108 Matching Annotations
  1. Last 7 days
  2. www.science.org www.science.org
    ARL3 GTPases facilitate ODA16 unloading from IFT in motile cilia
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    1. scibot 20 Dec 2024
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      DOI: 10.1126/sciadv.adq2950

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    science.org/doi/10.1126/sciadv.adq2950
  3. Dec 2024
  4. www.sciencedirect.com www.sciencedirect.com
    m6A sites in the coding region trigger translation-dependent mRNA decay
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    1. scibot 02 Dec 2024
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    sciencedirect.com/science/article/pii/S1097276524008736
  5. Nov 2024
  6. www.sciencedirect.com www.sciencedirect.com
    Residue Y362 is crucial for FLIPL to impart catalytic activity to pro-caspase-8 to suppress necroptosis
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    1. scibot 11 Nov 2024
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    sciencedirect.com/science/article/pii/S2211124724013172
  7. Sep 2024
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ARL3 GTPases facilitate ODA16 unloading from IFT in motile cilia
    1
    1. scibot 12 Sep 2024
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      DOI: 10.1126/sciadv.adq2950

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    ncbi.nlm.nih.gov/pmc/articles/PMC11373600/
  9. www.cell.com www.cell.com
    TEX264 drives selective autophagy of DNA lesions to promote DNA repair and cell survival
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    1. scibot 12 Sep 2024
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    cell.com/cell/fulltext/S0092-8674(24)00911-5
  10. Aug 2024
  11. www.nature.com www.nature.com
    GSG1L suppresses AMPA receptor-mediated synaptic transmission and uniquely modulates AMPA receptor kinetics in hippocampal neurons
    1
    1. scibot 02 Aug 2024
      abbit anti-HA antibody

      DOI: 10.1038/ncomms10873

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    nature.com/ncomms/2016/160302/ncomms10873/full/ncomms10873.html
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    Molecular mechanism of distinct chemokine engagement and functional divergence of the human Duffy antigen receptor
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    1. scibot 01 Aug 2024
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    sciencedirect.com/science/article/pii/S0092867424007657
  13. Jul 2024
  14. www.sciencedirect.com www.sciencedirect.com
    Mast cell secretory granule fusion with amphisomes coordinates their homotypic fusion and release of exosomes
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    1. scibot 12 Jul 2024
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      DOI: 10.1016/j.celrep.2024.114482

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    sciencedirect.com/science/article/pii/S2211124724008118
  15. May 2024
  16. www.sciencedirect.com www.sciencedirect.com
    The Neurog2-Tbr2 axis forms a continuous transition to the neurogenic gene expression state in neural stem cells
    1
    1. scibot 24 May 2024
      RRID:AB_631618

      DOI: 10.1016/j.devcel.2024.04.019

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    sciencedirect.com/science/article/pii/S1534580724002946
  17. Apr 2024
  18. dx.doi.org dx.doi.org
    The role of microtubule-associated protein tau in netrin-1 attractive signaling
    1
    1. scibot 04 Apr 2024
      RRID:AB_631618

      DOI: 10.1242/jcs.261244

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    dx.doi.org/10.1242/jcs.261244
  19. Mar 2024
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    VCF1 is a p97/VCP cofactor promoting recognition of ubiquitylated p97-UFD1-NPL4 substrates
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    1. scibot 22 Mar 2024
      RRID:AB_631618

      DOI: 10.1038/s41467-024-46760-4

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    ncbi.nlm.nih.gov/pmc/articles/PMC10950897/
  21. www.sciencedirect.com www.sciencedirect.com
    MOF-mediated acetylation of UHRF1 enhances UHRF1 E3 ligase activity to facilitate DNA methylation maintenance
    1
    1. scibot 06 Mar 2024
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      DOI: 10.1016/j.celrep.2024.113908

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    sciencedirect.com/science/article/pii/S2211124724002365
  22. Feb 2024
  23. academic.oup.com academic.oup.com
    NGAL Mediates Anaplastic Thyroid Carcinoma Cells Survival Through FAS/CD95 Inhibition
    1
    1. scibot 27 Feb 2024
      RRID:AB_631618

