85 Matching Annotations
  1. Feb 2025
  2. www.sciencedirect.com www.sciencedirect.com
    Unraveling AURKB as a potential therapeutic target in pulmonary hypertension using integrated transcriptomic analysis and pre-clinical studies
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    sciencedirect.com/science/article/pii/S2666379125000370
  3. 52.53.155.43 52.53.155.43
    A non-catalytic function for Rad18 in sustaining glioblastoma proliferation
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    1. scibot 06 Feb 2025
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  4. Jan 2025
  5. www.sciencedirect.com www.sciencedirect.com
    Exosomal miR-302b rejuvenates aging mice by reversing the proliferative arrest of senescent cells
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    sciencedirect.com/science/article/pii/S1550413124004819
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    Targeting N-Myc in neuroblastoma with selective Aurora kinase A degraders
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    1. scibot 09 Jan 2025
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    sciencedirect.com/science/article/pii/S2451945624005166
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    Age-associated interplay between zinc deficiency and Golgi stress hinders microtubule-dependent cellular signaling and epigenetic control
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    1. scibot 07 Jan 2025
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    sciencedirect.com/science/article/pii/S1534580724007639
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    Revealing the role of cancer-associated fibroblast senescence in prognosis and immune landscape in pancreatic cancer
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    1. scibot 03 Jan 2025
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      DOI: 10.1016/j.isci.2024.111612

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    sciencedirect.com/science/article/pii/S2589004224028396
  9. Dec 2024
  10. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Fingolimod Inhibits C6 Rat Glioma Proliferation and Migration, Induces Sub-G1 Cell Cycle Arrest, Mitochondrial and Extrinsic Apoptosis In Vitro and Reduces Tumour Growth In Vivo
    1
    1. scibot 13 Dec 2024
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      DOI: 10.1111/1440-1681.70012

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    onlinelibrary.wiley.com/doi/10.1111/1440-1681.70012
  11. www.sciencedirect.com www.sciencedirect.com
    Morphogenesis and regeneration share a conserved core transition cell state program that controls lung epithelial cell fate
    1
    1. scibot 12 Dec 2024
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    sciencedirect.com/science/article/pii/S1534580724006993
  12. Nov 2024
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Greater TIMP‐1 protein levels and neointimal formation represent sex‐dependent cellular events limiting aortic vessel expansion in female rats
    1
    1. scibot 26 Nov 2024
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      DOI: 10.1002/iub.2916

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    pmc.ncbi.nlm.nih.gov/articles/PMC11580379/
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    p21 regulates expression of ECM components and promotes pulmonary fibrosis via CDK4 and Rb
    1
    1. scibot 21 Nov 2024
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      DOI: 10.1038/s44318-024-00246-7

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    pmc.ncbi.nlm.nih.gov/articles/PMC11574164/
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CEP192 localises mitotic Aurora-A activity by priming its interaction with TPX2
    1
    1. scibot 21 Nov 2024
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      DOI: 10.1038/s44318-024-00240-z

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    pmc.ncbi.nlm.nih.gov/articles/PMC11574021/
  16. Sep 2024
  17. www.sciencedirect.com www.sciencedirect.com
    The Role of MFN2 in Regulating Endothelial Cell Senescence: Implications for Vascular Aging
    1
    1. scibot 25 Sep 2024
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      DOI: 10.1016/j.isci.2024.110809

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    sciencedirect.com/science/article/pii/S2589004224020340
  18. Aug 2024
  19. www.sciencedirect.com www.sciencedirect.com
    On the role of p53 in the cellular response to aneuploidy
    1
    1. scibot 28 Aug 2024
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      DOI: 10.1016/j.celrep.2021.108892

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    sciencedirect.com/science/article/pii/S2211124721002060
  20. www.biorxiv.org www.biorxiv.org
    Senescent cell clearance ameliorates temporal lobe epilepsy and associated spatial memory deficits in mice
    1
    1. scibot 19 Aug 2024
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      DOI: 10.1101/2024.07.30.605784

