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CD8+MT+ effector T cells from enlarged tumor-draining lymph nodes enhanced anti-tumor immunity and improved prognosis in colorectal cancer

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1. scibot 29 Nov 2025
  
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sciencedirect.com:5037/science/article/pii/S221112472501397X
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Stress-induced sympathetic hyperactivation drives hair follicle necrosis to trigger autoimmunity

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1. scibot 29 Nov 2025
  
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  DOI: 10.1016/j.cell.2025.10.042
  
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sciencedirect.com:5037/science/article/pii/S0092867425012474
Aug 2025
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1-s2.0-S2589004225015962-main-html.html

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1. scibot 12 Aug 2025
  
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Jul 2025
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Human adipose-derived mesenchymal stem cell-derived exosomes induce epithelial remodeling and anti-scar healing revealed by single-cell RNA sequencing

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1. scibot 17 Jul 2025
  
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  DOI: 10.1186/s12951-025-03548-y
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12261776/
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AP-2α/AP-2β transcription factors are key regulators of epidermal homeostasis

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1. scibot 02 Jul 2025
  
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  DOI: 10.1016/j.jid.2023.12.017
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11193656/
Jun 2025
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EGFR controls transcriptional and metabolic rewiring in KRASG12D colorectal cancer

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1. scibot 17 Jun 2025
  
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  DOI: 10.1038/s44321-025-00240-4
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12162862/
May 2025
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Shc1 cooperates with Frs2 and Shp2 to recruit Grb2 in FGF-induced lens development

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1. scibot 21 May 2025
  
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  DOI: 10.7554/eLife.103615
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12055001/
Feb 2025
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Sotorasib resistance triggers epithelial-mesenchymal transition and activates AKT and P38-mediated signaling

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1. scibot 15 Feb 2025
  
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  DOI: 10.3389/fmolb.2025.1537523
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11821485/
Jul 2024
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Spatially distinct epithelial and mesenchymal cell subsets along progressive lineage restriction in the branching embryonic mammary gland

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1. scibot 03 Jul 2024
  
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  DOI: 10.1038/s44318-024-00115-3
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11183262/
May 2024
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Mouse neural tube organoids self-organize floorplate through BMP-mediated cluster competition

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1. scibot 23 May 2024
  
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  DOI: 10.1016/j.devcel.2024.04.021
  
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sciencedirect.com/science/article/pii/S1534580724002971
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Modeling blood-brain barrier formation and cerebral cavernous malformations in human PSC-derived organoids

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1. scibot 16 May 2024
  
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  DOI: 10.1016/j.stem.2024.04.019
  
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SIRT1 mediates the antagonism of Wnt/β-catenin pathway by vitamin D in colon carcinoma cells

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1. scibot 04 May 2024
  
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52.53.155.43/696f49a3546de66e1af8cab87bfc89cda4bd0257/2024.01.21.576539v1.full-html.html
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Combinatorial interpretation of BMP and WNT controls the decision between primitive streak and extraembryonic fates

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1. scibot 01 May 2024
  
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  DOI: 10.1016/j.cels.2024.04.001
  
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sciencedirect.com/science/article/pii/S2405471224001169
Apr 2024
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Oligodendrocyte-derived laminin-γ1 regulates the blood-brain barrier and CNS myelination in mice

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1. scibot 18 Apr 2024
  
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  DOI: 10.1016/j.celrep.2024.114123
  
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sciencedirect.com/science/article/pii/S2211124724004510
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Glutamatergic neuronal activity regulates angiogenesis and blood-retinal barrier maturation via Norrin/β-catenin signaling

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1. scibot 10 Apr 2024
  
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  DOI: 10.1016/j.neuron.2024.03.011
  
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sciencedirect.com/science/article/pii/S089662732400165X
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Class I HDAC inhibitors enhance antitumor efficacy and persistence of CAR-T cells by activation of the Wnt pathway

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1. scibot 05 Apr 2024
  
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  DOI: 10.1016/j.celrep.2024.114065
  
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sciencedirect.com/science/article/pii/S2211124724003930
Feb 2024
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Measurement of adhesion and traction of cells at high yield (MATCHY) reveals an energetic ratchet driving nephron condensation

