32 Matching Annotations
  1. Jul 2024
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Influenza A virus infection activates STAT3 to enhance SREBP2 expression, cholesterol biosynthesis, and virus replication
    1
    1. scibot 19 Jul 2024
      AB_779079

      DOI: 10.1016/j.isci.2024.110424

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    ncbi.nlm.nih.gov/pmc/articles/PMC11301072/
  3. May 2024
  4. www.mdpi.com www.mdpi.com
    Presenilin Deficiency Results in Cellular Cholesterol Accumulation by Impairment of Protein Glycosylation and NPC1 Function
    1
    1. scibot 21 May 2024
      RRID:AB_779079

      DOI: 10.3390/ijms25105417

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    mdpi.com/1422-0067/25/10/5417
  5. 52.53.155.43 52.53.155.43
    Metabolic reprogramming of hypoxic tumour-associated macrophages through CSF-1R targeting favours treatment efficiency in colorectal cancers
    1
    1. scibot 16 May 2024
      AB_779079

      DOI: 10.1101/2024.02.22.581558

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    52.53.155.43/8391d5e75ba57c9ef8c1ebe0973fe3c1602760fc/2024.02.22.581558v3.full-html.html
  6. www.sciencedirect.com www.sciencedirect.com
    Small-molecule-induced epigenetic rejuvenation promotes SREBP condensation and overcomes barriers to CNS myelin regeneration
    1
    1. scibot 03 May 2024
      RRID:AB_779079

      DOI: 10.1016/j.cell.2024.04.005

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    sciencedirect.com/science/article/pii/S0092867424004008
  7. Feb 2024
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ferredoxin 1 is essential for embryonic development and lipid homeostasis
    1
    1. scibot 08 Feb 2024
      RRID:AB_779079

      DOI: 10.7554/eLife.91656

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    ncbi.nlm.nih.gov/pmc/articles/PMC10846857/
  9. Dec 2023
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of lipid synthesis by the HIV integrase strand transfer inhibitor elvitegravir in primary rat oligodendrocyte cultures
    1
    1. scibot 28 Dec 2023
      RRID:AB_779079

      DOI: 10.3389/fnmol.2023.1323431

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    ncbi.nlm.nih.gov/pmc/articles/PMC10749327/
  11. Oct 2023
  12. www.embopress.org www.embopress.org
    Hypoxia activates SREBP2 through Golgi disassembly in bone marrow-derived monocytes for enhanced tumor growth
    1
    1. scibot 03 Oct 2023
      RRID:AB_779079

      DOI: 10.15252/embj.2023114032

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    embopress.org/doi/10.15252/embj.2023114032
  13. Sep 2023
  14. journals.physiology.org journals.physiology.org
    CircFOXN2 alleviates glucocorticoid- and tacrolimus-induced dyslipidemia by reducing FASN mRNA stability by binding to PTBP1 during liver transplantation
    1
    1. scibot 15 Sep 2023
      RRID:AB_779079

      DOI: 10.1152/ajpcell.00462.2022

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    journals.physiology.org/doi/10.1152/ajpcell.00462.2022
  15. www.sciencedirect.com www.sciencedirect.com
    Characterization of an in vitro steatosis model simulating activated de novo lipogenesis in MAFLD patients
    1
    1. scibot 07 Sep 2023
      RRID:AB_779079

      DOI: 10.1016/j.isci.2023.107727

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    sciencedirect.com/science/article/pii/S2589004223018047
  16. Jul 2023
  17. 52.53.155.43 52.53.155.43
    cd-22-0411-html.html
    1
    1. scibot 01 Jul 2023
      RRID:AB_779079

      DOI: 10.1158/2159-8290.cd-22-0411

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    52.53.155.43/453457acda6208aed297e8061921a5c2d2ddddf2/cd-22-0411-html.html
  18. May 2023
  19. www.sciencedirect.com www.sciencedirect.com
    Exhaustion-associated cholesterol deficiency dampens the cytotoxic arm of antitumor immunity
    1
    1. scibot 27 May 2023
      RRID:AB_779079

