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Jun 2025
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High-content image-based pooled screens reveal regulators of synaptogenesis

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1. scibot 25 Jun 2025
  
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  DOI: 10.1016/j.celrep.2025.115889
  
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sciencedirect.com/science/article/pii/S2211124725006606
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Distinct functional domains of Dystroglycan regulate inhibitory synapse formation and maintenance in cerebellar Purkinje cells

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1. scibot 11 Jun 2025
  
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  DOI: 10.1038/s42003-025-08323-1
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12141699/
May 2025
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Partial normalization of hippocampal oscillatory activity during sleep in TgF344-AD rats coincides with increased cholinergic synapses at early-plaque stage of Alzheimer’s disease

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1. scibot 21 May 2025
  
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  DOI: 10.1186/s40478-025-02016-w
  
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link.springer.com/article/10.1186/s40478-025-02016-w
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The NLRP3 inflammasome in microglia regulates repetitive behavior by modulating NMDA glutamate receptor functions

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  DOI: 10.1016/j.celrep.2025.115656
  
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cell.com/cell-reports/fulltext/S2211-1247(25)00427-9
Dec 2024
journals.plos.org journals.plos.org

Axons compensate for biophysical constraints of variable size to uniformize their action potentials

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1. scibot 05 Dec 2024
  
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  DOI: 10.1371/journal.pbio.3002929
  
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journals.plos.org/plosbiology/article
Nov 2024
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miRNA-mediated control of gephyrin synthesis drives sustained inhibitory synaptic plasticity

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1. scibot 14 Nov 2024
  
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  DOI: 10.1038/s44319-024-00253-z
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11549329/
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TRPM2 and CaMKII Signaling Drives Excessive GABAergic Synaptic Inhibition Following Ischemia

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  DOI: 10.1523/JNEUROSCI.1762-23.2024
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11079974/
Oct 2024
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The TMEM132B-GABAA receptor complex controls alcohol actions in the brain

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  DOI: 10.1016/j.cell.2024.09.006
  
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  DOI: 10.1016/j.cell.2024.09.006
  
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sciencedirect.com/science/article/pii/S0092867424010249
Sep 2024
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MDGAs perform activity-dependent synapse type-specific suppression via distinct extracellular mechanisms

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1. scibot 26 Sep 2024
  
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  DOI: 10.1073/pnas.2322978121
  
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pnas.org/doi/10.1073/pnas.2322978121
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GABAergic neuronal lineage development determines clinically actionable targets in diffuse hemispheric glioma, H3G34-mutant

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  DOI: 10.1016/j.ccell.2024.08.006
  
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sciencedirect.com/science/article/pii/S1535610824003052
Aug 2024
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Postsynaptic gephyrin clustering controls the development of adult‐born granule cells in the olfactory bulb

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1. scibot 02 Aug 2024
  
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  DOI: 10.1002/cne.23776
  
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2. scibot 02 Aug 2024
  
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  DOI: 10.1002/cne.23776
  
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onlinelibrary.wiley.com/doi/10.1002/cne.23776/full
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Spatiotemporal expression analysis of the growth factor receptor SorCS3

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1. scibot 02 Aug 2024
  
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  DOI: 10.1002/cne.23606
  
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onlinelibrary.wiley.com/doi/10.1002/cne.23606/full
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In vivo clonal overexpression of neuroligin 3 and neuroligin 2 in neurons of the rat cerebral cortex: Differential effects on GABAergic synapses and neuronal migration

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1. scibot 02 Aug 2024
  
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  DOI: 10.1002/cne.23740
  
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onlinelibrary.wiley.com/doi/10.1002/cne.23740/full
Jun 2024
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Investigating GABA Neuron–Specific Androgen Receptor Knockout in two Hyperandrogenic Models of PCOS

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1. scibot 08 Jun 2024
  
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  DOI: 10.1210/endocr/bqae060
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11151696/
May 2024
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Generation and enrichment of cerebellar GABAergic interneurons from human induced pluripotent stem cells and intracellular calcium measurements