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    biorxiv.org/content/10.1101/2024.07.30.605784v1
  21. Jul 2024
  22. www.cell.com www.cell.com
    Adaptation to an acid microenvironment promotes pancreatic cancer organoid growth and drug resistance
    1
    1. scibot 18 Jul 2024
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      DOI: 10.1016/j.celrep.2024.114409

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    cell.com/cell-reports/fulltext/S2211-1247(24)00738-1
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Dedicated Evolutionarily Conserved Molecular Network Licenses Differentiated Cells to Return to the Cell Cycle
    1
    1. scibot 16 Jul 2024
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      DOI: 10.1016/j.devcel.2020.07.005

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    ncbi.nlm.nih.gov/pmc/articles/PMC7606764/
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Renal inflammation combined with renal function reserve reduction accelerate kidney aging via pentose phosphate pathway
    1
    1. scibot 03 Jul 2024
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      DOI: 10.1016/j.isci.2024.110045

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    ncbi.nlm.nih.gov/pmc/articles/PMC11214290/
  25. Apr 2024
  26. www.sciencedirect.com www.sciencedirect.com
    TM7SF3 controls TEAD1 splicing to prevent MASH-induced liver fibrosis
    1
    1. scibot 26 Apr 2024
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      DOI: 10.1016/j.cmet.2024.04.003

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    sciencedirect.com/science/article/pii/S1550413124001232
  27. www.sciencedirect.com www.sciencedirect.com
    Alanyl-tRNA synthetase, AARS1, is a lactate sensor and lactyltransferase that lactylates p53 and contributes to tumorigenesis
    1
    1. scibot 23 Apr 2024
      RRID:AB_628073

      DOI: 10.1016/j.cell.2024.04.002

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    sciencedirect.com/science/article/pii/S0092867424003970
  28. Feb 2024
  29. aacrjournals.org aacrjournals.org
    Inhibition of PRL2 upregulates PTEN and attenuates tumor growth in Tp53-deficient sarcoma and lymphoma mouse models
    1
    1. scibot 27 Feb 2024
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      DOI: 10.1158/2767-9764.CRC-23-0308

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    aacrjournals.org/cancerrescommun/article/4/1/5/732220/Inhibition-of-PRL2-Upregulates-PTEN-and-Attenuates
  30. www.sciencedirect.com www.sciencedirect.com
    A synergistic two-drug therapy specifically targets a DNA repair dysregulation that occurs in p53-deficient colorectal and pancreatic cancers
    1
    1. scibot 22 Feb 2024
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      DOI: 10.1016/j.xcrm.2024.101434

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    sciencedirect.com/science/article/pii/S2666379124000570
  31. Jan 2024
  32. aacrjournals.org aacrjournals.org
    Inhibition of PRL2 upregulates PTEN and attenuates tumor growth in Tp53-deficient sarcoma and lymphoma mouse models
    1
    1. scibot 10 Jan 2024
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      DOI: 10.1158/2767-9764.CRC-23-0308

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    aacrjournals.org/cancerrescommun/article/4/1/5/732220/Inhibition-of-PRL2-Upregulates-PTEN-and-Attenuates
  33. Oct 2023
  34. www.sciencedirect.com www.sciencedirect.com
    A fluorophore-conjugated reagent enabling rapid detection, isolation and live tracking of senescent cells
    1
    1. scibot 13 Oct 2023
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      DOI: 10.1016/j.molcel.2023.09.006

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    sciencedirect.com/science/article/pii/S1097276523007037
  35. Sep 2023
  36. www.sciencedirect.com www.sciencedirect.com
    Defective uterine spiral artery remodelling and placental senescence in a pregnant rat model of polycystic ovary syndrome
    1
    1. scibot 08 Sep 2023
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      DOI: 10.1016/j.ajpath.2023.08.008

