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    Pharmacological activation of sigma-1 receptor by clinically approved drugs enhances KV1.5 channel activity in the pulmonary circulation
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  3. Oct 2026
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    Enhanced liver regeneration via targeted mRNA delivery for partial in vivo reprogramming
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    Gut microbiota generate dinitrosyl iron complexes with cardiometabolic benefits
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    MRE11 proximal polyadenylation site-mediated looping impacts transcription and genomic stability
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    DUSP6 is upregulated in metastasis and influences migration and metabolism in pancreatic cancer cells
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  13. Sep 2025
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    ALKBH1 drives tumorigenesis and drug resistance via tRNA decoding reprogramming and codon-biased translation
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    Pharmacologic interrogation of USP28 cellular function in p53 signaling
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    Design of a selective peptide inhibitor targeting KDM5C demethylase activity
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    Adenylate cyclase 10 promotes brown adipose tissue thermogenesis
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    CAF-1 promotes efficient PrimPol recruitment to nascent DNA for single-stranded DNA gap formation
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    The splicing factor CCAR1 regulates the Fanconi anemia/BRCA pathway
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  27. Feb 2024
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    A Phase 1 Expansion Cohort Study Evaluating the Safety and Efficacy of the CHK1 Inhibitor LY2880070 with Low-Dose Gemcitabine in Metastatic Pancreatic Adenocarcinoma Patients
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    Sequencing-based functional assays for classification of BRCA2 variants in mouse ESCs
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    Gene Augmentation of CHM Using Non-Viral Episomal Vectors in Models of Choroideremia
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    TET2-mediated mRNA demethylation regulates leukemia stem cell homing and self-renewal
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    Vincristine Enhances the Efficacy of MEK Inhibitors in Preclinical Models of KRAS-mutant Colorectal Cancer
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  39. Jul 2023
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    Identification of an Imidazopyridine-based Compound as an Oral Selective Estrogen Receptor Degrader for Breast Cancer Therapy
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    Combining MEK and SRC inhibitors for treatment of colorectal cancer demonstrate increased efficacy in vitro but not in vivo
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  45. Jan 2023
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    Targeting KRAS-mutant stomach/colorectal tumors by disrupting the ERK2-p53 complex
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    METTL16 drives leukemogenesis and leukemia stem cell self-renewal by reprogramming BCAA metabolism
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    Integrated multi-omics analysis of adverse cardiac remodeling and metabolic inflexibility upon ErbB2 and ERRα deficiency
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  50. Jul 2022
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    ERα and ERβ Homodimers in the Same Cellular Context Regulate Distinct Transcriptomes and Functions
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  52. Jul 2021
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    SIRT4 is an early regulator of branched-chain amino acid catabolism that promotes adipogenesis
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  54. Apr 2021
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    Blocking Fra-1 sensitizes triple-negative breast cancer to PARP inhibitor
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  56. Mar 2021
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    The Oncogenic Helicase ALC1 Regulates PARP Inhibitor Potency by Trapping PARP2 at DNA Breaks
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  58. Oct 2020
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    MYC Promotes Bone Marrow Stem Cell Dysfunction in Fanconi Anemia
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  60. Sep 2020
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    RNA Demethylase ALKBH5 Selectively Promotes Tumorigenesis and Cancer Stem Cell Self-Renewal in Acute Myeloid Leukemia
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    WAPL-Dependent Repair of Damaged DNA Replication Forks Underlies Oncogene-Induced Loss of Sister Chromatid Cohesion
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    Myoferlin Is a Yet Unknown Interactor of the Mitochondrial Dynamics’ Machinery in Pancreas Cancer Cells
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  64. Jan 2020
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  66. Nov 2017
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    IFN‐gamma priming of adipose‐derived stromal cells at “physiological” hypoxia
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    BET Bromodomain Proteins Function as Master Transcription Elongation Factors Independent of CDK9 Recruitment
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