96 Matching Annotations
  1. Jun 2024
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fully automated viability and toxicity screening—A reliable all‐in‐one attempt
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    1. scibot 25 Jun 2024
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      DOI: 10.1002/cam4.7392

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    ncbi.nlm.nih.gov/pmc/articles/PMC11193055/
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    CRISPR activation screens identify the SWI/SNF ATPases as suppressors of ferroptosis
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    1. scibot 21 Jun 2024
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    sciencedirect.com/science/article/pii/S2211124724006739
  4. elifesciences.org elifesciences.org
    RAPSYN-mediated neddylation of BCR-ABL alternatively determines the fate of Philadelphia chromosome-positive leukemia
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    1. scibot 14 Jun 2024
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      DOI: 10.7554/eLife.88375

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    Anti-tumor effects of tirbanibulin in squamous cell carcinoma cells are mediated via disruption of tubulin-polymerization
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    1. scibot 13 Jun 2024
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  6. May 2024
  7. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 30 May 2024
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      DOI: 10.1111/bph.16420

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16420
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    Protocol for mass spectrometric profiling of lysine malonylation by lysine acetyltransferase in CRISPRi K562 cell lines
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    sciencedirect.com/science/article/pii/S2666166724002399
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    Distinct roles of TREM2 in central nervous system cancers and peripheral cancers
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    1. scibot 24 May 2024
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    sciencedirect.com/science/article/pii/S1535610824001624
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    HuR promotes triglyceride synthesis and intestinal fat absorption
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    1. scibot 16 May 2024
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  11. Apr 2024
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    Zona Glomerulosa–Derived Klotho Modulates Aldosterone Synthase Expression in Young Female Mice
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    Using an ER-specific optogenetic mechanostimulator to understand the mechanosensitivity of the endoplasmic reticulum
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  14. Feb 2024
  15. www.sciencedirect.com www.sciencedirect.com
    Sialyltransferase ST3GAL4 confers osimertinib resistance and offers strategies to overcome resistance in non-small cell lung cancer
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    1. scibot 29 Feb 2024
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    sciencedirect.com/science/article/pii/S0304383524001551
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    Targeting EMSY-mediated methionine metabolism is a potential therapeutic strategy for triple-negative breast cancer
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  17. link.springer.com link.springer.com
    A multidimensional atlas of human glioblastoma-like organoids reveals highly coordinated molecular networks and effective drugs
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    1. scibot 01 Feb 2024
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      DOI: 10.1038/s41698-024-00500-5

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  18. Jan 2024
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    circGlis3 promotes β-cell dysfunction by inhibiting hnRNPF nuclear translocation and encoding Glis3-348aa protein
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    1. scibot 18 Jan 2024
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      DOI: 10.1016/j.isci.2023.108680

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  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    METTL17 is an Fe-S cluster checkpoint for mitochondrial translation
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    1. scibot 11 Jan 2024
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  21. Dec 2023
  22. www.sciencedirect.com www.sciencedirect.com
    Arp2/3 complex and the pentose phosphate pathway regulate late phases of neutrophil swarming
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    sciencedirect.com/science/article/pii/S2589004223027335
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    ALK inhibitors increase ALK expression and sensitize neuroblastoma cells to ALK.CAR-T cells
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    sciencedirect.com/science/article/pii/S1535610823003951
  24. Nov 2023
  25. 52.53.155.43 52.53.155.43
    mvad090-html.html
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  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Extra-cardiac BCAA catabolism lowers blood pressure and protects from heart failure
    1
    1. scibot 04 Nov 2023
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      DOI: 10.1016/j.cmet.2022.09.008

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    ncbi.nlm.nih.gov/pmc/articles/PMC9633425/
  27. Jun 2023
  28. www.sciencedirect.com www.sciencedirect.com
    PLIN5 interacts with FATP4 at membrane contact sites to promote lipid droplet-to-mitochondria fatty acid transport
    1
    1. scibot 08 Jun 2023
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    sciencedirect.com/science/article/pii/S1534580723002393
  29. May 2023
  30. www.sciencedirect.com www.sciencedirect.com
    Loss of AMPKα2 promotes melanoma tumor growth and brain metastasis
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    sciencedirect.com/science/article/pii/S2589004223008684
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    Tyrosine kinases compete for growth hormone receptor binding and regulate receptor mobility and degradation
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      DOI: 10.1016/j.celrep.2023.112490

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  32. www.science.org www.science.org
    Macrophage ACE2 is necessary for SARS-CoV-2 replication and subsequent cytokine responses that restrict continued virion release
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      DOI: 10.1126/scisignal.abq1366

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  33. Apr 2023
  34. www.sciencedirect.com www.sciencedirect.com
    Metformin triggers a kidney GDF15-dependent area postrema axis to regulate food intake and body weight
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    sciencedirect.com/science/article/pii/S155041312300092X
  35. Mar 2023
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Histone malonylation is regulated by SIRT5 and KAT2A
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      DOI: 10.1016/j.isci.2023.106193

