176 Matching Annotations
  1. Last 7 days
  2. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    A novel inhibitor of class IIa histone deacetylases attenuates collagen-induced arthritis
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    1. scibot 27 Sep 2024
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      DOI: 10.1111/bph.17306

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.17306
  3. www.sciencedirect.com www.sciencedirect.com
    Redox-dependent condensation and cytoplasmic granulation by human ssDNA-binding protein-1 delineate roles in oxidative stress response
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    sciencedirect.com/science/article/pii/S2589004224020133
  4. Sep 2024
  5. 52.53.155.43 52.53.155.43
    Human iPSC-derived myelinating organoids and globoid cells to study Krabbe Disease
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    1. scibot 05 Sep 2024
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      DOI: 10.1101/2024.07.19.604372

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    52.53.155.43/094bf1894e7037610818c8319cb16bd0730a5b11/2024.07.19.604372v1.full-html.html
  6. Aug 2024
  7. www.biorxiv.org www.biorxiv.org
    Ferroptosis susceptibility of melanoma cells: dependence on cell-type, acquired drug resistance, and medium composition
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    1. scibot 22 Aug 2024
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    biorxiv.org/content/10.1101/2024.08.12.607529v1
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    Mutant TP53 switches therapeutic vulnerability during gastric cancer progression within interleukin-6 family cytokines
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    1. scibot 21 Aug 2024
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    sciencedirect.com/science/article/pii/S2211124724009665
  9. www.embopress.org www.embopress.org
    1,10-phenanthroline inhibits sumoylation and reveals that yeast SUMO modifications are highly transient
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    1. scibot 13 Aug 2024
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      DOI: 10.1038/s44319-023-00010-8

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    embopress.org/doi/full/10.1038/s44319-023-00010-8
  10. Jul 2024
  11. www.cell.com www.cell.com
    Regulation of the DLC3 tumor suppressor by a novel phosphoswitch
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    cell.com/iscience/abstract/S2589-0042(24)01428-7
  12. www.cell.com www.cell.com
    SigmaR1 shapes rough endoplasmic reticulum membrane sheets
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    1. scibot 12 Jul 2024
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      DOI: 10.1016/j.devcel.2024.06.005

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    cell.com/developmental-cell/fulltext/S1534-5807(24)00382-4
  13. Jun 2024
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Exocyst Complex is Required for the Trafficking and Delivery of KCa3.1 to the Basolateral Membrane of Polarized Epithelia
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    1. scibot 07 Jun 2024
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      DOI: 10.1152/ajpcell.00374.2022

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    ncbi.nlm.nih.gov/pmc/articles/PMC10243536/
  15. 52.53.155.43 52.53.155.43
    elife-90203-v1-html.html
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    1. scibot 06 Jun 2024
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      DOI: 10.7554/elife.90203

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      DOI: 10.7554/elife.90203

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  16. May 2024
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Local glycolysis fuels actomyosin contraction during axonal retraction
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    1. scibot 03 May 2024
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      DOI: 10.1083/jcb.202206133

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    ncbi.nlm.nih.gov/pmc/articles/PMC10616508/
  18. Mar 2024
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Functional BRI2-TREM2 interactions in microglia: implications for Alzheimer's and related dementias
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    1. scibot 16 Mar 2024
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      DOI: 10.1038/s44319-024-00077-x

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    ncbi.nlm.nih.gov/pmc/articles/PMC10933458/
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Non-canonical isoforms of the mRNA polyadenylation factor WDR33 regulate STING-mediated immune responses
    2
    1. scibot 05 Mar 2024
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      DOI: 10.1016/j.celrep.2024.113886

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      DOI: 10.1016/j.celrep.2024.113886

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    ncbi.nlm.nih.gov/pmc/articles/PMC11019558/
  21. Feb 2024
  22. 52.53.155.43 52.53.155.43
    RAS isoform specific activities are disrupted by disease associated mutations during cell differentiation
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      DOI: 10.1101/2023.10.05.561021

