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    Pan-cancer analysis reveals Rho kinase addiction as a vulnerability of de-differentiated cancer cells
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  3. May 2026
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    Celecoxib potentiates ribociclib-induced apoptosis and anti-tumor activity by co-targeting COX-2/NF-κB and PI3K/AKT/mTOR pathways in hormone receptor-positive/HER2-negative breast cancer
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  5. Feb 2026
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    Raspberry Polyphenols Target Molecular Pathways of Heart Failure
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    Discovery, delineation, and therapeutic targeting of a hyper-translation pathway driving cytokine release syndrome
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    Prolyl endopeptidase is a multifunctional host factor required for FMDV infection
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    The E3 ligase RNF32 controls the IκB kinase complex and NF-κB signaling in intestinal stem cells
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    Protective Effect of Taxifolin Against Monochloroacetic Acid-Induced Skin Damage via Inhibition of the cGAS/STING/NF-κB Pathway
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    The immune response against cancer is modulated by stromal cell fibronectin
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    7,4′-dimethoxy-3-hydroxyflavone, a protease-activated receptor 4 (PAR4) inhibitor with antioxidant activity, ameliorates diabetic endothelial dysfunction
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    Piezo1 senses hyphae and initiates host defense against pathogenic fungi
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    ArfGAP2 promotes STING proton channel activity, cytokine transit, and autoinflammation
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    Cellular deconstruction of the human skeletal muscle microenvironment identifies an exercise-induced histaminergic crosstalk
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  22. Sep 2024
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    Role of SAA1 in Endometrial Extracellular Matrix Remodeling in Polycystic Ovary Syndrome: Implication for Pregnancy Loss
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    IKKɛ induces STING non-IFN immune responses via a mechanism analogous to TBK1
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    Dietary vitamin B3 supplementation induces the antitumor immunity against liver cancer via biased GPR109A signaling in myeloid cell
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    MicroRNA-19b exacerbates systemic sclerosis through promoting Th9 cells
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  28. Jun 2024
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    Metallo-protease Peptidase M84 from Bacillus altitudinis induces ROS-dependent apoptosis in ovarian cancer cells by targeting PAR-1
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  30. Mar 2024
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    Regional modulation of toll-like receptor signaling pathway genes in acute epididymitis in mice
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  32. May 2023
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    YTHDF2 inhibition potentiates radiotherapy antitumor efficacy
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  34. Nov 2022
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    Estrone, the major postmenopausal estrogen, binds ERa to induce SNAI2, epithelial-to-mesenchymal transition, and ER+ breast cancer metastasis
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  36. Sep 2022
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    Na/K-ATPase Suppresses LPS-Induced Pro-Inflammatory Signaling Through Lyn
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  38. Jul 2022
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    LncNSPL facilitates influenza A viral immune escape by restricting TRIM25-mediated K63-linked RIG-I ubiquitination
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  42. Jun 2022
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    Histone H2A ubiquitination resulting from Brap loss of function connects multiple aging hallmarks and accelerates neurodegeneration
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    Phloretin Protects Bovine Rumen Epithelial Cells from LPS-Induced Injury
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    Bladder epithelial cell phosphate transporter inhibition protects mice against uropathogenic Escherichia coli infection
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    Self-developed NF-κB inhibitor 270 protects against LPS-induced acute kidney injury and lung injury through improving inflammation
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  49. Dec 2021
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    Olfactory receptor 5B21 drives breast cancer metastasis
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  51. Oct 2021
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    Differential effects of viral nucleic acid sensor signaling pathways on testicular Sertoli and Leydig cells
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  53. Sep 2021
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    Proteopathic tau primes and activates interleukin-1β via myeloid-cell-specific MyD88- and NLRP3-ASC-inflammasome pathway
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  55. Jul 2021
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    Sustained Secretion of the Antimicrobial Peptide S100A7 Is Dependent on the Downregulation of Caspase-8
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    Palmitate‐induced C/EBP homologous protein activation leads to NF‐κB‐mediated increase in BACE1 activity and amyloid beta genesis
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    Spinal interleukin-1β induces mechanical spinal hyperexcitability in rats: interactions and redundancies with TNF and IL-6
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15438
  60. Jun 2021
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    Canonical NF-κB signaling maintains corneal epithelial integrity and prevents corneal aging via retinoic acid
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    MYC-mediated early glycolysis negatively regulates proinflammatory responses by controlling IRF4 in inflammatory macrophages
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  63. Apr 2021
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    The Major Pre- and Postmenopausal Estrogens Play Opposing Roles in Obesity-Driven Mammary Inflammation and Breast Cancer Development
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  66. Mar 2021
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    Ameliorative activity of aqueous leaf extract from Madhuca longifolia against diclofenac-administered toxicity on rat stomach and intestine
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  68. Oct 2020
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    TDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALS
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  70. Sep 2020
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    NF-κB Dynamics Discriminate between TNF Doses in Single Cells
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    TBK1 and IKKε Act Redundantly to Mediate STING-Induced NF-κB Responses in Myeloid Cells
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    TNFAIP3 Interacting Protein 3 Overexpression Suppresses Nonalcoholic Steatohepatitis by Blocking TAK1 Activation
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  74. Jan 2020
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    Small Heterodimer Partner Controls the Virus-Mediated Antiviral Immune Response by Targeting CREB-Binding Protein in the Nucleus
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  78. Nov 2018
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    Non-canonical NF-κB Antagonizes STING Sensor-Mediated DNA Sensing in Radiotherapy
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    Gain-of-Function Mutation of Card14 Leads to Spontaneous Psoriasis-like Skin Inflammation through Enhanced Keratinocyte Response to IL-17A
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    T Cell Receptor-Regulated TGF-β Type I Receptor Expression Determines T Cell Quiescence and Activation
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    Th9 Cells Represent a Unique Subset of CD4+ T Cells Endowed with the Ability to Eradicate Advanced Tumors
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    Evidence that TLR4 Is Not a Receptor for Saturated Fatty Acids but Mediates Lipid-Induced Inflammation by Reprogramming Macrophage Metabolism
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    Micro Integral Membrane Protein (MIMP), a Newly Discovered Anti-Inflammatory Protein of Lactobacillus Plantarum, Enhances the Gut Barrier and Modulates Microbiota and Inflammatory Cytokines
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  87. jneuroinflammation.biomedcentral.com jneuroinflammation.biomedcentral.com
    Inhibition of HMGB1 reduces rat spinal cord astrocytic swelling and AQP4 expression after oxygen-glucose deprivation and reoxygenation via TLR4 and NF-κB signaling in an IL-6-dependent manner
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  88. Nov 2017
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    Substance P Exacerbates Dopaminergic Neurodegeneration through Neurokinin-1 Receptor-Independent Activation of Microglial NADPH Oxidase
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