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  1. Last 7 days
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    Anticancer activity of RAS-GTP inhibition in cholangiocarcinoma
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    sciencedirect.com/science/article/pii/S1535610826001741
  3. Oct 2025
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    Nuclear hormone-sensitive lipase regulates adipose tissue mass and adipocyte metabolism
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    sciencedirect.com/science/article/pii/S1550413125004334
  5. Feb 2025
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    SMAD4 and KRAS Status Shape Cancer Cell-Stromal Crosstalk and Therapeutic Response in Pancreatic Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC7617379/
  7. Jan 2025
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    DYRK1A-TGF-β signaling axis determines sensitivity to OXPHOS inhibition in hepatocellular carcinoma
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    sciencedirect.com/science/article/pii/S1534580724007755
  9. May 2024
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    SMAD4 and KRAS status shape malignant-stromal crosstalk in pancreatic cancer
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    biorxiv.org/content/10.1101/2024.04.28.591518v1
  11. Mar 2024
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    Cytosolic pH is a direct nexus in linking environmental cues with insulin processing and secretion in pancreatic β cells
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  13. Feb 2024
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    EZH2/G9a interact to mediate drug resistance in non-small-cell lung cancer by regulating the SMAD4/ERK/c-Myc signaling axis
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    sciencedirect.com/science/article/pii/S2211124724000421
  15. Dec 2023
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    Smad4 sequestered in SFPQ condensates prevents TGF-β tumor-suppressive signaling
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    sciencedirect.com/science/article/pii/S1534580723006184
  17. Oct 2023
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    Tumorigenic effects of human mesenchymal stromal cells and fibroblasts on bladder cancer cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10534007/
  19. Sep 2023
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    ESRRB inhibits the TGF-β signaling pathway to drive cell proliferation in cervical cancer
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  21. Jul 2023
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  23. Apr 2023
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    Mitoxantrone and Mitoxantrone-Loaded Iron Oxide Nanoparticles Induce Cell Death in Human Pancreatic Ductal Adenocarcinoma Cell Spheroids
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    ncbi.nlm.nih.gov/pmc/articles/PMC10096321/
  25. Jan 2023
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    The loss of epithelial Smad4 drives immune evasion via CXCL1 while displaying vulnerability to combinatorial immunotherapy in gastric cancer
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    sciencedirect.com/science/article/pii/S2211124722017740
  27. Apr 2022
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    PGC1α-Mediated Metabolic Reprogramming Drives the Stemness of Pancreatic Precursor Lesions
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    ncbi.nlm.nih.gov/pmc/articles/PMC8709878/
  29. Feb 2022
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    Drug screening and genome editing in human pancreatic cancer organoids identifies drug-gene interactions and candidates for off-label therapy
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    sciencedirect.com/science/article/pii/S2666979X2200012X
  31. Jan 2022
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    Disruption of pancreatic stellate cell myofibroblast phenotype promotes pancreatic tumor invasion
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  33. Aug 2021
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    Cellular Barcoding Identifies Clonal Substitution as a Hallmark of Local Recurrence in a Surgical Model of Head and Neck Squamous Cell Carcinoma
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    sciencedirect.com/science/article/pii/S2211124718316942
  36. Jul 2021
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    Cellular Barcoding Identifies Clonal Substitution as a Hallmark of Local Recurrence in a Surgical Model of Head and Neck Squamous Cell Carcinoma
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    cell.com/developmental-cell/abstract/S1534-5807(17)30871-7
  39. Jan 2021
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    Mutations in SKI in Shprintzen–Goldberg syndrome lead to attenuated TGF-β responses through SKI stabilization
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    ncbi.nlm.nih.gov/pmc/articles/PMC7834018/
  41. Sep 2020
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    Febrile Temperature Critically Controls the Differentiation and Pathogenicity of T Helper 17 Cells
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    sciencedirect.com/science/article/pii/S1074761320300339
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    The testis protein ZNF165 is a SMAD3 cofactor that coordinates oncogenic TGFβ signaling in triple-negative breast cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC7302877/
  44. Jan 2020
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    Pterostilbene prevents hepatocyte epithelial‐mesenchymal transition in fructose‐induced liver fibrosis through suppressing miR‐34a/Sirt1/p53 and TGF‐β1/Smads signalling
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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.14573
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    Combined Inhibition of DYRK1A, SMAD, and Trithorax Pathways Synergizes to Induce Robust Replication in Adult Human Beta Cells
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    sciencedirect.com/science/article/pii/S1550413118307423
  47. Nov 2018
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    Twist1 Activation in Muscle Progenitor Cells Causes Muscle Loss Akin to Cancer Cachexia
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    sciencedirect.com/science/article/pii/S1534580718304192
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    Systematic Functional Annotation of Somatic Mutations in Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC5926201/
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    Resolving the Combinatorial Complexity of Smad Protein Complex Formation and Its Link to Gene Expression
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    sciencedirect.com/science/article/pii/S2405471217305380
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    Tumor-Suppressor Inactivation of GDF11 Occurs by Precursor Sequestration in Triple-Negative Breast Cancer
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    sciencedirect.com/science/article/pii/S1534580717308717
  52. Nov 2017
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    Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling
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    ncbi.nlm.nih.gov/pmc/articles/PMC5279869/
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    PPARγ Links BMP2 and TGFβ1 Pathways in Vascular Smooth Muscle Cells, Regulating Cell Proliferation and Glucose Metabolism
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    sciencedirect.com/science/article/pii/S1550413117301638
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    Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling
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    sciencedirect.com/science/article/pii/S2405471216304082