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  23. 52.53.155.43 52.53.155.43
    Identification of an H-Ras nanocluster disrupting peptide
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      DOI: 10.1101/2023.09.07.556635

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      DOI: 10.1101/2023.09.07.556635

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    52.53.155.43/50febc729cb1f3f2f29f241e3592121bf7d8fba9/2023.09.07.556635v1.full-html.html
  24. 52.53.155.43 52.53.155.43
    An improved PDE6D inhibitor combines with Sildenafil to synergistically inhibit KRAS mutant cancer cell growth
    1
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      DOI: 10.1101/2023.08.23.554263

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  25. www.embopress.org www.embopress.org
    Functional BRI2-TREM2 interactions in microglia: implications for Alzheimer’s and related dementias
    1
    1. scibot 15 Feb 2024
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      DOI: 10.1038/s44319-024-00077-x

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    embopress.org/doi/10.1038/s44319-024-00077-x
  26. Jan 2024
  27. www.sciencedirect.com www.sciencedirect.com
    EXO1 protects BRCA1-deficient cells against toxic DNA lesions
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    1. scibot 25 Jan 2024
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      DOI: 10.1016/j.molcel.2023.12.039

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    sciencedirect.com/science/article/pii/S1097276523010857
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Frequent loss-of-function mutations in the AMPK-α2 catalytic subunit suggest a tumour suppressor role in human skin cancers
    1
    1. scibot 05 Jan 2024
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      DOI: 10.1042/BCJ20230380

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    ncbi.nlm.nih.gov/pmc/articles/PMC10754287/
  29. Dec 2023
  30. www.sciencedirect.com www.sciencedirect.com
    Needle biopsy accelerates pro-metastatic changes and systemic dissemination in breast cancer: Implications for mortality by surgery delay
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      DOI: 10.1016/j.xcrm.2023.101330

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    sciencedirect.com/science/article/pii/S2666379123005475
  31. www.sciencedirect.com www.sciencedirect.com
    MORG1 limits mTORC1 signaling by inhibiting Rag GTPases
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    sciencedirect.com/science/article/pii/S1097276523009681
  32. Oct 2023
  33. www.sciencedirect.com www.sciencedirect.com
    Blocking of ebolavirus spread through intercellular connections by an MPER-specific antibody depends on BST2/tetherin
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      DOI: 10.1016/j.celrep.2023.113254

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    sciencedirect.com/science/article/pii/S2211124723012664
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Modification of Lysine-260 2-hydroxyisobutyrylation destabilizes ALDH1A1 expression to regulate bladder cancer progression
    1
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      DOI: 10.1016/j.isci.2023.108142

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    ncbi.nlm.nih.gov/pmc/articles/PMC10585400/
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Non-Psychoactive Phytocannabinoids Inhibit Inflammation-Related Changes of Human Coronary Artery Smooth Muscle and Endothelial Cells
    1
    1. scibot 18 Oct 2023
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      DOI: 10.3390/cells12192389

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    ncbi.nlm.nih.gov/pmc/articles/PMC10571842/
  36. 52.53.155.43 52.53.155.43
    BRI2-mediated regulation of TREM2 processing in microglia and its potential implications for Alzheimer’s disease and related dementias
    1
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      DOI: 10.1101/2023.06.14.544924

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    52.53.155.43/5afe577c269e488702b5f7086020251c9f5e047d/2023.06.14.544924v1.full-html.html
  37. www.sciencedirect.com www.sciencedirect.com
    SARS-CoV-2 hampers dopamine production in iPSC-derived dopaminergic neurons
    1
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      DOI: 10.1016/j.yexmp.2023.104874

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    sciencedirect.com/science/article/pii/S0014480023000254
  38. Sep 2023
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Splicing regulation of GFPT1 muscle-specific isoform and its roles in glucose metabolisms and neuromuscular junction
    1
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      DOI: 10.1016/j.isci.2023.107746