      DOI: 10.1210/endocr/bqad190

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    academic.oup.com/endo/article-abstract/165/2/bqad190/7471656
  24. Nov 2023
  25. www.biorxiv.org www.biorxiv.org
    Collapse of late endosomal pH elicits a rapid Rab7 response via V-ATPase and RILP
    1
    1. scibot 03 Nov 2023
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      DOI: 10.1101/2023.10.24.563658

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    biorxiv.org/content/10.1101/2023.10.24.563658v1
  26. Oct 2023
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phosphorylated YBX2 is stabilized to promote glycolysis in brown adipocytes
    1
    1. scibot 20 Oct 2023
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      DOI: 10.1016/j.isci.2023.108091

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    ncbi.nlm.nih.gov/pmc/articles/PMC10583057/
  28. www.sciencedirect.com www.sciencedirect.com
    Gcn5- and Bre1-mediated Set2 degradation promotes chronological aging of Saccharomyces cerevisiae
    1
    1. scibot 13 Oct 2023
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      DOI: 10.1016/j.celrep.2023.113186

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    sciencedirect.com/science/article/pii/S2211124723011981
  29. Feb 2023
  30. www.sciencedirect.com www.sciencedirect.com
    Inducing primary brainstem gliomas in genetically engineered mice using RCAS/TVA retroviruses and Cre/loxP recombination
    1
    1. scibot 17 Feb 2023
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      DOI: 10.1016/j.xpro.2023.102094

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    sciencedirect.com/science/article/pii/S2666166723000527
  31. Jan 2023
  32. www.sciencedirect.com www.sciencedirect.com
    Cyclin E-induced replicative stress drives p53-dependent whole-genome duplication
    1
    1. scibot 21 Jan 2023
      RRID:AB_631618

      DOI: 10.1016/j.cell.2022.12.036

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    sciencedirect.com/science/article/pii/S0092867422015793
  33. Nov 2022
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Spatial Definition of the Human Progesterone Receptor-B Transcriptional Complex
    1
    1. scibot 04 Nov 2022
      AB_631618

      DOI: 10.1016/j.isci.2022.105321

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    ncbi.nlm.nih.gov/pmc/articles/PMC9618773/
  35. Oct 2022
  36. www.embopress.org www.embopress.org
    Chromatin remodeling is required for sRNA-guided DNA elimination in Paramecium
    1
    1. scibot 13 Oct 2022
      RRID:AB_631618

      DOI: 10.15252/embj.2022111839

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    embopress.org/doi/10.15252/embj.2022111839
  37. Aug 2022
  38. www.sciencedirect.com www.sciencedirect.com
    The AMPK-HOXB9-KRAS axis regulates lung adenocarcinoma growth in response to cellular energy alterations
    1
    1. scibot 26 Aug 2022
      RRID:AB_631618

      DOI: 10.1016/j.celrep.2022.111210

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    sciencedirect.com/science/article/pii/S2211124722010270
  39. May 2022
  40. www.sciencedirect.com www.sciencedirect.com
    The epilepsy-associated protein PCDH19 undergoes NMDA receptor-dependent proteolytic cleavage and regulates the expression of immediate-early genes
    1
    1. scibot 26 May 2022
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      DOI: 10.1016/j.celrep.2022.110857

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    sciencedirect.com/science/article/pii/S2211124722006301
  41. Apr 2022
  42. elifesciences.org elifesciences.org
    Evolutionary conservation of centriole rotational asymmetry in the human centrosome
    1
    1. scibot 07 Apr 2022
      RRID:AB_631618

      DOI: 10.7554/eLife.72382

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    elifesciences.org/articles/72382
  43. Mar 2022
  44. www.sciencedirect.com www.sciencedirect.com
    The XRN1-regulated RNA helicase activity of YTHDC2 ensures mouse fertility independently of m6A recognition
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    1. scibot 20 Mar 2022
      RRID:AB_631618

