321 Matching Annotations
  1. Dec 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Controlled aggregative assembly to form self-organizing macroscopic human intestine from induced pluripotent stem cells
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      DOI: 10.1016/j.crmeth.2024.100930

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    sciencedirect.com/science/article/pii/S2667237524003205
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    cTag-PAPERCLIP reveals alternative polyadenylation promotes cell-type specific protein diversity and switches Araf isoforms with microglia activation
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      DOI: 10.1016/j.neuron.2017.08.024

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  4. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004224028141-main-html.html
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    PNKP safeguards stalled replication forks from nuclease-dependent degradation during replication stress
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    1. scibot 14 Dec 2024
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      DOI: 10.1016/j.celrep.2024.115066

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    sciencedirect.com/science/article/pii/S2211124724014177
  6. Nov 2024
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    ARF alters PAF1 complex integrity to selectively repress oncogenic transcription programs upon p53 loss
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    sciencedirect.com/science/article/pii/S1097276524008608
  8. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Targeting ATAD3A Phosphorylation Mediated by TBK1 Ameliorates Senescence-Associated Pathologies
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      DOI: 10.1002/advs.202404109

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    TMEM39A and TMEM131 facilitate bulk transport of ECM proteins through large COPII vesicle formation
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    sciencedirect.com/science/article/pii/S167385272400287X
  10. Oct 2024
  11. www.sciencedirect.com www.sciencedirect.com
    A human organoid drug screen identifies α2-adrenergic receptor signaling as a therapeutic target for cartilage regeneration
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    sciencedirect.com/science/article/pii/S1934590924003151
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    Nucleoporin Nsp1 surveils the phase state of FG-Nups
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    sciencedirect.com/science/article/pii/S2211124724011446
  13. Sep 2024
  14. www.biorxiv.org www.biorxiv.org
    Type-II kinase inhibitors that target Parkinson’s Disease-associated LRRK2
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    1. scibot 28 Sep 2024
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    biorxiv.org/content/10.1101/2024.09.17.613365v1
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    Development of an adipose-tropic AAV capsid ablating liver tropism
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    sciencedirect.com/science/article/pii/S2589004224021552
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    A TBK1-independent primordial function of STING in lysosomal biogenesis
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    sciencedirect.com/science/article/pii/S1097276524007032
  17. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 25 Sep 2024
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      DOI: 10.1016/j.str.2018.12.002

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    sciencedirect.com/science/article/pii/S0969212618304581
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    Purification of micronuclei from cultured cells by flow cytometry
    1
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      DOI: 10.1016/j.xpro.2021.100378

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    sciencedirect.com/science/article/pii/S266616672100085X
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Netrin-1 and UNC5B Cooperate with Integrins to Mediate YAP-Driven Cytostasis
    1
    1. scibot 15 Sep 2024
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      DOI: 10.1158/2767-9764.CRC-24-0101

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    ncbi.nlm.nih.gov/pmc/articles/PMC11384508/
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dynamic remodeling of Septin structures fine-tunes myogenic differentiation
    1
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  21. www.sciencedirect.com www.sciencedirect.com
    Starvation-induced phosphorylation activates gasdermin A to initiate pyroptosis
    1
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    sciencedirect.com/science/article/pii/S2211124724010799
  22. www.sciencedirect.com www.sciencedirect.com
    Pooled endogenous protein tagging and recruitment for systematic profiling of protein function
    1
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      DOI: 10.1016/j.xgen.2024.100651

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    sciencedirect.com/science/article/pii/S2666979X24002623
  23. Aug 2024
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The tyrosine phosphatases LAR and PTPRδ act as receptors of the nidogen-tetanus toxin complex
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11329502/
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Maelstrom Represses Canonical Polymerase II Transcription within Bi-Directional piRNA Clusters in Drosophila melanogaster
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    1. scibot 21 Aug 2024
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      DOI: 10.1016/j.molcel.2018.10.038

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    ncbi.nlm.nih.gov/pmc/articles/PMC6551610/
  26. www.sciencedirect.com www.sciencedirect.com
    The divergent effects of G3BP orthologs on human stress granule assembly imply a centric role for the core protein interaction network
    1
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    sciencedirect.com/science/article/pii/S2211124724009677
  27. www.sciencedirect.com www.sciencedirect.com
    Oxidative stress reprograms the transcriptional coactivator Yki to suppress cell proliferation
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    sciencedirect.com/science/article/pii/S2211124724009136
  28. www.molbiolcell.org www.molbiolcell.org
    Ca<sup>2+</sup> entry through mechanotransduction channels localizes BAIAP2L2 to stereocilia tips
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      DOI: 10.1091/mbc.E21-10-0491

