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Innate sensor responses set a supra-unitary threshold for viral replication

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1. scibot 05 Nov 2026
  
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  RRID:AB_777310
  
  DOI: 10.1016/j.cell.2026.10.004
  
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sciencedirect.com/science/article/pii/S0092867426012158
Oct 2026
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STING engages PKR to drive lysosomal cell death in lung ischemia-reperfusion injury

1
1. scibot 15 Oct 2026
  
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  RRID:AB_777310
  
  DOI: 10.1016/j.molcel.2026.09.024
  
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sciencedirect.com/science/article/pii/S1097276526006672
Aug 2026
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PKR engages viral RNA and intron-retained host transcripts during poxvirus infection

1
1. scibot 10 Aug 2026
  
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  RRID:AB_777310
  
  DOI: 10.1016/j.celrep.2026.117838
  
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sciencedirect.com/science/article/pii/S2211124726009162
Dec 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

ZYS-1 is not an ADAR1 inhibitor

1
1. scibot 02 Dec 2025
  
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  RRID:AB_777310
  
  DOI: 10.1261/rna.080721.125
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12621589/
Nov 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

PACT suppresses PKR activation through dsRNA binding and dimerization, and is a therapeutic target for triple-negative breast cancer

1
1. scibot 23 Nov 2025
  
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  RRID:AB_777310
  
  DOI: 10.1261/rna.080637.125
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12530129/
Sep 2025
52.53.155.43 52.53.155.43

2025.09.04.674332v2.full-html.html

1
1. scibot 18 Sep 2025
  
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  AB_777310
  
  DOI: 10.1101/2025.09.04.674332
  
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52.53.155.43/304402c0b5b5e8844bb324b2732dfcb1e481f20c/2025.09.04.674332v2.full-html.html
Aug 2025
www.biorxiv.org www.biorxiv.org

ZYS-1 is not an ADAR1 inhibitor

1
1. scibot 13 Aug 2025
  
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  RRID:AB_777310
  
  DOI: 10.1101/2025.08.08.669362
  
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biorxiv.org/content/10.1101/2025.08.08.669362v2
May 2025
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A multimodal screening platform for endogenous dipeptide repeat proteins in C9orf72 patient iPSC neurons

1
1. scibot 17 May 2025
  
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  RRID:AB_777310
  
  DOI: 10.1016/j.celrep.2025.115695
  
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sciencedirect.com/science/article/pii/S2211124725004668
Apr 2025
onlinelibrary.wiley.com onlinelibrary.wiley.com

Interferon-Inducible ADAR1 p150 Is Essential for the Survival of Oral Squamous Cell Carcinoma

1
1. scibot 01 Apr 2025
  
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  RRID: AB_777310
  
  DOI: 10.1002/mc.23910
  
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onlinelibrary.wiley.com/doi/10.1002/mc.23910
Feb 2025
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HSPA8 dampens SCAP/INSIG split and SREBP activation by reducing PKR-mediated INSIG phosphorylation

1
1. scibot 20 Feb 2025
  
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  RRID:AB_777310
  
  DOI: 10.1016/j.celrep.2025.115339
  
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sciencedirect.com/science/article/pii/S221112472500110X
Dec 2024
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RNA sensing induced by chromosome missegregation augments anti-tumor immunity

1
1. scibot 21 Dec 2024
  
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  RRID:AB_777310
  
  DOI: 10.1016/j.molcel.2024.11.025
  
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sciencedirect.com/science/article/pii/S109727652400950X
Aug 2024
cellandbioscience.biomedcentral.com cellandbioscience.biomedcentral.com

β-adrenergic receptor inhibition enhances oncolytic herpes virus propagation through STAT3 activation in gastric cancer

1
1. scibot 02 Aug 2024
  
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  32036
  
  DOI: 10.1186/s13578-021-00687-1
  
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  RRID:AB_777310 RRIDCUR:Missing
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cellandbioscience.biomedcentral.com/articles/10.1186/s13578-021-00687-1
May 2024
www.biorxiv.org www.biorxiv.org

Activation of PKR by a short-hairpin RNA

1
1. scibot 17 May 2024
  
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  RRID:AB_777310
  
  DOI: 10.1101/2024.05.08.592371
  
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biorxiv.org/content/10.1101/2024.05.08.592371v1
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Atherosis-associated lnc_000048 activates PKR to enhance STAT1-mediated polarization of THP-1 macrophages to M1 phenotype

1
1. scibot 15 May 2024
  
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  RRID:AB_777310
  
  DOI: 10.4103/NRR.NRR-D-23-01355
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11090429/
Apr 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Induction of Viral Mimicry Upon Loss of DHX9 and ADAR1 in Breast Cancer Cells

