204 Matching Annotations
  1. Last 7 days
  2. www.science.org www.science.org
    ARL3 GTPases facilitate ODA16 unloading from IFT in motile cilia
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    1. scibot 20 Dec 2024
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      DOI: 10.1126/sciadv.adq2950

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  3. Dec 2024
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    BMP suppresses Wnt signaling via the Bcl11b-regulated NuRD complex to maintain intestinal stem cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC11612440/
  5. Nov 2024
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Non-autophagic Golgi-LC3 lipidation facilitates TFE3 stress response against Golgi dysfunction
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    1. scibot 08 Nov 2024
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    pmc.ncbi.nlm.nih.gov/articles/PMC11535212/
  7. Oct 2024
  8. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    ERK1/2 mitogen-activated protein kinase dimerization is essential for the regulation of cell motility
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    1. scibot 04 Oct 2024
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      DOI: 10.1002/1878-0261.13732

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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.13732
  9. Sep 2024
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ARL3 GTPases facilitate ODA16 unloading from IFT in motile cilia
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    1. scibot 12 Sep 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11373600/
  11. Aug 2024
  12. www.sciencedirect.com www.sciencedirect.com
    Histone chaperone HIRA, promyelocytic leukemia protein, and p62/SQSTM1 coordinate to regulate inflammation during cell senescence
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    1. scibot 23 Aug 2024
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    sciencedirect.com/science/article/pii/S1097276524006609
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ubiquitin-specific peptidase 22 controls integrin-dependent cancer cell stemness and metastasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11378969/
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    The divergent effects of G3BP orthologs on human stress granule assembly imply a centric role for the core protein interaction network
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    1. scibot 20 Aug 2024
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    sciencedirect.com/science/article/pii/S2211124724009677
  15. Jun 2024
  16. link.springer.com link.springer.com
    ATG16L1 induces the formation of phagophore-like membrane cups
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      DOI: 10.1038/s41594-024-01300-y

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    link.springer.com/article/10.1038/s41594-024-01300-y
  17. May 2024
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Swd2/Cps35 determines H3K4 tri-methylation via interactions with Set1 and Rad6
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    1. scibot 09 May 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11069235/
  19. Apr 2024
  20. www.sciencedirect.com www.sciencedirect.com
    O-GlcNAcylation of RBM14 contributes to elevated cellular O-GlcNAc through regulation of OGA protein stability
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    1. scibot 30 Apr 2024
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    sciencedirect.com/science/article/pii/S2211124724004911
  21. www.nature.com www.nature.com
    Cross-link assisted spatial proteomics to map sub-organelle proteomes and membrane protein topologies
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    1. scibot 18 Apr 2024
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      DOI: 10.1038/s41467-024-47569-x

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    nature.com/articles/s41467-024-47569-x
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    NLRP3 Cys126 palmitoylation by ZDHHC7 promotes inflammasome activation
    2
    1. scibot 09 Apr 2024
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    pmc.ncbi.nlm.nih.gov/articles/PMC11130711/
  23. www.sciencedirect.com www.sciencedirect.com
    Central inhibition of HDAC6 re-sensitizes leptin signaling during obesity to induce profound weight loss
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    sciencedirect.com/science/article/pii/S1550413124000536
  24. dx.doi.org dx.doi.org
    The role of microtubule-associated protein tau in netrin-1 attractive signaling
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    1. scibot 04 Apr 2024
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      DOI: 10.1242/jcs.261244

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    dx.doi.org/10.1242/jcs.261244
  25. Mar 2024
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    VCF1 is a p97/VCP cofactor promoting recognition of ubiquitylated p97-UFD1-NPL4 substrates
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    1. scibot 22 Mar 2024
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      DOI: 10.1038/s41467-024-46760-4

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    ncbi.nlm.nih.gov/pmc/articles/PMC10950897/
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Long noncoding RNA Malat1 protects against osteoporosis and bone metastasis
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    1. scibot 19 Mar 2024
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      DOI: 10.1038/s41467-024-46602-3

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    ncbi.nlm.nih.gov/pmc/articles/PMC10944492/
  28. www.sciencedirect.com www.sciencedirect.com
    MOF-mediated acetylation of UHRF1 enhances UHRF1 E3 ligase activity to facilitate DNA methylation maintenance
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    sciencedirect.com/science/article/pii/S2211124724002365
  29. Feb 2024
  30. www.sciencedirect.com www.sciencedirect.com
    DUB3 is a MAGEA3 deubiquitinase and a potential therapeutic target in hepatocellular carcinoma
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    1. scibot 29 Feb 2024
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      DOI: 10.1016/j.isci.2024.109181

