93 Matching Annotations
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    Protective effect of fisetin alone and in combination with lactobacillus using experimental model of diabetes associated cognitive impairment in rats
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    link.springer.com/article/10.1007/s11011-025-01722-7
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    IFNγ-mediated suppression of alternative NF-κB in tumor-resident myeloid cells promotes selective recruitment of cytotoxic but not regulatory T cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12546131/
  4. Oct 2025
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    Limited activation interdependence and differing patterns of the in vivo effects of IKK1 and IKK2 downstream of NIK
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    sciencedirect.com/science/article/pii/S2211124725011751
  6. Jul 2025
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    Formyl peptide receptor 2 (FPR2) mediates cisplatin-induced cochlear inflammation and hair cell apoptosis
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    sciencedirect.com/science/article/pii/S0300483X2500188X
  8. Jun 2025
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    Table 1 Resource table.
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    nature.com/articles/s41418-025-01517-4/tables/1
  11. May 2025
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    GADD45G operates as a pathological sensor orchestrating reactive gliosis and neurodegeneration
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    sciencedirect.com/science/article/pii/S0896627325003459
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    Positive impact of indicaxanthin from Opuntia ficus-indica fruit on high-fat diet–induced neuronal damage and gut microbiota dysbiosis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12094550/
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    Microglial depletion prevents visual deficits and retinal ganglion cell loss induced by early life stress in adult animals
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    pmc.ncbi.nlm.nih.gov/articles/PMC12085643/
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    Pre-existing epigenetic state and differential NF-κB activation shape type 2 immune cell responses
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    KMT2C deficiency drives transdifferentiation of double-negative prostate cancer and confer resistance to AR-targeted therapy
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    sciencedirect.com/science/article/pii/S1535610825001394
  17. Apr 2025
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    Tobacco smoke exposure is a driver of altered oxidative stress response and immunity in head and neck cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11971752/
  19. Mar 2025
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    The transcription factor MEF2C restrains microglial overactivation by inhibiting kinase CDK2
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    sciencedirect.com/science/article/pii/S1074761325000937
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    T-bet+ CXCR3+ B cells drive hyperreactive B-T cell interactions in multiple sclerosis
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  22. Feb 2025
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    ERK inhibits osteoclast differentiation in RAW 264.7 cells through the osteoprotegerin-mediated autophagy
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    sciencedirect.com/science/article/pii/S8756328225000365
  25. Nov 2024
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Prolactin protects hippocampal neurons against H2O2-induced neurotoxicity by suppressing BAX and NOX4 via the NF-κB signaling pathway
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    pmc.ncbi.nlm.nih.gov/articles/PMC11537405/
  27. Aug 2024
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    Inhibition of bromodomain and extra-terminal proteins targets constitutively active NFκB and STAT signaling in lymphoma and influences the expression of the antiapoptotic proteins BCL2A1 and c-MYC
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    Histone chaperone HIRA, promyelocytic leukemia protein, and p62/SQSTM1 coordinate to regulate inflammation during cell senescence
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    sciencedirect.com/science/article/pii/S1097276524006609
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    Gamma-glutamyl transferase 5 overexpression in cerebrovascular endothelial cells improves brain pathology, cognition, and behavior in APP/PS1 mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC11317949/
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    SIRT1 improves lactate homeostasis in the brain to alleviate parkinsonism via deacetylation and inhibition of PKM2
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  32. Jun 2024
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    Tumour microenvironment programming by an RNA–RNA-binding protein complex creates a druggable vulnerability in IDH-wild-type glioblastoma
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  34. May 2024
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    Epithelial-to-mesenchymal transition and NF-kB pathways are promoted by a mutant form of DDB2, unable to bind PCNA, in UV-damaged human cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC11110260/
  36. Apr 2024
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    Association of DNA methylation/demethylation with the functional outcome of stroke in a hyperinflammatory state
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  38. Mar 2024
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    Mecp2 knock-out astrocytes affect synaptogenesis by Interleukin 6 dependent mechanisms
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  40. Dec 2023
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Vasoinhibin apoptotic, inflammatory, and fibrinolytic actions are in a motif different from its antiangiogenic HGR motif
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    ncbi.nlm.nih.gov/pmc/articles/PMC10748576/