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    sciencedirect.com/science/article/pii/S0002944023003152
  37. Aug 2023
  38. 52.53.155.43 52.53.155.43
    Synergy of 5-aminolevulinate supplement and CX3CR1 suppression promotes liver regeneration via elevated IGF-1 signaling
    2
    1. scibot 18 Aug 2023
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      DOI: 10.1016/j.celrep.2023.112984

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    2. scibot 16 Aug 2023
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      DOI: 10.1016/j.celrep.2023.112984

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    52.53.155.43/1bbe45cf5b4e78c7829bbc8558904ff45b580eb3/PIIS2211124723009956-html.html
  39. www.sciencedirect.com www.sciencedirect.com
    CdGAP is a talin-binding protein and a target of TGF-β signaling that promotes HER2-positive breast cancer growth and metastasis
    1
    1. scibot 10 Aug 2023
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      DOI: 10.1016/j.celrep.2023.112936

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    sciencedirect.com/science/article/pii/S2211124723009476
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Kinase Suppressor of RAS 1 (KSR1) Maintains the Transformed Phenotype of BRAFV600E Mutant Human Melanoma Cells
    1
    1. scibot 01 Aug 2023
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      DOI: 10.3390/ijms241411821

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    ncbi.nlm.nih.gov/pmc/articles/PMC10380721/
  41. Jul 2023
  42. anatomypubs.onlinelibrary.wiley.com anatomypubs.onlinelibrary.wiley.com
    Patterns of senescence and apoptosis during development of branchial arches, epibranchial placodes, and pharyngeal pouches
    1
    1. scibot 05 Jul 2023
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      DOI: 10.1002/dvdy.637

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    anatomypubs.onlinelibrary.wiley.com/doi/10.1002/dvdy.637
  43. Jun 2023
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Uterine-specific Ezh2 deletion enhances stromal cell senescence and impairs placentation, resulting in pregnancy loss
    1
    1. scibot 24 Jun 2023
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      DOI: 10.1016/j.isci.2023.107028

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    ncbi.nlm.nih.gov/pmc/articles/PMC10285549/
  45. www.sciencedirect.com www.sciencedirect.com
    Rapid adaptation to CDK2 inhibition exposes intrinsic cell-cycle plasticity
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      DOI: 10.1016/j.cell.2023.05.013

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    sciencedirect.com/science/article/pii/S0092867423005329
  46. May 2023
  47. www.sciencedirect.com www.sciencedirect.com
    Differential cell-cycle control by oscillatory versus sustained Hes1 expression via p21
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      DOI: 10.1016/j.celrep.2023.112520

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    sciencedirect.com/science/article/pii/S2211124723005314
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synthetic miR-21 decoy circularized by tRNA splicing mechanism inhibited tumorigenesis in glioblastoma in vitro and in vivo models
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      DOI: 10.1016/j.omtn.2023.04.001

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    ncbi.nlm.nih.gov/pmc/articles/PMC10173299/
  49. www.sciencedirect.com www.sciencedirect.com
    p53-independent tumor suppression by cell-cycle arrest via CREB/ATF transcription factor OASIS
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      RRID:AB_628073

      DOI: 10.1016/j.celrep.2023.112479

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    sciencedirect.com/science/article/pii/S2211124723004904
  50. Feb 2023
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Senescence Rewires Microenvironment Sensing to Facilitate Antitumor Immunity
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    1. scibot 10 Feb 2023
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      DOI: 10.1158/2159-8290.CD-22-0528

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    ncbi.nlm.nih.gov/pmc/articles/PMC9901536/
  52. Nov 2022
  53. www.sciencedirect.com www.sciencedirect.com
    Biosensor Cell-Fit-HD4D for correlation of single-cell fate and microscale energy deposition in complex ion beams
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      DOI: 10.1016/j.xpro.2022.101798