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      DOI: 10.1016/j.isci.2024.109181

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      DOI: 10.1016/j.isci.2024.109181

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    sciencedirect.com/science/article/pii/S2589004224004024
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    mtDNA extramitochondrial replication mediates mitochondrial defect effects
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    ncbi.nlm.nih.gov/pmc/articles/PMC10844862/
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cullin-RING E3 ubiquitin ligase 4 regulates neurite morphogenesis during neurodevelopment
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    ncbi.nlm.nih.gov/pmc/articles/PMC10839267/
  33. Jan 2024
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Riboproteome remodelling during quiescence exit in Saccharomyces cerevisiae
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    1. scibot 20 Jan 2024
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      DOI: 10.1016/j.isci.2023.108727

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    ncbi.nlm.nih.gov/pmc/articles/PMC10792236/
  35. www.sciencedirect.com www.sciencedirect.com
    Discovery of galectin-8 as an LILRB4 ligand driving M-MDSCs defines a class of antibodies to fight solid tumors
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      DOI: 10.1016/j.xcrm.2023.101374

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    sciencedirect.com/science/article/pii/S2666379123006031
  36. www.sciencedirect.com www.sciencedirect.com
    Extracellular pectin-RALF phase separation mediates FERONIA global signaling function
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      DOI: 10.1016/j.cell.2023.11.038

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    sciencedirect.com/science/article/pii/S0092867423013247
  37. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Pirin Inhibits FAS-Mediated Apoptosis to Support Colorectal Cancer Survival
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      DOI: 10.1002/advs.202301476

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    onlinelibrary.wiley.com/doi/full/10.1002/advs.202301476
  38. Dec 2023
  39. www.sciencedirect.com www.sciencedirect.com
    Programmable modulation of ribosomal frameshifting by mRNA targeting CRISPR-Cas12a system
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    1. scibot 02 Dec 2023
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    sciencedirect.com/science/article/pii/S2589004223025695
  40. Nov 2023
  41. www.sciencedirect.com www.sciencedirect.com
    BACH1 regulates the differentiation of vascular smooth muscle cells from human embryonic stem cells via CARM1-mediated methylation of H3R17
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    1. scibot 28 Nov 2023
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      DOI: 10.1016/j.celrep.2023.113468

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    sciencedirect.com/science/article/pii/S2211124723014808
  42. www.sciencedirect.com www.sciencedirect.com
    mTORC1 promotes cell growth via m6A-dependent mRNA degradation
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    1. scibot 09 Nov 2023
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      DOI: 10.1016/j.molcel.2021.03.010

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    sciencedirect.com/science/article/pii/S1097276521001787
  43. www.biorxiv.org www.biorxiv.org
    Collapse of late endosomal pH elicits a rapid Rab7 response via V-ATPase and RILP
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      DOI: 10.1101/2023.10.24.563658

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    biorxiv.org/content/10.1101/2023.10.24.563658v1
  44. Oct 2023
  45. www.sciencedirect.com www.sciencedirect.com
    β1 integrin signaling governs necroptosis via the chromatin-remodeling factor CHD4
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      DOI: 10.1016/j.celrep.2023.113322

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    sciencedirect.com/science/article/pii/S2211124723013347
  46. www.sciencedirect.com www.sciencedirect.com
    Nuclear import carrier Hikeshi cooperates with HSP70 to promote murine oligodendrocyte differentiation and CNS myelination
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    sciencedirect.com/science/article/pii/S1534580723004896
  47. www.sciencedirect.com www.sciencedirect.com
    Intrinsically disordered region-mediated condensation of IFN-inducible SCOTIN/SHISA-5 inhibits ER-to-Golgi vesicle transport
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    sciencedirect.com/science/article/pii/S1534580723004458
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    S-acylation of p62 promotes p62 droplet recruitment into autophagosomes in mammalian autophagy
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    ncbi.nlm.nih.gov/pmc/articles/PMC10552648/
  49. www.cell.com www.cell.com
    Methylation of KRAS by SETD7 promotes KRAS degradation in non-small cell lung cancer
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      DOI: 10.1016/j.celrep.2023.113003

