34 Matching Annotations
  1. Oct 2025
  2. www.biorxiv.org www.biorxiv.org
    ACSS2-Mediated Metabolic-Epigenetic Crosstalk Drives Fulvestrant Resistance and Represents a Novel Therapeutic Target
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    biorxiv.org/content/10.1101/2025.09.23.678089v1
  3. Aug 2025
  4. www.biorxiv.org www.biorxiv.org
    Distinct 2-phenyl-imidazo[1, 2α] pyridine derivatives drive ER degradation and selectively impair proliferation of ER+ breast cancer cells via the aryl hydrocarbon receptor
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    biorxiv.org/content/10.1101/2025.07.28.666967v1
  5. Jun 2025
  6. www.sciencedirect.com www.sciencedirect.com
    Combined inhibition of KAT6A/B and Menin reverses estrogen receptor-driven gene expression programs in breast cancer
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    sciencedirect.com/science/article/pii/S2666379125002654
  7. elifesciences.org elifesciences.org
    Acute Activation of Genes Through Transcriptional Condensates Impact Non-target Genes in a Chromatin Domain
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    elifesciences.org/reviewed-preprints/102417v2
  8. May 2025
  9. www.sciencedirect.com www.sciencedirect.com
    Engineering ERα degraders with pleiotropic ubiquitin ligase ligands maximizes therapeutic efficacy by co-opting distinct effector ligases
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    sciencedirect.com/science/article/pii/S245194562500131X
  10. Feb 2025
  11. dx.doi.org dx.doi.org
    Progesterone Receptor Signaling Promotes Cancer Associated Fibroblast Mediated Tumorigenicity in ER+ Breast Cancer
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    dx.doi.org/10.1210/endocr/bqae092
  12. Dec 2024
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Canonical androgen response element motifs are tumor suppressive regulatory elements in the prostate
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    pmc.ncbi.nlm.nih.gov/articles/PMC11645413/
  14. Aug 2024
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cadmium activation of wild-type and constitutively active estrogen receptor alpha
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    ncbi.nlm.nih.gov/pmc/articles/PMC11341946/
  16. May 2024
  17. www.sciencedirect.com www.sciencedirect.com
    Estrogen promotes the progression of adenomyosis by inhibiting CITED2 through miR-145
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    sciencedirect.com/science/article/pii/S1472648324002979
  18. www.sciencedirect.com www.sciencedirect.com
    Tuft cell acetylcholine is released into the gut lumen to promote anti-helminth immunity
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    sciencedirect.com/science/article/pii/S1074761324002231
  19. Mar 2024
  20. www.sciencedirect.com www.sciencedirect.com
    CDK-independent role of D-type cyclins in regulating DNA mismatch repair
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    sciencedirect.com/science/article/pii/S1097276524001291
  21. Feb 2024
  22. genomebiology.biomedcentral.com genomebiology.biomedcentral.com
    The androgen receptor interacts with GATA3 to transcriptionally regulate a luminal epithelial cell phenotype in breast cancer
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    genomebiology.biomedcentral.com/articles/10.1186/s13059-023-03161-y
  23. Nov 2023
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tamoxifen for the treatment of myeloproliferative neoplasms: A Phase II clinical trial and exploratory analysis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10673935/
  25. Jul 2023
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of an Imidazopyridine-based Compound as an Oral Selective Estrogen Receptor Degrader for Breast Cancer Therapy
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    ncbi.nlm.nih.gov/pmc/articles/PMC10373600/
  27. Dec 2022
  28. www.sciencedirect.com www.sciencedirect.com
    AKTIP loss is enriched in ERα-positive breast cancer for tumorigenesis and confers endocrine resistance
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    sciencedirect.com/science/article/pii/S2211124722017132
  29. Nov 2022
  30. www.sciencedirect.com www.sciencedirect.com
    Estrone, the major postmenopausal estrogen, binds ERa to induce SNAI2, epithelial-to-mesenchymal transition, and ER+ breast cancer metastasis
