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NicheSphere reveals an Spp1-centered multicellular niche in myeloproliferative neoplasm-associated fibrosis

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1. scibot 16 Oct 2026
  
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  DOI: 10.1016/j.cpblue.2026.100146
  
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sciencedirect.com/science/article/pii/S3051383926001441
Sep 2026
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CD4 T cells convert transient responses to KRAS inhibition to durable remissions in pancreatic cancer

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1. scibot 27 Sep 2026
  
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  DOI: 10.1016/j.cell.2026.08.045
  
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sciencedirect.com/science/article/pii/S0092867426010184
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Alox15 restrains glycolysis to support M2 macrophage effector function during helminth immunity

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1. scibot 24 Sep 2026
  
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  DOI: 10.1084/jem.20241620
  
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dx.doi.org/10.1084/jem.20241620
Aug 2026
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Spatial profiling of the spleen in mouse and human myelofibrosis reveals complement-driven immune-stromal interactions as a therapeutic target

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1. scibot 28 Aug 2026
  
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  DOI: 10.1016/j.stem.2026.07.012
  
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sciencedirect.com/science/article/pii/S1934590926002729
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A host-adapted commensal fungus from pet store mice drives type 2 immunity and cross-kingdom protection

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1. scibot 12 Aug 2026
  
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  DOI: 10.1016/j.isci.2026.117169
  
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sciencedirect.com/science/article/pii/S2589004226025472
Jul 2026
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Tryptophan degradation by intestinal Bacteroides induces anti-tumor immunity and limits melanoma growth

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1. scibot 15 Jul 2026
  
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  DOI: 10.1016/j.xcrm.2026.102921
  
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sciencedirect.com/science/article/pii/S2666379126003381
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SPP1+ Neutrophils Mediate Resistance to lmmune Checkpoint Blockade in BAP1-Inactivated Tumors

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1. scibot 11 Jul 2026
  
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  DOI: 10.1158/0008-5472.CAN-24-4962
  
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aacrjournals.org/cancerres/article/85/22/4433/767080/SPP1-Neutrophils-Mediate-Resistance-to-Immune
Jun 2026
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Chronic stress unleashes an intratumor phage-fibroblast-B cell circuit to promote tumor growth

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1. scibot 26 Jun 2026
  
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  DOI: 10.1016/j.ccell.2026.06.004
  
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sciencedirect.com/science/article/pii/S1535610826002916
May 2026
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Dendritic cell redundancy enables priming of anti-tumor CD4+ T cells in pancreatic cancer

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1. scibot 08 May 2026
  
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  DOI: 10.1016/j.ccell.2026.04.005
  
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sciencedirect.com/science/article/pii/S1535610826002163
Mar 2026
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Immunogenic tumor cell death and T-cell-derived IFN-γ elicit tumoricidal macrophages to potentiate OX40 immunotherapy

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1. scibot 27 Mar 2026
  
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  DOI: 10.1016/j.xcrm.2026.102699
  
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sciencedirect.com/science/article/pii/S2666379126001163
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In vivo evolution of antibody CR3022 expands cross-neutralization of SARS-CoV-2 variants and informs pan-sarbecovirus immunity

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1. scibot 24 Mar 2026
  
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  DOI: 10.1016/j.celrep.2026.117137
  
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sciencedirect.com/science/article/pii/S2211124726002159
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IL-4 treatment induces apoptosis of blood monocytes and proliferation of recruited injury-associated macrophages to resolve liver injury

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1. scibot 24 Mar 2026
  
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  DOI: 10.1016/j.celrep.2026.117136
  
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sciencedirect.com/science/article/pii/S2211124726002147
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Immune cells regulate circulating adipocyte extracellular vesicle levels in response to metabolic shifts

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1. scibot 17 Mar 2026
  
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  DOI: 10.1016/j.cmet.2026.02.008
  
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sciencedirect.com/science/article/pii/S1550413126000513
Feb 2026
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Endogenous retrovirus-derived RNA-DNA hybrids induce microglial synaptic pruning in autism models