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    cell.com/cell-reports/abstract/S2211-1247(23)01014-8
  50. www.sciencedirect.com www.sciencedirect.com
    Regulation of ERK2 activity by dynamic S-acylation
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      DOI: 10.1016/j.celrep.2023.113135

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    sciencedirect.com/science/article/pii/S2211124723011476
  51. Sep 2023
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CHIP protects against septic acute kidney injury by inhibiting NLRP3-mediated pyroptosis
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      DOI: 10.1016/j.isci.2023.107762

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    ncbi.nlm.nih.gov/pmc/articles/PMC10492219/
  53. Aug 2023
  54. 52.53.155.43 52.53.155.43
    The miR-17∼92 miRNAs promote plasma cell differentiation by suppressing SOCS3-mediated NIK degradation
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      DOI: 10.1016/j.celrep.2023.112968

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      DOI: 10.1016/j.celrep.2023.112968

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    52.53.155.43/8a075ef675e11ca05cb4fe9fd629f036036ec570/PIIS2211124723009798-html.html
  55. Jul 2023
  56. www.sciencedirect.com www.sciencedirect.com
    HIB/SPOP inhibits Ci/Gli-mediated tumorigenesis by modulating the RNA Polymerase II components stabilities
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    GAPDH facilitates homologous recombination repair by stabilizing RAD51 in an HDAC1-dependent manner
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  59. Jun 2023
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    SENP3-mediated deSUMOylation of c-Jun facilitates microglia-induced neuroinflammation after cerebral ischemia and reperfusion injury
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    KS10076, a chelator for redox-active metal ions, induces ROS-mediated STAT3 degradation in autophagic cell death and eliminates ALDH1+ stem cells
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  66. Apr 2023
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    Interaction between GPR110 (ADGRF1) and tight junction protein occludin implicated in blood-brain barrier permeability
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    ER-localized JmjC domain-containing protein JMJD8 targets STING to promote immune evasion and tumor growth in breast cancer
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    m6A modification confers thermal vulnerability to HPV E7 oncotranscripts via reverse regulation of its reader protein IGF2BP1 upon heat stress
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  82. Aug 2022
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    The AMPK-HOXB9-KRAS axis regulates lung adenocarcinoma growth in response to cellular energy alterations
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    Mediator recruits the cohesin loader Scc2 to RNA Pol II-transcribed genes and promotes sister chromatid cohesion
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    WWC proteins mediate LATS1/2 activation by Hippo kinases and imply a tumor suppression strategy
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    Semaphorin3A/PlexinA3 association with the Scribble scaffold for cGMP increase is required for apical dendrite development
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  101. Dec 2021
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  106. Nov 2021
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    HRD1-mediated METTL14 degradation regulates m6A mRNA modification to suppress ER proteotoxic liver disease
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    Function and molecular mechanism of N-terminal acetylation in autophagy
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    SdhA blocks disruption of the Legionella-containing vacuole by hijacking the OCRL phosphatase
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  110. Oct 2021
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  112. Sep 2021
  113. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Translational control of polyamine metabolism by CNBP is required for Drosophila locomotor function
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    MAP4K4 Inhibition Promotes Survival of Human Stem Cell-Derived Cardiomyocytes and Reduces Infarct Size In Vivo
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    Tinagl1 Suppresses Triple-Negative Breast Cancer Progression and Metastasis by Simultaneously Inhibiting Integrin/FAK and EGFR Signaling
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    Foxp1 Is Indispensable for Ductal Morphogenesis and Controls the Exit of Mammary Stem Cells from Quiescence
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    Mitochondrial Sirtuin Network Reveals Dynamic SIRT3-Dependent Deacetylation in Response to Membrane Depolarization
