115 Matching Annotations
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    Proximity interactome mapping furthers a role for spinophilin in protein homeostasis
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  3. Aug 2025
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    MAVS phosphorylation acts as a cellular stress sensor that modulates antiviral immunity
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    Using CCDC6 immunostaining in conjunction with the RAD51 HRD assay as a novel approach to expand PARPi treatment eligibility in HGSOC patients
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    biorxiv.org/content/10.1101/2025.07.29.667411v1
  6. May 2025
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    A critical role of Neuroligin 2 C-terminus in OCD and social behavior
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    Collapse of late endosomal pH elicits a rapid Rab7 response via the V-ATPase and RILP
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    Activity-dependent degradation of Kv4.2 contributes to synaptic plasticity and behavior in Angelman syndrome model mice
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  10. Jan 2025
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    Revisiting phosphoregulation of Cdc25C during M-phase induction
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  12. Dec 2024
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    ARL3 GTPases facilitate ODA16 unloading from IFT in motile cilia
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    m6A sites in the coding region trigger translation-dependent mRNA decay
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    Residue Y362 is crucial for FLIPL to impart catalytic activity to pro-caspase-8 to suppress necroptosis
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    ARL3 GTPases facilitate ODA16 unloading from IFT in motile cilia
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    TEX264 drives selective autophagy of DNA lesions to promote DNA repair and cell survival
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    GSG1L suppresses AMPA receptor-mediated synaptic transmission and uniquely modulates AMPA receptor kinetics in hippocampal neurons
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    Molecular mechanism of distinct chemokine engagement and functional divergence of the human Duffy antigen receptor
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    Mast cell secretory granule fusion with amphisomes coordinates their homotypic fusion and release of exosomes
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    The Neurog2-Tbr2 axis forms a continuous transition to the neurogenic gene expression state in neural stem cells
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    The role of microtubule-associated protein tau in netrin-1 attractive signaling
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  29. Mar 2024
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    VCF1 is a p97/VCP cofactor promoting recognition of ubiquitylated p97-UFD1-NPL4 substrates
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    MOF-mediated acetylation of UHRF1 enhances UHRF1 E3 ligase activity to facilitate DNA methylation maintenance
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    NGAL Mediates Anaplastic Thyroid Carcinoma Cells Survival Through FAS/CD95 Inhibition
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  34. Nov 2023
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    Collapse of late endosomal pH elicits a rapid Rab7 response via V-ATPase and RILP
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  36. Oct 2023
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    Phosphorylated YBX2 is stabilized to promote glycolysis in brown adipocytes
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    Gcn5- and Bre1-mediated Set2 degradation promotes chronological aging of Saccharomyces cerevisiae
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    Inducing primary brainstem gliomas in genetically engineered mice using RCAS/TVA retroviruses and Cre/loxP recombination
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    Cyclin E-induced replicative stress drives p53-dependent whole-genome duplication
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    Spatial Definition of the Human Progesterone Receptor-B Transcriptional Complex
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    Chromatin remodeling is required for sRNA-guided DNA elimination in Paramecium
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  47. Aug 2022
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    The AMPK-HOXB9-KRAS axis regulates lung adenocarcinoma growth in response to cellular energy alterations
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    The epilepsy-associated protein PCDH19 undergoes NMDA receptor-dependent proteolytic cleavage and regulates the expression of immediate-early genes
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    Evolutionary conservation of centriole rotational asymmetry in the human centrosome
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  53. Mar 2022
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    The XRN1-regulated RNA helicase activity of YTHDC2 ensures mouse fertility independently of m6A recognition
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    Acetylation-dependent regulation of BRAF oncogenic function
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    Suppression of MYC transcription activators by the immune cofactor NPR1 fine-tunes plant immune responses
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    Interplay between protein acetylation and ubiquitination controls MCL1 protein stability
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    Lrp1 is a host entry factor for Rift Valley fever virus
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  63. Aug 2021
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    FAF1 Regulates Antiviral Immunity by Inhibiting MAVS but Is Antagonized by Phosphorylation upon Viral Infection
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    Regulation of platelet-activating factor-mediated interleukin-6 promoter activation by the 48 kDa but not the 45 kDa isoform of protein tyrosine phosphatase non-receptor type 2
