173 Matching Annotations
  1. Last 7 days
  2. www.sciencedirect.com www.sciencedirect.com
    Impaired brain-gut circuit for gut motility dysfunction in mouse models of Parkinson’s disease
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124726009551
  3. Aug 2026
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Soluble α-synuclein oligomers drive transient corticostriatal pathology and delayed nigral vulnerability in a mouse model of early α-synucleinopathy
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC13479984/
  5. www.sciencedirect.com www.sciencedirect.com
    Cholesterol enhances lysosome-autophagosome fusion for better α-synuclein clearance in GBA L444P-mutated Parkinson disease
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124726008788
  6. Jun 2026
  7. www.sciencedirect.com www.sciencedirect.com
    Genetic suppressions of CRMP2 phosphorylation ameliorate α-synuclein accumulation in an □-synucleinopathy mouse model
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S0304394026001618
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Knockout of the LRRK2-counteracting RAB phosphatase PPM1H disrupts axonal autophagy and exacerbates alpha-synuclein aggregation
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC13196427/
  9. May 2026
  10. www.sciencedirect.com www.sciencedirect.com
    Secreted GPNMB enhances uptake of fibrillar alpha-synuclein in a non-cell-autonomous process that can be blocked by anti-GPNMB antibodies
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S0896627326003284
  11. Apr 2026
  12. www.sciencedirect.com www.sciencedirect.com
    Peptide-Mediated Delivery of α-Synuclein Targeting ASO: Pharmacokinetics, Safety, and CNS Efficacy in a Synucleinopathy Model
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S0090955626000735
  13. www.biorxiv.org www.biorxiv.org
    Rise-and-fall dynamics reveal a molecular and cellular vulnerability axis in prion-like α-synuclein propagation
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    biorxiv.org/content/10.64898/2026.03.27.714785v1
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Faecalibacterium prausnitzii, depleted in the Parkinson’s disease microbiome, improves motor deficits in α-synuclein overexpressing mice
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC13077053/
  15. www.sciencedirect.com www.sciencedirect.com
    Protocol to study synapse density or volume—SynDOVE—in brain using confocal microscopy and Imaris three-dimensional surface rendering software
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2666166726001188
  16. Mar 2026
  17. www.sciencedirect.com www.sciencedirect.com
    Genetically encoded fluorescent reporters to visualize α-synuclein pathology in live brain
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S0092867426001637
  18. Feb 2026
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Spatial transcriptomics reveals the molecular signatures of prodromal and advanced α-synucleinopathy
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12927100/
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mapping cellular vulnerability in Parkinson’s disease using retro-AAVs and preformed α-synuclein fibrils
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12859986/
  21. Jan 2026
  22. www.sciencedirect.com www.sciencedirect.com
    A monoclonal antibody targeting the C-terminal of α-synuclein fibrils mitigates pathology in a Parkinson’s disease model
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124725016699
  23. www.sciencedirect.com www.sciencedirect.com
    Skin-derived α-synuclein strains from PD, DLB, and MSA induce distinct intracellular pathology and neurodegeneration
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S0021925825028571
  24. www.sciencedirect.com www.sciencedirect.com
    Protocol for dissecting the aggregation-prone protein interactome with optogenetic-induced aggregation and biotin labeling proximity assay
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2666166725007099
  25. Nov 2025
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CHCHD2 mutant mice link mitochondrial deficits to PD pathophysiology
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12617525/
  27. www.science.org www.science.org
    CHCHD2 mutant mice link mitochondrial deficits to PD pathophysiology
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    science.org/doi/10.1126/sciadv.adu0726
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Fc-Modified IVIG with Enhanced Blood–Brain Barrier Penetration Ameliorates Cognitive Deficits and Neuropathology in A53T α-Synuclein Transgenic Mice
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12618800/
  29. www.sciencedirect.com www.sciencedirect.com
    In situ amplification of α-synuclein amyloid fibril reveals a distinct polymorph related to Parkinson’s disease and dementia with Lewy body
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124725013361
  30. www.biorxiv.org www.biorxiv.org
    Parkinson’s disease modeling in regenerative spiny mice (Acomys dimidiatus) captures key disease-relevant behavioral, histological, and molecular signatures
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    biorxiv.org/content/10.1101/2025.11.06.687049v1
  31. Oct 2025
  32. www.sciencedirect.com www.sciencedirect.com
    TREM2 deficiency aggravates neuroinflammatory response and cognitive impairment via disease-associated microglia in Parkinson’s disease models
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S019701862500141X
  33. Sep 2025
  34. www.sciencedirect.com www.sciencedirect.com
    A rare genetic variant confers resistance to neurodegeneration across multiple neurological disorders by augmenting selective autophagy
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S0896627325006245
  35. www.sciencedirect.com www.sciencedirect.com
    α-Synuclein aggregates inhibit ESCRT-III through sequestration and collateral degradation
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1097276525007075
  36. Aug 2025
  37. www.sciencedirect.com www.sciencedirect.com
    Structural insights into the activation of TMEM175 by small molecule
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S0896627325005562
  38. www.biorxiv.org www.biorxiv.org
    CD11b Activation Reduces Myeloid Brain Infiltration and Mitigates Synucleinopathy in a Model of Parkinson’s Disease
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    biorxiv.org/content/10.1101/2025.08.11.669712v1
  39. Jul 2025
  40. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Increased burden of rare risk variants across gene expression networks predisposes to sporadic Parkinson’s disease
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12258067/
  41. www.eneuro.org www.eneuro.org
    SCD Inhibition Protects from α-Synuclein-Induced Neurotoxicity But Is Toxic to Early Neuron Cultures
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    eneuro.org/content/8/4/ENEURO.0166-21.2021
  42. Jun 2025
  43. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Combining light-induced aggregation and biotin proximity labeling implicates endolysosomal proteins in early α-synuclein oligomerization
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12221657/
  44. www.sciencedirect.com www.sciencedirect.com
    Low-grade chronic inflammatory stimulation alleviates α‑syn accumulation in Parkinson's disease by activating autophagy to promote neuronal survival in the Thy1-h[A30P]α-syn mouse model
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S0166432825002906
  45. 52.53.155.43 52.53.155.43
    PDF-html.html
    2
    Visit annotations in context