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    SREBP-1c impairs ULK1 sulfhydration-mediated autophagic flux to promote hepatic steatosis in high-fat-diet-fed mice
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    A Role for the Mre11-Rad50-Xrs2 Complex in Gene Expression and Chromosome Organization
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    DNA Damage-Induced Nucleosome Depletion Enhances Homology Search Independently of Local Break Movement
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    The Mammalian Crumbs Complex Defines a Distinct Polarity Domain Apical of Epithelial Tight Junctions
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    Pharmacological Targeting of Vacuolar H+-ATPase via Subunit V1G Combats Multidrug-Resistant Cancer
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    Regulation of the endocytosis and prion-chaperoning machineries by yeast E3 ubiquitin ligase Rsp5 as revealed by orthogonal ubiquitin transfer
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    mTORC1 promotes cell growth via m6A-dependent mRNA degradation
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    Centromeric chromatin integrity is compromised by loss of Cdk5rap2, a transcriptional activator of CENP-A
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    Oligodendrocytes Provide Antioxidant Defense Function for Neurons by Secreting Ferritin Heavy Chain
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  159. Feb 2021
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    Structure of the catalytic core of the Integrator complex
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    Expression of p11 and Heteromeric TASK Channels in Rat Carotid Body Glomus Cells and Nerve Growth Factor–differentiated PC12 Cells - Hidetada Matsuoka, Mieczyslaw Pokorski, Keita Harada, Reiji Yoshimura, Masumi Inoue, 2020
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  162. www.cell.com www.cell.com
    Mitochondrial Sirtuin Network Reveals Dynamic SIRT3-Dependent Deacetylation in Response to Membrane Depolarization
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  163. Jan 2021
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    Biomolecular condensation of NUP98 fusion proteins drives leukemogenic gene expression
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  165. Dec 2020
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    The deubiquitylase Ubp15 couples transcription to mRNA export
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    BLOS1 mediates kinesin switch during endosomal recycling of LDL receptor
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  168. Nov 2020
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    A Selective Autophagy Pathway for Phase-Separated Endocytic Protein Deposits
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  170. Oct 2020
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    AMPK promotes SPOP-mediated NANOG degradation to regulate prostate cancer cell stemness
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  172. Sep 2020
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    A Localized Scaffold for cGMP Increase Is Required for Apical Dendrite Development
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    c-Src Promotes Tumorigenesis and Tumor Progression by Activating PFKFB3
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    Loratadine, an antihistamine drug, exhibits anti-inflammatory activity through suppression of the NF-kB pathway
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    Microtubule Nucleation Properties of Single Human γTuRCs Explained by Their Cryo-EM Structure
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    Slo2 potassium channel function depends on RNA editing-regulated expression of a SCYL1 protein
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    RabX1 Organizes a Late Endosomal Compartment that Forms Tubular Connections to Lysosomes Consistent with a “Kiss and Run” Mechanism
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    Mec1 Is Activated at the Onset of Normal S Phase by Low-dNTP Pools Impeding DNA Replication
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    Microbial Imidazole Propionate Affects Responses to Metformin through p38γ-Dependent Inhibitory AMPK Phosphorylation
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    Bacteria Boost Mammalian Host NAD Metabolism by Engaging the Deamidated Biosynthesis Pathway
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    The Cyclopeptide Astin C Specifically Inhibits the Innate Immune CDN Sensor STING
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  185. bmcbiol.biomedcentral.com bmcbiol.biomedcentral.com
    RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination
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      mouse monoclonal anti-HA-probe HRP