      DOI: 10.1016/j.molcel.2022.02.034

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    sciencedirect.com/science/article/pii/S1097276522002088
  45. Jan 2022
  46. www.sciencedirect.com www.sciencedirect.com
    Acetylation-dependent regulation of BRAF oncogenic function
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    1. scibot 19 Jan 2022
      RRID:AB_631618

      DOI: 10.1016/j.celrep.2021.110250

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    sciencedirect.com/science/article/pii/S2211124721017629
  47. Dec 2021
  48. www.sciencedirect.com www.sciencedirect.com
    Suppression of MYC transcription activators by the immune cofactor NPR1 fine-tunes plant immune responses
    1
    1. scibot 15 Dec 2021
      RRID:AB_631618

      DOI: 10.1016/j.celrep.2021.110125

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    sciencedirect.com/science/article/pii/S2211124721016211
  49. Nov 2021
  50. www.sciencedirect.com www.sciencedirect.com
    Interplay between protein acetylation and ubiquitination controls MCL1 protein stability
    1
    1. scibot 10 Nov 2021
      sc-805

      DOI: 10.1016/j.celrep.2021.109988

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    sciencedirect.com/science/article/pii/S2211124721014674
  51. Sep 2021
  52. www.sciencedirect.com www.sciencedirect.com
    Lrp1 is a host entry factor for Rift Valley fever virus
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    1. scibot 24 Sep 2021
      RRID:AB_631618

      DOI: 10.1016/j.cell.2021.09.001

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    sciencedirect.com/science/article/pii/S0092867421010485
  53. Aug 2021
  54. www.sciencedirect.com www.sciencedirect.com
    FAF1 Regulates Antiviral Immunity by Inhibiting MAVS but Is Antagonized by Phosphorylation upon Viral Infection
    1
    1. scibot 09 Aug 2021
      RRID:AB_631618

      DOI: 10.1016/j.chom.2018.10.006

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    sciencedirect.com/science/article/pii/S1931312818305444
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulation of platelet-activating factor-mediated interleukin-6 promoter activation by the 48 kDa but not the 45 kDa isoform of protein tyrosine phosphatase non-receptor type 2
    1
    1. scibot 06 Aug 2021
      RRID:AB_631618

      DOI: 10.1186/s13578-019-0316-9

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    ncbi.nlm.nih.gov/pmc/articles/PMC6593612/
  56. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 05 Aug 2021
      RRID:AB_631618

      DOI: 10.1016/j.devcel.2018.11.035

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    sciencedirect.com/science/article/pii/S1534580718310189
  57. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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      RRID:AB_631618

      DOI: 10.1016/j.celrep.2018.11.025

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    sciencedirect.com/science/article/pii/S2211124718317716
  58. www.sciencedirect.com www.sciencedirect.com
    Exocyst protein subnetworks integrate Hippo and mTOR signaling to promote virus detection and cancer
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      DOI: 10.1016/j.celrep.2021.109491

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    sciencedirect.com/science/article/pii/S2211124721009189
  59. Jul 2021
  60. mcr.aacrjournals.org mcr.aacrjournals.org
    Intron 1-Mediated Regulation of EGFR Expression In EGFR-Dependent Malignancies is Mediated by AP-1 and BET Proteins
    1
    1. scibot 31 Jul 2021
      anti-HA-HRP

      DOI: 10.1158/1541-7786.MCR-19-0747

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    mcr.aacrjournals.org/content/17/11/2208
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      RRID:AB_631618

      DOI: 10.1016/j.celrep.2018.11.035

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    ncbi.nlm.nih.gov/pmc/articles/PMC6342284/
  62. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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      RRID:AB_631618

      DOI: 10.1016/j.celrep.2018.11.035

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    sciencedirect.com/science/article/pii/S2211124718317984
  63. www.sciencedirect.com www.sciencedirect.com
    ASF1a Promotes Non-homologous End Joining Repair by Facilitating Phosphorylation of MDC1 by ATM at Double-Strand Breaks
    2
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      AB_631618

