammary Transdifferentiation, Leading to BRCA1 Breast Cancer
    1
    1. scibot 13 Jan 2020
      RRID:AB_626761

      DOI: 10.1016/j.cell.2019.06.002

      Resource: (Santa Cruz Biotechnology Cat# sc-6954, RRID:AB_626761)

      Curator: @ethanbadger

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      RRID:AB_626761 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0092867419306300
  69. www.sciencedirect.com www.sciencedirect.com
    Structural Basis of BRCC36 Function in DNA Repair and Immune Regulation
    1
    1. scibot 13 Jan 2020
      RRID:AB_626761

      DOI: 10.1016/j.molcel.2019.06.002

      Resource: (Santa Cruz Biotechnology Cat# sc-6954, RRID:AB_626761)

      Curator: @ethanbadger

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      RRID:AB_626761 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1097276519304356
  70. www.sciencedirect.com www.sciencedirect.com
    EXD2 Protects Stressed Replication Forks and Is Required for Cell Viability in the Absence of BRCA1/2
    1
    1. scibot 13 Jan 2020
      AB_626761

      DOI: 10.1016/j.molcel.2019.05.026

      Resource: (Santa Cruz Biotechnology Cat# sc-6954, RRID:AB_626761)

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      RRID:AB_626761 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1097276519303983
  71. www.embopress.org www.embopress.org
    The p97–Ataxin 3 complex regulates homeostasis of the DNA damage response E3 ubiquitin ligase RNF8
    1
    1. scibot 13 Jan 2020
      RRID:AB_626761

      DOI: 10.15252/embj.2019102361

      Resource: (Santa Cruz Biotechnology Cat# sc-6954, RRID:AB_626761)

      Curator: @Naa003

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      RRID:AB_626761 RRIDCUR:Validated
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    embopress.org/doi/10.15252/embj.2019102361
  72. www.sciencedirect.com www.sciencedirect.com
    Fork Cleavage-Religation Cycle and Active Transcription Mediate Replication Restart after Fork Stalling at Co-transcriptional R-Loops
    1
    1. scibot 13 Jan 2020
      RRID:AB_626761

      DOI: 10.1016/j.molcel.2019.10.026

      Resource: (Santa Cruz Biotechnology Cat# sc-6954, RRID:AB_626761)

      Curator: @ethanbadger

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      RRID:AB_626761 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1097276519308044
  73. www.sciencedirect.com www.sciencedirect.com
    DNA Damage Signaling-Induced Cancer Cell Reprogramming as a Driver of Tumor Relapse
    1
    1. scibot 13 Jan 2020
      RRID:AB_626761

      DOI: 10.1016/j.molcel.2019.03.002

      Resource: (Santa Cruz Biotechnology Cat# sc-6954, RRID:AB_626761)

      Curator: @ethanbadger

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      RRID:AB_626761 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1097276519301765
  74. Nov 2018
  75. www.sciencedirect.com www.sciencedirect.com
    CtIP-Mediated Fork Protection Synergizes with BRCA1 to Suppress Genomic Instability upon DNA Replication Stress
    1
    1. scibot 05 Nov 2018
      RRID:AB_626761

      Curator: @Jmenke

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      (Santa Cruz Biotechnology Cat# sc-6954, RRID:AB_626761)

      SciCrunch record: RRID:AB_626761

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:AB_626761 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1097276518307858
  76. www.sciencedirect.com www.sciencedirect.com
    Human Rad52 Promotes XPG-Mediated R-loop Processing to Initiate Transcription-Associated Homologous Recombination Repair
    1
    1. scibot 05 Nov 2018
      RRID:AB_626761

      Curator: @Jmenke

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      (Santa Cruz Biotechnology Cat# sc-6954, RRID:AB_626761)

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      RRID:AB_626761 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0092867418311176
  77. www.sciencedirect.com www.sciencedirect.com
    The Helicase PIF1 Facilitates Resection over Sequences Prone to Forming G4 Structures
    1
    1. scibot 05 Nov 2018
      RRID:AB_626761

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      (Santa Cruz Biotechnology Cat# sc-6954, RRID:AB_626761)

      SciCrunch record: RRID:AB_626761

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      RRID:AB_626761
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    sciencedirect.com/science/article/pii/S2211124718313330
  78. www.sciencedirect.com www.sciencedirect.com
    The Ubiquitin E3/E4 Ligase UBE4A Adjusts Protein Ubiquitylation and Accumulation at Sites of DNA Damage, Facilitating Double-Strand Break Repair
    1
    1. scibot 05 Nov 2018
      RRID:AB_626761

      Resource used:

      (Santa Cruz Biotechnology Cat# sc-6954, RRID:AB_626761)

      SciCrunch record: RRID:AB_626761

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      RRID:AB_626761
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    sciencedirect.com/science/article/pii/S109727651830100X
  79. www.sciencedirect.com www.sciencedirect.com
    BRD4 Inhibition Is Synthetic Lethal with PARP Inhibitors through the Induction of Homologous Recombination Deficiency
    1
    1. scibot 05 Nov 2018
      RRID:AB_626761

      Resource used:

      (Santa Cruz Biotechnology Cat# sc-6954, RRID:AB_626761)

      SciCrunch record: RRID:AB_626761

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:AB_626761
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    sciencedirect.com/science/article/pii/S1535610818300199
  80. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Targeting Phosphopeptide Recognition by the Human BRCA1 Tandem BRCT Domain to Interrupt BRCA1-Dependent Signaling
    1
    1. scibot 05 Nov 2018
      RRID:AB_626761

      Curator: @evieth

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      (Santa Cruz Biotechnology Cat# sc-6954, RRID:AB_626761)

      SciCrunch record: RRID:AB_626761

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:AB_626761 RRIDCUR:Validated
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    pubmed.ncbi.nlm.nih.gov/29606576/
  81. www.sciencedirect.com www.sciencedirect.com
    Replication Stress Shapes a Protective Chromatin Environment across Fragile Genomic Regions
    1
    1. scibot 05 Nov 2018
      RRID:AB_626761

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      (Santa Cruz Biotechnology Cat# sc-6954, RRID:AB_626761)

      SciCrunch record: RRID:AB_626761

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:AB_626761
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    sciencedirect.com/science/article/pii/S1097276517308808