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Bap1-mediated deubiquitination determines immune tolerance and anti-tumor immunity via modulating eTreg cell differentiation and ferroptosis

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  DOI: 10.1038/s41418-026-01846-y
  
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nature.com/articles/s41418-026-01846-y
Aug 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Cblb Gene Editing in T Cells Sustains Expansion and Immunogenic CAR T Tumor Killing Under Chronic Antigenic Stimulation

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  DOI: 10.3390/cells15151407
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13464884/
Jul 2026
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A poly(I:C)/QS-21-based in situ vaccine synergizes with anti-PD-1 therapy to overcome tumor immunoresistance

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  DOI: 10.1016/j.xcrm.2026.102932
  
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sciencedirect.com/science/article/pii/S2666379126003496
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LEF1 and niche factors determine T cell stemness across chronic diseases

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  DOI: 10.1016/j.cell.2026.06.022
  
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sciencedirect.com/science/article/pii/S0092867426007099
Feb 2026
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Law-NQO1 redox boosts the pentose phosphate pathway to confer stem-like properties and antitumor durability in effector CD8+ T cells

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1. scibot 26 Feb 2026
  
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  DOI: 10.1016/j.chembiol.2026.02.001
  
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sciencedirect.com/science/article/pii/S2451945626000334
Dec 2025
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Metformin hijacks AMPK-ERK1/2 signaling to trigger a pathogenic “selection trap” and thymic atrophy

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1. scibot 25 Dec 2025
  
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  DOI: 10.1016/j.celrep.2025.116762
  
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sciencedirect.com/science/article/pii/S2211124725015347
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2025.12.04.692214v1.full-html.html

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  DOI: 10.64898/2025.12.04.692214
  
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54.241.53.176/5fc200e8d22c6941d9a65233a02e8f8a1a806803/2025.12.04.692214v1.full-html.html
Nov 2025
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Vitamin B6 preserves the stemness-like phenotypes and antitumor ability of CD8+ T cells

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  DOI: 10.1016/j.devcel.2025.10.017
  
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sciencedirect.com:5037/science/article/pii/S1534580725006914
Aug 2025
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A RAS(ON) Multi-Selective Inhibitor Combination Therapy Triggers Long-term Tumor Control through Senescence-Associated Tumor-Immune Equilibrium in Pancreatic Ductal Adenocarcinoma

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  DOI: 10.1158/2159-8290.CD-24-1425
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12319406/
Jul 2025
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Structure of gut microbial glycolipid modulates host inflammatory response

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  DOI: 10.1016/j.cell.2025.05.016
  
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sciencedirect.com/science/article/pii/S0092867425005665
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Augment proteasome inhibitor efficacy activates CD8+ T cell-mediated antitumor immunity in breast cancer

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  DOI: 10.1016/j.xcrm.2025.102211
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12281435/
May 2025
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RAG suppresses group 2 innate lymphoid cells

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1. scibot 22 May 2025
  
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  DOI: 10.7554/eLife.98287
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12055012/
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Dietary lipid overload creates a suppressive environment that impedes the antiviral functions of NK cells

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1. scibot 18 May 2025
  
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  DOI: 10.1016/j.isci.2025.112396
  
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sciencedirect.com/science/article/pii/S2589004225006571
Dec 2024
www.cell.com www.cell.com

Mechanism of enhancing chemotherapy efficacy in pancreatic ductal adenocarcinoma with paricalcitol and hydroxychloroquine

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  DOI: 10.1016/j.xcrm.2024.101881
  
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cell.com/cell-reports-medicine/fulltext/S2666-3791(24)00652-9
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Interleukin-2 receptor signaling acts as a checkpoint that influences the distribution of regulatory T cell subsets

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1. scibot 18 Dec 2024
  
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  DOI: 10.1016/j.isci.2024.111248
  
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sciencedirect.com/science/article/pii/S2589004224024738
Aug 2024
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The acetyltransferase KAT7 is required for thymic epithelial cell expansion, expression of AIRE target genes, and thymic tolerance

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1. scibot 02 Aug 2024
  
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  DOI: 10.1126/sciimmunol.abb6032
  
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science.org/doi/10.1126/sciimmunol.abb6032
Jul 2024
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Metabolic reprogramming and dysregulated IL-17 production impairs CD4 T cell function post sepsis

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1. scibot 19 Jul 2024
  
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  DOI: 10.1016/j.isci.2024.110114
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11251092/
May 2024
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The CD8+ T cell tolerance checkpoint triggers a distinct differentiation state defined by protein translation defects

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1. scibot 23 May 2024
  
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  DOI: 10.1016/j.immuni.2024.04.026
  
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cell.com/immunity/fulltext/S1074-7613(24)00231-0
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Decreased GATA3 levels cause changed mouse cutaneous innate lymphoid cell fate, facilitating hair follicle recycling

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  DOI: 10.1016/j.devcel.2024.04.015
  
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sciencedirect.com/science/article/pii/S1534580724002685
Jun 2023
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Platelets and mast cells promote pathogenic eosinophil recruitment during invasive fungal infection via the 5-HIAA-GPR35 ligand-receptor system

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  DOI: 10.1016/j.immuni.2023.05.006
  
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sciencedirect.com/science/article/pii/S1074761323002236
Apr 2023
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Early immune pressure initiated by tissue-resident memory T cells sculpts tumor evolution in non-small cell lung cancer

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  DOI: 10.1016/j.ccell.2023.03.019
  
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sciencedirect.com/science/article/pii/S1535610823000922
Aug 2022
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Lymphatic migration of unconventional T cells promotes site-specific immunity in distinct lymph nodes

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  DOI: 10.1016/j.immuni.2022.07.019
  
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sciencedirect.com/science/article/pii/S1074761322003545
Feb 2022
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Neutrophil extracellular traps and their histones promote Th17 cell differentiation directly via TLR2

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  DOI: 10.1038/s41467-022-28172-4
  
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nature.com/articles/s41467-022-28172-4
Sep 2021
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Cognate recognition of microbial antigens defines constricted CD4+ T cell receptor repertoires in the inflamed colon

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1. scibot 28 Sep 2021
  
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  DOI: 10.1016/j.immuni.2021.08.014
  
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sciencedirect.com/science/article/pii/S1074761321003460
Aug 2021
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Intercellular cGAMP transmission induces innate immune activation and tissue inflammation in Trex1 deficiency

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  DOI: 10.1016/j.isci.2021.102833
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8326191/
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Untitled document

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  DOI: 10.1016/j.immuni.2018.10.007
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6303219/
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Untitled document

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  DOI: 10.1016/j.immuni.2018.10.007
  
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sciencedirect.com/science/article/pii/S1074761318304485
May 2021
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Resident memory T cells in tumor-distant tissues fortify against metastasis formation

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  DOI: 10.1016/j.celrep.2021.109118
  
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sciencedirect.com/science/article/pii/S2211124721004575
Apr 2021
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Gut microbial metabolites facilitate anticancer therapy efficacy by modulating cytotoxic CD8+ T cell immunity

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  DOI: 10.1016/j.cmet.2021.03.002
  
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Single-cell chromatin accessibility landscape identifies tissue repair program in human regulatory T cells

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sciencedirect.com/science/article/pii/S1074761321001199
Nov 2018
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Untitled document

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sciencedirect.com/science/article/pii/S1074761318303881
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

KLRG1+ Effector CD8+ T Cells Lose KLRG1, Differentiate into All Memory T Cell Lineages, and Convey Enhanced Protective Immunity

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1. scibot 05 Nov 2018
  
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pmc.ncbi.nlm.nih.gov/articles/PMC6465538/