Hypothesis

26 Matching Annotations

Nov 2025
www.sciencedirect.com www.sciencedirect.com

USP10-mediated deubiquitination and activation of KRAS mutants promotes colorectal cancer via a novel USP10/KRAS positive feedback circuit

1
1. scibot 18 Nov 2025
  
  in Public
  
  RRID:AB_627865
  
  DOI: 10.1016/j.apsb.2025.11.015
  
  Resource: (Santa Cruz Biotechnology Cat# sc-30, RRID:AB_627865)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_627865
  
  What is this?
  
  RRID:AB_627865
Visit annotations in context

Tags

RRID:AB_627865

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211383525007452
Oct 2025
www.nature.com www.nature.com

Modeling response to the KRAS-G12C inhibitor AZD4625 in KRASG12C NSCLC patient-derived xenografts reveals insights into primary resistance mechanisms

1
1. scibot 23 Oct 2025
  
  in Public
  
  RRID:AB_627865
  
  DOI: 10.1038/s41416-025-03216-w
  
  Resource: (Santa Cruz Biotechnology Cat# sc-30, RRID:AB_627865)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_627865
  
  What is this?
  
  RRID:AB_627865
Visit annotations in context

Tags

RRID:AB_627865

Annotators

scibot

URL

nature.com/articles/s41416-025-03216-w
Jul 2025
www.sciencedirect.com www.sciencedirect.com

Therapeutic targeting of syndecan-1 axis overcomes acquired resistance to KRAS-targeted therapy in gastrointestinal cancers

1
1. scibot 29 Jul 2025
  
  in Public
  
  RRID:AB_627865
  
  DOI: 10.1016/j.xcrm.2025.102253
  
  Resource: (Santa Cruz Biotechnology Cat# sc-30, RRID:AB_627865)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_627865
  
  What is this?
  
  RRID:AB_627865
Visit annotations in context

Tags

RRID:AB_627865

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S266637912500326X
Apr 2025
www.sciencedirect.com www.sciencedirect.com

Oncogenic KRAS Addiction States Differentially Influence MTH1 Expression and 8-oxodGTPase Activity in Lung Adenocarcinoma

1
1. scibot 01 Apr 2025
  
  in Public
  
  RRID:AB_627865
  
  DOI: 10.1016/j.redox.2025.103610
  
  Resource: (Santa Cruz Biotechnology Cat# sc-30, RRID:AB_627865)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_627865
  
  What is this?
  
  RRID:AB_627865
Visit annotations in context

Tags

RRID:AB_627865

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2213231725001235
Nov 2024
www.sciencedirect.com www.sciencedirect.com

USP7 deubiquitinates KRAS and promotes non-small cell lung cancer

1
1. scibot 14 Nov 2024
  
  in Public
  
  RRID:AB_627865
  
  DOI: 10.1016/j.celrep.2024.114917
  
  Resource: (Santa Cruz Biotechnology Cat# sc-30, RRID:AB_627865)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_627865
  
  What is this?
  
  RRID:AB_627865
Visit annotations in context

Tags

RRID:AB_627865

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124724012683
May 2024
www.cell.com www.cell.com

Discovery of SOCS7 as a versatile E3 ligase for protein-based degraders

1
1. scibot 10 May 2024
  
  in Public
  
  RRID:AB_627865
  
  DOI: 10.1016/j.isci.2024.109802
  
  Resource: (Santa Cruz Biotechnology Cat# sc-30, RRID:AB_627865)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_627865
  
  What is this?
  
  RRID:AB_627865
Visit annotations in context

Tags

RRID:AB_627865

Annotators

scibot

URL

cell.com/iscience/abstract/S2589-0042(24)01024-1
Jun 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

DAB2IP Is a Bifunctional Tumor Suppressor That Regulates Wild-Type RAS and Inflammatory Cascades in KRAS Mutant Colon Cancer

1
1. scibot 07 Jun 2023
  
  in Public
  
  RRID:AB_627865
  
  DOI: 10.1158/0008-5472.CAN-22-0370
  
  Resource: (Santa Cruz Biotechnology Cat# sc-30, RRID:AB_627865)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_627865
  
  What is this?
  
  RRID:AB_627865
Visit annotations in context

Tags

RRID:AB_627865

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10236151/
May 2023
onlinelibrary.wiley.com onlinelibrary.wiley.com

Snail acetylation by autophagy-derived acetyl-coenzyme A promotes invasion and metastasis of KRAS-LKB1 co-mutated lung cancer cells

1
1. scibot 05 May 2023
  
  in Public
  
  RRID:AB_627865
  
  DOI: 10.1002/cac2.12332
  
  Resource: (Santa Cruz Biotechnology Cat# sc-30, RRID:AB_627865)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_627865
  
  What is this?
  