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    ncbi.nlm.nih.gov/pmc/articles/PMC10514471/
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The MORC2 p.S87L mutation reduces proliferation of pluripotent stem cells derived from a patient with the spinal muscular atrophy-like phenotype by inhibiting proliferation-related signaling pathways
    1
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      DOI: 10.4103/1673-5374.375347

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    ncbi.nlm.nih.gov/pmc/articles/PMC10479865/
  41. Aug 2023
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CD31 signaling promotes the detachment at the uropod of extravasating neutrophils allowing their migration to sites of inflammation
    1
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      DOI: 10.7554/eLife.84752

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    ncbi.nlm.nih.gov/pmc/articles/PMC10431918/
  43. link.springer.com link.springer.com
    Acetylation of p53 in the Cerebral Cortex after Photothrombotic Stroke
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      DOI: 10.1007/s12975-023-01183-z

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    link.springer.com/article/10.1007/s12975-023-01183-z
  44. elifesciences.org elifesciences.org
    Promoting axon regeneration by inhibiting RNA N6-methyladenosine demethylase ALKBH5
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      DOI: 10.7554/eLife.85309

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    elifesciences.org/articles/85309
  45. Jul 2023
  46. www.sciencedirect.com www.sciencedirect.com
    Genome-scale mapping of DNA damage suppressors through phenotypic CRISPR-Cas9 screens
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      DOI: 10.1016/j.molcel.2023.06.025

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    sciencedirect.com/science/article/pii/S1097276523004720
  47. Jun 2023
  48. www.sciencedirect.com www.sciencedirect.com
    High-throughput longitudinal electrophysiology screening of mature chamber-specific hiPSC-CMs using optical mapping
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      DOI: 10.1016/j.isci.2023.107142

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    sciencedirect.com/science/article/pii/S2589004223012191
  49. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Characterizing microglial senescence: Tau as a key player
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    1. scibot 08 Jun 2023
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      DOI: 10.1111/jnc.15866

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15866
  50. Apr 2023
  51. www.sciencedirect.com www.sciencedirect.com
    Glutamylation of an HIV-1 protein inhibits the immune response by hijacking STING
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      DOI: 10.1016/j.celrep.2023.112442

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    sciencedirect.com/science/article/pii/S2211124723004539
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Particulate matter exposure and chronic cerebral hypoperfusion promote oxidative stress and induce neuronal and oligodendrocyte apoptosis in male mice
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      DOI: 10.1002/jnr.25153

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    ncbi.nlm.nih.gov/pmc/articles/PMC10107949/
  53. Mar 2023
  54. europepmc.org europepmc.org
    Pharmacological boosting of cGAS activation sensitizes chemotherapy by enhancing antitumor immunity
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      DOI: 10.1016/j.celrep.2023.112275