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    Anti-TLR4 biological response to titanium nitride-coated dental implants: anti-inflammatory response and extracellular matrix synthesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10728300/
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    Platelet-activating factor and protease-activated receptor 2 cooperate to promote neutrophil recruitment and lung inflammation through nuclear factor-kappa B transactivation
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  44. Nov 2023
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    Targeting GPR65 alleviates hepatic inflammation and fibrosis by suppressing the JNK and NF-κB pathways
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    ncbi.nlm.nih.gov/pmc/articles/PMC10675918/
  46. Sep 2023
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    circELMOD3 increases and stabilizes TRIM13 by sponging miR-6864-5p and direct binding to inhibit HCC progression
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    CGK733 alleviates ovariectomy-induced bone loss through blocking RANKL-mediated Ca2+ oscillations and NF-κB/MAPK signaling pathways
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  49. Aug 2023
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    The apoptotic, inflammatory, and fibrinolytic actions of vasoinhibin are in a motif different from its antiangiogenic HGR motif
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    biorxiv.org/content/10.1101/2023.08.18.553934v1
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    Serotonin receptor subtype-2B signaling is associated with interleukin-18-induced cardiomyoblast hypertrophy in vitro
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  52. Jun 2023
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  54. Dec 2022
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    Blockage of Lamin-A/C loss diminishes the pro-inflammatory macrophage response
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  56. Aug 2022
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    Muscone and (+)-Borneol Cooperatively Strengthen CREB Induction of Claudin 5 in IL-1 β-Induced Endothelium Injury
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    ncbi.nlm.nih.gov/pmc/articles/PMC9394259/
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    APOE4 drives inflammation in human astrocytes via TAGLN3 repression and NF-κB activation
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    sciencedirect.com/science/article/pii/S2211124722010178
  59. Jun 2022
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    cGAS and DDX41-STING mediated intrinsic immunity spreads intercellularly to promote neuroinflammation in SOD1 ALS model
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    Undercarboxylated, but not Carboxylated, Osteocalcin suppresses TNF-α induced inflammatory signaling pathway in Myoblast
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    ncbi.nlm.nih.gov/pmc/articles/PMC9188654/
  62. Apr 2022
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    Secreted NF-κB suppressive microbial metabolites modulate gut inflammation
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  64. Mar 2022
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    Cerebrospinal fluid of progressive multiple sclerosis patients reduces differentiation and immune functions of oligodendrocyte progenitor cells
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    onlinelibrary.wiley.com/doi/10.1002/glia.24165
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  67. Feb 2022
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    CASCADE: high-throughput characterization of regulatory complex binding altered by non-coding variants
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  69. Dec 2021
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    Monosialoganglioside (GM1) Attenuates Spinal Cord Injury-Induced Inflammation by Inhibiting TLR4/NF-κB Pathway
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    link.springer.com/article/10.1134/S181971242102015X
  71. Nov 2021
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    HNRNPA2B1 as a trigger of RNA switch modulates the miRNA-mediated regulation of CDK6
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    sciencedirect.com/science/article/pii/S2589004221013146
  73. Aug 2021
  74. www.physiology.org www.physiology.org
    Activated cholangiocytes release macrophage-polarizing extracellular vesicles bearing the DAMP S100A11
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    physiology.org/doi/abs/10.1152/ajpcell.00250.2019
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  77. Jul 2021
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    Mitochondria-Derived Vesicles Deliver Antimicrobial Reactive Oxygen Species to Control Phagosome-Localized Staphylococcus aureus
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    Targeting Excessive EZH1 and EZH2 Activities for Abnormal Histone Methylation and Transcription Network in Malignant Lymphomas
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    PI3K inhibitors protect against glucocorticoid-induced skin atrophy
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    PIAS1 Regulates Mutant Huntingtin Accumulation and Huntington’s Disease-Associated Phenotypes In Vivo
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  84. Jun 2021
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  86. May 2021
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    Inhibition of miR-155 potentially protects Lipopolysaccharide-induced acute lung injury through the IRF2BP2-NFAT1 pathway
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    journals.physiology.org/doi/abs/10.1152/ajpcell.00116.2020
  88. Apr 2021
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    Distinct Foxp3 enhancer elements coordinate development, maintenance, and function of regulatory T cells
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    Discovery of Protein-Protein Interaction Inhibitors by Integrating Protein Engineering and Chemical Screening Platforms