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    NMT1 and NMT2 are lysine myristoyltransferases regulating the ARF6 GTPase cycle
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    ZAKα Recognizes Stalled Ribosomes through Partially Redundant Sensor Domains
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    Modular and Distinct Plexin-A4/FARP2/Rac1 Signaling Controls Dendrite Morphogenesis
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      monoclonal mouse anti-HA

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    Genetic ablation of the mitoribosome in the malaria parasite Plasmodium falciparum sensitizes it to antimalarials that target mitochondrial functions
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      mouse monoclonal anti-HA primary antibody

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  190. Jan 2020
  191. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Protective roles of carbonic anhydrase 8 in Machado–Joseph Disease
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    Phosphorylation of Ci/Gli by Fused Family Kinases Promotes Hedgehog Signaling
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    Cdc14 and PP2A Phosphatases Cooperate to Shape Phosphoproteome Dynamics during Mitotic Exit
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    Muscarinic receptor stimulation induces TASK1 channel endocytosis through a PKC-Pyk2-Src pathway in PC12 cells
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    NFE2L3 Controls Colon Cancer Cell Growth through Regulation of DUX4, a CDK1 Inhibitor
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    LC3C-Mediated Autophagy Selectively Regulates the Met RTK and HGF-Stimulated Migration and Invasion
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    CD146 Regulates Growth Factor-Induced mTORC2 Activity Independent of the PI3K and mTORC1 Pathways
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    Regulation of Phosphoribosyl-Linked Serine Ubiquitination by Deubiquitinases DupA and DupB
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    MRX Increases Chromatin Accessibility at Stalled Replication Forks to Promote Nascent DNA Resection and Cohesin Loading
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    Histone Recycling by FACT and Spt6 during Transcription Prevents the Scrambling of Histone Modifications
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    Mutant FUS and ELAVL4 (HuD) Aberrant Crosstalk in Amyotrophic Lateral Sclerosis
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    Phosphorylation-mediated interactions with TOPBP1 couple 53BP1 and 9-1-1 to control the G1 DNA damage checkpoint
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  203. www.cell.com www.cell.com
    A Variant of SLC1A5 Is a Mitochondrial Glutamine Transporter for Metabolic Reprogramming in Cancer Cells
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    Transient Receptor Potential V Channels Are Essential for Glucose Sensing by Aldolase and AMPK
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    Molecular Basis of Natural Variation in Photoperiodic Flowering Responses
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    Dynamic Incorporation of Histone H3 Variants into Chromatin Is Essential for Acquisition of Aggressive Traits and Metastatic Colonization
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    53BP1 Supports Immunoglobulin Class Switch Recombination Independently of Its DNA Double-Strand Break End Protection Function
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    The Deubiquitinase USP46 Is Essential for Proliferation and Tumor Growth of HPV-Transformed Cancers
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    Nucleoporin Seh1 Interacts with Olig2/Brd7 to Promote Oligodendrocyte Differentiation and Myelination
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    FYCO1 mediates clearance of α‐synuclein aggregates through a Rab7‐dependent mechanism
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    miR-92 Suppresses Robo1 Translation to Modulate Slit Sensitivity in Commissural Axon Guidance
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    BLM Potentiates c-Jun Degradation and Alters Its Function as an Oncogenic Transcription Factor
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    LSD1 Ablation Stimulates Anti-tumor Immunity and Enables Checkpoint Blockade
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    EP300-Mediated Lysine 2-Hydroxyisobutyrylation Regulates Glycolysis
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    The InR/Akt/TORC1 Growth-Promoting Signaling Negatively Regulates JAK/STAT Activity and Migratory Cell Fate during Morphogenesis
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    Sense-Antisense lncRNA Pair Encoded by Locus 6p22.3 Determines Neuroblastoma Susceptibility via the USP36-CHD7-SOX9 Regulatory Axis
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    AIDA Selectively Mediates Downregulation of Fat Synthesis Enzymes by ERAD to Retard Intestinal Fat Absorption and Prevent Obesity
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    Gq activity- and β-arrestin-1 scaffolding-mediated ADGRG2/CFTR coupling are required for male fertility
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    Molecular Dissection of Neuroligin 2 and Slitrk3 Reveals an Essential Framework for GABAergic Synapse Development
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    CLOCK Acetylates ASS1 to Drive Circadian Rhythm of Ureagenesis
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    A Genetic Tool to Track Protein Aggregates and Control Prion Inheritance
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    A Balance of Yki/Sd Activator and E2F1/Sd Repressor Complexes Controls Cell Survival and Affects Organ Size
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    H3.3K27M Cooperates with Trp53 Loss and PDGFRA Gain in Mouse Embryonic Neural Progenitor Cells to Induce Invasive High-Grade Gliomas
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  236. Nov 2017
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    The Structure of the ZMYND8/Drebrin Complex Suggests a Cytoplasmic Sequestering Mechanism of ZMYND8 by Drebrin
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    Prosapip1-Dependent Synaptic Adaptations in the Nucleus Accumbens Drive Alcohol Intake, Seeking, and Reward
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    In vitro analysis of RQC activities provides insights into the mechanism and function of CAT tailing
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    A UTX-MLL4-p300 Transcriptional Regulatory Network Coordinately Shapes Active Enhancer Landscapes for Eliciting Transcription
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    Exosome RNA Unshielding Couples Stromal Activation to Pattern Recognition Receptor Signaling in Cancer
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    Structural Basis for Specific Interaction of TGFβ Signaling Regulators SARA/Endofin with HD-PTP
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    The Sec14-like phosphatidylinositol transfer proteins Sec14l3/SEC14L2 act as GTPase proteins to mediate Wnt/Ca2+ signaling
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    Matching NLR Immune Receptors to Autoimmunity in camta3 Mutants Using Antimorphic NLR Alleles
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