      DOI: 10.1016/j.molcel.2017.08.021

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      RRID:AB_631618

      DOI: 10.1016/j.molcel.2017.08.021

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    sciencedirect.com/science/article/pii/S1097276517306184
  64. www.sciencedirect.com www.sciencedirect.com
    Foxp1 Is Indispensable for Ductal Morphogenesis and Controls the Exit of Mammary Stem Cells from Quiescence
    1
    1. scibot 27 Jul 2021
      SC-805

      DOI: 10.1016/j.devcel.2018.10.001

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    sciencedirect.com/science/article/pii/S1534580718308220
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Acetylation Blocks cGAS Activity and Inhibits Self-DNA-Induced Autoimmunity
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    1. scibot 14 Jul 2021
      RRID:AB_631618

      DOI: 10.1016/j.cell.2019.01.016

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    Targeted protein degradation reveals a direct role of SPT6 in RNAPII elongation and termination
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  67. May 2021
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    A Non-canonical PDK1-RSK Signal Diminishes Pro-caspase-8-Mediated Necroptosis Blockade
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    Centrosomal Localization of RXRα Promotes PLK1 Activation and Mitotic Progression and Constitutes a Tumor Vulnerability
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  70. Mar 2021
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    Negative feedback couples Hippo pathway activation with Kibra degradation independent of Yorkie-mediated transcription
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  72. Feb 2021
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    The IMiD target CRBN determines HSP90 activity toward transmembrane proteins essential in multiple myeloma
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  74. Jan 2021
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    Chk1 promotes non-homologous end joining in G1 through direct phosphorylation of ASF1A
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    The ubiquitin ligase RFWD3 is required for translesion DNA synthesis
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    TRIM11 Prevents and Reverses Protein Aggregation and Rescues a Mouse Model of Parkinson’s Disease
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    Dynamin-2 Regulates Postsynaptic Cytoskeleton Organization and Neuromuscular Junction Development
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    MED19 Regulates Adipogenesis and Maintenance of White Adipose Tissue Mass by Mediating PPARγ-Dependent Gene Expression
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  82. Sep 2020
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    Regulation of S100A8 Stability by RNF5 in Intestinal Epithelial Cells Determines Intestinal Inflammation and Severity of Colitis
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    Acetylation-Dependent Deubiquitinase OTUD3 Controls MAVS Activation in Innate Antiviral Immunity
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    Phosphorylation‐dependent osterix degradation negatively regulates osteoblast differentiation
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    Intramembrane proteolysis of an extracellular serine protease, epithin/PRSS14, enables its intracellular nuclear function
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    Endogenous Cyclin D1 Promotes the Rate of Onset and Magnitude of Mitogenic Signaling via Akt1 Ser473 Phosphorylation
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    Extensive SUMO Modification of Repressive Chromatin Factors Distinguishes Pluripotent from Somatic Cells
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    FRMD8 promotes inflammatory and growth factor signalling by stabilising the iRhom/ADAM17 sheddase complex
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    Phosphorylation of iRhom2 at the plasma membrane controls mammalian TACE-dependent inflammatory and growth factor signalling
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      rabbit anti-HA

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    Diabetes enhances translation of Cd40 mRNA in murine retinal Müller glia via a 4E-BP1/2-dependent mechanism
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  92. Jan 2020
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    A Comprehensive Structure-Function Study of Neurogenin3 Disease-Causing Alleles during Human Pancreas and Intestinal Organoid Development
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    Conformational Sensors and Domain Swapping Reveal Structural and Functional Differences between β-Arrestin Isoforms
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    Histone Deacetylase SIRT1 Targets Plk2 to Regulate Centriole Duplication
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    Phosphorylation-mediated interactions with TOPBP1 couple 53BP1 and 9-1-1 to control the G1 DNA damage checkpoint
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    Proteomics Links Ubiquitin Chain Topology Change to Transcription Factor Activation
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    An mTORC1-to-CDK1 Switch Maintains Autophagy Suppression during Mitosis
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    Lactate Is a Natural Suppressor of RLR Signaling by Targeting MAVS
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    PDGFR-β Signaling Regulates Cardiomyocyte Proliferation and Myocardial Regeneration
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    The p97–Ataxin 3 complex regulates homeostasis of the DNA damage response E3 ubiquitin ligase RNF8
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      DOI: 10.15252/embj.2019102361