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    Co-condensation between transcription factor and coactivator p300 modulates transcriptional bursting kinetics
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    Influence of the microenvironment on modulation of the host response by typhoid toxin
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  93. Dec 2020
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  95. Sep 2020
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    The Autophagy-Initiating Kinase ULK1 Controls RIPK1-Mediated Cell Death
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    Deamidation Shunts RelA from Mediating Inflammation to Aerobic Glycolysis
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    TLR4-Mediated Pathway Triggers Interferon-Independent G0 Arrest and Antiviral SAMHD1 Activity in Macrophages
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    SPHK2-Generated S1P in CD11b+ Macrophages Blocks STING to Suppress the Inflammatory Function of Alveolar Macrophages
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    The Cytokine IL-17A Limits Th17 Pathogenicity via a Negative Feedback Loop Driven by Autocrine Induction of IL-24
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    ncbi.nlm.nih.gov/pmc/articles/PMC7362799/
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    Obesity induces preadipocyte CD36 expression promoting inflammation via the disruption of lysosomal calcium homeostasis and lysosome function
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    Altered Adhesion and Migration of Human Mesenchymal Stromal Cells under Febrile Temperature Stress Involves NF-κβ Pathway
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    nature.com/articles/s41598-020-61361-z
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    NF-κB Dynamics Discriminate between TNF Doses in Single Cells
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    cell.com/cell-systems/abstract/S2405-4712(17)30448-9
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    Sodium butyrate inhibits high cholesterol-induced neuronal amyloidogenesis by modulating NRF2 stabilization-mediated ROS levels: involvement of NOX2 and SOD1
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    ncbi.nlm.nih.gov/pmc/articles/PMC7303181/
  106. Jan 2020
  107. www.sciencedirect.com www.sciencedirect.com
    Targeting Spt5-Pol II by Small-Molecule Inhibitors Uncouples Distinct Activities and Reveals Additional Regulatory Roles
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    Parkin in early stage LPS-stimulated BV-2 cells regulates pro-inflammatory response and mitochondrial quality via mitophagy
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    Androgen receptor activation reduces the endothelial cell proliferation through activating the cSrc/AKT/p38/ERK/NFκB-mediated pathway
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    sciencedirect.com/science/article/pii/S0960076019302869
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    Mitochondrial Damage Causes Inflammation via cGAS-STING Signaling in Acute Kidney Injury
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    cell.com/cell-reports/fulltext/S2211-1247(19)31238-0
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    The Ubiquitin-Editing Enzyme A20 Regulates Synapse Remodeling and Efficacy
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    An osteoclastogenesis system, the RANKL/RANK signalling pathway, contributes to aggravated allergic inflammation
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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.14615
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  114. Nov 2018
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    Increased Lactate Secretion by Cancer Cells Sustains Non-cell-autonomous Adaptive Resistance to MET and EGFR Targeted Therapies
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    Th17 Lymphocytes Induce Neuronal Cell Death in a Human iPSC-Based Model of Parkinson’s Disease
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    IDH2 Deficiency in Microglia Decreases the Pro-inflammatory Response <Emphasis Type="Italic">via</Emphasis> the ERK and NF-κB Pathways
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    link.springer.com/article/10.1007/s10753-018-0840-5
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    A constitutively-active IKK-complex at the axon initial segment
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  120. Nov 2017
  121. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Ulinastatin Inhibited Sepsis‐induced Spinal Inflammation to Alleviate Peripheral Neuromuscular Dysfunction in an Experimental Rat Model of Neuromyopathy
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14145/full
  122. www.sciencedirect.com www.sciencedirect.com
    MLKL, the Protein that Mediates Necroptosis, Also Regulates Endosomal Trafficking and Extracellular Vesicle Generation
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    sciencedirect.com/science/article/pii/S1074761317302285
  123. www.sciencedirect.com www.sciencedirect.com
    Time-lapse imaging of p65 and IκBα translocation kinetics following Ca2 +-induced neuronal injury reveals biphasic translocation kinetics in surviving neurons
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    sciencedirect.com/science/article/pii/S1044743116300987
  124. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NF-κB regulates neuronal ankyrin-G via a negative feedback loop
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    ncbi.nlm.nih.gov/pmc/articles/PMC5299403/
  125. www.sciencedirect.com www.sciencedirect.com
    PIAS1 Regulates Mutant Huntingtin Accumulation and Huntington’s Disease-Associated Phenotypes In Vivo
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    sciencedirect.com/science/article/pii/S0896627316300058
  126. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    ncbi.nlm.nih.gov/pmc/articles/PMC4380931/
  127. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Systematic analysis of BRAFV600E melanomas reveals a role for JNK/c-Jun pathway in adaptive resistance to drug-induced apoptosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC4380931/