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1. scibot 26 Feb 2026
  
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  DOI: 10.1016/j.neuron.2026.01.011
  
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sciencedirect.com/science/article/pii/S0896627326000127
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Autoimmune neuroinflammation leads to neuronal death via MIF nuclease-mediated parthanatos

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1. scibot 24 Feb 2026
  
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  DOI: 10.1038/s41593-026-02201-7
  
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nature.com/articles/s41593-026-02201-7
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Programmable iPSC-derived CAR-NK vesicles remodel the immune microenvironment and eradicate tumors

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1. scibot 06 Feb 2026
  
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  DOI: 10.1016/j.xcrm.2025.102545
  
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sciencedirect.com/science/article/pii/S2666379125006184
Jan 2026
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Nat10-mediated ac4C epitranscriptomics orchestrates hematopoietic stem/progenitor cell fate determination via translation control

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1. scibot 15 Jan 2026
  
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  DOI: 10.1126/sciadv.ady0301
  
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science.org/doi/10.1126/sciadv.ady0301
Dec 2025
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Gut microbiota promotes immune tolerance at the maternal-fetal interface

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1. scibot 18 Dec 2025
  
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  DOI: 10.1016/j.cell.2025.11.022
  
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sciencedirect.com:5037/science/article/pii/S0092867425013182
Nov 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The cutaneous response to a mosquito bite is influenced by the diurnal rhythm

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1. scibot 01 Nov 2025
  
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  DOI: 10.1016/j.isci.2025.113666
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12554125/
Sep 2025
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Systematic evaluation of GAPs and GEFs identifies a targetable dependency for hematopoietic malignancies

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1. scibot 16 Sep 2025
  
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  DOI: 10.1158/2159-8290.CD-25-0299
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12427560/
May 2025
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Vaccination against helminth IL-33 modulators permits immune-mediated parasite ejection

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1. scibot 17 May 2025
  
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  DOI: 10.1016/j.celrep.2025.115721
  
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sciencedirect.com/science/article/pii/S2211124725004929
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Myeloid-lineage-specific membrane protein LRRC25 suppresses immunity in solid tumor and is a potential cancer immunotherapy checkpoint target

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1. scibot 16 May 2025
  
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  DOI: 10.1016/j.celrep.2025.115631
  
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sciencedirect.com/science/article/pii/S2211124725004024
Apr 2025
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Single-cell and spatial transcriptomics reveal the pathogenesis of chronic granulomatous disease in a natural model

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1. scibot 24 Apr 2025
  
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  DOI: 10.1016/j.celrep.2025.115612
  
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sciencedirect.com/science/article/pii/S2211124725003833
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Reprogramming liver metastasis-associated macrophages toward an anti-tumoral phenotype through enforced miR-342 expression

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1. scibot 24 Apr 2025
  
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  DOI: 10.1016/j.celrep.2025.115592
  
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Targeting the dendritic cell-secreted immunoregulatory cytokine CCL22 alleviates radioresistance

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1. scibot 02 Apr 2025
  
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  DOI: 10.1158/1078-0432.CCR-23-3616
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11444901/
Jan 2025
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Myocarditis and neutrophil-mediated vascular leakage but not cytokine storm associated with fatal murine leptospirosis

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1. scibot 31 Jan 2025
  
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  DOI: 10.1016/j.ebiom.2025.105571
  
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sciencedirect.com/science/article/pii/S2352396425000155
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Progenitor effect in the spleen drives early recovery via universal hematopoietic cell inflation

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1. scibot 28 Jan 2025
  
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  DOI: 10.1016/j.celrep.2025.115241
  
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sciencedirect.com/science/article/pii/S2211124725000129
Nov 2024
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strobl-et-al-2024-jak-stat1-as-therapeutic-target-for-egfr-deficiency-associated-inflammation-and-scarring-alopecia-html.html

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1. scibot 14 Nov 2024
  
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  DOI: 10.1038/s44321-024-00166-3
  