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    ncbi.nlm.nih.gov/pmc/articles/PMC9985052/
  37. Feb 2023
  38. www.sciencedirect.com www.sciencedirect.com
    Transcriptome, proteome, and protein synthesis within the intracellular cytomatrix
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  39. www.biorxiv.org www.biorxiv.org
    A multidimensional atlas of human glioblastoma organoids reveals highly coordinated molecular networks and effective drugs
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    biorxiv.org/content/10.1101/2023.01.24.525374v1
  40. Jan 2023
  41. www.sciencedirect.com www.sciencedirect.com
    Opioid-induced fragile-like regulatory T cells contribute to withdrawal
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  42. Dec 2022
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    ΔNp63/p73 drive metastatic colonization by controlling a regenerative epithelial stem cell program in quasi-mesenchymal cancer stem cells
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  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Opa1 and Drp1 reciprocally regulate cristae morphology, ETC function, and NAD+ regeneration in KRas-mutant lung adenocarcinoma
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    Hypoxic activation of PFKFB4 in breast tumor microenvironment shapes metabolic and cellular plasticity to accentuate metastatic competence
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    sciencedirect.com/science/article/pii/S2211124722016394
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The κ-opioid receptor-induced autophagy is implicated in stress-driven synaptic alterations
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    ncbi.nlm.nih.gov/pmc/articles/PMC9709411/
  47. Nov 2022
  48. www.cell.com www.cell.com
    Downregulation of hepatic ceruloplasmin ameliorates NAFLD via SCO1-AMPK-LKB1 complex
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    cell.com/cell-reports/abstract/S2211-1247(22)01348-1
  49. Oct 2022
  50. www.sciencedirect.com www.sciencedirect.com
    Isoform-specific inhibition of FGFR signaling achieved by a de-novo-designed mini-protein
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    sciencedirect.com/science/article/pii/S2211124722014012
  51. Jul 2022
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Efficacy of Combined Use of Everolimus and Second-Generation Pan-EGRF Inhibitors in KRAS Mutant Non-Small Cell Lung Cancer Cell Lines
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      DOI: 10.3390/ijms23147774

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    ncbi.nlm.nih.gov/pmc/articles/PMC9317664/
  53. Jun 2022
  54. www.sciencedirect.com www.sciencedirect.com
    M2 macrophage-derived exosomal microRNA-411-5p impedes the activation of hepatic stellate cells by targeting CAMSAP1 in NASH model
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    sciencedirect.com/science/article/pii/S2589004222008690
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    A pro-metastatic tRNA fragment drives Nucleolin oligomerization and stabilization of its bound metabolic mRNAs
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    sciencedirect.com/science/article/pii/S1097276522004427
  56. May 2022
  57. www.sciencedirect.com www.sciencedirect.com
    Evidence for reduced BRCA2 functional activity in Homo sapiens after divergence from the chimpanzee-human last common ancestor
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  112. Jan 2020
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    The RNA Helicase DDX6 Controls Cellular Plasticity by Modulating P-Body Homeostasis
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    A Genome-wide Functional Signature Ontology Map and Applications to Natural Product Mechanism of Action Discovery
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      DOI: 10.1016/j.chembiol.2019.07.008

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    Comprehensive Proteomics Analysis of Stressed Human Islets Identifies GDF15 as a Target for Type 1 Diabetes Intervention
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      DOI: 10.1016/j.cmet.2019.12.005

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    Transient Receptor Potential V Channels Are Essential for Glucose Sensing by Aldolase and AMPK
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      DOI: 10.1016/j.cmet.2019.05.018

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    Torin2 Exploits Replication and Checkpoint Vulnerabilities to Cause Death of PI3K-Activated Triple-Negative Breast Cancer Cells
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    Drp1 Promotes KRas-Driven Metabolic Changes to Drive Pancreatic Tumor Growth
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    Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair
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      DOI: 10.1016/j.ccell.2019.01.020

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  121. Nov 2018
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    COMMD5/HCaRG Hooks Endosomes on Cytoskeleton and Coordinates EGFR Trafficking
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  123. europepmc.org europepmc.org
    Pan-RAF and MEK vertical inhibition enhances therapeutic response in non-V600 BRAF mutant cells
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    SOD1 Phosphorylation by mTORC1 Couples Nutrient Sensing and Redox Regulation
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    AIDA Selectively Mediates Downregulation of Fat Synthesis Enzymes by ERAD to Retard Intestinal Fat Absorption and Prevent Obesity
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    Chemistry-First Approach for Nomination of Personalized Treatment in Lung Cancer
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  127. Nov 2017
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    Tumor Evolution of Glioma-Intrinsic Gene Expression Subtypes Associates with Immunological Changes in the Microenvironment
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      Curator: @chewbeccax

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