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1. scibot 16 May 2024
  
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  DOI: 10.1016/j.xpro.2024.102936
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11101973/
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Nr4a1 regulates cell-specific transcriptional programs in inhibitory GABAergic interneurons

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1. scibot 16 May 2024
  
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  DOI: 10.1016/j.neuron.2024.03.018
  
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sciencedirect.com/science/article/pii/S089662732400196X
Apr 2024
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Kit Ligand and Kit receptor tyrosine kinase sustain synaptic inhibition of Purkinje cells

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1. scibot 03 Apr 2024
  
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  DOI: 10.7554/eLife.89792
  
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pmc.ncbi.nlm.nih.gov/articles/PMC10972566/
Mar 2024
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Nausea-induced suppression of feeding is mediated by central amygdala Dlk1-expressing neurons

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1. scibot 29 Mar 2024
  
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  DOI: 10.1016/j.celrep.2024.113990
  
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sciencedirect.com/science/article/pii/S2211124724003188
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Inhibitory CCK+ basket synapse defects in mouse models of dystroglycanopathy

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1. scibot 19 Mar 2024
  
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  DOI: 10.7554/eLife.87965
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10942650/
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Anterograde trans-neuronal labeling of striatal interneurons in relation to dopamine neurons in the substantia nigra pars compacta

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1. scibot 16 Mar 2024
  
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  DOI: 10.3389/fnana.2024.1325368
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10933013/
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Neuron type-specific proteomics reveals distinct Shank3 proteoforms in iPSNs and dSPNs lead to striatal synaptopathy in Shank3B–/– mice

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  DOI: 10.1038/s41380-024-02493-w
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11412912/
Feb 2024
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Modeling the precise interaction of glioblastoma with human brain region-specific organoids

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1. scibot 28 Feb 2024
  
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  DOI: 10.1016/j.isci.2024.109111
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10882168/
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Different Purkinje cell pathologies cause specific patterns of progressive gait ataxia in mice

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  DOI: 10.1016/j.nbd.2024.106422
  
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sciencedirect.com/science/article/pii/S0969996124000214
Dec 2023
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S-SCAM is essential for synapse formation

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  DOI: 10.3389/fncel.2023.1182493
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10690602/
Nov 2023
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Acute reorganization of postsynaptic GABAA receptors reveals the functional impact of molecular nanoarchitecture at inhibitory synapses

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1. scibot 10 Nov 2023
  
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  DOI: 10.1016/j.celrep.2023.113331
  
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sciencedirect.com/science/article/pii/S2211124723013438
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GABAergic-like dopamine synapses in the brain

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  DOI: 10.1016/j.celrep.2023.113239
  
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sciencedirect.com/science/article/pii/S2211124723012512
Oct 2023
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Distinct mechanisms drive sequential internalization and degradation of GABAARs during global ischemia and reperfusion injury

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  DOI: 10.1016/j.isci.2023.108061
  
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cell.com/iscience/abstract/S2589-0042(23)02138-7
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Human pallial MGE-type GABAergic interneuron cell therapy for chronic focal epilepsy

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1. scibot 13 Oct 2023
  
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  DOI: 10.1016/j.stem.2023.08.013
  
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sciencedirect.com/science/article/pii/S1934590923002965
Aug 2023
rupress.org rupress.org

Presynapses contain distinct actin nanostructures

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  RRID:AB_887869
  
  DOI: 10.1083/jcb.202208110
  
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  DOI: 10.1083/jcb.202208110
  
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rupress.org/jcb/article/222/10/e202208110/276185/Presynapses-contain-distinct-actin
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Different mechanisms of synapsin-induced vesicle clustering at inhibitory and excitatory synapses

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  DOI: 10.1016/j.celrep.2023.113004
  