    Tags

    Annotators

    URL

    52.53.155.43/4a6a966e38c69c020e4968e09e6c8a3a036414fb/fcaf224-html.html
  46. May 2025
  47. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Synaptic vesicle-omics in mice captures signatures of aging and synucleinopathy
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12046008/
  48. link.springer.com link.springer.com
    Microglia-driven inflammation induces progressive tauopathies and synucleinopathies
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    link.springer.com/article/10.1038/s12276-025-01450-z
  49. www.sciencedirect.com www.sciencedirect.com
    SLC7A11 is an unconventional H+ transporter in lysosomes
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S0092867425004064
  50. Apr 2025
  51. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Alpha-Synuclein Phosphomimetic Y39E and S129D Knock-In Mice Show Cytosolic Alpha-Synuclein Localization without Developing Neurodegeneration or Motor Deficits
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11998964/
  52. www.sciencedirect.com www.sciencedirect.com
    Early A-synuclein aggregation decreases corticostriatal glutamate drive and synapse density
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S0969996125001342
  53. www.sciencedirect.com www.sciencedirect.com
    Fibril fuzzy coat is important for α-synuclein pathological transmission activity
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S0896627325002193
  54. 52.53.155.43 52.53.155.43
    PDF-html.html
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    52.53.155.43/6343470ab662b00750e766dae62c29226c242386/PDF-html.html
  55. Mar 2025
  56. link.springer.com link.springer.com
    Proximity proteomics reveals unique and shared pathological features between multiple system atrophy and Parkinson’s disease
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    link.springer.com/article/10.1186/s40478-025-01958-5
  57. www.sciencedirect.com www.sciencedirect.com
    Single extracellular vesicle detection assay identifies membrane-associated α-synuclein as an early-stage biomarker in Parkinson’s disease
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2666379125000722
  58. Feb 2025
  59. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Female mice exhibit resistance to disease progression despite early pathology in a transgenic mouse model inoculated with alpha-synuclein fibrils
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11846974/
  60. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Decreased levels of phosphorylated synuclein in plasma are correlated with poststroke cognitive impairment
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11801306/
  61. www.biorxiv.org www.biorxiv.org
    Network analysis of α-synuclein pathology progression reveals p21-activated kinases as regulators of vulnerability
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    biorxiv.org/content/10.1101/2024.10.22.619411v1
  62. academic.oup.com academic.oup.com
    Intrinsic link between PGRN and Gba1 D409V mutation dosage in potentiating Gaucher disease
    7
    Visit annotations in context