  RRID:AB_627865
Visit annotations in context

Tags

RRID:AB_627865

Annotators

scibot

URL

onlinelibrary.wiley.com/doi/10.1002/cac2.12332
Apr 2023
link.springer.com link.springer.com

Statins enhances antitumor effect of oxaliplatin in KRAS-mutated colorectal cancer cells and inhibits oxaliplatin-induced neuropathy

1
1. scibot 18 Apr 2023
  
  in Public
  
  RRID:AB_627865
  
  DOI: 10.1186/s12935-023-02884-z
  
  Resource: (Santa Cruz Biotechnology Cat# sc-30, RRID:AB_627865)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_627865
  
  What is this?
  
  RRID:AB_627865
Visit annotations in context

Tags

RRID:AB_627865

Annotators

scibot

URL

link.springer.com/article/10.1186/s12935-023-02884-z
Nov 2022
www.sciencedirect.com www.sciencedirect.com

NF1 loss of function as an alternative initiating event in pancreatic ductal adenocarcinoma

1
1. scibot 09 Nov 2022
  
  in Public
  
  RRID:AB_627865
  
  DOI: 10.1016/j.celrep.2022.111623
  
  Resource: (Santa Cruz Biotechnology Cat# sc-30, RRID:AB_627865)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_627865
  
  What is this?
  
  RRID:AB_627865
Visit annotations in context

Tags

RRID:AB_627865

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124722014942
Feb 2022
www.tandfonline.com www.tandfonline.com

GTP-binding protein Di-RAS3 diminishes the migration and invasion of non-small cell lung cancer by inhibiting the RAS/extracellular-regulated kinase pathway

1
1. scibot 21 Feb 2022
  
  in Public
  
  RRID:AB_627865
  
  DOI: 10.1080/21655979.2022.2031671
  
  Resource: (Santa Cruz Biotechnology Cat# sc-30, RRID:AB_627865)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_627865
  
  What is this?
  
  RRID:AB_627865
Visit annotations in context

Tags

RRID:AB_627865

Annotators

scibot

URL

tandfonline.com/doi/abs/10.1080/21655979.2022.2031671
Sep 2021
www.sciencedirect.com www.sciencedirect.com

NSD2 dimethylation at H3K36 promotes lung adenocarcinoma pathogenesis

1
1. scibot 23 Sep 2021
  
  in Public
  
  sc-30
  
  DOI: 10.1016/j.molcel.2021.08.034
  
  Resource: (Santa Cruz Biotechnology Cat# sc-30, RRID:AB_627865)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_627865
  
  What is this?
  
  RRID:AB_627865 RRIDCUR:Missing
Visit annotations in context

Tags

RRIDCUR:Missing

RRID:AB_627865

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276521007140
Jul 2021
mcr.aacrjournals.org mcr.aacrjournals.org

KRAS activation in gastric adenocarcinoma stimulates epithelial-to-mesenchymal transition to cancer stem-like cells and promotes metastasis

1
1. scibot 30 Jul 2021
  
  in Public
  
  KRAS
  
  DOI: 10.1158/1541-7786.MCR-19-0077
  
  Resource: (Santa Cruz Biotechnology Cat# sc-30, RRID:AB_627865)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_627865
  
  What is this?
  
  RRID:AB_627865 RRIDCUR:Missing
Visit annotations in context

Tags

RRIDCUR:Missing

RRID:AB_627865

Annotators

scibot

URL

mcr.aacrjournals.org/content/17/9/1945
www.sciencedirect.com www.sciencedirect.com

Oncogenic KRAS Regulates Amino Acid Homeostasis and Asparagine Biosynthesis via ATF4 and Alters Sensitivity to L-Asparaginase

1
1. scibot 27 Jul 2021
  
  in Public
  
  RRID:AB_62765
  
  DOI: 10.1016/j.ccell.2017.12.003
  
  Resource: (Santa Cruz Biotechnology Cat# sc-30, RRID:AB_627865)
  
  Curator: @evieth
  
  SciCrunch record: RRID:AB_627865
  
  Curator comments: Santa Cruz Biotechnology Cat# sc-30,
  
  What is this?
  
  RRIDCUR:Unresolved RRID:AB_627865 RRIDCUR:Incorrect
Visit annotations in context

Tags

RRID:AB_627865

RRIDCUR:Incorrect

RRIDCUR:Unresolved

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S153561081730555X
Apr 2021
www.sciencedirect.com www.sciencedirect.com

Cancer cells escape autophagy inhibition via NRF2-induced macropinocytosis

1
1. scibot 22 Apr 2021
  
  in Public
  
  RRID:AB_627865
  
  DOI: 10.1016/j.ccell.2021.02.016
  
  Resource: (Santa Cruz Biotechnology Cat# sc-30, RRID:AB_627865)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_627865
  
  What is this?
  
  RRID:AB_627865
Visit annotations in context

Tags

RRID:AB_627865

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1535610821001185
www.sciencedirect.com www.sciencedirect.com

Kinase-mediated RAS signaling via membraneless cytoplasmic protein granules

1
1. scibot 13 Apr 2021
  
  in Public
  
  RRID:AB_627865
  
  DOI: 10.1016/j.cell.2021.03.031
  
  Resource: (Santa Cruz Biotechnology Cat# sc-30, RRID:AB_627865)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_627865
  
  What is this?
  
