145 Matching Annotations
  1. Last 7 days
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    ADSL deficiency is a secondary mitochondrial disease affecting organelle homeostasis and ERK2/AKT signaling in a linear genotype-phenotype relation
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    sciencedirect.com/science/article/pii/S2211124725010010
  3. Aug 2025
  4. 52.53.155.43 52.53.155.43
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    NIPSNAP1 and NIPSNAP2 Act as “Eat Me” Signals for Mitophagy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12335005/
  6. Jul 2025
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    An updated inventory of genes essential for oxidative phosphorylation identifies a mitochondrial origin in familial Ménière’s disease
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    sciencedirect.com/science/article/pii/S221112472500840X
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  9. Jun 2025
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    Senolytic Treatment Attenuates Global Ischemic Brain Injury and Enhances Cognitive Recovery by Targeting Mitochondria
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    link.springer.com/article/10.1007/s10571-025-01580-y
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    Hepatic micropeptide modulates mitochondrial RNA processing machinery in hepatocellular carcinoma
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    sciencedirect.com/science/article/pii/S1097276525004666
  12. May 2025
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The mitophagy receptors BNIP3 and NIX mediate tight attachment and expansion of the isolation membrane to mitochondria
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    pmc.ncbi.nlm.nih.gov/articles/PMC12071194/
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    Heterogeneity of late endosome/lysosomes shown by multiplexed DNA-PAINT imaging
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  15. Apr 2025
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    The MFN2 Q367H variant reveals a novel pathomechanism connected to mtDNA-mediated inflammation
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    pmc.ncbi.nlm.nih.gov/articles/PMC11966011/
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    Xuebijing injection alleviates septic acute kidney injury by modulating inflammation, mitochondrial dysfunction, and endoplasmic reticulum stress
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  19. Mar 2025
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    PI3Kβ functions as a protein kinase to promote cellular protein O-GlcNAcylation and acetyl-CoA production for tumor growth
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    Ectopic protein lysine methacrylation contributes to defects caused by loss of HIBCH or ECHS1
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  22. Feb 2025
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    Compositionally unique mitochondria in filopodia support cellular migration
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    Copper Drives Remodeling of Metabolic State and Progression of Clear Cell Renal Cell Carcinoma
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    Rhodoquinone carries electrons in the mammalian electron transport chain
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    G3BP1 ribonucleoprotein complexes regulate focal adhesion protein mobility and cell migration
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    pmc.ncbi.nlm.nih.gov/articles/PMC11923778/
  27. Dec 2024
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Phosphorylation of Optineurin by protein kinase D regulates Parkin-dependent mitophagy
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  29. www.science.org www.science.org
    Specific tRNAs promote mRNA decay by recruiting the CCR4-NOT complex to translating ribosomes
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    Mitochondrial calcium uptake declines during aging and is directly activated by oleuropein to boost energy metabolism and skeletal muscle performance
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  31. Nov 2024
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Specific tRNAs promote mRNA decay by recruiting the CCR4-NOT complex to translating ribosomes
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  33. Oct 2024
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CALHM2 is a mitochondrial protein import channel that regulates fatty acid metabolism
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    Mitotic ER-mitochondria contact enhances mitochondrial Ca2+ influx to promote cell division
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  36. Aug 2024
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CLPB disaggregase dysfunction impacts the functional integrity of the proteolytic SPY complex
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  38. Jul 2024
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TP53INP2-dependent activation of muscle autophagy ameliorates sarcopenia and promotes healthy aging
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    The MFN2 Q367H variant from a patient with late-onset distal myopathy reveals a novel pathomechanism connected to mtDNA-mediated inflammation
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  42. Jun 2024
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    Teriflunomide/leflunomide synergize with chemotherapeutics by decreasing mitochondrial fragmentation via DRP1 in SCLC
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    MTFP1 controls mitochondrial fusion to regulate inner membrane quality control and maintain mtDNA levels
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    TRABD modulates mitochondrial homeostasis and tissue integrity