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    Secretion of VGF relies on the interplay between LRRK2 and post-Golgi v-SNAREs
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    Choroid plexus-targeted NKCC1 overexpression to treat post-hemorrhagic hydrocephalus
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    TNIP1 inhibits selective autophagy via bipartite interaction with LC3/GABARAP and TAX1BP1
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    Colchicine exerts anti-atherosclerotic and ‑plaque-stabilizing effects targeting foam cell formation
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    The effect of KTKEGV repeat motif and intervening ATVA sequence on α-synuclein solubility and assembly
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    O-fucosylation of thrombospondin type I repeats is dispensable for trafficking thrombospondin 1 to platelet secretory granules
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  61. Feb 2023
  62. www.nature.com www.nature.com
    CTB-targeted protocells enhance ability of lanthionine ketenamine analogs to induce autophagy in motor neuron-like cells
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  63. www.sciencedirect.com www.sciencedirect.com
    Cognitive impairments in a Down syndrome model with abnormal hippocampal and prefrontal dynamics and cytoarchitecture
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  64. Jan 2023
  65. www.cell.com www.cell.com
    Wolbachia RNase HI contributes to virus blocking in the mosquito Aedes aegypti
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  66. Dec 2022
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    Epidermal stratification requires retromer-mediated desmoglein-1 recycling
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  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An ER phospholipid hydrolase drives ER-associated mitochondrial constriction for fission and fusion
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  69. Nov 2022
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    Global profiling of the proteomic changes associated with the post-testicular maturation of mouse spermatozoa
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  71. Oct 2022
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    Smooth muscle Acid-sensing ion channel 1a as a therapeutic target to reverse hypoxic pulmonary hypertension
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    Changes in nuclear pore numbers control nuclear import and stress response of mouse hearts
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  74. Sep 2022
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    Metabolic Profile Variations along the Differentiation of Human-Induced Pluripotent Stem Cells to Dopaminergic Neurons
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  76. Aug 2022
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    The RNA helicase DDX5 cooperates with EHMT2 to sustain alveolar rhabdomyosarcoma growth
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    β-Glucocerebrosidase Deficiency Activates an Aberrant Lysosome-Plasma Membrane Axis Responsible for the Onset of Neurodegeneration
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    Ethanol sustains phosphorylated tau protein in the cultured neonatal rat hippocampus: Implications for fetal alcohol spectrum disorders
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    Developmental cell death of cortical projection neurons is controlled by a Bcl11a/Bcl6‐dependent pathway
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  81. Jul 2022
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    GPCR kinases generate an APH1A phosphorylation barcode to regulate amyloid-β generation
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    The Combination of Δ9-Tetrahydrocannabinol and Cannabidiol Suppresses Mitochondrial Respiration of Human Glioblastoma Cells via Downregulation of Specific Respiratory Chain Proteins
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  84. Jun 2022
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    Bidirectional regulation of synaptic SUMOylation by Group 1 metabotropic glutamate receptors
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    The ER ladder is a unique morphological feature of developing mammalian axons
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  87. May 2022
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    Delta spike P681R mutation enhances SARS-CoV-2 fitness over Alpha variant
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    JAM-A Signals Through the Hippo Pathway to Regulate Intestinal Epithelial Proliferation
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  90. Apr 2022
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    TNFɑ Antagonist in Combination with PD-1 Blocker to Prevent or Retard Malignant Transformation of B[a]P-induced Chronic Lung Inflammation
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    Cytoplasmic PARP1 links the genome instability to the inhibition of antiviral immunity through PARylating cGAS
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  93. Mar 2022
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    C-type natriuretic peptide facilitates autonomic Ca2+ entry in growth plate chondrocytes for stimulating bone growth
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    A genetic compensatory mechanism regulated by Jun and Mef2d modulates the expression of distinct class IIa Hdacs to ensure peripheral nerve myelination and repair
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    Sebocytes contribute to melasma onset
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  97. Jan 2022
  98. www.cell.com www.cell.com
    Pseudouridine synthases modify human pre-mRNA co-transcriptionally and affect pre-mRNA processing
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  99. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Eukaryotic elongation factor 2 kinase regulates foam cell formation via translation of CD36
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    TNFα induces mitochondrial fragmentation and biogenesis in human airway smooth muscle
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  101. Dec 2021
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    CRMP4-mediated fornix development involves Semaphorin-3E signaling pathway
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    The balance of mitochondrial fission and fusion in cortical axons depends on the kinases SadA and SadB