1
1. scibot 10 Apr 2024
  
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  RRID:AB_777310
  
  DOI: 10.1158/2767-9764.CRC-23-0488
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10993856/
Jan 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

XRN1 deletion induces PKR-dependent cell lethality in interferon-activated cancer cells

1
1. scibot 23 Jan 2024
  
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  RRID:AB_777310
  
  DOI: 10.1016/j.celrep.2023.113600
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10989277/
Oct 2023
www.sciencedirect.com www.sciencedirect.com

ADAR1p150 prevents MDA5 and PKR activation via distinct mechanisms to avert fatal autoinflammation

1
1. scibot 14 Oct 2023
  
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  RRID:AB_777310
  
  DOI: 10.1016/j.molcel.2023.09.018
  
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sciencedirect.com/science/article/abs/pii/S1097276523007402
Sep 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Viral sensing by epithelial cells involves PKR- and caspase-3-dependent generation of gasdermin E pores

1
1. scibot 08 Sep 2023
  
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  AB_777310
  
  DOI: 10.1016/j.isci.2023.107698
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10480325/
Jul 2023
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Optogenetic control of the integrated stress response reveals proportional encoding and the stress memory landscape

1
1. scibot 21 Jul 2023
  
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  RRID:AB_777310
  
  DOI: 10.1016/j.cels.2023.06.001
  
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sciencedirect.com/science/article/abs/pii/S2405471223001540
Jun 2023
dx.doi.org dx.doi.org

LINC00886 negatively regulates the malignancy in anaplastic thyroid cancer

1
1. scibot 21 Jun 2023
  
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  RRID:AB_777310
  
  DOI: 10.1210/endocr/bqac204
  
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dx.doi.org/10.1210/endocr/bqac204
Apr 2023
www.sciencedirect.com www.sciencedirect.com

VMP1 affects endoplasmic reticulum stress sensitivity via differential modulation of the three unfolded protein response arms

1
1. scibot 20 Apr 2023
  
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  RRID:AB_777310
  
  DOI: 10.1016/j.celrep.2023.112209
  
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sciencedirect.com/science/article/pii/S2211124723002206
Jan 2023
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PKR deficiency delays vascular aging via inhibiting GSDMD-mediated endothelial cell hyperactivation

2
1. scibot 12 Jan 2023
  
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  RRID:AB_777310
  
  DOI: 10.1016/j.isci.2022.105909
  
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2. scibot 12 Jan 2023
  
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  RRID:AB_777310
  
  DOI: 10.1016/j.isci.2022.105909
  
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sciencedirect.com/science/article/pii/S2589004222021824
Aug 2022
www.sciencedirect.com www.sciencedirect.com

Mitochondrial double-stranded RNAs govern the stress response in chondrocytes to promote osteoarthritis development

1
1. scibot 10 Aug 2022
  
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  RRID:AB_777310
  
  DOI: 10.1016/j.celrep.2022.111178
  
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sciencedirect.com/science/article/pii/S2211124722009913
Aug 2021
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Exocyst protein subnetworks integrate Hippo and mTOR signaling to promote virus detection and cancer

1
1. scibot 06 Aug 2021
  
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  AB_777310
  
  DOI: 10.1016/j.celrep.2021.109491
  
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sciencedirect.com/science/article/pii/S2211124721009189
Jun 2021
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Vaccinia virus E3 prevents sensing of Z-RNA to block ZBP1-dependent necroptosis

1
1. scibot 30 Jun 2021
  
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  RRID:AB_777310
  
  DOI: 10.1016/j.chom.2021.05.009
  
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sciencedirect.com/science/article/pii/S1931312821002377
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SARS-CoV-2 infection induces beta cell transdifferentiation

1
1. scibot 05 Jun 2021
  
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  RRID:AB_777310
  
  DOI: 10.1016/j.cmet.2021.05.015
  
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sciencedirect.com/science/article/pii/S1550413121002321
Nov 2018
www.sciencedirect.com www.sciencedirect.com

Untitled document

1
1. scibot 05 Nov 2018
  
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  RRID:AB_777310
  
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sciencedirect.com/science/article/pii/S2211124718309550
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The TIA1 RNA-Binding Protein Family Regulates EIF2AK2-Mediated Stress Response and Cell Cycle Progression

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S1097276518300406
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Targeting Poxvirus Decapping Enzymes and mRNA Decay to Generate an Effective Oncolytic Virus

1
1. scibot 05 Nov 2018
  
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  phospho(T446)-PKR (Abcam # 32036).
  
  Curator: @evieth
  
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  (Abcam Cat# ab32036, RRID:AB_777310)
  
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  RRID:AB_777310 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S2372770518300019