      DOI: 10.1016/j.ccell.2023.04.016

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    sciencedirect.com/science/article/pii/S1535610823001423
  20. Dec 2022
  21. www.sciencedirect.com www.sciencedirect.com
    Tim-4 reprograms cholesterol metabolism to suppress antiviral innate immunity by disturbing the Insig1-SCAP interaction in macrophages
    1
    1. scibot 01 Dec 2022
      RRID:AB_779079

      DOI: 10.1016/j.celrep.2022.111738

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    sciencedirect.com/science/article/pii/S2211124722016163
  22. Aug 2022
  23. www.sciencedirect.com www.sciencedirect.com
    Activation of mitochondrial TRAP1 stimulates mitochondria-lysosome crosstalk and correction of lysosomal dysfunction
    1
    1. scibot 30 Aug 2022
      RRID:AB_779079

      DOI: 10.1016/j.isci.2022.104941

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    sciencedirect.com/science/article/pii/S2589004222012135
  24. www.sciencedirect.com www.sciencedirect.com
    PIDDosome-SCAP crosstalk controls high-fructose-diet-dependent transition from simple steatosis to steatohepatitis
    1
    1. scibot 30 Aug 2022
      RRID:AB_779079

      DOI: 10.1016/j.cmet.2022.08.005

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    sciencedirect.com/science/article/pii/S1550413122003485
  25. Jun 2022
  26. www.sciencedirect.com www.sciencedirect.com
    Cholesterol and matrisome pathways dysregulated in astrocytes and microglia
    1
    1. scibot 24 Jun 2022
      RRID:AB_779079

      DOI: 10.1016/j.cell.2022.05.017

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    sciencedirect.com/science/article/pii/S0092867422006481
  27. Sep 2021
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hepatocyte activity of the cholesterol sensor smoothened regulates cholesterol and bile acid homeostasis in mice
    1
    1. scibot 28 Sep 2021
      RRID:AB_779079

      DOI: 10.1016/j.isci.2021.103089

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    ncbi.nlm.nih.gov/pmc/articles/PMC8449244/
  29. Jul 2021
  30. www.nature.com www.nature.com
    Tonic prime-boost of STING signalling mediates Niemann–Pick disease type C
    1
    1. scibot 31 Jul 2021
      ab30682

      DOI: 10.1038/s41586-021-03762-2

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    nature.com/articles/s41586-021-03762-2
  31. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    1. scibot 31 Jul 2021
      RRID:AB_779079

      DOI: 10.1016/j.cell.2018.11.011

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    sciencedirect.com/science/article/pii/S0092867418315034
  32. www.sciencedirect.com www.sciencedirect.com
    Cholesterol Homeostatic Regulator SCAP-SREBP2 Integrates NLRP3 Inflammasome Activation and Cholesterol Biosynthetic Signaling in Macrophages
    1
    1. scibot 30 Jul 2021
      RRID:AB_779079

      DOI: 10.1016/j.immuni.2018.08.021

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      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S1074761318303844
  33. www.sciencedirect.com www.sciencedirect.com
    ERAD components Derlin-1 and Derlin-2 are essential for postnatal brain development and motor function
    1
    1. scibot 21 Jul 2021
      RRID:AB_779079

      DOI: 10.1016/j.isci.2021.102758

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    sciencedirect.com/science/article/pii/S2589004221007264
  34. Jun 2021
  35. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Activation of nuclear receptor PXR induces atherogenic lipids and PCSK9 through SREBP2‐mediated mechanism
    1
    1. scibot 25 Jun 2021
      RRID:AB_779079

      DOI: 10.1111/bph.15433

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15433
  36. May 2021
  37. www.cell.com www.cell.com
    TMEM41B acts as an ER scramblase required for lipoprotein biogenesis and lipid homeostasis
    1
    1. scibot 20 May 2021
      Rabbit anti-SREBP2