    Tags

    Annotators

    URL

    academic.oup.com/hmg/article-abstract/33/20/1771/7727363
  63. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Synaptic vesicle endocytosis deficits underlie GBA-linked cognitive dysfunction in Parkinson’s disease and Dementia with Lewy bodies
    7
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11703330/
  64. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Synaptic vesicle endocytosis deficits underlie GBA-linked cognitive dysfunction in Parkinson’s disease and Dementia with Lewy bodies
    7
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11527026/
  65. 52.53.155.43 52.53.155.43
    awaf051-html.html
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    52.53.155.43/ad3dfd72e4bbedea4b2fe45e2acb356095b82879/awaf051-html.html
  66. 52.53.155.43 52.53.155.43
    Knockout of the LRRK2-counteracting RAB phosphatase PPM1H disrupts axonal autophagy and exacerbates alpha-synuclein aggregation
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    52.53.155.43/01dd9728947fbe4affbd9309aaacf50825c24057/2024.10.14.618089.full-html.html
  67. Jan 2025
  68. academic.oup.com academic.oup.com
    Intrinsic link between PGRN and Gba1 D409V mutation dosage in potentiating Gaucher disease
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    academic.oup.com/hmg/article-abstract/33/20/1771/7727363
  69. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Synaptic vesicle endocytosis deficits underlie GBA-linked cognitive dysfunction in Parkinson’s disease and Dementia with Lewy bodies
    8
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11703330/
  70. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Synaptic vesicle endocytosis deficits underlie GBA-linked cognitive dysfunction in Parkinson’s disease and Dementia with Lewy bodies
    16
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11527026/
  71. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Recursive seed amplification detects distinct α-synuclein strains in cerebrospinal fluid of patients with Parkinson’s disease
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11749544/
  72. link.springer.com link.springer.com
    Motor cortical neuronal hyperexcitability associated with α-synuclein aggregation
    2
    Visit annotations in context

    Tags

    Annotators

    URL

    link.springer.com/article/10.1038/s41531-024-00867-z
  73. www.sciencedirect.com www.sciencedirect.com
    14–3-3θ phosphorylation exacerbates alpha-synuclein aggregation and toxicity
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S0969996125000178
  74. www.sciencedirect.com www.sciencedirect.com
    G6PD deficiency triggers dopamine loss and the initiation of Parkinson’s disease pathogenesis
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124724015298
  75. Dec 2024
  76. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Protocol for generation of PD-modeling-induced neurons and detection of α-synuclein forms
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11609654/
  77. Nov 2024
  78. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dual inhibition of aminoacyl-tRNA synthetase interacting multifunctional protein-2 and α-synuclein by steroid derivative is neuroprotective in Parkinson’s model
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11576395/
  79. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Systemic inflammation accelerates neurodegeneration in a rat model of Parkinson’s disease overexpressing human alpha synuclein
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11538257/
  80. Oct 2024
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Modulation of cannabinoid receptor 2 alters neuroinflammation and reduces formation of alpha-synuclein aggregates in a rat model of nigral synucleinopathy
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC11438102/
  82. Sep 2024
  83. www.biorxiv.org www.biorxiv.org
    Comparing alpha-synuclein-interactomes between multiple systems atrophy and Parkinson’s disease reveals unique and shared pathological features
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    biorxiv.org/content/10.1101/2024.09.20.613717v1
  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CHCHD2 mutant mice display mitochondrial protein accumulation and disrupted energy metabolism
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC11384018/
  85. Aug 2024
  86. www.sciencedirect.com www.sciencedirect.com
    Neuromodulation modifies α-synuclein spreading dynamics in vivo and the pattern is predicted by changes in whole-brain function
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1935861X24001360
  87. Jul 2024
  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Rapid iPSC inclusionopathy models shed light on formation, consequence, and molecular subtype of α-synuclein inclusions
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC11377155/
  89. www.sciencedirect.com www.sciencedirect.com
    Excitatory synaptic structural abnormalities produced by templated aggregation of α-syn in the basolateral amygdala
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S0969996124001955
  90. Jun 2024
  91. Local file Local file
    Untitled document
    1
    1. scibot 06 Jun 2024
      Figure S3Figure S3. List of the antibodies used in this study (related to Figures 1 to 9)A. Antibodies used for the detection of total aSyn.B. Antibodies used for the detection of α-syn phosphorylated at residue S129.C. Other antibodies used in the study.