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  29. www.science.org www.science.org
    SERINC proteins potentiate antiviral type I IFN production and proinflammatory signaling pathways
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      sc-9996

      DOI: 10.1126/scisignal.abc7611

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  30. Jul 2024
  31. www.biorxiv.org www.biorxiv.org
    A disinhibitory basal forebrain to cortex projection supports sustained attention
    1
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      DOI: 10.1101/2024.07.22.604711

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    biorxiv.org/content/10.1101/2024.07.22.604711v1
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A CPF-like phosphatase module links transcription termination to chromatin silencing
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    1. scibot 26 Jul 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC7616277/
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ttm50 facilitates calpain activation by anchoring it to calcium stores and increasing its sensitivity to calcium
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      DOI: 10.1038/s41422-020-0388-4

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    ncbi.nlm.nih.gov/pmc/articles/PMC8115179/
  34. www.cell.com www.cell.com
    SART3 reads methylarginine-marked glycine- and arginine-rich motifs
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    cell.com/cell-reports/abstract/S2211-1247(24)00788-5
  35. www.embopress.org www.embopress.org
    The tyrosine phosphatases LAR and PTPRδ act as receptors of the nidogen-tetanus toxin complex
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    embopress.org/doi/10.1038/s44318-024-00164-8
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A phosphorylation-controlled switch confers cell cycle-dependent protein relocalization
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  37. Jun 2024
  38. www.sciencedirect.com www.sciencedirect.com
    A designed ankyrin-repeat protein that targets Parkinson’s disease-associated LRRK2
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    sciencedirect.com/science/article/pii/S0021925824019707
  39. May 2024
  40. www.sciencedirect.com www.sciencedirect.com
    Efficient expansion and CRISPR-Cas9-mediated gene correction of patient-derived hepatocytes for treatment of inherited liver diseases
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      DOI: 10.1016/j.stem.2024.04.022

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    sciencedirect.com/science/article/pii/S1934590924001772
  41. www.sciencedirect.com www.sciencedirect.com
    Autophagy preferentially degrades non-fibrillar polyQ aggregates
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    sciencedirect.com/science/article/pii/S1097276524003836
  42. www.sciencedirect.com www.sciencedirect.com
    Metabolic regulator ERRγ governs gastric stem cell differentiation into acid-secreting parietal cells
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    The phosphorylation landscape of infection-related development by the rice blast fungus
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    sciencedirect.com/science/article/pii/S0092867424004021
  44. www.sciencedirect.com www.sciencedirect.com
    A 5:2 intermittent fasting regimen ameliorates NASH and fibrosis and blunts HCC development via hepatic PPARα and PCK1
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    sciencedirect.com/science/article/pii/S1550413124001359
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Wybutosine hypomodification of tRNAphe activates HERVK and impairs neuronal differentiation
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    ncbi.nlm.nih.gov/pmc/articles/PMC11066470/
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of tumor suppressor TMEM127 drives RET-mediated transformation through disrupted membrane dynamics
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      DOI: 10.7554/eLife.89100

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    ncbi.nlm.nih.gov/pmc/articles/PMC11060712/
  47. Apr 2024
  48. rupress.org rupress.org
    WW domains form a folded type of nuclear localization signal to guide YAP1 nuclear import
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      DOI: 10.1083/jcb.202308013