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sciencedirect.com/science/article/pii/S221112472301015X
Jun 2023
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Early molecular layer interneuron hyperactivity triggers Purkinje neuron degeneration in SCA1

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  DOI: 10.1016/j.neuron.2023.05.016
  
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sciencedirect.com/science/article/pii/S0896627323003896
May 2023
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Neuron-specific protein expression at striatal excitatory synapses

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1. scibot 18 May 2023
  
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  RRID:AB_887869
  
  DOI: 10.1101/2023.03.16.532957
  
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biorxiv.org/content/10.1101/2023.03.16.532957v1
Apr 2023
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LPS induces microglial activation and GABAergic synaptic deficits in the hippocampus accompanied by prolonged cognitive impairment

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1. scibot 23 Apr 2023
  
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  DOI: 10.1038/s41598-023-32798-9
  
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link.springer.com/article/10.1038/s41598-023-32798-9
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The complement inhibitor CD59 is required for GABAergic synaptic transmission in the dentate gyrus

1
1. scibot 08 Apr 2023
  
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  DOI: 10.1016/j.celrep.2023.112349
  
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Human cortical interneurons optimized for grafting specifically integrate, abort seizures, and display prolonged efficacy without over-inhibition

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The Regional and Cellular Distribution of GABAA Receptor Subunits in the Human Amygdala

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Altered basal forebrain function during whole-brain network activity at pre- and early-plaque stages of Alzheimer’s disease in TgF344-AD rats

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Acute rapamycin rescues the hyperexcitable phenotype of accumbal medium spiny neurons in the valproic acid rat model of autism spectrum disorder

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Chronic androgen excess in female mice does not impact luteinizing hormone pulse frequency or putative GABAergic inputs to GnRH neurons

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LRRTM3 regulates activity-dependent synchronization of synapse properties in topographically connected hippocampal neural circuits

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Inhibition, but not excitation, recovers from partial cone loss with greater spatiotemporal integration, synapse density, and frequency

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Stepwise disassembly of GABAergic synapses during pathogenic excitotoxicity

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Prenatal interleukin 6 elevation increases glutamatergic synapse density and disrupts hippocampal connectivity in offspring

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Axonal CB1 receptors mediate inhibitory bouton formation via cAMP increase and PKA

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Prenatal androgen exposure alters KNDy neurons and their afferent network in a model of polycystic ovarian syndrome

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Morphological assessment of GABA and glutamate inputs to GnRH neurons in intact female mice using expansion microscopy

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Reprogramming reactive glia into interneurons reduces chronic seizure activity in a mouse model of mesial temporal lobe epilepsy

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Transient expression of a GABA receptor subunit during early development is critical for inhibitory synapse maturation and function

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Spatiotemporal expression analysis of the growth factor receptor SorCS3

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Primary Cilia Signaling Shapes the Development of Interneuronal Connectivity - ScienceDirect

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Genetic Ablation of All Cerebellins Reveals Synapse Organizer Functions in Multiple Regions Throughout the Brain

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Puncta of Neuronal Nitric Oxide Synthase (nNOS) Mediate NMDA Receptor Signaling in the Auditory Midbrain

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Morphological evidence indicate a role for microglia in shaping the polycystic ovary syndrome (PCOS)-like brain

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Anatomical and Behavioral Investigation of C1ql3 in the Mouse Suprachiasmatic Nucleus - Kylie S. Chew, Diego C. Fernandez, Samer Hattar, Thomas C. Südhof, David C. Martinelli, 2017

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Task Division within the Prefrontal Cortex: Distinct Neuron Populations Selectively Control Different Aspects of Aggressive Behavior via the Hypothalamus

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Dorsal and ventral mossy cells differ in their axonal projections throughout the dentate gyrus of the mouse hippocampus

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Noise Exposure Alters Glutamatergic and GABAergic Synaptic Connectivity in the Hippocampus and Its Relevance to Tinnitus

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Neuronal Autophagy Regulates Presynaptic Neurotransmission by Controlling the Axonal Endoplasmic Reticulum