      DOI: 10.1101/2022.03.30.486322

      Resource: (Abcam Cat# ab51253, RRID:AB_869973)

      Curator: @bandrow

      SciCrunch record: RRID:AB_869973

      What is this?
      RRID:AB_869973

    Tags

    Annotators

  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Alpha-synuclein aggregates are phosphatase resistant
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC11141014/
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Aplp1 interacts with Lag3 to facilitate transmission of pathologic α-synuclein
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC11143359/
  94. May 2024
  95. www.biorxiv.org www.biorxiv.org
    Sex-focused analyses of M83 A53T hemizygous mouse model with recombinant human alpha-synuclein preformed fibril injection identifies female resilience to disease progression: A combined magnetic resonance imaging and behavioural study
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    biorxiv.org/content/10.1101/2024.05.24.595642v1
  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neither alpha-synuclein fibril strain nor host murine genotype influences seeding efficacy
    2
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC11109094/
  97. www.biorxiv.org www.biorxiv.org
    Mouse α-synuclein fibrils are structurally and functionally distinct from human fibrils associated with Lewy body diseases
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    biorxiv.org/content/10.1101/2024.05.09.593334v1
  98. www.biorxiv.org www.biorxiv.org
    Adult-Onset Deletion of ATP13A2 in Mice Induces Progressive Nigrostriatal Pathway Dopaminergic Degeneration and Lysosomal Abnormalities
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    biorxiv.org/content/10.1101/2024.01.25.577280v1
  99. www.biorxiv.org www.biorxiv.org
    Gut-Initiated Alpha Synuclein Fibrils Drive Parkinson’s Disease Phenotypes: Temporal Mapping of non-Motor Symptoms and REM Sleep Behavior Disorder
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    biorxiv.org/content/10.1101/2024.04.22.590542v1
  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Alpha-synuclein aggregates are phosphatase resistant
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC11030248/
  101. Apr 2024
  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In vivo bioluminescence imaging of the intracerebral fibroin-controlled AAV-α-synuclein diffusion for monitoring the central nervous system and peripheral expression
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC11055870/
  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Enhanced Spine Stability and Survival Lead to Increases in Dendritic Spine Density as an Early Response to Local Alpha-Synuclein Overexpression in Mouse Prefrontal Cortex
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC11052719/
  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Generation of G51D and 3D mice reveals decreased α-synuclein tetramer-monomer ratios promote Parkinson’s disease phenotypes
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC10904737/
  105. www.nature.com www.nature.com
    Genetic and pharmacological reduction of CDK14 mitigates synucleinopathy
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    nature.com/articles/s41419-024-06534-8
  106. Feb 2024
  107. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Nigrostriatal tau pathology in parkinsonism and Parkinson’s disease
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC10834249/
  108. Dec 2023
  109. www.sciencedirect.com www.sciencedirect.com
    Serine-129 phosphorylation of α-synuclein is an activity-dependent trigger for physiologic protein-protein interactions and synaptic function
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S0896627323008942
  110. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NEMO reshapes the α-Synuclein aggregate interface and acts as an autophagy adapter by co-condensation with p62
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC10730909/
  111. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Combining fibril-induced alpha-synuclein aggregation and 6-hydroxydopamine in a mouse model of Parkinson's disease and the effect of cerebral dopamine neurotrophic factor on the induced neurodegeneration
    2
    Visit annotations in context