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  46. May 2024
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KAT8 compound inhibition inhibits the initial steps of PINK1-dependant mitophagy
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    ncbi.nlm.nih.gov/pmc/articles/PMC11111795/
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    Opportunistic pathogen Porphyromonas gingivalis targets the LC3B-ceramide complex and mediates lethal mitophagy resistance in oral tumors
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    ncbi.nlm.nih.gov/pmc/articles/PMC11108982/
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    TRIM37 is a primate-specific E3 ligase for Huntingtin and accounts for the striatal degeneration in Huntington’s disease
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    Mitochondrial respiratory function is preserved under cysteine starvation via glutathione catabolism in NSCLC
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    Acyl-CoA synthetase 4 modulates mitochondrial function in breast cancer cells
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  52. Apr 2024
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    Cross-link assisted spatial proteomics to map sub-organelle proteomes and membrane protein topologies
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    Osteopontin drives neuroinflammation and cell loss in MAPT-N279K frontotemporal dementia patient neurons
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  55. Mar 2024
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The RNA binding proteins LARP4A and LARP4B promote sarcoma and carcinoma growth and metastasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10963253/
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    A novel mechanism of PHB2-mediated mitophagy participating in the development of Parkinson's disease
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    Acetyl-CoA carboxylase obstructs CD8+ T cell lipid utilization in the tumor microenvironment
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  59. Feb 2024
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    NEMF-mediated Listerin-independent mitochondrial translational surveillance by E3 ligase Pirh2 and mitochondrial protease ClpXP
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  61. 52.53.155.43 52.53.155.43
    The iron chelator and OXPHOS inhibitor VLX600 induces mitophagy and an autophagy-dependent type of cell death in glioblastoma cells
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  62. journals.physiology.org journals.physiology.org
    The iron chelator and OXPHOS inhibitor VLX600 induces mitophagy and an autophagy-dependent type of cell death in glioblastoma cells
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    journals.physiology.org/doi/10.1152/ajpcell.00293.2023
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    The HRI branch of the integrated stress response selectively triggers mitophagy
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  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Characterization of a novel variant in the HR1 domain of MFN2 in a patient with ataxia, optic atrophy and sensorineural hearing loss
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    ncbi.nlm.nih.gov/pmc/articles/PMC10808857/
  65. Jan 2024
  66. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mitophagy promotes resistance to BH3 mimetics in acute myeloid leukemia
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  67. Nov 2023
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tamoxifen for the treatment of myeloproliferative neoplasms: A Phase II clinical trial and exploratory analysis
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  69. Oct 2023
  70. onlinelibrary.wiley.com onlinelibrary.wiley.com
    STAT3 modulates CD4+ T mitochondrial dynamics and function in aging
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    onlinelibrary.wiley.com/doi/10.1111/acel.13996
  71. Sep 2023
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Examining PI3K-signaling-dependent regulation of lens organelle free zone formation via immunolocalization and immunoblotting in chick embryos
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    ncbi.nlm.nih.gov/pmc/articles/PMC10509694/
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    Alterations of lipid-mediated mitophagy result in aging-dependent sensorimotor defects
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    onlinelibrary.wiley.com/doi/10.1111/acel.13954
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    Melatonin Prevents Non-image-Forming Visual System Alterations Induced by Experimental Glaucoma in Rats
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    link.springer.com/article/10.1007/s12035-021-02374-1
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    Brain-derived neurotrophic factor protects neurons by stimulating mitochondrial function through protein kinase A
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    Damaged mitochondria recruit the effector NEMO to activate NF-κB signaling
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  77. Aug 2023
  78. www.biorxiv.org www.biorxiv.org
    KAT8 compound inhibition inhibits PINK1/Parkin-dependent mitophagy and initiates mitochondrial delivery to lysosomes
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    biorxiv.org/content/10.1101/2023.08.03.551835v1
  79. Jul 2023
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    PGAM5 is an MFN2 phosphatase that plays an essential role in the regulation of mitochondrial dynamics
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    A Proximity Labeling Strategy Enables Proteomic Analysis of Inter-organelle Membrane Contacts