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    Disease-associated mutations in human TUBB3 disturb netrin repulsive signaling
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    Adhesive L1CAM-Robo Signaling Aligns Growth Cone F-Actin Dynamics to Promote Axon-Dendrite Fasciculation in C. elegans
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    MST1 Negatively Regulates TNFα-Induced NF-κB Signaling through Modulating LUBAC Activity
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    Structural and Functional Insights into Host Death Domains Inactivation by the Bacterial Arginine GlcNAcyltransferase Effector
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    OTUB2 Promotes Cancer Metastasis via Hippo-Independent Activation of YAP and TAZ
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    Phosphorylation of the Ribosomal Protein RPL12/uL11 Affects Translation during Mitosis
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    Therapeutic Ablation of Gain-of-Function Mutant p53 in Colorectal Cancer Inhibits Stat3-Mediated Tumor Growth and Invasion
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    Yorkie Functions at the Cell Cortex to Promote Myosin Activation in a Non-transcriptional Manner
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    BAI1 Suppresses Medulloblastoma Formation by Protecting p53 from Mdm2-Mediated Degradation
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    The Dietary Supplement Chondroitin-4-Sulfate Exhibits Oncogene-Specific Pro-tumor Effects on BRAF V600E Melanoma Cells
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    EP300-Mediated Lysine 2-Hydroxyisobutyrylation Regulates Glycolysis
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    The SS18-SSX Oncoprotein Hijacks KDM2B-PRC1.1 to Drive Synovial Sarcoma
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    Dicer-like Enzymes with Sequence Cleavage Preferences
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    Remote Coupled Drastic β-Barrel to β-Sheet Transition of the Protein Translocation Motor
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    Molecular Dissection of Neuroligin 2 and Slitrk3 Reveals an Essential Framework for GABAergic Synapse Development
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    Tension-Dependent Stretching Activates ZO-1 to Control the Junctional Localization of Its Interactors
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    Astroglial major histocompatibility complex class I following immune activation leads to behavioral and neuropathological changes
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    An Eya1-Notch axis specifies bipotential epibranchial differentiation in mammalian craniofacial morphogenesis.
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    NOTCH2 Hajdu-Cheney Mutations Escape SCFFBW7-Dependent Proteolysis to Promote Osteoporosis
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    Increased GSNOR Expression during Aging Impairs Cognitive Function and Decreases S-Nitrosation of CaMKIIα
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    H3.3K27M Cooperates with Trp53 Loss and PDGFRA Gain in Mouse Embryonic Neural Progenitor Cells to Induce Invasive High-Grade Gliomas
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    Prohibitin 2 Is an Inner Mitochondrial Membrane Mitophagy Receptor
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    Uncoupling of UNC5C with Polymerized TUBB3 in Microtubules Mediates Netrin-1 Repulsion
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    Cdc25A Is a Critical Mediator of Ischemic Neuronal Death In Vitro and In Vivo
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    EDEM Function in ERAD Protects against Chronic ER Proteinopathy and Age-Related Physiological Decline in Drosophila
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    An Interaction Landscape of Ubiquitin Signaling
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    Toxic PR Poly-Dipeptides Encoded by the C9orf72 Repeat Expansion Target LC Domain Polymers
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    The novel SH3 domain protein Dlish/CG10933 mediates fat signaling in Drosophila by binding and regulating Dachs
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    Germline NLRP1 Mutations Cause Skin Inflammatory and Cancer Susceptibility Syndromes via Inflammasome Activation
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  142. www.nature.com www.nature.com
    GSG1L suppresses AMPA receptor-mediated synaptic transmission and uniquely modulates AMPA receptor kinetics in hippocampal neurons
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