    Tags

    Annotators

    URL

    onlinelibrary.wiley.com/doi/10.1111/ejn.16196
  112. Oct 2023
  113. www.sciencedirect.com www.sciencedirect.com
    α-Synuclein-dependent increases in PIP5K1γ drive inositol signaling to promote neurotoxicity
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124723012561
  114. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Neuroanatomical and cognitive biomarkers of alpha-synuclein propagation in a mouse model of synucleinopathy prior to onset of motor symptoms
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    onlinelibrary.wiley.com/doi/10.1111/jnc.15967
  115. www.cell.com www.cell.com
    Impaired pre-synaptic plasticity and visual responses in Auxilin knockout mice
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    cell.com/iscience/abstract/S2589-0042(23)01919-3
  116. www.cell.com www.cell.com
    Fiber deprivation and microbiome-borne curli shift gut bacterial populations and accelerate disease in a mouse model of Parkinson’s disease
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    cell.com/cell-reports/abstract/S2211-1247(23)01082-3
  117. Aug 2023
  118. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    α-Synuclein pathology in post-mortem retina and optic nerve is specific for α-synucleinopathies
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC10462645/
  119. www.sciencedirect.com www.sciencedirect.com
    Suppression of α-synuclein propagation after intrastriatal injection in FABP3 null mice
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S0006899321001086
  120. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Parkinson’s disease neurons exhibit alterations in mitochondrial quality control proteins
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC10409763/
  121. Jul 2023
  122. 52.53.155.43 52.53.155.43
    NEMO reshapes the protein aggregate interface and promotes aggrephagy by co-condensation with p62
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    52.53.155.43/5185b06857919afc7fae38712332798a8a903a3a/2023.06.05.543428v1.full-html.html
  123. Jun 2023
  124. www.sciencedirect.com www.sciencedirect.com
    Advanced human iPSC-based preclinical model for Parkinson’s disease with optogenetic alpha-synuclein aggregation
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1934590923002114
  125. Mar 2023
  126. www.sciencedirect.com www.sciencedirect.com
    Dopamine transporter and synaptic vesicle sorting defects underlie auxilin-associated Parkinson’s disease
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124723002425
  127. Jan 2023
  128. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Neuronopathic GBA1L444P mutation accelerates Glucosylsphingosine levels and formation of hippocampal alpha-synuclein inclusions
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC9864632/
  129. Nov 2022
  130. www.sciencedirect.com www.sciencedirect.com
    Grabody B, an IGF1 receptor-based shuttle, mediates efficient delivery of biologics across the blood-brain barrier
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2667237522002351
  131. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Early and extensive alterations of glial connexins, distal oligodendrogliopathy type demyelination, and nodal/paranodal pathology are characteristic of multiple system atrophy
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    onlinelibrary.wiley.com/doi/10.1111/bpa.13131
  132. www.sciencedirect.com www.sciencedirect.com
    Mesoscale connections and gene expression empower whole-brain modeling of α-synuclein spread, aggregation, and decay dynamics
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124722015029
  133. journals.lww.com journals.lww.com
    Neuroprotective effects of insulin-like growth factor-2 in... : Neural Regeneration Research
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    journals.lww.com/nrronline/Fulltext/2023/05000/Neuroprotective_effects_of_insulin_like_growth.29.aspx
  134. Sep 2022
  135. link.springer.com link.springer.com
    Stress-inducible phosphoprotein 1 (HOP/STI1/STIP1) regulates the accumulation and toxicity of α-synuclein in vivo
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    link.springer.com/article/10.1007/s00401-022-02491-8
  136. Jun 2022
  137. www.sciencedirect.com www.sciencedirect.com
    Parkinson’s disease-risk protein TMEM175 is a proton-activated proton channel in lysosomes
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S0092867422006523
  138. www.sciencedirect.com www.sciencedirect.com
    Neuronal NLRP3 is a parkin substrate that drives neurodegeneration in Parkinson’s disease
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S0896627322004500
  139. May 2022
  140. www.sciencedirect.com www.sciencedirect.com
    Skin alpha-synuclein deposit patterns: A predictor of Parkinson's disease subtypes
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2352396422002572
  141. Mar 2022
  142. link.springer.com link.springer.com
    Microglia phenotypes are associated with subregional patterns of concomitant tau, amyloid-β and α-synuclein pathologies in the hippocampus of patients with Alzheimer’s disease and dementia with Lewy bodies
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    link.springer.com/article/10.1186/s40478-022-01342-7
  143. Feb 2022
  144. www.sciencedirect.com www.sciencedirect.com
    Vortioxetine ameliorates motor and cognitive impairments in the rotenone-induced Parkinson's disease via targeting TLR-2 mediated neuroinflammation
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S0028390822000363
  145. Dec 2021
  146. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Schwann cells differentiated from skin-derived precursors provide neuroprotection via autophagy inhibition in a cellular model of Parkinson's disease
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC8643066/
  147. Sep 2021