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Loss of IQSEC3 Disrupts GABAergic Synapse Maintenance and Decreases Somatostatin Expression in the Hippocampus

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Synaptic organisation and behaviour-dependent activity of mGluR8a-innervated GABAergic trilaminar cells projecting from the hippocampus to the subiculum

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Dysregulation of BRD4 Function Underlies the Functional Abnormalities of MeCP2 Mutant Neurons

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Local miRNA-Dependent Translational Control of GABAAR Synthesis during Inhibitory Long-Term Potentiation

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Opposite Control of Excitatory and Inhibitory Synapse Formation by Slitrk2 and Slitrk5 on Dopamine Neurons Modulates Hyperactivity Behavior

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Different dendritic domains of the GnRH neuron underlie the pulse and surge modes of GnRH secretion in female mice

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Inputs from Sequentially Developed Parallel Fibers Are Required for Cerebellar Organization

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Neuroligin-4 Regulates Excitatory Synaptic Transmission in Human Neurons

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Prenatal Testosterone Exposure Alters GABAergic Synaptic Inputs to GnRH and KNDy Neurons in a Sheep Model of Polycystic Ovarian Syndrome

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Lrfn2-Mutant Mice Display Suppressed Synaptic Plasticity and Inhibitory Synapse Development and Abnormal Social Communication and Startle Response

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p75 Neurotrophin Receptor Activation Regulates the Timing of the Maturation of Cortical Parvalbumin Interneuron Connectivity and Promotes Juvenile-like Plasticity in Adult Visual Cortex

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Semaphorin4D Induces Inhibitory Synapse Formation by Rapid Stabilization of Presynaptic Boutons via MET Coactivation

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Selective rab11 transport and the intrinsic regenerative ability of CNS axons

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Modeling a Neurexin-3α human mutation in mouse neurons identifies a novel role in the regulation of transsynaptic signaling and neurotransmitter release at excitatory synapses

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Synaptic Connectivity and Cortical Maturation Are Promoted by the ω-3 Fatty Acid Docosahexaenoic Acid

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Autism and Schizophrenia-Associated CYFIP1 Regulates the Balance of Synaptic Excitation and Inhibition

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Nanoscale Subsynaptic Domains Underlie the Organization of the Inhibitory Synapse

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Untitled document

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Loss of Mecp2 Causes Atypical Synaptic and Molecular Plasticity of Parvalbumin-Expressing Interneurons Reflecting Rett Syndrome–Like Sensorimotor Defects

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Dystroglycan Maintains Inner Limiting Membrane Integrity to Coordinate Retinal Development

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Behavior-Dependent Activity and Synaptic Organization of Septo-hippocampal GABAergic Neurons Selectively Targeting the Hippocampal CA3 Area

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Inhibitory and excitatory amino acid neurotransmitters are utilized by the projection from the dorsal deep mesencephalic nucleus to the sublaterodorsal nucleus REM sleep induction zone

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Nov 2017
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Few, Activity-Dependent, and Ubiquitous VGLUT1/VGAT Terminals in Rat and Mouse Brain

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Primary Cilia Signaling Shapes the Development of Interneuronal Connectivity - ScienceDirect

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Assembly of Excitatory Synapses in the Absence of Glutamatergic Neurotransmission

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NCAM Regulates Inhibition and Excitability in Layer 2/3 Pyramidal Cells of Anterior Cingulate Cortex

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ELKS controls the pool of readily releasable vesicles at excitatory synapses through its N-terminal coiled-coil domains

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Dlg5 Regulates Dendritic Spine Formation and Synaptogenesis by Controlling Subcellular N-Cadherin Localization

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Spatiotemporal expression analysis of the growth factor receptor SorCS3

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In vivo clonal overexpression of neuroligin 3 and neuroligin 2 in neurons of the rat cerebral cortex: Differential effects on GABAergic synapses and neuronal migration

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