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52.53.155.43/586ba8b525e8da6306112d5dd7635949084313ca/strobl-et-al-2024-jak-stat1-as-therapeutic-target-for-egfr-deficiency-associated-inflammation-and-scarring-alopecia-html.html
www.embopress.org www.embopress.org

JAK-STAT1 as therapeutic target for EGFR deficiency-associated inflammation and scarring alopecia

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1. scibot 14 Nov 2024
  
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  DOI: 10.1038/s44321-024-00166-3
  
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embopress.org/doi/10.1038/s44321-024-00166-3
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A modified BPaL regimen for tuberculosis treatment replaces linezolid with inhaled spectinamides

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1. scibot 07 Nov 2024
  
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  DOI: 10.7554/eLife.96190
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11460978/
Oct 2024
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CCL28 modulates neutrophil responses during infection with mucosal pathogens

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1. scibot 04 Oct 2024
  
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  DOI: 10.7554/eLife.78206
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11444682/
May 2024
www.biorxiv.org www.biorxiv.org

The Gut Microbiome Controls Liver Tumors via the Vagus Nerve

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1. scibot 09 May 2024
  
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  DOI: 10.1101/2024.01.23.576951
  
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biorxiv.org/content/10.1101/2024.01.23.576951v1
Apr 2024
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CD80 on skin stem cells promotes local expansion of regulatory T cells upon injury to orchestrate repair within an inflammatory environment

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1. scibot 30 Apr 2024
  
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  DOI: 10.1016/j.immuni.2024.04.003
  
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sciencedirect.com/science/article/pii/S1074761324002085
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A dopamine D1-like receptor-specific agonist improves the survival of septic mice

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1. scibot 18 Apr 2024
  
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  DOI: 10.1016/j.isci.2024.109587
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11016908/
Feb 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Dendritic Cells Overcome Cre/Lox Induced Gene Deficiency by Siphoning Cytosolic Material from Surrounding Cells

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1. scibot 28 Feb 2024
  
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  DOI: 10.1016/j.isci.2024.109119
  
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Scarring hair follicle destruction is driven by the collapse of EGFR-protected JAK-STAT1-sensitive stem cell immune privilege

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Suppression of adaptive NK cell expansion by macrophage-mediated phagocytosis inhibited by 2B4-CD48

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A time- and single-cell-resolved model of murine bone marrow hematopoiesis

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SON is an essential m6A target for hematopoietic stem cell fate

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A micro-electroporation/electrophoresis-based vaccine screening system reveals the impact of vaccination orders on cross-protective immunity

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Distinct Hypoxia-induced Translational Profiles of Embryonic and Adult-derived Macrophages

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ß1-adrenergic blockers preserve neuromuscular function by inhibiting the production of extracellular traps during systemic inflammation in mice

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Regulatory T cells require IL6 receptor alpha signaling to control skeletal muscle function and regeneration

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ALKBH5 modulates hematopoietic stem and progenitor cell energy metabolism through m6A modification-mediated RNA stability control

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Tumor-associated macrophages trigger MAIT cell dysfunction at the HCC invasive margin

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TSC22D3 as an immune-related prognostic biomarker for acute myeloid leukemia

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IGFBPL1 is a master driver of microglia homeostasis and resolution of neuroinflammation in glaucoma and brain tauopathy

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Controlling genetic heterogeneity in gene-edited hematopoietic stem cells by single-cell expansion

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YTHDF2 inhibition potentiates radiotherapy antitumor efficacy

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Dual IKZF2 and CK1α degrader targets acute myeloid leukemia cells

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IFNγ is a central node of cancer immune equilibrium

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Bispecific PD1-IL2v and anti-PD-L1 break tumor immunity resistance by enhancing stem-like tumor-reactive CD8+ T cells and reprogramming macrophages

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Mucosal exposure to non-tuberculous mycobacteria elicits B cell-mediated immunity against pulmonary tuberculosis

