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    Pharmacological antagonism of HTR2B reduces ERK and STAT3 activation and prevents renal fibrosis during the development of Adenine-Induced CKD in rats
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  3. Sep 2026
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    Targeted phagocytosis of TNF-α by CAR macrophages restores immune homeostasis in arthritis
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  5. Jun 2026
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    Mume Flos ameliorates MASLD-associated cognitive impairment by attenuating IL-17/NF-κB-mediated metabolic neuroinflammation
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    MCC950 suppresses NLRP3-dependent neuroinflammation and ameliorates cognitive decline in a rat model of cerebral small vessel disease
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    Genistein-3’-sodium sulfonate improves neuroinflammation, blood-brain barrier function, and microglial activation after chronic cerebral hypoperfusion by regulating TGR5
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  11. Mar 2026
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    5-hydroxytryptamine 2B Receptor Antagonism Restores ATP and Reduces Tubulointerstitial Fibrosis in the Renal Cortices of Aged Mice
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    NPC2 suppresses osteolytic metastasis in lung adenocarcinoma via the AKT/mTOR pathway and tumor-osteoclast crosstalk
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  14. Jan 2026
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    Senloytics, dasatinib plus quercetin, reduce kidney inflammation, senescent cell abundance, and injury while restoring geroprotective factors in murine diabetic kidney disease
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    A Novel TLR4 Inhibitor DB03476 Rescued Renal Inflammation in Acute Kidney Injury Model
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    CCL5 deficiency aggravates acute DSS-induced colitis by restricting IL-33-induced formation of Tregs in intestinal tract
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    Enhanced non-enzymatic H2S generation extends lifespan and healthspan in male mice
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    Protective effects of alkaloidal fraction of Elaeocarpus angustifolius Blume against AlCl₃-evoked neurotoxicity: insights from an in vivo model of Alzheimer’s disease
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  29. Jun 2025
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    Exosomal encapsulation of a steviol derivative SD9 to overcome TRAIL resistance as a highly effective therapy against lung cancer
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    Histone acetylation alteration by KAT6A inhibitor WM-1119 suppresses IgE-mediated mast cell activation and allergic inflammation via reduction in AP-1 signaling
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  40. Jul 2024
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    Therapeutic targeting of immunometabolism reveals a critical reliance on hexokinase 2 dosage for microglial activation and Alzheimer’s progression
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  45. Dec 2023
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    NSC48160 targets AMPKα to ameliorate nonalcoholic steatohepatitis by inhibiting lipogenesis and mitochondrial oxidative stress
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  47. Oct 2023
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  49. Jul 2023
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    Targeting phenylpyruvate restrains excessive NLRP3 inflammasome activation and pathological inflammation in diabetic wound healing
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  51. Jun 2023
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  53. May 2023
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    SYTL5 promotes papillary thyroid carcinoma progression by enhancing activation of the NF-κB signaling pathway
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  57. Dec 2022
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    Morusin Protected Ruminal Epithelial Cells against Lipopolysaccharide-Induced Inflammation through Inhibiting EGFR-AKT/NF-κB Signaling and Improving Barrier Functions
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  59. Sep 2022
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    Alpha-Momorcharin Inhibits Proinflammatory Cytokine Expression by M1 Macrophages but Not Anti-Inflammatory Cytokine Expression by M2 Macrophages
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  61. Aug 2022
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    Aerobic glycolysis promotes tumor immune evasion by hexokinase2-mediated phosphorylation of IκBα
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  63. Jul 2022
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    MicroRNA-22-3p ameliorates Alzheimer’s disease by targeting SOX9 through the NF-κB signaling pathway in the hippocampus
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  65. Aug 2021
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  67. Jul 2021
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    Inhibiting Brd4 alleviated PTSD-like behaviors and fear memory through regulating immediate early genes expression and neuroinflammation in rats
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  69. Jun 2021
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  71. Apr 2021
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    Optogenetic activation of spinal microglia triggers chronic pain in mice
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  73. Sep 2020
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    Resolvin D1 Modulates the Intracellular VEGF-Related miRNAs of Retinal Photoreceptors Challenged With High Glucose
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  75. Nov 2018
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    The GABAA Receptor α2 Subunit Activates a Neuronal TLR4 Signal in the Ventral Tegmental Area that Regulates Alcohol and Nicotine Abuse
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    Nicotinamide Improves Aspects of Healthspan, but Not Lifespan, in Mice
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    Innately activated TLR4 signal in the nucleus accumbens is sustained by CRF amplification loop and regulates impulsivity
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  80. Nov 2017
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    Caspase-8 contributes to angiogenesis and chemotherapy resistance in glioblastoma
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