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    rupress.org/jcb/article/223/6/e202308013/276631/WW-domains-form-a-folded-type-of-nuclear
  49. 52.53.155.43 52.53.155.43
    British J Pharmacology - 2024 - Wang - Differential contributions of G protein‐ or arrestin subtype‐mediated signalling-html.html
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  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Statins inhibit protein kinase D (PKD) activation in intestinal cells and prevent PKD1-induced growth of murine enteroids
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    Molecular determinants and signaling effects of PKA RIα phase separation
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    Selective targeting of Plasmodium falciparum Hsp90 disrupts the 26S proteasome
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    Anti-apoptotic MCL-1 promotes long-chain fatty acid oxidation through interaction with ACSL1
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    Protocol for the isolation of tumor cell-derived extracellular vesicles followed by in vivo metastasis assessment in a murine ovarian cancer model
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    BLMP-1 is a critical temporal regulator of dietary-restriction-induced response in Caenorhabditis elegans
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    Mea6/cTAGE5 cooperates with TRAPPC12 to regulate PTN secretion and white matter development
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    Mutations in the non-catalytic polyproline motif destabilize TREX1 and amplify cGAS-STING signaling
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    Histone lactylation inhibits RARγ expression in macrophages to promote colorectal tumorigenesis through activation of TRAF6-IL-6-STAT3 signaling
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    Multi-targeted loss of the antigen presentation molecule MR1 during HSV-1 and HSV-2 infection
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    The FANCI/FANCD2 complex links DNA damage response to R-loop regulation through SRSF1-mediated mRNA export
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    Golgi-to-ER retrograde transport prevents premature differentiation of Drosophila type II neuroblasts via Notch-signal-sending daughter cells
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    Prothymosin α accelerates dengue virus-induced thrombocytopenia
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    The circadian regulator PER1 promotes cell reprogramming by inhibiting inflammatory signaling from macrophages
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  69. Nov 2023
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    ABLs and TMKs are co-receptors for extracellular auxin
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    p120 RasGAP and ZO-2 are essential for Hippo signaling and tumor-suppressor function mediated by p190A RhoGAP
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    Small proteins modulate ion-channel-like ACD6 to regulate immunity in Arabidopsis thaliana
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    Dual agonistic and antagonistic roles of ZC3H18 provide for co-activation of distinct nuclear RNA decay pathways
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    Intrinsically disordered region-mediated condensation of IFN-inducible SCOTIN/SHISA-5 inhibits ER-to-Golgi vesicle transport
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    Parallel CRISPR-Cas9 screens identify mechanisms of PLIN2 and lipid droplet regulation
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  90. Jun 2023
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    Kv7/KCNQ potassium channels in cortical hyperexcitability and juvenile seizure-related death in Ank2-mutant mice
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    Methionine restriction promotes cGAS activation and chromatin untethering through demethylation to enhance antitumor immunity
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  97. May 2023
  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    Kupffer-cell-derived IL-6 is repurposed for hepatocyte dedifferentiation via activating progenitor genes from injury-specific enhancers
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    Polymerase iota (Pol ι) prevents PrimPol-mediated nascent DNA synthesis and chromosome instability
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    Non-Oncogene Addiction of KRAS-Mutant Cancers to IL-1&beta; via Versican and Mononuclear IKK&beta;
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    Negative regulation of TREM2-mediated C9orf72 poly-GA clearance by the NLRP3 inflammasome
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    Microtubule-associated proteins MAP7 and MAP7D1 promote DNA double-strand break repair in the G1 cell cycle phase
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    Molecular basis of eIF5A-dependent CAT tailing in eukaryotic ribosome-associated quality control
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    Crk proteins activate the Rap1 guanine nucleotide exchange factor C3G by segregated adaptor-dependent and -independent mechanisms
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    Host-symbiont interactions in Angomonas deanei include the evolution of a host-derived dynamin ring around the endosymbiont division site
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    Structural insights into caspase ADPR deacylization catalyzed by a bacterial effector and host calmodulin
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    Ubiquitination and deubiquitination of 4E-T regulate neural progenitor cell maintenance and neurogenesis by controlling P-body formation
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    Phase separation of HRLP regulates flowering time in Arabidopsis
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    Protein disulfide isomerase PDI-6 regulates Wnt secretion to coordinate inter-tissue UPRmt activation and lifespan extension in C. elegans
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    The Taspase1/Myosin1f-axis regulates filopodia dynamics
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  150. aacrjournals.org aacrjournals.org
    Melanoma-secreted Amyloid Beta Suppresses Neuroinflammation and Promotes Brain Metastasis
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    Retinoic acid-induced protein 14 controls dendritic spine dynamics associated with depressive-like behaviors
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    Expression of p11 and heteromeric TASK channels in mouse adrenal cortical cells and H295R cells
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  154. Apr 2022
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    Hedgehog-responsive PDGFRa(+) fibroblasts maintain a unique pool of alveolar epithelial progenitor cells during alveologenesis
