112 Matching Annotations
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    An NAD+-responsive adipose signal coordinates inter-organ defense against muscle atrophy
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  3. Oct 2026
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    Vpu protects HIV-infected cells from antibody-dependent cellular phagocytosis by counteracting tetherin
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    sciencedirect.com/science/article/pii/S2211124726011599
  5. Sep 2026
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    Cancers modulate processing and presentation of p53 neoantigens to evade T cell detection
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    Targeting PRMT5 inhibitor-induced adaptation in pancreatic cancer with the RBM39 degrader indisulam
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    pmc.ncbi.nlm.nih.gov/articles/PMC13530115/
  8. Jul 2026
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    Enteropathogenic Escherichia coli-mediated fast and coordinated Ca²+ responses regulate NF-κB activation
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    Distinct metabolic dependency on BCAA defines cancer stemness and malignancy in human triple-negative breast cancer
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    Systematic discovery of pathogen effector functions across human pathogens and pathways
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  12. May 2026
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    Andrographolide attenuates microglial senescence in Alzheimer’s disease mice by suppressing the STAT3 signaling
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  14. Apr 2026
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    RNA dicing promotes the expression of an oncogenic JAK1 isoform
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  16. Feb 2026
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    Triglycerides induce endoplasmic reticulum lipid bilayer stress to activate PERK and enhance antifungal immunity
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  18. Jan 2026
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    NCOA1 is a gatekeeper of the sexually dimorphic thermogenic activity of white adipose tissue
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  20. Dec 2025
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    CDK2 inhibition enhances CDK4/6 inhibitor antitumor activity in comprehensive breast cancer PDX model screen
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  22. Oct 2025
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    Metabolic Alterations driven by PFKFB3 upregulation confer Resistance to Trastuzumab in HER2-Positive Breast Cancer
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    USP9X is a mechanosensitive deubiquitinase that controls tumor cell invasiveness and drug response through YAP stabilization
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  25. Sep 2025
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    RBM39 degrader invigorates innate immunity to eradicate neuroblastoma despite cancer cell plasticity
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    ADSL deficiency is a secondary mitochondrial disease affecting organelle homeostasis and ERK2/AKT signaling in a linear genotype-phenotype relation
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  28. Aug 2025
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    PKD and scaffold NHERF1 mediate hypoxia-induced gene expression in 3T3-L1 adipocytes
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    Aberrantly Expressed Mitochondrial Lipid Kinase, AGK Activates JAK2-Histone H3 Axis and BCR Signal: A Mechanistic Study with Implication in CLL Therapy
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  32. Jul 2025
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    Epigenetic profiling identifies markers of endocrine resistance and therapeutic options for metastatic castration-resistant prostate cancer
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    Helicobacter Pylori Infection Triggers PERK-Associated Survivin Loss in Gastric Tissue Samples and Cell Lines
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    Regulation of epigenetics and chromosome structure by human ORC2
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  37. May 2025
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    The context-dependent epigenetic and organogenesis programs determine 3D vs. 2D cellular fitness of MYC-driven murine liver cancer cells
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    Lipid droplet efferocytosis attenuates proinflammatory signaling in macrophages via TREM2- and MS4A7-dependent mechanisms
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    Inositol polyphosphate multikinase regulates Th1 and Th17 cell differentiation by controlling Akt-mTOR signaling
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  44. Nov 2024
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    GM1 Oligosaccharide Ameliorates Rett Syndrome Phenotypes In Vitro and In Vivo via Trk Receptor Activation
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    SUMOylation of protein phosphatase 5 regulates phosphatase activity and substrate release
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  47. Sep 2024
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    The ULK1 effector BAG2 regulates autophagy initiation by modulating AMBRA1 localization
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  50. Aug 2024
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  52. Jul 2024
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    Multivalent GU-rich oligonucleotides sequester TDP-43 in the nucleus by inducing high molecular weight RNP complexes
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  54. Jun 2024
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    Tumour microenvironment programming by an RNA–RNA-binding protein complex creates a druggable vulnerability in IDH-wild-type glioblastoma
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  56. Apr 2024
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    RAD52-dependent mitotic DNA synthesis is required for genome stability in Cyclin E1-overexpressing cells
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  58. Mar 2024
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    Histone lysine demethylase 4 family proteins maintain the transcriptional program and adrenergic cellular state of MYCN-amplified neuroblastoma
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    Coordinated ARP2/3 and glycolytic activities regulate the morphological and functional fitness of human CD8+ T cells
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  61. Feb 2024
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    Protein-folding chaperones predict structure-function relationships and cancer risk in BRCA1 mutation carriers
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    An alternative splicing signature defines the basal-like phenotype and predicts worse clinical outcome in pancreatic cancer
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  64. Jan 2024