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    sciencedirect.com/science/article/pii/S2666166722006785
  54. Sep 2022
  55. www.sciencedirect.com www.sciencedirect.com
    The CX3CL1 intracellular domain exhibits neuroprotection via insulin receptor/ insulin like growth factor receptor signaling
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      DOI: 10.1016/j.jbc.2022.102532

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    sciencedirect.com/science/article/pii/S0021925822009759
  56. www.sciencedirect.com www.sciencedirect.com
    Targeting the USP7/RRM2 axis drives senescence and sensitizes melanoma cells to HDAC/LSD1 inhibitors
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    1. scibot 21 Sep 2022
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      DOI: 10.1016/j.celrep.2022.111396

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    sciencedirect.com/science/article/pii/S2211124722012335
  57. Aug 2022
  58. www.sciencedirect.com www.sciencedirect.com
    Increasing cell size remodels the proteome and promotes senescence
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      DOI: 10.1016/j.molcel.2022.07.017

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      SciCrunch record: RRID:AB_628073

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      RRID:AB_628073 RRIDCUR:Validated
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    ncbi.nlm.nih.gov/pmc/articles/PMC5957528/
  114. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A polymorphism in the tumor suppressor p53 affects aging and longevity in mouse models
    1
    1. scibot 05 Nov 2018
      RRID:AB_628073

      Curator: @evieth

      Resource used:

      (Santa Cruz Biotechnology Cat# sc-6246, RRID:AB_628073)

      SciCrunch record: RRID:AB_628073

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:AB_628073 RRIDCUR:Validated
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    ncbi.nlm.nih.gov/pmc/articles/PMC5906094/
  115. www.sciencedirect.com www.sciencedirect.com
    Distinct Cell-Cycle Control in Two Different States of Mouse Pluripotency
    1
    1. scibot 05 Nov 2018
      RRID:AB_628073

      Curator: @evieth

      Resource used:

      (Santa Cruz Biotechnology Cat# sc-6246, RRID:AB_628073)

      SciCrunch record: RRID:AB_628073

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:AB_628073 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1934590917303715
  116. Nov 2017
  117. www.nature.com www.nature.com
    Ccdc3: A New P63 Target Involved in Regulation Of Liver Lipid Metabolism
    1
    1. scibot 08 Nov 2017
      mouse p21

      Curator: @kaitlinsung

      Resource used:

      (Santa Cruz Biotechnology Cat# sc-6246, RRID:AB_628073)

      SciCrunch record: RRID:AB_628073

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:AB_628073 RRIDCUR:Missing
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    nature.com/articles/s41598-017-09228-8
  118. www.sciencedirect.com www.sciencedirect.com
    Enhancer Reprogramming Promotes Pancreatic Cancer Metastasis
    1
    1. scibot 08 Nov 2017
      RRID:AB_628073

      Curator: @chewbeccax

      Resource used:

      (Santa Cruz Biotechnology Cat# sc-6246, RRID:AB_628073)

      SciCrunch record: RRID:AB_628073

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:AB_628073 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0092867417308140
  119. www.sciencedirect.com www.sciencedirect.com
    Chromosome Mis-segregation Generates Cell-Cycle-Arrested Cells with Complex Karyotypes that Are Eliminated by the Immune System
    1
    1. scibot 08 Nov 2017
      AB_628073

      Curator: @chewbeccax

      Resource used:

      (Santa Cruz Biotechnology Cat# sc-6246, RRID:AB_628073)

      SciCrunch record: RRID:AB_628073

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:AB_628073 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1534580717304306
  120. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Early Molecular Stratification of High-risk Primary Biliary Cholangitis
    1
    1. scibot 08 Nov 2017
      AB_628073

      Curator: @gabimpine

      Resource used:

      (Santa Cruz Biotechnology Cat# sc-6246, RRID:AB_628073)

      SciCrunch record: RRID:AB_628073

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:AB_628073 RRIDCUR:Validated
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    ncbi.nlm.nih.gov/pmc/articles/PMC5161439/