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    Tel2 regulates redifferentiation of bipotential progenitor cells via Hhex during zebrafish liver regeneration
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    Ca2+ entry through mechanotransduction channels localizes BAIAP2L2 to stereocilia tips
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    BMI-1 regulates DNA end resection and homologous recombination repair
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    EB1- and EB2-dependent anterograde trafficking of TRPM4 regulates focal adhesion turnover and cell invasion
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    F-box protein FBXO41 plays vital role in arsenic trioxide-mediated autophagic death of cancer cells
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    K48/K63-linked polyubiquitination of ATG9A by TRAF6 E3 ligase regulates oxidative stress-induced autophagy
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  164. Feb 2022
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    A phosphoswitch at acinus-serine437 controls autophagic responses to cadmium exposure and neurodegenerative stress
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    The SH2 domain and kinase activity of JAK2 target JAK2 to centrosome and regulate cell growth and centrosome amplification
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  167. Dec 2021
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    Direct inhibition of phosphate transport by immune signaling in Arabidopsis
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    Mechano-transduction via the pectin-FERONIA complex activates ROP6 GTPase signaling in Arabidopsis pavement cell morphogenesis
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    Arabidopsis pavement cell morphogenesis requires FERONIA binding to pectin for activation of ROP GTPase signaling
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    A Genetically Encoded Picolyl Azide for Improved Live Cell Copper Click Labeling
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  173. www.embopress.org www.embopress.org
    Single-cell transcriptomics identifies Gadd45b as a regulator of herpesvirus-reactivating neurons
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  174. elifesciences.org elifesciences.org
    Selective sorting of microRNAs into exosomes by phase-separated YBX1 condensates
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  175. Nov 2021
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    Function and molecular mechanism of N-terminal acetylation in autophagy
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    ADAR1 restricts ZBP1-mediated immune response and PANoptosis to promote tumorigenesis
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    Secondary metabolites of Hülle cells mediate protection of fungal reproductive and overwintering structures against fungivorous animals
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    Interactome analysis reveals endocytosis and membrane recycling of EpCAM during differentiation of embryonic stem cells and carcinoma cells
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    Regulation of synapse weakening through interactions of the microtubule associated protein tau with PACSIN1
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  182. Sep 2021
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    Acute brain vascular regeneration occurs via lymphatic transdifferentiation
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    Parasitic modulation of host development by ubiquitin-independent protein degradation
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    Translational control of polyamine metabolism by CNBP is required for Drosophila locomotor function
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    Cyclical phosphorylation of LRAP35a and CLASP2 by GSK3β and CK1δ regulates EB1-dependent MT dynamics in cell migration
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    Characterization of the subunit composition and structure of adult human glycine receptors
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    FAN1 controls mismatch repair complex assembly via MLH1 retention to stabilize CAG repeat expansion in Huntington’s disease
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    Induced phase separation of mutant NF2 imprisons the cGAS-STING machinery to abrogate antitumor immunity
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    Autophagic elimination of ribosomes during spermiogenesis provides energy for flagellar motility
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    Molecular and cellular basis of hyperassembly and protein aggregation driven by a rare pathogenic mutation in DDX3X
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  193. www.nature.com www.nature.com
    UbiB proteins regulate cellular CoQ distribution in Saccharomyces cerevisiae
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    Investigation of Ldb19/Art1 localization and function at the late Golgi
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    GFP-Mutant Human Tau Transgenic Mice Develop Tauopathy Following CNS Injections of Alzheimer's Brain-Derived Pathological Tau or Synthetic Mutant Human Tau Fibrils
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    cindr, the Drosophila Homolog of the CD2AP Alzheimer’s Disease Risk Gene, Is Required for Synaptic Transmission and Proteostasis
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    Distinct Roles of RZZ and Bub1-KNL1 in Mitotic Checkpoint Signaling and Kinetochore Expansion
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    The Mammalian Malonyl-CoA Synthetase ACSF3 Is Required for Mitochondrial Protein Malonylation and Metabolic Efficiency
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    A Viral Receptor Complementation Strategy to Overcome CAV-2 Tropism for Efficient Retrograde Targeting of Neurons
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    TBK1-Mediated DRP1 Targeting Confers Nucleic Acid Sensing to Reprogram Mitochondrial Dynamics and Physiology
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    Ectosomal PKM2 Promotes HCC by Inducing Macrophage Differentiation and Remodeling the Tumor Microenvironment
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    Tyrosine Phosphorylation of the Myosin Regulatory Light Chain Controls Non-muscle Myosin II Assembly and Function in Migrating Cells
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    Di-methylation of CD147-K234 Promotes the Progression of NSCLC by Enhancing Lactate Export
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    Selective Inhibition of STRN3-Containing PP2A Phosphatase Restores Hippo Tumor-Suppressor Activity in Gastric Cancer
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    cGAS phase separation inhibits TREX1-mediated DNA degradation and enhances cytosolic DNA sensing
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