      DOI: 10.1016/j.cmet.2021.05.006

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      Curator: @Naa003

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      RRID:AB_779079 RRIDCUR:Missing
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    cell.com/cell-metabolism/fulltext/S1550-4131(21)00223-0
  38. www.sciencedirect.com www.sciencedirect.com
    The ZMYND8-regulated mevalonate pathway endows YAP-high intestinal cancer with metabolic vulnerability
    1
    1. scibot 01 May 2021
      RRID:AB_779079

      DOI: 10.1016/j.molcel.2021.04.009

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    sciencedirect.com/science/article/pii/S1097276521003142
  39. Apr 2021
  40. www.sciencedirect.com www.sciencedirect.com
    Cholesterol Pathway Inhibition Induces TGF-β Signaling to Promote Basal Differentiation in Pancreatic Cancer
    1
    1. scibot 22 Apr 2021
      RRID:AB_779079

      DOI: 10.1016/j.ccell.2020.08.015

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    sciencedirect.com/science/article/pii/S1535610820304268
  41. Sep 2020
  42. www.sciencedirect.com www.sciencedirect.com
    Maintaining Iron Homeostasis Is the Key Role of Lysosomal Acidity for Cell Proliferation
    1
    1. scibot 03 Sep 2020
      RRID: AB_779079

      DOI: 10.1016/j.molcel.2020.01.003

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      Curator: @ethanbadger

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    sciencedirect.com/science/article/pii/S1097276520300034
  43. Jan 2020
  44. www.sciencedirect.com www.sciencedirect.com
    The Cytokine TNF Promotes Transcription Factor SREBP Activity and Binding to Inflammatory Genes to Activate Macrophages and Limit Tissue Repair
    1
    1. scibot 13 Jan 2020
      RRID:AB_779079

      DOI: 10.1016/j.immuni.2019.06.005

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      RRID:AB_779079 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1074761319302754
  45. www.sciencedirect.com www.sciencedirect.com
    SIRT6 Promotes Hepatic Beta-Oxidation via Activation of PPARα
    1
    1. scibot 13 Jan 2020
      RRID:AB_779079

      DOI: 10.1016/j.celrep.2019.11.067

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    sciencedirect.com/science/article/pii/S221112471931558X
  46. www.sciencedirect.com www.sciencedirect.com
    GPR146 Deficiency Protects against Hypercholesterolemia and Atherosclerosis
    1
    1. scibot 13 Jan 2020
      RRID:AB_779079

      DOI: 10.1016/j.cell.2019.10.034

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    sciencedirect.com/science/article/pii/S0092867419312115
  47. academic.oup.com academic.oup.com
    Intestine-Specific Overexpression of LDLR Enhances Cholesterol Excretion and Induces Metabolic Changes in Male Mice
    1
    1. scibot 13 Jan 2020
      RRID:AB_779079

      DOI: 10.1210/en.2018-00098

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      RRID:AB_779079 RRIDCUR:Validated
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    academic.oup.com/endo/article/160/4/744/5251728
  48. Nov 2018
  49. www.sciencedirect.com www.sciencedirect.com
    ER Stress Drives Lipogenesis and Steatohepatitis via Caspase-2 Activation of S1P
    1
    1. scibot 05 Nov 2018
      RRID:AB_779079

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S0092867418310365
  50. www.sciencedirect.com www.sciencedirect.com
    Citrobacter rodentium Subverts ATP Flux and Cholesterol Homeostasis in Intestinal Epithelial Cells In Vivo
    2
    1. scibot 05 Nov 2018
      RRID:AB_779079

      Curator: @evieth

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    2. scibot 05 Nov 2018
      RRID:AB_779079

      Curator: @evieth

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    sciencedirect.com/science/article/pii/S1550413117305545