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  83. Jun 2023
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    A mitochondrial iron-responsive pathway regulated by DELE1
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    Excess pancreatic elastase alters acinar-β cell communication by impairing the mechano-signaling and the PAR2 pathways
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    An Epstein-Barr virus protein interaction map reveals NLRP3 inflammasome evasion via MAVS UFMylation
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    Endogenous PP2A inhibitor CIP2A degradation by chaperone-mediated autophagy contributes to the antitumor effect of mitochondrial complex I inhibition
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  88. May 2023
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    The ultrastructural function of MLN64 in the late endosome–mitochondria membrane contact sites in placental cells
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  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The First Transcriptomic Atlas of the Adult Lacrimal Gland Reveals Epithelial Complexity and Identifies Novel Progenitor Cells in Mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC10216974/
  91. Apr 2023
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    NAD depletion mediates cytotoxicity in human neurons with autophagy deficiency
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    Mitochondrial fragmentation and donut formation enhance mitochondrial secretion to promote osteogenesis
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    Optineurin provides a mitophagy contact site for TBK1 activation
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    biorxiv.org/content/10.1101/2023.02.24.529790v1
  95. Mar 2023
  96. www.cell.com www.cell.com
    TNIP1 inhibits selective autophagy via bipartite interaction with LC3/GABARAP and TAX1BP1
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    cell.com/molecular-cell/abstract/S1097-2765(23)00150-8
  97. Feb 2023
  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NRF3 activates mTORC1 arginine-dependently for cancer cell viability
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    ncbi.nlm.nih.gov/pmc/articles/PMC9932127/
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    Sigma-1 receptor maintains ATAD3A as a monomer to inhibit mitochondrial fragmentation at the mitochondria-associated membrane in amyotrophic lateral sclerosis
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  100. Jan 2023
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    VAP-A intrinsically disordered regions enable versatile tethering at membrane contact sites
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  102. Dec 2022
  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An ER phospholipid hydrolase drives ER-associated mitochondrial constriction for fission and fusion
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    ncbi.nlm.nih.gov/pmc/articles/PMC9725753/
  104. Nov 2022
  105. www.embopress.org www.embopress.org
    LUBAC assembles a ubiquitin signaling platform at mitochondria for signal amplification and transport of NF-κB to the nucleus
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    embopress.org/doi/10.15252/embj.2022112006
  106. academic.oup.com academic.oup.com
    Regulation of mitophagy by the NSL complex underlies genetic risk for Parkinson’s disease at 16q11.2 and MAPT H1 loci
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    academic.oup.com/brain/advance-article/doi/10.1093/brain/awac325/6694190
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    Tissue imaging reveals disruption of epithelial mitochondrial networks and loss of mitochondria-associated cytochrome-C in inflamed human and murine colon
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    sciencedirect.com/science/article/pii/S1567724922000885
  108. Aug 2022
  109. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Obesity and Fatty Acids Promote Mitochondrial Translocation of STAT3 Through ROS-Dependent Mechanisms
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    ncbi.nlm.nih.gov/pmc/articles/PMC9344057/
  110. May 2022
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    Integrative analysis of mitochondrial metabolic dynamics in reprogramming human fibroblast cells
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    Interactomic analysis reveals a homeostatic role for the HIV restriction factor TRIM5α in mitophagy
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    Mitochondrial LETM1 drives ionic and molecular clock rhythms in circadian pacemaker neurons
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  114. Apr 2022
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    Energetic metabolic reprogramming in Jurkat DFF40-deficient cancer cells
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    link.springer.com/article/10.1007/s11010-022-04433-0
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    Filamentous GLS1 promotes ROS-induced apoptosis upon glutamine deprivation via insufficient asparagine synthesis
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  117. Mar 2022
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    Age-associated decline of MondoA drives cellular senescence through impaired autophagy and mitochondrial homeostasis
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  119. Jan 2022
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    The long noncoding RNA glycoLINC assembles a lower glycolytic metabolon to promote glycolysis
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    Regulation of reverse electron transfer at mitochondrial complex I by unconventional Notch action in cancer stem cells
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