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    sciencedirect.com/science/article/pii/S2211124722015467
  31. Feb 2022
  32. onlinelibrary.wiley.com onlinelibrary.wiley.com
    ERα inhibits mesenchymal and amoeboidal movement of liver cancer cell via Gα12
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    onlinelibrary.wiley.com/doi/10.1002/ijc.33929
  33. Jan 2022
  34. www.sciencedirect.com www.sciencedirect.com
    The portrait of liver cancer is shaped by mitochondrial genetics
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    sciencedirect.com/science/article/pii/S2211124721017666
  35. Nov 2021
  36. academic.oup.com academic.oup.com
    TXNIP links anticipatory unfolded protein response to estrogen reprogramming glucose metabolism in breast cancer cells
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    academic.oup.com/endo/article/163/1/bqab212/6382455
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Disrupted PGR-B and ESR1 signaling underlies defective decidualization linked to severe preeclampsia
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC8553341/
  38. Oct 2021
  39. academic.oup.com academic.oup.com
    Mechanisms of OCT4 on 3,5,3'-tri-iodothyronine and FSH-induced granulosa cell development in female mice
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    academic.oup.com/endo/article/162/11/bqab183/6360494
  40. Sep 2021
  41. www.sciencedirect.com www.sciencedirect.com
    ERα determines the chemoresistant function of mutant p53 involving the switch between lincRNA-p21 and DDB2 expressions
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    sciencedirect.com/science/article/pii/S2162253121001906
  42. Jul 2021
  43. www.nature.com www.nature.com
    Mitochondrial estrogen receptors alter mitochondrial priming and response to endocrine therapy in breast cancer cells
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    nature.com/articles/s41420-021-00573-2
  44. academic.oup.com academic.oup.com
    Selected Phytoestrogens Distinguish Roles of ERα Transactivation and Ligand Binding for Anti-Inflammatory Activity
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    academic.oup.com/endo/article/159/9/3351/5051602
  45. Apr 2021
  46. www.sciencedirect.com www.sciencedirect.com
    The Major Pre- and Postmenopausal Estrogens Play Opposing Roles in Obesity-Driven Mammary Inflammation and Breast Cancer Development
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    sciencedirect.com/science/article/pii/S1550413120302473
  47. www.cell.com www.cell.com
    IL6/STAT3 Signaling Hijacks Estrogen Receptor α Enhancers to Drive Breast Cancer Metastasis
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    cell.com/cancer-cell/fulltext/S1535-6108(20)30311-1
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GREB1: An evolutionarily conserved protein with a glycosyltransferase domain links ERα glycosylation and stability to cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC7968844/
  49. Mar 2021
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Estrogen receptor alpha in the brain mediates tamoxifen-induced changes in physiology in mice
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC7924955/
  51. Oct 2020
  52. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Coxsackievirus B Type 4 Infection in β Cells Downregulates the Chaperone Prefoldin URI to Induce a MODY4-like Diabetes via Pdx1 Silencing
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    pubmed.ncbi.nlm.nih.gov/33205075/
  53. Sep 2020
  54. www.nature.com www.nature.com
    A Systematic Study of the Impact of Estrogens and Selective Estrogen Receptor Modulators on Prostate Cancer Cell Proliferation
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    nature.com/articles/s41598-020-60844-3
  55. www.sciencedirect.com www.sciencedirect.com
    Structural Insights of Transcriptionally Active, Full-Length Androgen Receptor Coactivator Complexes
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    sciencedirect.com/science/article/pii/S1097276520304330
  56. www.sciencedirect.com www.sciencedirect.com
    Neurofibromin Is an Estrogen Receptor-α Transcriptional Co-repressor in Breast Cancer
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    sciencedirect.com/science/article/pii/S1535610820300921
  57. Jan 2020
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    ncbi.nlm.nih.gov/pmc/articles/PMC6336405/