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1. scibot 15 Feb 2024
  
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  DOI: 10.1101/2024.02.07.579368
  
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biorxiv.org/content/10.1101/2024.02.07.579368v1
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Nephron progenitors rhythmically alternate between renewal and differentiation phases that synchronize with kidney branching morphogenesis

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1. scibot 06 Feb 2024
  
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  DOI: 10.1101/2023.11.21.568157
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10690271/
Jan 2024
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Inosine induces stemness features in CAR-T cells and enhances potency

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1. scibot 26 Jan 2024
  
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  DOI: 10.1016/j.ccell.2024.01.002
  
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sciencedirect.com/science/article/pii/S1535610824000084
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AP-2α/AP-2β transcription factors are key regulators of epidermal homeostasis

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1. scibot 05 Jan 2024
  
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  DOI: 10.1101/2023.12.03.569763
  
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biorxiv.org/content/10.1101/2023.12.03.569763v1
Dec 2023
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A desmosomal cadherin controls multipotent hair follicle stem cell quiescence and orchestrates regeneration through adhesion signaling

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1. scibot 21 Dec 2023
  
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  DOI: 10.1016/j.isci.2023.108568
  
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sciencedirect.com/science/article/pii/S2589004223026457
Nov 2023
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Rho/ROCK activity tunes cell compartment segregation and differentiation in nephron-forming niches

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  DOI: 10.1101/2023.11.08.566308
  
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Integrative multi-omic profiling of adult mouse brain endothelial cells and potential implications in Alzheimer’s disease

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1. scibot 10 Nov 2023
  
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  DOI: 10.1016/j.celrep.2023.113392
  
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sciencedirect.com/science/article/pii/S2211124723014043
Jun 2023
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Altered gut microbiota of obesity subjects promotes colorectal carcinogenesis in mice

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  DOI: 10.1016/j.ebiom.2023.104670
  
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sciencedirect.com/science/article/pii/S2352396423002359
May 2023
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A Wnt-induced lncRNA-DGCR5 splicing switch drives tumor-promoting inflammation in esophageal squamous cell carcinoma

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1. scibot 25 May 2023
  
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  DOI: 10.1016/j.celrep.2023.112542
  
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sciencedirect.com/science/article/pii/S2211124723005533
Mar 2023
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Formation and function of the meningeal arachnoid barrier around the developing mouse brain

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1. scibot 30 Mar 2023
  
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  DOI: 10.1016/j.devcel.2023.03.005
  
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Vascular and perivascular cell profiling reveals the molecular and cellular bases of blood-brain barrier heterogeneity

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1. scibot 23 Mar 2023
  
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  DOI: 10.1101/2021.04.26.441465
  
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biorxiv.org/content/10.1101/2021.04.26.441465v1
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Single-cell transcriptomic profiling redefines the origin and specification of early adrenogonadal progenitors

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  DOI: 10.1016/j.celrep.2023.112191
  
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sciencedirect.com/science/article/pii/S2211124723002024
Oct 2022
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Murine endothelial serine palmitoyltransferase 1 (SPTLC1) is required for vascular development and systemic sphingolipid homeostasis

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1. scibot 26 Oct 2022
  
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  DOI: 10.7554/eLife.78861
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9578713/
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Mural Wnt/β-catenin signaling regulates Lama2 expression to promote neurovascular unit maturation

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1. scibot 25 Oct 2022
  
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  DOI: 10.1242/dev.200610
  
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journals.biologists.com/dev/article/149/17/dev200610/276619/Mural-Wnt-catenin-signaling-regulates-Lama2
Aug 2022
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Internal checkpoint regulates T cell neoantigen reactivity and susceptibility to PD1 blockade

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  DOI: 10.1016/j.medj.2022.07.008
  
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sciencedirect.com/science/article/pii/S266663402200318X
May 2022
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Twist2-driven chromatin remodeling governs the postnatal maturation of dermal fibroblasts

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1. scibot 19 May 2022
  
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  DOI: 10.1016/j.celrep.2022.110821
  
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sciencedirect.com/science/article/pii/S2211124722005927
Mar 2022
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Patterning the embryonic pulmonary mesenchyme