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The regional distribution of resident immune cells shapes distinct immunological environments along the murine epididymis

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Cbl-b Restrains Priming of Pathogenic Th17 Cells via the Inhibition of IL-6 Production by Macrophages

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1960-html.html

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Interleukin-27 signaling serves as an immunological checkpoint for innate cytotoxic cells to promote hepatocellular carcinoma

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During early stages of cancer, neutrophils initiate anti-tumor immune responses in tumor-draining lymph nodes

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Ex-Vivo Skin Explant Culture Is a Model for TSLP-Mediated Skin Barrier Immunity

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C/EBPδ-induced epigenetic changes control the dynamic gene transcription of S100a8 and S100a9

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Activation of the transcription factor NRF2 mediates the anti-inflammatory properties of a subset of over-the-counter and prescription NSAIDs

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Activating Mucosal-Associated Invariant T cells Induces a Broad Antitumor Response

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Interferon gamma constrains type 2 lymphocyte niche boundaries during mixed inflammation

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Inflammatory macrophages exploit unconventional pro-phagocytic integrins for phagocytosis and anti-tumor immunity

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Liver X receptors regulate natural killer T cell population and antitumor activity in the liver of mice

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6-Phosphogluconate dehydrogenase (6PGD), a key checkpoint in reprogramming of regulatory T cells metabolism and function

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Selective loss of resident macrophage-derived insulin-like growth factor-1 abolishes adaptive cardiac growth to stress

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Untitled document

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IKZF2 Drives Leukemia Stem Cell Self-Renewal and Inhibits Myeloid Differentiation

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An Interleukin-23-Interleukin-22 Axis Regulates Intestinal Microbial Homeostasis to Protect from Diet-Induced Atherosclerosis

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Stk24 protects against obesity-associated metabolic disorders by disrupting the NLRP3 inflammasome

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Suppressive neutrophils require PIM1 for metabolic fitness and survival during chronic viral infection

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Adiponectin preserves metabolic fitness during aging

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m6A Modification Prevents Formation of Endogenous Double-Stranded RNAs and Deleterious Innate Immune Responses during Hematopoietic Development

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Legionella-Infected Macrophages Engage the Alveolar Epithelium to Metabolically Reprogram Myeloid Cells and Promote Antibacterial Inflammation

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Rewilding Nod2 and Atg16l1 Mutant Mice Uncovers Genetic and Environmental Contributions to Microbial Responses and Immune Cell Composition

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A helminth-derived suppressor of ST2 blocks allergic responses

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A Stat6/Pten Axis Links Regulatory T Cells with Adipose Tissue Function

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Altered Immunity of Laboratory Mice in the Natural Environment Is Associated with Fungal Colonization

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Pulsatile MEK Inhibition Improves Anti-tumor Immunity and T Cell Function in Murine Kras Mutant Lung Cancer

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The Cardiac Microenvironment Instructs Divergent Monocyte Fates and Functions in Myocarditis

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Untitled document

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Untitled document

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Untitled document

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SYK-CARD9 Signaling Axis Promotes Gut Fungi-Mediated Inflammasome Activation to Restrict Colitis and Colon Cancer

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LAG-3 Inhibitory Receptor Expression Identifies Immunosuppressive Natural Regulatory Plasma Cells

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A Lipoylated Metabolic Protein Released by Staphylococcus aureus Suppresses Macrophage Activation

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CD150high Bone Marrow Tregs Maintain Hematopoietic Stem Cell Quiescence and Immune Privilege via Adenosine

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CRIg, a tissue-resident macrophage specific immune checkpoint molecule, promotes immunological tolerance in NOD mice, via a dual role in effector and regulatory T cells

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Granulocyte-Monocyte Progenitors and Monocyte-Dendritic Cell Progenitors Independently Produce Functionally Distinct Monocytes

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A Stat6/Pten Axis Links Regulatory T Cells with Adipose Tissue Function

1
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Dissecting Immune Circuits by Linking CRISPR-Pooled Screens with Single-Cell RNA-Seq

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