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  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Elraglusib Induces Cytotoxicity via Direct Microtubule Destabilization Independently of GSK3 Inhibition
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    1. scibot 21 Dec 2024
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    pmc.ncbi.nlm.nih.gov/articles/PMC11586712/
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Placenta-derived SOD3 deletion impairs maternal behavior via alterations in FGF/FGFR-prolactin signaling axis
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    1. scibot 21 Dec 2024
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  4. Oct 2024
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    Multi-omic human pancreatic islet endoplasmic reticulum and cytokine stress response mapping provides type 2 diabetes genetic insights
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    1. scibot 09 Oct 2024
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    sciencedirect.com/science/article/pii/S155041312400370X
  6. Sep 2024
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    Re-education of Tumor-Associated Macrophages by CXCR2 Blockade Drives Senescence and Tumor Inhibition in Advanced Prostate Cancer
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    1. scibot 25 Sep 2024
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  8. Jul 2024
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mesoporous manganese nanocarrier target delivery metformin for the co-activation STING pathway to overcome immunotherapy resistance
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    1. scibot 26 Jul 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11261061/
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    Comparative transcriptomic profiling reveals a role for Olig1 in promoting axon regeneration
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    1. scibot 17 Jul 2024
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    TSPAN4 influences glioblastoma progression through regulating EGFR stability
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    cell.com/iscience/fulltext/S2589-0042(24)01642-0
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    RNF185 control of COL3A1 expression limits prostate cancer migration and metastatic potential
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    1. scibot 07 Jul 2024
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    Dystrophin 71 deficiency causes impaired aquaporin-4 polarization contributing to glymphatic dysfunction and brain edema in cerebral ischemia
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    sciencedirect.com/science/article/pii/S0969996124001864
  14. Jun 2024
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fully automated viability and toxicity screening—A reliable all‐in‐one attempt
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    1. scibot 25 Jun 2024
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    CRISPR activation screens identify the SWI/SNF ATPases as suppressors of ferroptosis
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    1. scibot 21 Jun 2024
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    RAPSYN-mediated neddylation of BCR-ABL alternatively determines the fate of Philadelphia chromosome-positive leukemia
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    1. scibot 14 Jun 2024
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      DOI: 10.7554/eLife.88375

