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Neurons sequester the cholesterol-inhibiting TFEB in oligodendrocyte cytoplasm to safeguard myelination and neural function

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1. scibot 09 Sep 2025
  
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  DOI: 10.1016/j.celrep.2025.116252
  
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sciencedirect.com/science/article/pii/S221112472501023X
Sep 2025
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Polyserine-mediated targeting of FAF2/UBXD8 ameliorates tau aggregation

1
1. scibot 03 Sep 2025
  
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  DOI: 10.1016/j.neuron.2025.08.002
  
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sciencedirect.com/science/article/pii/S0896627325005872
Apr 2025
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Pooled tagging and hydrophobic targeting of endogenous proteins for unbiased mapping of unfolded protein responses

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1. scibot 24 Apr 2025
  
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  DOI: 10.1016/j.molcel.2025.04.002
  
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sciencedirect.com/science/article/pii/S1097276525003053
Dec 2024
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Unveiling the physiological impact of ESCRT-dependent autophagosome closure by targeting the VPS37A ubiquitin E2 variant-like domain

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1. scibot 02 Dec 2024
  
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  DOI: 10.1016/j.celrep.2024.115016
  
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sciencedirect.com/science/article/pii/S2211124724013676
Sep 2024
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PUFFFIN: an ultra-bright, customisable, single-plasmid system for labelling cell neighbourhoods

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1. scibot 25 Sep 2024
  
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  DOI: 10.1038/s44318-024-00154-w
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11405414/
Sep 2023
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Principles of assembly and regulation of condensates of Polycomb repressive complex 1 through phase separation

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1. scibot 30 Sep 2023
  
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  DOI: 10.1016/j.celrep.2023.113136
  
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Microtubule detyrosination by VASH1/SVBP is regulated by the conformational state of tubulin in the lattice

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1. scibot 19 Sep 2023
  
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  DOI: 10.1016/j.cub.2023.07.062
  
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sciencedirect.com/science/article/abs/pii/S0960982223010011
Jul 2023
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Different chromatin-scanning modes lead to targeting of compacted chromatin by pioneer factors FOXA1 and SOX2

2
1. scibot 08 Jul 2023
  
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  DOI: 10.1016/j.celrep.2023.112748
  
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2. scibot 08 Jul 2023
  
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  DOI: 10.1016/j.celrep.2023.112748
  
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sciencedirect.com/science/article/pii/S2211124723007593
Jun 2023
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Transcription factor HNF4α2 promotes osteogenesis and prevents bone abnormalities in mice with renal osteodystrophy

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1. scibot 03 Jun 2023
  
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  DOI: 10.1172/JCI159928
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10231994/
May 2023
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RRID4-html.html

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1. scibot 19 May 2023
  
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  DOI: 10.1172/jci159928
  
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52.53.155.43/f9fd2f1eaca8dfb8d5f96f6dd0870052839ec9f6/RRID4-html.html
Apr 2023
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GAGA-associated factor fosters loop formation in the Drosophila genome

1
1. scibot 27 Apr 2023
  
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  DOI: 10.1016/j.molcel.2023.03.011
  
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Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair

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1. scibot 14 Apr 2023
  
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  DOI: 10.1016/j.molcel.2023.03.021
  
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sciencedirect.com/science/article/pii/S1097276523002113
Jan 2023
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The selective autophagy adaptor p62/SQSTM1 forms phase condensates regulated by HSP27 that facilitate the clearance of damaged lysosomes via lysophagy

2
1. scibot 27 Jan 2023
  
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  DOI: 10.1016/j.celrep.2023.112037
  
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2. scibot 27 Jan 2023
  
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  DOI: 10.1016/j.celrep.2023.112037
  
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Protocol to study presynaptic protein synthesis in ex vivo mouse hippocampal slices using HaloTag technology

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1. scibot 21 Jan 2023
  
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  DOI: 10.1016/j.xpro.2022.101986
  
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sciencedirect.com/science/article/pii/S2666166722008668
Dec 2022
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Z-REX uncovers a bifurcation in function of Keap1 paralogs

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1. scibot 17 Dec 2022
  
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  DOI: 10.7554/eLife.83373
  
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elifesciences.org/articles/83373
Sep 2022
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CTCF DNA-binding domain undergoes dynamic and selective protein–protein interactions

1
1. scibot 22 Sep 2022
  
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  DOI: 10.1016/j.isci.2022.105011
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9474293/
Aug 2022
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Duplex Labeling and Manipulation of Neuronal Proteins Using Sequential CRISPR/Cas9 Gene Editing

1
1. scibot 02 Aug 2022
  
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  DOI: 10.1523/ENEURO.0056-22.2022
  