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  104. Nov 2021
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    The multicellular signalling network of ovarian cancer metastases
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  106. Oct 2021
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    Activation of mTORC1 and c-Jun by Prohibitin1 loss in Schwann cells may link mitochondrial dysfunction to demyelination
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  108. Sep 2021
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    Microglia jointly degrade fibrillar alpha-synuclein cargo by distribution through tunneling nanotubes
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    Late adolescence mortality in mice with brain-specific deletion of the volume-regulated anion channel subunit LRRC8A
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  111. Aug 2021
  112. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The role of voltage-gated chloride channels in the epileptogenesis of temporal lobe epilepsy
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    Cav2.1 C‐terminal fragments produced in Xenopus laevis oocytes do not modify the channel expression and functional properties
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    Type I Interferon Receptor Signaling in Astrocytes Regulates Hippocampal Synaptic Plasticity and Cognitive Function of the Healthy CNS
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    MeCP2 Represses the Rate of Transcriptional Initiation of Highly Methylated Long Genes
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    PINK1/Parkin Influences Cell Cycle by Sequestering TBK1 at Damaged Mitochondria, Inhibiting Mitosis
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    A Mechanism for Statin-Induced Susceptibility to Myopathy
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    Mast Cells Induce Blood Brain Barrier Damage in SCD by Causing Endoplasmic Reticulum Stress in the Endothelium
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    PI3K inhibitors protect against glucocorticoid-induced skin atrophy
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    ULK1 and ULK2 Regulate Stress Granule Disassembly Through Phosphorylation and Activation of VCP/p97
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    Microglial Phagocytosis of Newborn Cells Is Induced by Endocannabinoids and Sculpts Sex Differences in Juvenile Rat Social Play
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    Endothelial Calcineurin Signaling Restrains Metastatic Outgrowth by Regulating Bmp2
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    PCNA-Mediated Degradation of p21 Coordinates the DNA Damage Response and Cell Cycle Regulation in Individual Cells
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    Enriched environment enhances β‐adrenergic signaling to prevent microglia inflammation by amyloid‐β
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    A Novel Class of ER Membrane Proteins Regulates ER-Associated Endosome Fission
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    Visual Experience-Dependent Expression of Fn14 Is Required for Retinogeniculate Refinement
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    Simultaneous Ablation of Neuronal Neurofascin and Ankyrin G in Young and Adult Mice Reveals Age-Dependent Increase in Nodal Stability in Myelinated Axons and Differential Effects on the Lifespan
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    DNA Methylation Patterns Separate Senescence from Transformation Potential and Indicate Cancer Risk
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    Genomic Aberrations that Activate D-type Cyclins Are Associated with Enhanced Sensitivity to the CDK4 and CDK6 Inhibitor Abemaciclib
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    SYK Inhibition Induces Apoptosis in Germinal Center-Like B Cells by Modulating the Antiapoptotic Protein Myeloid Cell Leukemia-1, Affecting B-Cell Activation and Antibody Production
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    Nuclear-Import Receptors Reverse Aberrant Phase Transitions of RNA-Binding Proteins with Prion-like Domains
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    GRAM domain proteins specialize functionally distinct ER-PM contact sites in human cells
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    AP-1 Transcription Factors and the BAF Complex Mediate Signal-Dependent Enhancer Selection
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  209. www.sciencedirect.com www.sciencedirect.com
    Lipolysis in Brown Adipocytes Is Not Essential for Cold-Induced Thermogenesis in Mice
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  210. europepmc.org europepmc.org
    Epidermal Growth Factor Receptor neddylation is regulated by a desmosomal-COP9 (Constitutive Photomorphogenesis 9) signalosome complex.
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  211. Nov 2017
  212. rupress.org rupress.org
    New tools for “hot-wiring” clathrin-mediated endocytosis with temporal and spatial precision
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  213. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Mst‐1 deficiency promotes post‐traumatic spinal motor neuron survival via enhancement of autophagy flux
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  214. academic.oup.com academic.oup.com
    The Transcriptome of Estrogen-Independent Mammary Growth in Female Mice Reveals That Not All Mammary Glands Are Created Equally
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    Protein kinase D exerts neuroprotective functions during oxidative stress via Nuclear Factor kappaB‐independent signaling pathways
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    Mechanisms of Paradoxical Activation of AMPK by the Kinase Inhibitors SU6656 and Sorafenib
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    Apoptosis and Compensatory Proliferation Signaling Are Coupled by CrkI-Containing Microvesicles
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  218. bmcbiol.biomedcentral.com bmcbiol.biomedcentral.com
    The Golgi apparatus acts as a platform for TBK1 activation after viral RNA sensing
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    LIX1 regulates YAP1 activity and controls the proliferation and differentiation of stomach mesenchymal progenitors
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