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  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Anti-tumor effects of tirbanibulin in squamous cell carcinoma cells are mediated via disruption of tubulin-polymerization
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    1. scibot 13 Jun 2024
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  19. May 2024
  20. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 30 May 2024
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16420
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    Protocol for mass spectrometric profiling of lysine malonylation by lysine acetyltransferase in CRISPRi K562 cell lines
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    1. scibot 24 May 2024
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    sciencedirect.com/science/article/pii/S2666166724002399
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    Distinct roles of TREM2 in central nervous system cancers and peripheral cancers
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    sciencedirect.com/science/article/pii/S1535610824001624
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    HuR promotes triglyceride synthesis and intestinal fat absorption
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    sciencedirect.com/science/article/pii/S2211124724005667
  24. Apr 2024
  25. dx.doi.org dx.doi.org
    Zona Glomerulosa–Derived Klotho Modulates Aldosterone Synthase Expression in Young Female Mice
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    Using an ER-specific optogenetic mechanostimulator to understand the mechanosensitivity of the endoplasmic reticulum
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    sciencedirect.com/science/article/pii/S1534580724001801
  27. Feb 2024
  28. www.sciencedirect.com www.sciencedirect.com
    Sialyltransferase ST3GAL4 confers osimertinib resistance and offers strategies to overcome resistance in non-small cell lung cancer
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    1. scibot 29 Feb 2024
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    sciencedirect.com/science/article/pii/S0304383524001551
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    Targeting EMSY-mediated methionine metabolism is a potential therapeutic strategy for triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S2666379124000053
  30. www.nature.com www.nature.com
    A multidimensional atlas of human glioblastoma-like organoids reveals highly coordinated molecular networks and effective drugs
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  31. Jan 2024
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    circGlis3 promotes β-cell dysfunction by inhibiting hnRNPF nuclear translocation and encoding Glis3-348aa protein
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  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    METTL17 is an Fe-S cluster checkpoint for mitochondrial translation
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  34. Dec 2023
  35. www.sciencedirect.com www.sciencedirect.com
    Arp2/3 complex and the pentose phosphate pathway regulate late phases of neutrophil swarming
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    sciencedirect.com/science/article/pii/S2589004223027335
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    ALK inhibitors increase ALK expression and sensitize neuroblastoma cells to ALK.CAR-T cells
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    sciencedirect.com/science/article/pii/S1535610823003951
  37. Nov 2023
  38. 52.53.155.43 52.53.155.43
    mvad090-html.html
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  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Extra-cardiac BCAA catabolism lowers blood pressure and protects from heart failure
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    ncbi.nlm.nih.gov/pmc/articles/PMC9633425/
  40. Jun 2023
  41. www.sciencedirect.com www.sciencedirect.com
    PLIN5 interacts with FATP4 at membrane contact sites to promote lipid droplet-to-mitochondria fatty acid transport
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    sciencedirect.com/science/article/pii/S1534580723002393
  42. May 2023
  43. www.sciencedirect.com www.sciencedirect.com
    Loss of AMPKα2 promotes melanoma tumor growth and brain metastasis
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    sciencedirect.com/science/article/pii/S2589004223008684
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    Tyrosine kinases compete for growth hormone receptor binding and regulate receptor mobility and degradation
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    sciencedirect.com/science/article/pii/S2211124723005016
  45. www.science.org www.science.org
    Macrophage ACE2 is necessary for SARS-CoV-2 replication and subsequent cytokine responses that restrict continued virion release
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      DOI: 10.1126/scisignal.abq1366