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eneuro.org/content/9/4/ENEURO.0056-22.2022
Jun 2022
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Presynaptic FMRP and local protein synthesis support structural and functional plasticity of glutamatergic axon terminals

1
1. scibot 22 Jun 2022
  
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  DOI: 10.1016/j.neuron.2022.05.024
  
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sciencedirect.com/science/article/pii/S0896627322005013
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Granger-causal inference of the lamellipodial actin regulator hierarchy by live cell imaging without perturbation

1
1. scibot 09 Jun 2022
  
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  DOI: 10.1016/j.cels.2022.05.003
  
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sciencedirect.com/science/article/pii/S2405471222002241
Apr 2022
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A particle size threshold governs diffusion and segregation of PAR-3 during cell polarization

1
1. scibot 14 Apr 2022
  
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  DOI: 10.1016/j.celrep.2022.110652
  
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sciencedirect.com/science/article/pii/S2211124722004041
Sep 2021
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Synaptotagmin 7 is targeted to the axonal plasma membrane through γ-secretase processing to promote synaptic vesicle docking in mouse hippocampal neurons

1
1. scibot 25 Sep 2021
  
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  DOI: 10.7554/eLife.67261
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8452306/
Jul 2021
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Glycoprotein nonmetastatic melanoma protein B ameliorates skeletal muscle lesions in a SOD1G93A mouse model of amyotrophic lateral sclerosis

2
1. scibot 27 Jul 2021
  
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  DOI: 10.1002/jnr.23619
  
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2. scibot 27 Jul 2021
  
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  DOI: 10.1002/jnr.23619
  
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onlinelibrary.wiley.com/doi/10.1002/jnr.23619/full
Feb 2021
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Mesoscale Modeling and Single-Nucleosome Tracking Reveal Remodeling of Clutch Folding and Dynamics in Stem Cell Differentiation

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1. scibot 28 Feb 2021
  
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  DOI: 10.1016/j.celrep.2020.108614
  
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sciencedirect.com/science/article/pii/S221112472031603X
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Graded titin cleavage progressively reduces tension and uncovers the source of A-band stability in contracting muscle

1
1. scibot 27 Feb 2021
  
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  DOI: 10.7554/eLife.64107
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7781594/
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NIX initiates mitochondrial fragmentation via DRP1 to drive epidermal differentiation

1
1. scibot 04 Feb 2021
  
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  DOI: 10.1016/j.celrep.2021.108689
  
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sciencedirect.com/science/article/pii/S2211124721000024
Sep 2020
elifesciences.org elifesciences.org

The novel ciliogenesis regulator DYRK2 governs Hedgehog signaling during mouse embryogenesis

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1. scibot 23 Sep 2020
  
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  DOI: 10.7554/eLife.57381
  
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elifesciences.org/articles/57381
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

Inducible Degradation of Target Proteins through a Tractable Affinity-Directed Protein Missile System

1
1. scibot 17 Sep 2020
  
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  DOI: 10.1016/j.chembiol.2020.06.013
  
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pubmed.ncbi.nlm.nih.gov/32668203/
Nov 2018
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Single-Molecule Analysis Reveals Linked Cycles of RSC Chromatin Remodeling and Ace1p Transcription Factor Binding in Yeast

1
1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S1097276518307561
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An Endothelial-to-Adipocyte Extracellular Vesicle Axis Governed by Metabolic State

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S0092867418311772
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Sense-Antisense lncRNA Pair Encoded by Locus 6p22.3 Determines Neuroblastoma Susceptibility via the USP36-CHD7-SOX9 Regulatory Axis

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S1535610818300205
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Oncogenic Role of THOR, a Conserved Cancer/Testis Long Non-coding RNA

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S0092867417314307
Nov 2017
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A Single-Cell Biochemistry Approach Reveals PAR Complex Dynamics during Cell Polarization

1
1. scibot 08 Nov 2017
  
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sciencedirect.com/science/article/pii/S1534580717306007
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β-TrCP1 Is a Vacillatory Regulator of Wnt Signaling

1
1. scibot 08 Nov 2017
  
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  AB_713650
  
  Curator: @chewbeccax
  
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sciencedirect.com/science/article/pii/S2451945617302234
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Development of Peptidomimetic Inhibitors of the ERG Gene Fusion Product in Prostate Cancer

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1. scibot 08 Nov 2017
  
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  AB_713650
  
  Curator: @kaitlinsung
  
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sciencedirect.com/science/article/pii/S1535610817300600
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A Force-Induced Directional Switch of a Molecular Motor Enables Parallel Microtubule Bundle Formation

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1. scibot 08 Nov 2017
  
  in Public
  
  AB_713650
  
  Curator: @chewbeccax
  
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  (Promega Cat# G9281, RRID:AB_713650)
  
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