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    Type 2 cytokine signaling in macrophages protects from cellular senescence and organismal aging
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  66. Oct 2023
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    Loss of function of the ALS-associated NEK1 kinase disrupts microtubule homeostasis and nuclear import
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    ASCL1-ERK1/2 Axis: ASCL1 restrains ERK1/2 via the dual specificity phosphatase DUSP6 to promote survival of a subset of neuroendocrine lung cancers
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    Stress response mechanisms in protein misfolding diseases: Profiling a cellular model of Huntington's disease
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    Loss of function of the ALS-associated NEK1 kinase disrupts microtubule homeostasis and nuclear import
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  73. Jul 2023
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    HIGD1A links SIRT1 activity to adipose browning by inhibiting the ROS/DNA damage pathway
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    FIRRM/C1orf112 is synthetic lethal with PICH and mediates RAD51 dynamics
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    Aquaporin-8 ameliorates hepatic steatosis through farnesoid X receptor in obese mice
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  80. Mar 2023
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    A central chaperone-like role for 14-3-3 proteins in human cells
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    COUP-TFII plays a role in cAMP-induced Schwann cell differentiation and in vitro myelination by upregulating Krox20
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    GPR143 controls ESCRT-dependent exosome biogenesis and promotes cancer metastasis
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  85. Jan 2023
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    SAYSD1 senses UFMylated ribosome to safeguard co-translational protein translocation at the endoplasmic reticulum
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    Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis
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    NF-κB/RelA controlled A20 limits TRAIL-induced apoptosis in pancreatic cancer
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  90. Dec 2022
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    AP1/Fra1 confers resistance to MAPK cascade inhibition in pancreatic cancer
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  92. Sep 2022
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    Cancer cell autophagy, reprogrammed macrophages, and remodeled vasculature in glioblastoma triggers tumor immunity
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  95. Aug 2022
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    Multi-facet roles of RNA editing in promoting loss-of-function of PODXL in cancer
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  97. Jun 2022
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    Genetic screens identify a context-specific PI3K/p27Kip1 node driving extrahepatic biliary cancer
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  99. Apr 2022
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  101. Mar 2022
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    A survey of optimal strategy for signature-based drug repositioning and an application to liver cancer
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  103. Feb 2022
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    Distinct MUNC lncRNA structural domains regulate transcription of different promyogenic factors
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  105. Jan 2022
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    Identification and functional characterization of transcriptional activators in human cells
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  107. Dec 2021
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    Lunapark-dependent formation of a virus-induced ER exit site contains multi-tubular ER junctions that promote viral ER-to-cytosol escape
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  109. Nov 2021
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    The ESCRT machinery counteracts Nesprin-2G-mediated mechanical forces during nuclear envelope repair
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  112. Sep 2021
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    Pericyte Insulin Receptors Modulate Retinal Vascular Remodeling and Endothelial Angiopoietin Signaling
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    SPT5 stabilization of promoter-proximal RNA polymerase II
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  115. Aug 2021
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    Excess dietary carbohydrate affects mitochondrial integrity as observed in brown adipose tissue
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  120. Jul 2021
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    ZMYND10 functions in a chaperone relay during axonemal dynein assembly
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    Morphological profiling of human T and NK lymphocytes by high-content cell imaging
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  123. May 2021
  124. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    UBTD1 regulates ceramide balance and endolysosomal positioning to coordinate EGFR signaling
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    Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains
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  126. Apr 2021
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    Cancer cells escape autophagy inhibition via NRF2-induced macropinocytosis
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    MAX Functions as a Tumor Suppressor and Rewires Metabolism in Small Cell Lung Cancer
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    GREB1: An evolutionarily conserved protein with a glycosyltransferase domain links ERα glycosylation and stability to cancer
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  130. Feb 2021
  131. www.nature.com www.nature.com
    Proteomic Profiling of Small Extracellular Vesicles Secreted by Human Pancreatic Cancer Cells Implicated in Cellular Transformation
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  132. Jan 2021
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    TGF-β1 increases permeability of ciliated airway epithelia via redistribution of claudin 3 from tight junction into cell nuclei
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  134. Nov 2020
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    A Novel Fibroblast Reporter Cell Line for in vitro Studies of Pulmonary Fibrosis
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    A Broad Response to Intracellular Long-Chain Polyphosphate in Human Cells
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  137. Oct 2020
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  149. Jan 2020
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