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    science.org/doi/10.1126/scisignal.abq1366
  46. Apr 2023
  47. www.sciencedirect.com www.sciencedirect.com
    Metformin triggers a kidney GDF15-dependent area postrema axis to regulate food intake and body weight
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    sciencedirect.com/science/article/pii/S155041312300092X
  48. Mar 2023
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Histone malonylation is regulated by SIRT5 and KAT2A
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    ncbi.nlm.nih.gov/pmc/articles/PMC9985052/
  50. Feb 2023
  51. www.sciencedirect.com www.sciencedirect.com
    Transcriptome, proteome, and protein synthesis within the intracellular cytomatrix
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    sciencedirect.com/science/article/pii/S2589004223000421
  52. www.biorxiv.org www.biorxiv.org
    A multidimensional atlas of human glioblastoma organoids reveals highly coordinated molecular networks and effective drugs
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    biorxiv.org/content/10.1101/2023.01.24.525374v1
  53. Jan 2023
  54. www.sciencedirect.com www.sciencedirect.com
    Opioid-induced fragile-like regulatory T cells contribute to withdrawal
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    sciencedirect.com/science/article/pii/S0092867422015732
  55. Dec 2022
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    ΔNp63/p73 drive metastatic colonization by controlling a regenerative epithelial stem cell program in quasi-mesenchymal cancer stem cells
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    Opa1 and Drp1 reciprocally regulate cristae morphology, ETC function, and NAD+ regeneration in KRas-mutant lung adenocarcinoma
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  60. Nov 2022
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  62. Oct 2022
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  64. Jul 2022
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    Efficacy of Combined Use of Everolimus and Second-Generation Pan-EGRF Inhibitors in KRAS Mutant Non-Small Cell Lung Cancer Cell Lines
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    Evidence for reduced BRCA2 functional activity in Homo sapiens after divergence from the chimpanzee-human last common ancestor
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    Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair
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    Astrocytic Hydrogen Sulfide Regulates Supraoptic Cellular Activity in the Adaptive Response of Lactating Rats to Chronic Social Stress - Dongyang Li, Haitao Liu, Hongyang Wang, Shuwei Jia, Xiaoran Wang, Shuo Ling, Guichuan Chen, Xiaoyu Liu, Yu-Feng Wang, 2021
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    Characterising proteolysis during SARS-CoV-2 infection identifies viral cleavage sites and cellular targets with therapeutic potential
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    Decreased Expression of the Host Long-Noncoding RNA-GM Facilitates Viral Escape by Inhibiting the Kinase activity TBK1 via S-glutathionylation
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    The Major Pre- and Postmenopausal Estrogens Play Opposing Roles in Obesity-Driven Mammary Inflammation and Breast Cancer Development
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  113. Feb 2021
  114. www.nature.com www.nature.com
    MBNL1 regulates essential alternative RNA splicing patterns in MLL-rearranged leukemia
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  115. Sep 2020
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    The testis protein ZNF165 is a SMAD3 cofactor that coordinates oncogenic TGFβ signaling in triple-negative breast cancer
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  117. www.sciencedirect.com www.sciencedirect.com
    Glucose Response by Stem Cell-Derived β Cells In Vitro Is Inhibited by a Bottleneck in Glycolysis
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  118. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  119. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Melanoblast transcriptome analysis reveals pathways promoting melanoma metastasis
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  120. www.sciencedirect.com www.sciencedirect.com
    Symmetric Arginine Dimethylation Is Selectively Required for mRNA Splicing and the Initiation of Type I and Type III Interferon Signaling
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    Systematic Characterization of Recurrent Genomic Alterations in Cyclin-Dependent Kinases Reveals Potential Therapeutic Strategies for Cancer Treatment
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    Endocrine-Exocrine Signaling Drives Obesity-Associated Pancreatic Ductal Adenocarcinoma
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  125. Jan 2020
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    The RNA Helicase DDX6 Controls Cellular Plasticity by Modulating P-Body Homeostasis
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    A Genome-wide Functional Signature Ontology Map and Applications to Natural Product Mechanism of Action Discovery
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    Comprehensive Proteomics Analysis of Stressed Human Islets Identifies GDF15 as a Target for Type 1 Diabetes Intervention
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      DOI: 10.1016/j.cmet.2019.12.005

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    Transient Receptor Potential V Channels Are Essential for Glucose Sensing by Aldolase and AMPK
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      DOI: 10.1016/j.cmet.2019.05.018

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    Torin2 Exploits Replication and Checkpoint Vulnerabilities to Cause Death of PI3K-Activated Triple-Negative Breast Cancer Cells
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  131. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Drp1 Promotes KRas-Driven Metabolic Changes to Drive Pancreatic Tumor Growth
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    Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair
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      DOI: 10.1016/j.ccell.2019.01.020

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  133. www.sciencedirect.com www.sciencedirect.com
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      DOI: 10.1016/j.celrep.2019.04.041

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  134. Nov 2018
  135. www.sciencedirect.com www.sciencedirect.com
    COMMD5/HCaRG Hooks Endosomes on Cytoskeleton and Coordinates EGFR Trafficking
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  136. europepmc.org europepmc.org
    Pan-RAF and MEK vertical inhibition enhances therapeutic response in non-V600 BRAF mutant cells
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  137. www.sciencedirect.com www.sciencedirect.com
    SOD1 Phosphorylation by mTORC1 Couples Nutrient Sensing and Redox Regulation
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    sciencedirect.com/science/article/pii/S1097276518302326
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    AIDA Selectively Mediates Downregulation of Fat Synthesis Enzymes by ERAD to Retard Intestinal Fat Absorption and Prevent Obesity
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    Chemistry-First Approach for Nomination of Personalized Treatment in Lung Cancer
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  140. Nov 2017
  141. www.sciencedirect.com www.sciencedirect.com
    Tumor Evolution of Glioma-Intrinsic Gene Expression Subtypes Associates with Immunological Changes in the Microenvironment
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