  RRIDCUR:Validated RRID:AB_627865
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_627865

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0092867421003627
Nov 2020
www.sciencedirect.com www.sciencedirect.com

Overcoming Adaptive Resistance to KRAS and MEK Inhibitors by Co-targeting mTORC1/2 Complexes in Pancreatic Cancer

1
1. scibot 24 Nov 2020
  
  in Public
  
  RRID:AB_627865
  
  DOI: 10.1016/j.xcrm.2020.100131
  
  Resource: (Santa Cruz Biotechnology Cat# sc-30, RRID:AB_627865)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_627865
  
  What is this?
  
  RRID:AB_627865 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_627865

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2666379120301737
Sep 2020
www.sciencedirect.com www.sciencedirect.com

WAPL-Dependent Repair of Damaged DNA Replication Forks Underlies Oncogene-Induced Loss of Sister Chromatid Cohesion

1
1. scibot 07 Sep 2020
  
  in Public
  
  RRID:AB_627865
  
  DOI: 10.1016/j.devcel.2020.01.024
  
  Resource: (Santa Cruz Biotechnology Cat# sc-30, RRID:AB_627865)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_627865
  
  What is this?
  
  RRIDCUR:Validated RRID:AB_627865
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_627865

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1534580720300563
www.sciencedirect.com www.sciencedirect.com

Defining and Targeting Adaptations to Oncogenic KRASG12C Inhibition Using Quantitative Temporal Proteomics

1
1. scibot 04 Sep 2020
  
  in Public
  
  AB_627865
  
  DOI: 10.1016/j.celrep.2020.03.021
  
  Resource: (Santa Cruz Biotechnology Cat# sc-30, RRID:AB_627865)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_627865
  
  What is this?
  
  RRIDCUR:Validated RRID:AB_627865
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_627865

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124720303284
Jan 2020
www.sciencedirect.com www.sciencedirect.com

EGFR-Pak Signaling Selectively Regulates Glutamine Deprivation-Induced Macropinocytosis

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_627865
  
  DOI: 10.1016/j.devcel.2019.05.043
  
  Resource: (Santa Cruz Biotechnology Cat# sc-30, RRID:AB_627865)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_627865
  
  What is this?
  
  RRID:AB_627865 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_627865

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S153458071930485X
Nov 2018
www.sciencedirect.com www.sciencedirect.com

Chemistry-First Approach for Nomination of Personalized Treatment in Lung Cancer

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:AB_627865
  
  Resource used:
  
  (Santa Cruz Biotechnology Cat# sc-30, RRID:AB_627865)
  
  SciCrunch record: RRID:AB_627865
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_627865
Visit annotations in context

Tags

RRID:AB_627865

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0092867418303088
www.sciencedirect.com www.sciencedirect.com

KRAS Dimerization Impacts MEK Inhibitor Sensitivity and Oncogenic Activity of Mutant KRAS

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:AB_627865
  
  Resource used:
  
  (Santa Cruz Biotechnology Cat# sc-30, RRID:AB_627865)
  
  SciCrunch record: RRID:AB_627865
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_627865
Visit annotations in context

Tags

RRID:AB_627865

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0092867417315003
Nov 2017
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling

1
1. scibot 08 Nov 2017
  
  in Public
  
  RRID:AB_627865
  
  Resource used:
  
  (Santa Cruz Biotechnology Cat# sc-30, RRID:AB_627865)
  
  SciCrunch record: RRID:AB_627865
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_627865
Visit annotations in context

Tags

RRID:AB_627865

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC5279869/
www.sciencedirect.com www.sciencedirect.com

RasGRP3 Mediates MAPK Pathway Activation in GNAQ Mutant Uveal Melanoma

1
1. scibot 08 Nov 2017
  
  in Public
  
  AB_627865
  
  Curator: @gabimpine
  
  Resource used:
  
  (Santa Cruz Biotechnology Cat# sc-30, RRID:AB_627865)
  
  SciCrunch record: RRID:AB_627865
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_627865 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_627865

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1535610817301575
www.sciencedirect.com www.sciencedirect.com

Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling

1
1. scibot 08 Nov 2017
  
  in Public
  
  AB_627865
  
  Resource used:
  
  (Santa Cruz Biotechnology Cat# sc-30, RRID:AB_627865)
  
  SciCrunch record: RRID:AB_627865
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_627865
Visit annotations in context

Tags

RRID:AB_627865

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2405471216304082
www.sciencedirect.com www.sciencedirect.com

Mutant KRAS Enhances Tumor Cell Fitness by Upregulating Stress Granules

1
1. scibot 08 Nov 2017
  
  in Public
  
  AB_627865
  
  Curator: @Jmenke
  
  Resource used:
  
  (Santa Cruz Biotechnology Cat# sc-30, RRID:AB_627865)
  
  SciCrunch record: RRID:AB_627865
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_627865 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_627865

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0092867416316075