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    Exocyst protein subnetworks integrate Hippo and mTOR signaling to promote virus detection and cancer
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  69. Jul 2021
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    Intron 1-Mediated Regulation of EGFR Expression In EGFR-Dependent Malignancies is Mediated by AP-1 and BET Proteins
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    ASF1a Promotes Non-homologous End Joining Repair by Facilitating Phosphorylation of MDC1 by ATM at Double-Strand Breaks
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    Foxp1 Is Indispensable for Ductal Morphogenesis and Controls the Exit of Mammary Stem Cells from Quiescence
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    Acetylation Blocks cGAS Activity and Inhibits Self-DNA-Induced Autoimmunity
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    Targeted protein degradation reveals a direct role of SPT6 in RNAPII elongation and termination
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  77. May 2021
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    A Non-canonical PDK1-RSK Signal Diminishes Pro-caspase-8-Mediated Necroptosis Blockade
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    Centrosomal Localization of RXRα Promotes PLK1 Activation and Mitotic Progression and Constitutes a Tumor Vulnerability
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  80. Mar 2021
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    Negative feedback couples Hippo pathway activation with Kibra degradation independent of Yorkie-mediated transcription
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  82. Feb 2021
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    The IMiD target CRBN determines HSP90 activity toward transmembrane proteins essential in multiple myeloma
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    Chk1 promotes non-homologous end joining in G1 through direct phosphorylation of ASF1A
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    The ubiquitin ligase RFWD3 is required for translesion DNA synthesis
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    TRIM11 Prevents and Reverses Protein Aggregation and Rescues a Mouse Model of Parkinson’s Disease
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  89. Oct 2020
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    Dynamin-2 Regulates Postsynaptic Cytoskeleton Organization and Neuromuscular Junction Development
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    MED19 Regulates Adipogenesis and Maintenance of White Adipose Tissue Mass by Mediating PPARγ-Dependent Gene Expression
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  92. Sep 2020
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    Regulation of S100A8 Stability by RNF5 in Intestinal Epithelial Cells Determines Intestinal Inflammation and Severity of Colitis
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    Acetylation-Dependent Deubiquitinase OTUD3 Controls MAVS Activation in Innate Antiviral Immunity
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    Intramembrane proteolysis of an extracellular serine protease, epithin/PRSS14, enables its intracellular nuclear function
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    Endogenous Cyclin D1 Promotes the Rate of Onset and Magnitude of Mitogenic Signaling via Akt1 Ser473 Phosphorylation
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    Extensive SUMO Modification of Repressive Chromatin Factors Distinguishes Pluripotent from Somatic Cells
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    FRMD8 promotes inflammatory and growth factor signalling by stabilising the iRhom/ADAM17 sheddase complex
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    Phosphorylation of iRhom2 at the plasma membrane controls mammalian TACE-dependent inflammatory and growth factor signalling
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    Diabetes enhances translation of Cd40 mRNA in murine retinal Müller glia via a 4E-BP1/2-dependent mechanism
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  102. Jan 2020
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    A Comprehensive Structure-Function Study of Neurogenin3 Disease-Causing Alleles during Human Pancreas and Intestinal Organoid Development
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    Conformational Sensors and Domain Swapping Reveal Structural and Functional Differences between β-Arrestin Isoforms
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    Histone Deacetylase SIRT1 Targets Plk2 to Regulate Centriole Duplication
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    Proteomics Links Ubiquitin Chain Topology Change to Transcription Factor Activation
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    An mTORC1-to-CDK1 Switch Maintains Autophagy Suppression during Mitosis
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    Lactate Is a Natural Suppressor of RLR Signaling by Targeting MAVS
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    PDGFR-β Signaling Regulates Cardiomyocyte Proliferation and Myocardial Regeneration
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    The p97–Ataxin 3 complex regulates homeostasis of the DNA damage response E3 ubiquitin ligase RNF8
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    Disease-associated mutations in human TUBB3 disturb netrin repulsive signaling
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    Adhesive L1CAM-Robo Signaling Aligns Growth Cone F-Actin Dynamics to Promote Axon-Dendrite Fasciculation in C. elegans
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    MST1 Negatively Regulates TNFα-Induced NF-κB Signaling through Modulating LUBAC Activity
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    Structural and Functional Insights into Host Death Domains Inactivation by the Bacterial Arginine GlcNAcyltransferase Effector
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    OTUB2 Promotes Cancer Metastasis via Hippo-Independent Activation of YAP and TAZ
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    Phosphorylation of the Ribosomal Protein RPL12/uL11 Affects Translation during Mitosis
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    Therapeutic Ablation of Gain-of-Function Mutant p53 in Colorectal Cancer Inhibits Stat3-Mediated Tumor Growth and Invasion
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