40 Matching Annotations
  1. Last 7 days
  2. www.sciencedirect.com www.sciencedirect.com
    Pharmacologically targeting CDK12 induces BRCAness and synergizes with merestinib to exacerbate DNA damage in high-risk neuroblastoma
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    sciencedirect.com/science/article/pii/S2211124726010752
  3. Oct 2026
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    MIR17HG Expression Is Transcriptionally Regulated by PAX3::FOXO1 and MYCN and is Necessary for Oncogenic Activity in Fusion-Positive Rhabdomyosarcoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC13641197/
  5. Sep 2026
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PLK1 inhibition by volasertib suppresses key transcriptional regulators underlying fibroblast activation and pulmonary fibrosis
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    pmc.ncbi.nlm.nih.gov/articles/PMC13531454/
  7. Aug 2026
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    AURORA A interacts with DICER and SETD2 to promote S-phase progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC13458143/
  9. Apr 2026
  10. aacrjournals.org aacrjournals.org
    Extrachromosomal DNA-Driven Oncogene Dosage Heterogeneity Promotes Rapid Adaptation to Therapy in MYCN-Amplified Cancers
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    aacrjournals.org/cancerdiscovery/article/15/10/2054/765955/Extrachromosomal-DNA-Driven-Oncogene-Dosage
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Inhibition of USP7 destabilizes the noncanonical PRC1.1 complex and induces neuroblastoma differentiation
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    pmc.ncbi.nlm.nih.gov/articles/PMC13082235/
  12. Feb 2026
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CDK2 inhibition promotes neuronal differentiation in neuroblastoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12881557/
  14. May 2025
  15. www.sciencedirect.com www.sciencedirect.com
    Single-cell MultiOmics and spatial transcriptomics demonstrate neuroblastoma developmental plasticity
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    sciencedirect.com/science/article/pii/S1534580725002515
  16. Jan 2025
  17. www.sciencedirect.com www.sciencedirect.com
    Targeting N-Myc in neuroblastoma with selective Aurora kinase A degraders
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    sciencedirect.com/science/article/pii/S2451945624005166
  18. Dec 2024
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    MYC Drives mRNA Pseudouridylation to Mitigate Proliferation-Induced Cellular Stress during Cancer Development
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    pmc.ncbi.nlm.nih.gov/articles/PMC11609627/
  20. Aug 2024
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Association with TFIIIC limits MYCN localisation in hubs of active promoters and chromatin accumulation of non-phosphorylated RNA polymerase II
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    ncbi.nlm.nih.gov/pmc/articles/PMC11343564/
  22. Jul 2024
  23. 52.53.155.43 52.53.155.43
    1-s2.0-S1535610824002319-mmc1-html.html
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    52.53.155.43/fa631816ea536ebd5d77bd5edcecb27537053850/1-s2.0-S1535610824002319-mmc1-html.html
  24. www.sciencedirect.com www.sciencedirect.com
    Targeting the mSWI/SNF complex in POU2F-POU2AF transcription factor-driven malignancies
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    sciencedirect.com/science/article/pii/S1535610824002319
  25. Jun 2024
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The TERT Promoter is Polycomb-Repressed in Neuroblastoma Cells with Long Telomeres
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    ncbi.nlm.nih.gov/pmc/articles/PMC11188873/
  27. May 2024
  28. www.sciencedirect.com www.sciencedirect.com
    The MYCN oncoprotein is an RNA-binding accessory factor of the nuclear exosome targeting complex
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    sciencedirect.com/science/article/pii/S1097276524002855
  29. Mar 2024
  30. www.sciencedirect.com www.sciencedirect.com
    Histone lysine demethylase 4 family proteins maintain the transcriptional program and adrenergic cellular state of MYCN-amplified neuroblastoma
    2
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    sciencedirect.com/science/article/pii/S2666379124001149
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metabolic reprogramming of cancer cells by JMJD6-mediated pre-mRNA splicing associated with therapeutic response to splicing inhibitor
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    ncbi.nlm.nih.gov/pmc/articles/PMC10942784/
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ALK upregulates POSTN and WNT signaling to drive neuroblastoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11101011/
  33. Feb 2024
  34. www.sciencedirect.com www.sciencedirect.com