  148. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Prolyl oligopeptidase inhibition reduces alpha-synuclein aggregation in a cellular model of multiple system atrophy
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    onlinelibrary.wiley.com/doi/10.1111/jcmm.16910
  149. Aug 2021
  150. www.physiology.org www.physiology.org
    Altered gastric tone and motility response to brain-stem dopamine in a rat model of parkinsonism
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    physiology.org/doi/abs/10.1152/ajpgi.00076.2019
  151. link.springer.com link.springer.com
    Untitled document
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    link.springer.com/article/10.1186/s40478-019-0679-5
  152. Jul 2021
  153. actaneurocomms.biomedcentral.com actaneurocomms.biomedcentral.com
    Untitled document
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    actaneurocomms.biomedcentral.com/articles/10.1186/s40478-019-0679-5
  154. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Sensitivity and specificity of phospho‐Ser129 α‐synuclein monoclonal antibodies
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    onlinelibrary.wiley.com/doi/full/10.1002/cne.24468
  155. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Visualization of early oligomeric α-synuclein pathology and its impact on the dopaminergic system in the (Thy-1)-h[A30P]α-syn transgenic mouse model
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    onlinelibrary.wiley.com/doi/10.1002/jnr.24927
  156. www.sciencedirect.com www.sciencedirect.com
    Altered conformation of α-synuclein drives dysfunction of synaptic vesicles in a synaptosomal model of Parkinson’s disease
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124721007099
  157. Jun 2021
  158. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Templated α-synuclein inclusion formation is independent of endogenous tau
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC8213444/
  159. May 2021
  160. www.sciencedirect.com www.sciencedirect.com
    α-Synuclein mutation impairs processing of endomembrane compartments and promotes exocytosis and seeding of α-synuclein pathology
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124721004332
  161. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In situ architecture of neuronal α-Synuclein inclusions
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC8046968/
  162. Apr 2021
  163. www.sciencedirect.com www.sciencedirect.com
    Suppression of α-synuclein propagation after intrastriatal injection in FABP3 null mice
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S0006899321001086
  164. Mar 2021
  165. onlinelibrary.wiley.com onlinelibrary.wiley.com
    α‐Synuclein Abnormalities Trigger Focal Tau Pathology, Spreading to Various Brain Areas in Parkinson’s Disease
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    onlinelibrary.wiley.com/doi/10.1111/jnc.15257
  166. Feb 2021
  167. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Brain-Gut Interactions: Altered gastric tone and motility response to brain-stem dopamine in a rat model of parkinsonism
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC6689734/
  168. Nov 2020
  169. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Distinct alpha‐Synuclein species induced by seeding are selectively cleared by the Lysosome or the Proteasome in neuronally differentiated SH‐SY5Y cells
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    onlinelibrary.wiley.com/doi/10.1111/jnc.15174
  170. Oct 2020
  171. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Deficiency of the serine peptidase Kallikrein 6 does not affect the levels and the pathological accumulation of a‐synuclein in mouse brain
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    onlinelibrary.wiley.com/doi/10.1111/jnc.15199
  172. Sep 2020
  173. onlinelibrary.wiley.com onlinelibrary.wiley.com
    H63D variant of the homeostatic iron regulator (HFE) gene alters α‐synuclein expression, aggregation, and toxicity
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    onlinelibrary.wiley.com/doi/10.1111/jnc.15107
  174. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Long-Term Exposure to PFE-360 in the AAV-α-Synuclein Rat Model: Findings and Implications
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC6978918/
  175. www.jneurosci.org www.jneurosci.org
    Doublecortin like kinase 1 regulates α-Synuclein levels and toxicity
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    jneurosci.org/content/40/2/459
  176. Jan 2020
  177. link.springer.com link.springer.com
    Alzheimer’s disease tau is a prominent pathology in LRRK2 Parkinson’s disease
    2
    Visit annotations in context

    Tags

    Annotators

    URL

    link.springer.com/article/10.1186/s40478-019-0836-x
  178. www.frontiersin.org www.frontiersin.org
    Upregulated Expression of MicroRNA-204-5p Leads to the Death of Dopaminergic Cells by Targeting DYRK1A-Mediated Apoptotic Signaling Cascade
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    frontiersin.org/article/10.3389/fncel.2019.00399/full
  179. www.sciencedirect.com www.sciencedirect.com
    Glucocerebrosidase Activity Modulates Neuronal Susceptibility to Pathological α-Synuclein Insult
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S0896627319310463
  180. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC6402832/
  181. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC6391792/
  182. Nov 2017
  183. onlinelibrary.wiley.com onlinelibrary.wiley.com
    “Prion‐like” propagation of the synucleinopathy of M83 transgenic mice depends on the mouse genotype and type of inoculum
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    onlinelibrary.wiley.com/doi/10.1111/jnc.14139/full
  184. link.springer.com link.springer.com
    Prion-Like Seeding of Misfolded α-Synuclein in the Brains of Dementia with Lewy Body Patients in RT-QUIC
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    link.springer.com/article/10.1007/s12035-017-0624-1