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1. scibot 04 Mar 2022
  
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  DOI: 10.1016/j.isci.2022.103838
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8889149/
Dec 2021
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β-catenin links cell seeding density to global gene expression during mouse embryonic stem cell differentiation

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1. scibot 17 Dec 2021
  
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  DOI: 10.1016/j.isci.2021.103541
  
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Epithelial Wnt secretion drives the progression of inflammation-induced colon carcinoma in murine model

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1. scibot 01 Dec 2021
  
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  DOI: 10.1016/j.isci.2021.103369
  
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Pre-existing chromatin accessibility and gene expression differences among naive CD4+ T cells influence effector potential

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TCF/LEF regulation of the topologically associated domain ADI promotes mESCs to exit the pluripotent ground state

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Spatial transcriptional mapping of the human nephrogenic program

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An in vitro stem cell model of human epiblast and yolk sac interaction

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Temporal Layering of Signaling Effectors Drives Chromatin Remodeling during Hair Follicle Stem Cell Lineage Progression

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Diencephalic Size Is Restricted by a Novel Interplay Between GCN5 Acetyltransferase Activity and Retinoic Acid Signaling

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Dermal EZH2 orchestrates dermal differentiation and epidermal proliferation during murine skin development

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Stk24 protects against obesity-associated metabolic disorders by disrupting the NLRP3 inflammasome

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A calcineurin-mediated scaling mechanism that controls a K+-leak channel to regulate morphogen and growth factor transcription

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Differentiated Daughter Cells Regulate Stem Cell Proliferation and Fate through Intra-tissue Tension

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Distinct Regulatory Programs Control the Latent Regenerative Potential of Dermal Fibroblasts during Wound Healing

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Mechanical instability of adherens junctions overrides intrinsic quiescence of hair follicle stem cells

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A β-catenin-driven switch in TCF/LEF transcription factor binding to DNA target sites promotes commitment of mammalian nephron progenitor cells

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Beta-catenin signaling regulates barrier-specific gene expression in circumventricular organ and ocular vasculatures

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Wnt-Dependent Oligodendroglial-Endothelial Interactions Regulate White Matter Vascularization and Attenuate Injury

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In utero exposure to maternal diabetes impairs nephron progenitor differentiation

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Sphingosine 1-Phosphate Receptor Signaling Establishes AP-1 Gradients to Allow for Retinal Endothelial Cell Specialization

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Lats1/2 Sustain Intestinal Stem Cells and Wnt Activation through TEAD-Dependent and Independent Transcription

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Dysfunction of Hair Follicle Mesenchymal Progenitors Contributes to Age-Associated Hair Loss

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Sphingosine 1-phosphate-regulated transcriptomes in heterogenous arterial and lymphatic endothelium of the aorta

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Neuropsin (OPN5) Mediates Local Light-Dependent Induction of Circadian Clock Genes and Circadian Photoentrainment in Exposed Murine Skin

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Endometrial Axin2+ Cells Drive Epithelial Homeostasis, Regeneration, and Cancer following Oncogenic Transformation

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Impaired Mitochondrial ATP Production Downregulates Wnt Signaling via ER Stress Induction

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Mediator Condensates Localize Signaling Factors to Key Cell Identity Genes

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Untitled document

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Untitled document

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Submucosal Gland Myoepithelial Cells Are Reserve Stem Cells That Can Regenerate Mouse Tracheal Epithelium

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A Glial Signature and Wnt7 Signaling Regulate Glioma-Vascular Interactions and Tumor Microenvironment

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Fibrinogen Activates BMP Signaling in Oligodendrocyte Progenitor Cells and Inhibits Remyelination after Vascular Damage

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Canonical Wnt/β-Catenin Signaling Regulates Postnatal Mouse Epididymal Development But Does Not Affect Epithelial Cell Differentiation

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Differential Wnt signaling activity limits epithelial gland development to the anti-mesometrial side of the mouse uterus - ScienceDirect

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Type XVII collagen coordinates proliferation in the interfollicular epidermis

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Norrin/Frizzled4 signalling in the preneoplastic niche blocks medulloblastoma initiation

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