    Direct reprogramming of non-limb fibroblasts to cells with properties of limb progenitors
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    sciencedirect.com/science/article/pii/S1534580723006901
  35. Jul 2023
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Caffeine supplementation and FOXM1 inhibition enhance the antitumor effect of statins in neuroblastoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10320471/
  37. Jun 2023
  38. 52.53.155.43 52.53.155.43
    can-22-3450-html.html
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    52.53.155.43/d74c78a2e62f04f8ffa00018470c131fb0d65945/can-22-3450-html.html
  39. Feb 2023
  40. aacrjournals.org aacrjournals.org
    Mitochondrial uncoupling induces epigenome remodeling and promotes differentiation in neuroblastoma
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    aacrjournals.org/cancerres/article/83/2/181/715072/Mitochondrial-Uncoupling-Induces-Epigenome
  41. Aug 2022
  42. www.sciencedirect.com www.sciencedirect.com
    Targeting HOTAIRM1 ameliorates glioblastoma by disrupting mitochondrial oxidative phosphorylation and serine metabolism
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    sciencedirect.com/science/article/pii/S2589004222010951
  43. Jun 2022
  44. www.nature.com www.nature.com
    MYCN-driven fatty acid uptake is a metabolic vulnerability in neuroblastoma
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    nature.com/articles/s41467-022-31331-2
  45. Dec 2021
  46. www.nature.com www.nature.com
    KDM6B promotes activation of the oncogenic CDK4/6-pRB-E2F pathway by maintaining enhancer activity in MYCN-amplified neuroblastoma
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    nature.com/articles/s41467-021-27502-2
  47. www.cell.com www.cell.com
    MYC assembles and stimulates topoisomerases 1 and 2 in a “topoisome”
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    cell.com/molecular-cell/fulltext/S1097-2765(21)00996-5
  48. Nov 2021
  49. www.cell.com www.cell.com
    MYCN recruits the nuclear exosome complex to RNA polymerase II to prevent transcription-replication conflicts
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    cell.com/molecular-cell/fulltext/S1097-2765(21)00952-7
  50. Jul 2021
  51. www.sciencedirect.com www.sciencedirect.com
    Binary pan-cancer classes with distinct vulnerabilities defined by pro- or anti-cancer YAP/TEAD activity
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    sciencedirect.com/science/article/pii/S153561082100338X
  52. Apr 2021
  53. www.sciencedirect.com www.sciencedirect.com
    Integrated Metabolic and Epigenomic Reprograming by H3K27M Mutations in Diffuse Intrinsic Pontine Gliomas
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    sciencedirect.com/science/article/pii/S153561082030369X
  54. Sep 2020
  55. elifesciences.org elifesciences.org
    Hidden long-range memories of growth and cycle speed correlate cell cycles in lineage trees
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    elifesciences.org/articles/51002
  56. cancerres.aacrjournals.org cancerres.aacrjournals.org
    Suppression of ABCE1-mediated mRNA translation limits N-MYC-driven cancer progression
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    cancerres.aacrjournals.org/content/80/17/3706
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Increased Efficacy of Histone Methyltransferase G9a Inhibitors Against MYCN-Amplified Neuroblastoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC7269128/
  58. Aug 2020
  59. elifesciences.org elifesciences.org
    Hidden long-range memories of growth and cycle speed correlate cell cycles in lineage trees
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    elifesciences.org/articles/51002
  60. Jan 2020
  61. www.sciencedirect.com www.sciencedirect.com
    Engineering Genetic Predisposition in Human Neuroepithelial Stem Cells Recapitulates Medulloblastoma Tumorigenesis
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    sciencedirect.com/science/article/pii/S1934590919302176
  62. Nov 2017
  63. www.sciencedirect.com www.sciencedirect.com
    MYC Controls Human Pluripotent Stem Cell Fate Decisions through Regulation of Metabolic Flux
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    sciencedirect.com/science/article/pii/S1934590917303363
  64. www.sciencedirect.com www.sciencedirect.com
    Identification of GPC2 as an Oncoprotein and Candidate Immunotherapeutic Target in High-Risk Neuroblastoma
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    sciencedirect.com/science/article/pii/S153561081730346X
  65. www.sciencedirect.com www.sciencedirect.com
    Cell-Cycle Position of Single MYC-Driven Cancer Cells Dictates Their Susceptibility to a Chemotherapeutic Drug
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    sciencedirect.com/science/article/pii/S2405471217303319